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<br /> DERMATOLOGY<br /> EMJ Dermatol. 2020 Suppl 1 • europeanmedical-journal.com<br /> INSIDE<br /> Treat Psoriasis:<br /> A New Era is Coming<br /> New Insights into Dimethyl<br /> Fumarate, an Oral Therapy<br /> for the Treatment of<br /> Plaque Psoriasis<br /> Treat Psoriasis: A New Era is Coming<br /> This symposium took place on June 14th 2019 as part of the 24th World<br /> Congress of Dermatology (WCD) in Milan, Italy<br /> Chairpeople: Diamant Thąci,1 Giampiero Girolomoni2<br /> Speakers: Antonio Costanzo,3 Diamant Thąci,1 Stefano Piaserico4<br /> 1. Institute of Comprehensive Center for Inflammation Medicine, University of<br /> Lübeck, Lübeck, Germany<br /> 2. University of Verona School of Medicine, Verona, Italy<br /> 3. Dermatology Unit and Skin Pathology Laboratory, Humanitas University, Milan,<br /> Italy<br /> 4. University of Padova, Padua, Italy<br /> Disclosure: Prof Co<a title="EMJ Dermatol. 2020 Suppl 1 page 1" href="http://viewer.zmags.com/publication/0214a2a9?page=1"> DERMATOLOGY EMJ Dermatol. 2020 Suppl 1 • european</a> <a title="EMJ Dermatol. 2020 Suppl 1 page 2" href="http://viewer.zmags.com/publication/0214a2a9?page=2"> Treat Psoriasis: A New Era is Coming This sympos</a> <a title="EMJ Dermatol. 2020 Suppl 1 page 3" href="http://viewer.zmags.com/publication/0214a2a9?page=3"> FAE formulations can be DMF alone or a mixture of</a> <a title="EMJ Dermatol. 2020 Suppl 1 page 4" href="http://viewer.zmags.com/publication/0214a2a9?page=4"> DMF/MMF* HCA2Cell surface Cytosol Conjugation</a> <a title="EMJ Dermatol. 2020 Suppl 1 page 5" href="http://viewer.zmags.com/publication/0214a2a9?page=5"> modulate transcription factors that are sensitive</a> <a title="EMJ Dermatol. 2020 Suppl 1 page 6" href="http://viewer.zmags.com/publication/0214a2a9?page=6"> with another therapy such as phototherapy, t</a> <a title="EMJ Dermatol. 2020 Suppl 1 page 7" href="http://viewer.zmags.com/publication/0214a2a9?page=7"> Biological Treatment: Role of IL-23 </a> <a title="EMJ Dermatol. 2020 Suppl 1 page 8" href="http://viewer.zmags.com/publication/0214a2a9?page=8"> Table 1: Targets, dose, and regimen for biologic </a> <a title="EMJ Dermatol. 2020 Suppl 1 page 9" href="http://viewer.zmags.com/publication/0214a2a9?page=9"> and worsening of inflammation. Hence, in theory, u</a> <a title="EMJ Dermatol. 2020 Suppl 1 page 10" href="http://viewer.zmags.com/publication/0214a2a9?page=10"> 12. Martinon F et al. The inflammasomes: 26.</a> <a title="EMJ Dermatol. 2020 Suppl 1 page 11" href="http://viewer.zmags.com/publication/0214a2a9?page=11"> Hepatology. 2017;65(2):739-48. </a> <a title="EMJ Dermatol. 2020 Suppl 1 page 12" href="http://viewer.zmags.com/publication/0214a2a9?page=12"> New Insights into Dimethyl Fumarate, an Oral Ther</a> <a title="EMJ Dermatol. 2020 Suppl 1 page 13" href="http://viewer.zmags.com/publication/0214a2a9?page=13"> Efficacy of Dimethyl Fumarate in Clinical Practic</a> <a title="EMJ Dermatol. 2020 Suppl 1 page 14" href="http://viewer.zmags.com/publication/0214a2a9?page=14"> PASI 50 responses at Week 24, while 64.7% (OC) an</a> <a title="EMJ Dermatol. 2020 Suppl 1 page 15" href="http://viewer.zmags.com/publication/0214a2a9?page=15"> Improvement of Patient-Reported Outcomes i</a> <a title="EMJ Dermatol. 2020 Suppl 1 page 16" href="http://viewer.zmags.com/publication/0214a2a9?page=16"> 10.0 </a> <a title="EMJ Dermatol. 2020 Suppl 1 page 17" href="http://viewer.zmags.com/publication/0214a2a9?page=17"> the scale of 0–10 points (with 10 as maximum sati</a> <a title="EMJ Dermatol. 2020 Suppl 1 page 18" href="http://viewer.zmags.com/publication/0214a2a9?page=18"> of 11.2 μM for a 240 mg dose);35 a >2-fold increa</a> <a title="EMJ Dermatol. 2020 Suppl 1 page 19" href="http://viewer.zmags.com/publication/0214a2a9?page=19"> References 1. Carrascosa JM et al. Efficacy </a>