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<br /> ARCHIVE<br /> VOLUME 110 NUMBER 1 JANUARY 2015<br /> www.amjgastro.com<br /> OFFICIAL PUBLICATION OF THE AMERICAN COLLEGE OF GASTROENTEROLOGY<br /> LEADING ARTICLES OF THE MONTH<br /> Practice Guidelines<br /> 18 ACG Clinical Guidelines: Epidemiology, Risk Factors,<br /> Patterns of Presentation, Diagnosis, and Management<br /> of Colon Ischemia (CI) CME<br /> L.J. Brandt, P. Feuerstadt, G.F. Longstreth and S.J. Boley<br /> Quality Indicators for GI Endoscopic Procedures<br /> 60 Quality Indicators for EGD<br /> W.G. Park, N.J. Shaheen, J. Cohen, I.M. Pike, D.G. Adler, J.M. Inadomi,<br /> L.A. Laine, J.G. Lieb II, M.K. Rizk, M.S. Sawhney and S. Wani<br /> 72 Quality Indicators for Colonoscopy<br /> D.K. Rex, P.S. Schoenfeld, J. Cohen, I.M. Pike, D.G. Adler, M.B. Fennerty,<br /> J.G. Lieb II, W.G. Park, M.K. Rizk, M.S. Sawhney, N.J. Shaheen, S.<a title="AJG_Vol.110.No.7 page 1" href="http://viewer.zmags.com/publication/0f57c12d?page=1"> ARCHIVE VOLUME 110 NUMBER 1 JANUARY 2015 www.am</a> <a title="AJG_Vol.110.No.7 page 2" href="http://viewer.zmags.com/publication/0f57c12d?page=2"> VOLUME 110 NUMBER 7 JULY 2015 www.nature.com/aj</a> <a title="AJG_Vol.110.No.7 page 3" href="http://viewer.zmags.com/publication/0f57c12d?page=3"> * *by patients in clinical trials† </a> <a title="AJG_Vol.110.No.7 page 4" href="http://viewer.zmags.com/publication/0f57c12d?page=4"> Split-dose Prepopik demonstrated‡: EFFE</a> <a title="AJG_Vol.110.No.7 page 5" href="http://viewer.zmags.com/publication/0f57c12d?page=5"> The following is a brief summary only; see full P</a> <a title="AJG_Vol.110.No.7 page 6" href="http://viewer.zmags.com/publication/0f57c12d?page=6"> www.amjgastro.com The American Journa</a> <a title="AJG_Vol.110.No.7 page 7" href="http://viewer.zmags.com/publication/0f57c12d?page=7"> Is oral iron therapy failing your patients? </a> <a title="AJG_Vol.110.No.7 page 8" href="http://viewer.zmags.com/publication/0f57c12d?page=8"> Inflammation in IBD and malabsorption in post-gas</a> <a title="AJG_Vol.110.No.7 page 9" href="http://viewer.zmags.com/publication/0f57c12d?page=9"> )YPLM:\TTHY`VM-\SS7YLZJYPIPUN0UMVYTH[PVU </a> <a title="AJG_Vol.110.No.7 page 10" href="http://viewer.zmags.com/publication/0f57c12d?page=10"> In active, mild to moderate ulcerative colitis (U</a> <a title="AJG_Vol.110.No.7 page 11" href="http://viewer.zmags.com/publication/0f57c12d?page=11"> BRIEF SUMMARY UCERIS (budesonide) extended releas</a> <a title="AJG_Vol.110.No.7 page 12" href="http://viewer.zmags.com/publication/0f57c12d?page=12"> RULE OUT LAL D! </a> <a title="AJG_Vol.110.No.7 page 13" href="http://viewer.zmags.com/publication/0f57c12d?page=13"> Looking for an easy way to diagnose SIBO? %</a> <a title="AJG_Vol.110.No.7 page 14" href="http://viewer.zmags.com/publication/0f57c12d?page=14"> OFFICIAL PUBLICATION OF THE AMERICAN CO</a> <a title="AJG_Vol.110.No.7 page 15" href="http://viewer.zmags.com/publication/0f57c12d?page=15"> ĆĒĊėĎĈĆēĈĔđđĊČĊĔċČĆĘęėĔĊēęĊėĔđĔČĞ ACG2015 Haw</a> <a title="AJG_Vol.110.No.7 page 16" href="http://viewer.zmags.com/publication/0f57c12d?page=16"> Albert Einstein used with permission of the HUJ/G</a> <a title="AJG_Vol.110.No.7 page 17" href="http://viewer.zmags.com/publication/0f57c12d?page=17"> HARVONI is the only HCV treatment offering an 8-w</a> <a title="AJG_Vol.110.No.7 page 18" href="http://viewer.zmags.com/publication/0f57c12d?page=18"> HARVONI is the only once-daily single-tablet regi</a> <a title="AJG_Vol.110.No.7 page 19" href="http://viewer.zmags.com/publication/0f57c12d?page=19"> HARVONI® (ledipasvir 90 mg and sofosbuvir 400 mg)</a> <a title="AJG_Vol.110.No.7 page 20" href="http://viewer.zmags.com/publication/0f57c12d?page=20"> Brief Summary (cont.) · Proton-pump inhibitors: </a> <a title="AJG_Vol.110.No.7 page 21" href="http://viewer.zmags.com/publication/0f57c12d?page=21"> INDICATION