If you are visually impaired or blind, you can visit the PDF version by Pressing CONTROL + ALT + 4
<br /> ARCHIVE<br /> VOLUME 111 NUMBER 1 JANUARY 2016<br /> www.nature.com/ajg<br /> official publication of the american college of gastroenterology<br /> LEADING ARTICLES OF THE MONTH<br /> The Red Section: EndoTech Update<br /> 6 Just Clip It: Endoscopic Clipping in the 21st Century<br /> B. Joseph Elmunzer<br /> Practice Guidelines<br /> 30 ACG Clinical Guideline: Diagnosis and Management of Barrett’s<br /> Esophagus CME<br /> N.J. Shaheen, G.W. Falk, P.G. Iyer and L.B. Gerson<br /> Clinical and Systematic Reviews<br /> 53 Diagnosis and Management of Functional Heartburn CME<br /> C. Hachem and N.J. Shaheen<br /> Endoscopy<br /> 63 Effect of Dynamic Position Changes on Adenoma Detection during<br /> Colonoscope Withdrawal: A Randomized Controlled Multicenter Trial<br /> S.-W. Lee, J.H. Chang, J.-S. Ji et al.<br /> Liver<br /> 78 Diagnosis of Minima<a title="AJG_Vol.111.No.10 page 1" href="http://viewer.zmags.com/publication/079ad02d?page=1"> ARCHIVE VOLUME 111 NUMBER 1 JANUARY 2016 www.nat</a> <a title="AJG_Vol.111.No.10 page 2" href="http://viewer.zmags.com/publication/079ad02d?page=2"> VOLUME 111 NUMBER 10 OCTOBER 2016 www.nature.co</a> <a title="AJG_Vol.111.No.10 page 3" href="http://viewer.zmags.com/publication/079ad02d?page=3"> Treat IBS-Di erently A 2-week treatment for IBS-</a> <a title="AJG_Vol.111.No.10 page 4" href="http://viewer.zmags.com/publication/079ad02d?page=4"> BRIEF SUMMARY OF PRESCRIBING INFORMATION This Bri</a> <a title="AJG_Vol.111.No.10 page 5" href="http://viewer.zmags.com/publication/079ad02d?page=5"> www.nature.com/ajg The American Journal o</a> <a title="AJG_Vol.111.No.10 page 6" href="http://viewer.zmags.com/publication/079ad02d?page=6"> Patients of any HCV genotype can now be cured wit</a> <a title="AJG_Vol.111.No.10 page 7" href="http://viewer.zmags.com/publication/079ad02d?page=7"> Albert Einstein used with permission of the HUJ/G</a> <a title="AJG_Vol.111.No.10 page 8" href="http://viewer.zmags.com/publication/079ad02d?page=8"> NOW APPROVED THE FIRST AND ONLY PAN-GENOTYPIC ONC</a> <a title="AJG_Vol.111.No.10 page 9" href="http://viewer.zmags.com/publication/079ad02d?page=9"> HARVONI® (ledipasvir 90 mg and sofosbuvir 400 mg)</a> <a title="AJG_Vol.111.No.10 page 10" href="http://viewer.zmags.com/publication/079ad02d?page=10"> Brief Summary (cont.) Postmarketing Experience: B</a> <a title="AJG_Vol.111.No.10 page 11" href="http://viewer.zmags.com/publication/079ad02d?page=11"> EPCLUSA® (sofosbuvir 400 mg and velpatasvir 100 m</a> <a title="AJG_Vol.111.No.10 page 12" href="http://viewer.zmags.com/publication/079ad02d?page=12"> Brief Summary (cont.) DRUG INTERACTIONS: Sofosbuv</a> <a title="AJG_Vol.111.No.10 page 13" href="http://viewer.zmags.com/publication/079ad02d?page=13"> official publication of the american college</a> <a title="AJG_Vol.111.No.10 page 14" href="http://viewer.zmags.com/publication/079ad02d?page=14"> FOR PATIENTS WITH ACTIVE, MILD TO MODERATE ULCERA</a> <a title="AJG_Vol.111.No.10 page 15" href="http://viewer.zmags.com/publication/079ad02d?page=15"> BRIEF SUMMARY OF PRESCRIBING INFORMATION This bri</a> <a title="AJG_Vol.111.No.10 page 16" href="http://viewer.zmags.com/publication/079ad02d?page=16"> THE #1 MOST PRESCRIBED, BRANDED BOWEL PREP KIT1 </a> <a title="AJG_Vol.111.No.10 page 17" href="http://viewer.zmags.com/publication/079ad02d?page=17"> IMPORTANT SAFETY INFORMATION SUPREP® Bowel Prep K</a> <a title="AJG_Vol.111.No.10 page 18" href="http://viewer.zmags.com/publication/079ad02d?page=18"> Less time More time infusing.* </a> <a title="AJG_Vol.111.No.10 page 19" href="http://viewer.zmags.com/publication/079ad02d?page=19"> BRIEF SUMMARY OF PRESCRIBING INFORMATION </a> <a title="AJG_Vol.111.No.10 page 20" href="http://viewer.zmags.com/publication/079ad02d?page=20"> PROVIDING ACHALASIA PATIENTS WITH OPTIONS INSTEAD</a> <a title="AJG_Vol.111.No.10 page 21" href="http://viewer.zmags.com/publication/079ad02d?page=21"> RECOMMEND THE MOST POWERFUL OTC PPI FROM THE STAR</a> <a title="AJG_Vol.111.No.10 page 22" href="http://viewer.zmags.com/publication/079ad02d?page=22"> COMING SOON Visit zinplava.com to register and r</a> <a title="AJG_Vol.111.No.10 page 23" href="http://viewer.zmags.com/publication/079ad02d?page=23"> INDICATION AND IMPORTANT SAFETY INFORMATION FOR H</a> <a title="AJG_Vol.111.No.10 page 24" href="http://viewer.zmags.com/publication/079ad02d?page=24"> MODERATE TO SEVERE CROHN'S DISEASE (CD) My </a> <a title="AJG_Vol.111.No.10 page 25" href="http://viewer.zmags.com/publication/079ad02d?page=25"> HUMIRA® (adalimumab) </a> <a title="AJG_Vol.111.No.10 page 26" href="http://viewer.zmags.com/publication/079ad02d?page=26"> Autoimmunity Treatment with HUMIRA may result in </a> <a title="AJG_Vol.111.No.10 page 27" href="http://viewer.zmags.com/publication/079ad02d?page=27"> Hidradenitis Suppurativa Clinical Studies HUMIRA </a> <a title="AJG_Vol.111.No.10 page 28" href="http://viewer.zmags.com/publication/079ad02d?page=28"> 65 Years of GI Endoscopy Innovation in One Powerf</a> <a title="AJG_Vol.111.No.10 page 29" href="http://viewer.zmags.com/publication/079ad02d?page=29"> Another Miracle? No, it's MiraFIBER™ </a> <a title="AJG_Vol.111.No.10 page 30" href="http://viewer.zmags.com/publication/079ad02d?page=30"> Colonoscopy in a 70-year-old man with remote hist</a> <a title="AJG_Vol.111.No.10 page 31" href="http://viewer.zmags.com/publication/079ad02d?page=31"> CONTENTS a 18 16 14 UES discomfort threshol</a> <a title="AJG_Vol.111.No.10 page 32" href="http://viewer.zmags.com/publication/079ad02d?page=32"> www.nature.com/ajg VNTR3/VNTR</a> <a title="AJG_Vol.111.No.10 page 33" href="http://viewer.zmags.com/publication/079ad02d?page=33"> Help Patients Reach 20 to 35 Grams </a> <a title="AJG_Vol.111.No.10 page 34" href="http://viewer.zmags.com/publication/079ad02d?page=34"> * *by patients in clinical trials† In </a> <a title="AJG_Vol.111.No.10 page 35" href="http://viewer.zmags.com/publication/079ad02d?page=35"> The following is a brief summary only; see full P</a> <a title="AJG_Vol.111.No.10 page 36" href="http://viewer.zmags.com/publication/079ad02d?page=36"> YOUR LAB EQUIPMENT RESOURCE nature.com/marketplac</a> <a title="AJG_Vol.111.No.10 page 37" href="http://viewer.zmags.com/publication/079ad02d?page=37"> Come visit us at ACG Booth 1102 I N T R O D</a> <a title="AJG_Vol.111.No.10 page 38" href="http://viewer.zmags.com/publication/079ad02d?page=38"> The first NEW treatment for PBC in nearly 20 years</a> <a title="AJG_Vol.111.No.10 page 39" href="http://viewer.zmags.com/publication/079ad02d?page=39"> Delivered Significant, Sustained Reductions </a> <a title="AJG_Vol.111.No.10 page 40" href="http://viewer.zmags.com/publication/079ad02d?page=40"> New, for patients with PBC who have had an inadeq</a> <a title="AJG_Vol.111.No.10 page 41" href="http://viewer.zmags.com/publication/079ad02d?page=41"> Brief Summary of Prescribing Information for OCAL</a> <a title="AJG_Vol.111.No.10 page 42" href="http://viewer.zmags.com/publication/079ad02d?page=42"> [see Clinical Pharmacology (12.3) in Full Prescri</a> <a title="AJG_Vol.111.No.10 page 43" href="http://viewer.zmags.com/publication/079ad02d?page=43"> APPLY for an ACG Institute Research Award Dea</a> <a title="AJG_Vol.111.No.10 page 44" href="http://viewer.zmags.com/publication/079ad02d?page=44"> ACHIEVE MORE WITH EUS ACQUIRE CONFIDEN</a> <a title="AJG_Vol.111.No.10 page 45" href="http://viewer.zmags.com/publication/079ad02d?page=45"> 2017 ACG EASTERN REGIONAL POSTGRADUATE COURSE </a> <a title="AJG_Vol.111.No.10 page 46" href="http://viewer.zmags.com/publication/079ad02d?page=46"> WHAT ARE BIOSIMILARS? Let’s Clarify Biosimilar</a> <a title="AJG_Vol.111.No.10 page 47" href="http://viewer.zmags.com/publication/079ad02d?page=47"> GI QUALITY IMPROVEMENT CONSORTIUM LTD 3 Se ing</a> <a title="AJG_Vol.111.No.10 page 48" href="http://viewer.zmags.com/publication/079ad02d?page=48"> Don't your patients deserve to know what you alre</a> <a title="AJG_Vol.111.No.10 page 49" href="http://viewer.zmags.com/publication/079ad02d?page=49"> Committed to you and your patients. </a> <a title="AJG_Vol.111.No.10 page 50" href="http://viewer.zmags.com/publication/079ad02d?page=50"> Proud to bring you these products.</a> <a title="AJG_Vol.111.No.10 page 51" href="http://viewer.zmags.com/publication/079ad02d?page=51"> BRIEF SUMMARY: Consult the Full Prescribing Infor</a> <a title="AJG_Vol.111.No.10 page 52" href="http://viewer.zmags.com/publication/079ad02d?page=52"> not always possible to reliably estimate their fr</a> <a title="AJG_Vol.111.No.10 page 53" href="http://viewer.zmags.com/publication/079ad02d?page=53"> A key thread in your scientific career Whether in</a> <a title="AJG_Vol.111.No.10 page 54" href="http://viewer.zmags.com/publication/079ad02d?page=54"> BRIEF SUMMARY OF PRESCRIBING INFORMATION This Br</a> <a title="AJG_Vol.111.No.10 page 55" href="http://viewer.zmags.com/publication/079ad02d?page=55"> Hepatic Encephalopathy (HE) CAUSES EPISODIC NEURO</a> <a title="AJG_Vol.111.No.10 page 56" href="http://viewer.zmags.com/publication/079ad02d?page=56"> THE RED SECTION 1371 see related edito</a> <a title="AJG_Vol.111.No.10 page 57" href="http://viewer.zmags.com/publication/079ad02d?page=57"> 1372 THE RED SECTION </a> <a title="AJG_Vol.111.No.10 page 58" href="http://viewer.zmags.com/publication/079ad02d?page=58"> Figure 3. Comparative images from conventional en</a> <a title="AJG_Vol.111.No.10 page 59" href="http://viewer.zmags.com/publication/079ad02d?page=59"> 1374 THE RED SECTION </a> <a title="AJG_Vol.111.No.10 page 60" href="http://viewer.zmags.com/publication/079ad02d?page=60"> THE RED SECTION 1375 Figur</a> <a title="AJG_Vol.111.No.10 page 61" href="http://viewer.zmags.com/publication/079ad02d?page=61"> 1376 THE RED SECTION </a> <a title="AJG_Vol.111.No.10 page 62" href="http://viewer.zmags.com/publication/079ad02d?page=62"> · Corporations must provide to DOJ all relevan</a> <a title="AJG_Vol.111.No.10 page 63" href="http://viewer.zmags.com/publication/079ad02d?page=63"> 1378 THE RED SECTION Images of the Mo</a> <a title="AJG_Vol.111.No.10 page 64" href="http://viewer.zmags.com/publication/079ad02d?page=64"> THE RED SECTION 1379 Palliative Decompr</a> <a title="AJG_Vol.111.No.10 page 65" href="http://viewer.zmags.com/publication/079ad02d?page=65"> 1380 THE RED SECTION Gastric Mucosal Calc</a> <a title="AJG_Vol.111.No.10 page 66" href="http://viewer.zmags.com/publication/079ad02d?page=66"> THE RED SECTION 1381 Video of the Month En</a> <a title="AJG_Vol.111.No.10 page 67" href="http://viewer.zmags.com/publication/079ad02d?page=67"> 1382 ORIGINAL CONTRIBUTIONS ESOPHAGUS INTRODUC</a> <a title="AJG_Vol.111.No.10 page 68" href="http://viewer.zmags.com/publication/079ad02d?page=68"> (UES) motor function including UES resting pressu</a> <a title="AJG_Vol.111.No.10 page 69" href="http://viewer.zmags.com/publication/079ad02d?page=69"> 1384 Rommel et al. ESOPHAGUS UES deglutiti</a> <a title="AJG_Vol.111.No.10 page 70" href="http://viewer.zmags.com/publication/079ad02d?page=70"> Table 1. Clinical data of globus patients and hea</a> <a title="AJG_Vol.111.No.10 page 71" href="http://viewer.zmags.com/publication/079ad02d?page=71"> 1386 Rommel et al. ESOPHAGUS Table 2. Biva</a> <a title="AJG_Vol.111.No.10 page 72" href="http://viewer.zmags.com/publication/079ad02d?page=72"> not included as a motility parameter, as it is hi</a> <a title="AJG_Vol.111.No.10 page 73" href="http://viewer.zmags.com/publication/079ad02d?page=73"> 1388 Rommel et al. ESOPHAGUS 7. Flores TC</a> <a title="AJG_Vol.111.No.10 page 74" href="http://viewer.zmags.com/publication/079ad02d?page=74"> ORIGINAL CONTRIBUTIONS 1389 see related</a> <a title="AJG_Vol.111.No.10 page 75" href="http://viewer.zmags.com/publication/079ad02d?page=75"> 1390 Lu et al. ENDOSCOPY practice. Some ha</a> <a title="AJG_Vol.111.No.10 page 76" href="http://viewer.zmags.com/publication/079ad02d?page=76"> Budget Impact Analysis of PPIs 1391 Inj</a> <a title="AJG_Vol.111.No.10 page 77" href="http://viewer.zmags.com/publication/079ad02d?page=77"> 1392 Lu et al. ENDOSCOPY Table 1. Base-cas</a> <a title="AJG_Vol.111.No.10 page 78" href="http://viewer.zmags.com/publication/079ad02d?page=78"> Budget Impact Analysis of PPIs 1393 Tabl</a> <a title="AJG_Vol.111.No.10 page 79" href="http://viewer.zmags.com/publication/079ad02d?page=79"> 1394 Lu et al. ENDOSCOPY Table 2. Cost est</a> <a title="AJG_Vol.111.No.10 page 80" href="http://viewer.zmags.com/publication/079ad02d?page=80"> Table 3. Total cost per patient and cost differen</a> <a title="AJG_Vol.111.No.10 page 81" href="http://viewer.zmags.com/publication/079ad02d?page=81"> 1396 Lu et al. ENDOSCOPY Variables markers </a> <a title="AJG_Vol.111.No.10 page 82" href="http://viewer.zmags.com/publication/079ad02d?page=82"> 1.68% of total costs per patient admitted with NV</a> <a title="AJG_Vol.111.No.10 page 83" href="http://viewer.zmags.com/publication/079ad02d?page=83"> 1398 Lu et al. ENDOSCOPY REFERENCES 1. Le</a> <a title="AJG_Vol.111.No.10 page 84" href="http://viewer.zmags.com/publication/079ad02d?page=84"> EDITORIAL 1399 see related article on </a> <a title="AJG_Vol.111.No.10 page 85" href="http://viewer.zmags.com/publication/079ad02d?page=85"> 1400 Peterson and Bjorkman ENDOSCOPY The r</a> <a title="AJG_Vol.111.No.10 page 86" href="http://viewer.zmags.com/publication/079ad02d?page=86"> Editorial 1401 14. Jian Z, Li H, Race N</a> <a title="AJG_Vol.111.No.10 page 87" href="http://viewer.zmags.com/publication/079ad02d?page=87"> 1402 ORIGINAL CONTRIBUTIONS LIVER see related</a> <a title="AJG_Vol.111.No.10 page 88" href="http://viewer.zmags.com/publication/079ad02d?page=88"> INTRODUCTION Bacterial infections are a common ca</a> <a title="AJG_Vol.111.No.10 page 89" href="http://viewer.zmags.com/publication/079ad02d?page=89"> 1404 Thévenot et al. LIVER “Trace”, “Small</a> <a title="AJG_Vol.111.No.10 page 90" href="http://viewer.zmags.com/publication/079ad02d?page=90"> Periscreen Strip and Spontaneous Bacterial Perito</a> <a title="AJG_Vol.111.No.10 page 91" href="http://viewer.zmags.com/publication/079ad02d?page=91"> 1406 Thévenot et al. LIVER Table 3. Diagno</a> <a title="AJG_Vol.111.No.10 page 92" href="http://viewer.zmags.com/publication/079ad02d?page=92"> who have a lower risk of SBP (3.5% or lower (23–2</a> <a title="AJG_Vol.111.No.10 page 93" href="http://viewer.zmags.com/publication/079ad02d?page=93"> 1408 Thévenot et al. LIVER ACKNOWLEDGMENTS</a> <a title="AJG_Vol.111.No.10 page 94" href="http://viewer.zmags.com/publication/079ad02d?page=94"> 26. Guarner C, Solà R, Soriano G et al. Risk of a</a> <a title="AJG_Vol.111.No.10 page 95" href="http://viewer.zmags.com/publication/079ad02d?page=95"> 1410 ORIGINAL CONTRIBUTIONS see relate</a> <a title="AJG_Vol.111.No.10 page 96" href="http://viewer.zmags.com/publication/079ad02d?page=96"> during pregnancy (11–14), and several studies hav</a> <a title="AJG_Vol.111.No.10 page 97" href="http://viewer.zmags.com/publication/079ad02d?page=97"> 1412 Chang et al. LIVER Table 1. Baseline </a> <a title="AJG_Vol.111.No.10 page 98" href="http://viewer.zmags.com/publication/079ad02d?page=98"> Flares in Pregnant and Postpartum CHB Women 1</a> <a title="AJG_Vol.111.No.10 page 99" href="http://viewer.zmags.com/publication/079ad02d?page=99"> 25 94.3* 53* 1414 Chang et al. 6 </a> <a title="AJG_Vol.111.No.10 page 100" href="http://viewer.zmags.com/publication/079ad02d?page=100"> advisory board of Gilead Sciences, Bristol-Myers </a> <a title="AJG_Vol.111.No.10 page 101" href="http://viewer.zmags.com/publication/079ad02d?page=101"> 1416 ORIGINAL CONTRIBUTIONS INFLAMMATORY BOWEL</a> <a title="AJG_Vol.111.No.10 page 102" href="http://viewer.zmags.com/publication/079ad02d?page=102"> some studies, although a recent meta-analysis fou</a> <a title="AJG_Vol.111.No.10 page 103" href="http://viewer.zmags.com/publication/079ad02d?page=103"> 1418 Ungaro et al. INFLAMMATORY BOWEL DISEA</a> <a title="AJG_Vol.111.No.10 page 104" href="http://viewer.zmags.com/publication/079ad02d?page=104"> Statins and Risk of New Onset Inflammatory Bowel </a> <a title="AJG_Vol.111.No.10 page 105" href="http://viewer.zmags.com/publication/079ad02d?page=105"> 1420 Ungaro et al. INFLAMMATORY BOWEL DISEA</a> <a title="AJG_Vol.111.No.10 page 106" href="http://viewer.zmags.com/publication/079ad02d?page=106"> Table 5. OR for IBD, CD, and UC with any statin e</a> <a title="AJG_Vol.111.No.10 page 107" href="http://viewer.zmags.com/publication/079ad02d?page=107"> 1422 Ungaro et al. INFLAMMATORY BOWEL DISEA</a> <a title="AJG_Vol.111.No.10 page 108" href="http://viewer.zmags.com/publication/079ad02d?page=108"> 30. Targownik LE, Suissa S. Understanding and avo</a> <a title="AJG_Vol.111.No.10 page 109" href="http://viewer.zmags.com/publication/079ad02d?page=109"> 1424 EDITORIAL see related article on </a> <a title="AJG_Vol.111.No.10 page 110" href="http://viewer.zmags.com/publication/079ad02d?page=110"> compliance and discontinuation owing to side effe</a> <a title="AJG_Vol.111.No.10 page 111" href="http://viewer.zmags.com/publication/079ad02d?page=111"> 1426 Khalili INFLAMMATORY BOWEL DISEASE 13</a> <a title="AJG_Vol.111.No.10 page 112" href="http://viewer.zmags.com/publication/079ad02d?page=112"> ORIGINAL CONTRIBUTIONS 1427 CME Con</a> <a title="AJG_Vol.111.No.10 page 113" href="http://viewer.zmags.com/publication/079ad02d?page=113"> 1428 ORIGINAL CONTRIBUTIONS sCeMeErela</a> <a title="AJG_Vol.111.No.10 page 114" href="http://viewer.zmags.com/publication/079ad02d?page=114"> INTRODUCTION Inflammatory bowel disease (IBD) inc</a> <a title="AJG_Vol.111.No.10 page 115" href="http://viewer.zmags.com/publication/079ad02d?page=115"> 1430 Cheddani et al. INFLAMMATORY BOWEL DIS</a> <a title="AJG_Vol.111.No.10 page 116" href="http://viewer.zmags.com/publication/079ad02d?page=116"> Cancer in Elderly Onset Inflammatory Bowel Diseas</a> <a title="AJG_Vol.111.No.10 page 117" href="http://viewer.zmags.com/publication/079ad02d?page=117"> 1432 Cheddani et al. INFLAMMATORY BOWEL DIS</a> <a title="AJG_Vol.111.No.10 page 118" href="http://viewer.zmags.com/publication/079ad02d?page=118"> Table 4. Observed and expected number of cancer i</a> <a title="AJG_Vol.111.No.10 page 119" href="http://viewer.zmags.com/publication/079ad02d?page=119"> 1434 Cheddani et al. INFLAMMATORY BOWEL DIS</a> <a title="AJG_Vol.111.No.10 page 120" href="http://viewer.zmags.com/publication/079ad02d?page=120"> (INSERM) and the Institut de Veille Sanitaire (In</a> <a title="AJG_Vol.111.No.10 page 121" href="http://viewer.zmags.com/publication/079ad02d?page=121"> 1436 Cheddani et al. INFLAMMATORY BOWEL DIS</a> <a title="AJG_Vol.111.No.10 page 122" href="http://viewer.zmags.com/publication/079ad02d?page=122"> ORIGINAL CONTRIBUTIONS 1437 CME Con</a> <a title="AJG_Vol.111.No.10 page 123" href="http://viewer.zmags.com/publication/079ad02d?page=123"> 1438 ORIGINAL CONTRIBUTIONS sCeMeErela</a> <a title="AJG_Vol.111.No.10 page 124" href="http://viewer.zmags.com/publication/079ad02d?page=124"> ACT-1, and ACT-2 demonstrated that IFX concentrat</a> <a title="AJG_Vol.111.No.10 page 125" href="http://viewer.zmags.com/publication/079ad02d?page=125"> 1440 Billiet et al. INFLAMMATORY BOWEL DISE</a> <a title="AJG_Vol.111.No.10 page 126" href="http://viewer.zmags.com/publication/079ad02d?page=126"> Table 1. Patients characteristics at baseline Bas</a> <a title="AJG_Vol.111.No.10 page 127" href="http://viewer.zmags.com/publication/079ad02d?page=127"> 1442 Billiet et al. UC diagnosis -113.1 (18</a> <a title="AJG_Vol.111.No.10 page 128" href="http://viewer.zmags.com/publication/079ad02d?page=128"> a 3,000 .d/ml 2,000 AUCIFX µg 1,000 0 Q1 (</a> <a title="AJG_Vol.111.No.10 page 129" href="http://viewer.zmags.com/publication/079ad02d?page=129"> 1444 Billiet et al. INFLAMMATORY BOWEL DISE</a> <a title="AJG_Vol.111.No.10 page 130" href="http://viewer.zmags.com/publication/079ad02d?page=130"> Ann Gils; study supervision and critical revision</a> <a title="AJG_Vol.111.No.10 page 131" href="http://viewer.zmags.com/publication/079ad02d?page=131"> 1446 ORIGINAL CONTRIBUTIONS FUNCTIONAL GI DISO</a> <a title="AJG_Vol.111.No.10 page 132" href="http://viewer.zmags.com/publication/079ad02d?page=132"> symptoms and those of IBS can mimic organic disea</a> <a title="AJG_Vol.111.No.10 page 133" href="http://viewer.zmags.com/publication/079ad02d?page=133"> 1448 Sood et al. Table 1. Findings consi</a> <a title="AJG_Vol.111.No.10 page 134" href="http://viewer.zmags.com/publication/079ad02d?page=134"> RESULTS There were 1,002 consecutive patients (me</a> <a title="AJG_Vol.111.No.10 page 135" href="http://viewer.zmags.com/publication/079ad02d?page=135"> 1450 Sood et al. FUNCTIONAL GI DISORDERS T</a> <a title="AJG_Vol.111.No.10 page 136" href="http://viewer.zmags.com/publication/079ad02d?page=136"> Enhancing Clinical Diagnosis of IBS 1451 </a> <a title="AJG_Vol.111.No.10 page 137" href="http://viewer.zmags.com/publication/079ad02d?page=137"> 1452 Sood et al. GI DISORDERS FUNCTIONAL T</a> <a title="AJG_Vol.111.No.10 page 138" href="http://viewer.zmags.com/publication/079ad02d?page=138"> Second, it was designed to adhere to the STARD gu</a> <a title="AJG_Vol.111.No.10 page 139" href="http://viewer.zmags.com/publication/079ad02d?page=139"> 1454 Sood et al. FUNCTIONAL GI DISORDERS 8</a> <a title="AJG_Vol.111.No.10 page 140" href="http://viewer.zmags.com/publication/079ad02d?page=140"> ORIGINAL CONTRIBUTIONS 1455 CME Con</a> <a title="AJG_Vol.111.No.10 page 141" href="http://viewer.zmags.com/publication/079ad02d?page=141"> 1456 ORIGINAL CONTRIBUTIONS COLON/SMALL BOWEL </a> <a title="AJG_Vol.111.No.10 page 142" href="http://viewer.zmags.com/publication/079ad02d?page=142"> INTRODUCTION Celiac disease (CD) is an immun</a> <a title="AJG_Vol.111.No.10 page 143" href="http://viewer.zmags.com/publication/079ad02d?page=143"> 1458 Comino et al. COLON/SMALL BOWEL the </a> <a title="AJG_Vol.111.No.10 page 144" href="http://viewer.zmags.com/publication/079ad02d?page=144"> Table 1. Characteristics of patients enrolled in </a> <a title="AJG_Vol.111.No.10 page 145" href="http://viewer.zmags.com/publication/079ad02d?page=145"> Negative controls Positive controls </a> <a title="AJG_Vol.111.No.10 page 146" href="http://viewer.zmags.com/publication/079ad02d?page=146"> percentages of GIP-positive stools. Patients on t</a> <a title="AJG_Vol.111.No.10 page 147" href="http://viewer.zmags.com/publication/079ad02d?page=147"> 1462 Comino et al. a 100 </a> <a title="AJG_Vol.111.No.10 page 148" href="http://viewer.zmags.com/publication/079ad02d?page=148"> in asymptomatic patients), small bowel biopsy is </a> <a title="AJG_Vol.111.No.10 page 149" href="http://viewer.zmags.com/publication/079ad02d?page=149"> 1464 Comino et al. COLON/SMALL BOWEL Study</a> <a title="AJG_Vol.111.No.10 page 150" href="http://viewer.zmags.com/publication/079ad02d?page=150"> 32. Dickey W, Hughes DF, McMillan SA. Patients wi</a> <a title="AJG_Vol.111.No.10 page 151" href="http://viewer.zmags.com/publication/079ad02d?page=151"> 1466 ORIGINAL CONTRIBUTIONS CME COLON</a> <a title="AJG_Vol.111.No.10 page 152" href="http://viewer.zmags.com/publication/079ad02d?page=152"> ORIGINAL CONTRIBUTIONS 1467 sCeMeErela</a> <a title="AJG_Vol.111.No.10 page 153" href="http://viewer.zmags.com/publication/079ad02d?page=153"> 1468 JØrgensen et al. COLON/SMALL BOWEL IN</a> <a title="AJG_Vol.111.No.10 page 154" href="http://viewer.zmags.com/publication/079ad02d?page=154"> most recent European (16) and the American </a> <a title="AJG_Vol.111.No.10 page 155" href="http://viewer.zmags.com/publication/079ad02d?page=155"> 1470 JØrgensen et al. COLON/SMALL BOWEL Ta</a> <a title="AJG_Vol.111.No.10 page 156" href="http://viewer.zmags.com/publication/079ad02d?page=156"> Gastrointestinal Disease in CVID 1471 COLON/</a> <a title="AJG_Vol.111.No.10 page 157" href="http://viewer.zmags.com/publication/079ad02d?page=157"> 1472 JØrgensen et al. COLON/SMALL BOWEL IE</a> <a title="AJG_Vol.111.No.10 page 158" href="http://viewer.zmags.com/publication/079ad02d?page=158"> stomach and duodenum), and one positive in the co</a> <a title="AJG_Vol.111.No.10 page 159" href="http://viewer.zmags.com/publication/079ad02d?page=159"> 1474 JØrgensen et al. COLON/SMALL BOWEL pa</a> <a title="AJG_Vol.111.No.10 page 160" href="http://viewer.zmags.com/publication/079ad02d?page=160"> 2. Resnick ES, Moshier EL, Godbold JH et al. Mor</a> <a title="AJG_Vol.111.No.10 page 161" href="http://viewer.zmags.com/publication/079ad02d?page=161"> 1476 ORIGINAL CONTRIBUTIONS PANCREAS AND BILIA</a> <a title="AJG_Vol.111.No.10 page 162" href="http://viewer.zmags.com/publication/079ad02d?page=162"> raphy-based epidemiological studies have repo</a> <a title="AJG_Vol.111.No.10 page 163" href="http://viewer.zmags.com/publication/079ad02d?page=163"> 1478 Ryu et al. PANCREAS AND BILIARY TRACT </a> <a title="AJG_Vol.111.No.10 page 164" href="http://viewer.zmags.com/publication/079ad02d?page=164"> Gallstone Disease and Gallbladder Cancer Mortalit</a> <a title="AJG_Vol.111.No.10 page 165" href="http://viewer.zmags.com/publication/079ad02d?page=165"> 1480 Ryu et al. PANCREAS AND BILIARY TRACT </a> <a title="AJG_Vol.111.No.10 page 166" href="http://viewer.zmags.com/publication/079ad02d?page=166"> cancer. In fact, it is difficult to firmly conclu</a> <a title="AJG_Vol.111.No.10 page 167" href="http://viewer.zmags.com/publication/079ad02d?page=167"> 1482 Ryu et al. PANCREAS AND BILIARY TRACT </a> <a title="AJG_Vol.111.No.10 page 168" href="http://viewer.zmags.com/publication/079ad02d?page=168"> Gallstone Disease and Gallbladder Cancer Mortalit</a> <a title="AJG_Vol.111.No.10 page 169" href="http://viewer.zmags.com/publication/079ad02d?page=169"> 1484 Ryu et al. APPENDIX TABLE 2 PANC</a> <a title="AJG_Vol.111.No.10 page 170" href="http://viewer.zmags.com/publication/079ad02d?page=170"> Gallstone Disease and Gallbladder Cancer Mortalit</a> <a title="AJG_Vol.111.No.10 page 171" href="http://viewer.zmags.com/publication/079ad02d?page=171"> 1486 Ryu et al. APPENDIX TABLE 4 PANC</a> <a title="AJG_Vol.111.No.10 page 172" href="http://viewer.zmags.com/publication/079ad02d?page=172"> Gallstone Disease and Gallbladder Cancer Mortalit</a> <a title="AJG_Vol.111.No.10 page 173" href="http://viewer.zmags.com/publication/079ad02d?page=173"> 1488 ORIGINAL CONTRIBUTIONS see relate</a> <a title="AJG_Vol.111.No.10 page 174" href="http://viewer.zmags.com/publication/079ad02d?page=174"> INTRODUCTION Chronic pancreatitis (CP) is a chron</a> <a title="AJG_Vol.111.No.10 page 175" href="http://viewer.zmags.com/publication/079ad02d?page=175"> 1490 Wilcox et al. five predefined cat</a> <a title="AJG_Vol.111.No.10 page 176" href="http://viewer.zmags.com/publication/079ad02d?page=176"> Table 1. Demographics by race among subjects with</a> <a title="AJG_Vol.111.No.10 page 177" href="http://viewer.zmags.com/publication/079ad02d?page=177"> 1492 Wilcox et al. PANCREAS AND BILIARY TRA</a> <a title="AJG_Vol.111.No.10 page 178" href="http://viewer.zmags.com/publication/079ad02d?page=178"> Race and Chronic Pancreatitis 1493 Table </a> <a title="AJG_Vol.111.No.10 page 179" href="http://viewer.zmags.com/publication/079ad02d?page=179"> 1494 Wilcox et al. PANCREAS AND BILIARY TRA</a> <a title="AJG_Vol.111.No.10 page 180" href="http://viewer.zmags.com/publication/079ad02d?page=180"> mislocalization results in formation of pancreati</a> <a title="AJG_Vol.111.No.10 page 181" href="http://viewer.zmags.com/publication/079ad02d?page=181"> 1496 Wilcox et al. PANCREAS AND BILIARY TRA</a> <a title="AJG_Vol.111.No.10 page 182" href="http://viewer.zmags.com/publication/079ad02d?page=182"> LETTERS TO THE EDITOR 1497 Levofloxac</a> <a title="AJG_Vol.111.No.10 page 183" href="http://viewer.zmags.com/publication/079ad02d?page=183"> 1498 Letters to the Editor therapy was </a> <a title="AJG_Vol.111.No.10 page 184" href="http://viewer.zmags.com/publication/079ad02d?page=184"> disorders http://www.romecriteria.org/cr</a> <a title="AJG_Vol.111.No.10 page 185" href="http://viewer.zmags.com/publication/079ad02d?page=185"> 1500 Letters to the Editor symptoms. Mo</a> <a title="AJG_Vol.111.No.10 page 186" href="http://viewer.zmags.com/publication/079ad02d?page=186"> would be undoubtedly a cost-effective and drug-sp</a> <a title="AJG_Vol.111.No.10 page 187" href="http://viewer.zmags.com/publication/079ad02d?page=187"> 1502 Letters to the Editor with ureter</a> <a title="AJG_Vol.111.No.10 page 188" href="http://viewer.zmags.com/publication/079ad02d?page=188"> ANNOUNCEMENTS 1503 CALENDAR OF COURS</a> <a title="AJG_Vol.111.No.10 page 189" href="http://viewer.zmags.com/publication/079ad02d?page=189"> 1504 ERRATA, CORRIGENDA AND RETRACTIONS CORRI</a> <a title="AJG_Vol.111.No.10 page 190" href="http://viewer.zmags.com/publication/079ad02d?page=190"> CLASSIFIEDS At St. Vincent Healthcare, we are</a> <a title="AJG_Vol.111.No.10 page 191" href="http://viewer.zmags.com/publication/079ad02d?page=191"> The University of Arkansas for Medical Sciences' </a> <a title="AJG_Vol.111.No.10 page 192" href="http://viewer.zmags.com/publication/079ad02d?page=192"> Dr Jacobs Treating GERD sufferers for 18 years </a> <a title="AJG_Vol.111.No.10 page 193" href="http://viewer.zmags.com/publication/079ad02d?page=193"> Adding painless, non-surgical hemorrhoid </a>