AND IMPORTANT SAFETY INFORMATION FOR H</a> <a title="AJG_Vol.110.No.7 page 22" href="http://viewer.zmags.com/publication/0f57c12d?page=22"> Achieve UC remission— </a> <a title="AJG_Vol.110.No.7 page 23" href="http://viewer.zmags.com/publication/0f57c12d?page=23"> HUMIRA® (adalimumab) </a> <a title="AJG_Vol.110.No.7 page 24" href="http://viewer.zmags.com/publication/0f57c12d?page=24"> Autoimmunity Treatment with HUMIRA may result in </a> <a title="AJG_Vol.110.No.7 page 25" href="http://viewer.zmags.com/publication/0f57c12d?page=25"> Skin reactions: Stevens Johnson Syndrome, cutaneo</a> <a title="AJG_Vol.110.No.7 page 26" href="http://viewer.zmags.com/publication/0f57c12d?page=26"> BRIEF SUMMARY OF PRESCRIBING INFORMATION This Bri</a> <a title="AJG_Vol.110.No.7 page 27" href="http://viewer.zmags.com/publication/0f57c12d?page=27"> NEW IBS-D INDICATION Now approved for the treatm</a> <a title="AJG_Vol.110.No.7 page 28" href="http://viewer.zmags.com/publication/0f57c12d?page=28"> A 20-year-old woman was admitted unresponsive and</a> <a title="AJG_Vol.110.No.7 page 29" href="http://viewer.zmags.com/publication/0f57c12d?page=29"> CONTENTS </a> <a title="AJG_Vol.110.No.7 page 30" href="http://viewer.zmags.com/publication/0f57c12d?page=30"> www.nature.com/ajg </a> <a title="AJG_Vol.110.No.7 page 31" href="http://viewer.zmags.com/publication/0f57c12d?page=31"> WEB FOCU S Genetics and Gastrointestinal Dis</a> <a title="AJG_Vol.110.No.7 page 32" href="http://viewer.zmags.com/publication/0f57c12d?page=32"> NEW Clinical Evidence Supports a New Ap</a> <a title="AJG_Vol.110.No.7 page 33" href="http://viewer.zmags.com/publication/0f57c12d?page=33"> PAID ADVERTISEMENT An Advance in the Manag</a> <a title="AJG_Vol.110.No.7 page 34" href="http://viewer.zmags.com/publication/0f57c12d?page=34"> TURNING RESEARCH INTO RECOVERY — FASTER. THAT'S T</a> <a title="AJG_Vol.110.No.7 page 35" href="http://viewer.zmags.com/publication/0f57c12d?page=35"> GI QUALITY IMPROVEMENT CONSORTIUM LTD 3 Se ing </a> <a title="AJG_Vol.110.No.7 page 36" href="http://viewer.zmags.com/publication/0f57c12d?page=36"> Can you spot what's hidden? Motility can obscure </a> <a title="AJG_Vol.110.No.7 page 37" href="http://viewer.zmags.com/publication/0f57c12d?page=37"> GlucaGen® (glucagon [rDNA origin] for injection) </a> <a title="AJG_Vol.110.No.7 page 38" href="http://viewer.zmags.com/publication/0f57c12d?page=38"> BRIEF SUMMARY Please see package insert for Full </a> <a title="AJG_Vol.110.No.7 page 39" href="http://viewer.zmags.com/publication/0f57c12d?page=39"> For the management of chronic loose and frequent </a> <a title="AJG_Vol.110.No.7 page 40" href="http://viewer.zmags.com/publication/0f57c12d?page=40"> nature publishing group </a> <a title="AJG_Vol.110.No.7 page 41" href="http://viewer.zmags.com/publication/0f57c12d?page=41"> 946 THE RED SECTION What's Hot in the RED J</a> <a title="AJG_Vol.110.No.7 page 42" href="http://viewer.zmags.com/publication/0f57c12d?page=42"> THE RED SECTION 947 What's Hot in the RED </a> <a title="AJG_Vol.110.No.7 page 43" href="http://viewer.zmags.com/publication/0f57c12d?page=43"> 948 THE RED SECTION </a> <a title="AJG_Vol.110.No.7 page 44" href="http://viewer.zmags.com/publication/0f57c12d?page=44"> colectomy decreases subsequent CRC (7,8). Metachr</a> <a title="AJG_Vol.110.No.7 page 45" href="http://viewer.zmags.com/publication/0f57c12d?page=45"> 950 THE RED SECTION Table 1. Patient chara</a> <a title="AJG_Vol.110.No.7 page 46" href="http://viewer.zmags.com/publication/0f57c12d?page=46"> Table 2. Frequency of MSI and/or IHC test orderin</a> <a title="AJG_Vol.110.No.7 page 47" href="http://viewer.zmags.com/publication/0f57c12d?page=47"> 952 THE RED SECTION Table 3. Frequency dis</a> <a title="AJG_Vol.110.No.7 page 48" href="http://viewer.zmags.com/publication/0f57c12d?page=48"> THE RED SECTION 953 Table 3. Continued Var</a> <a title="AJG_Vol.110.No.7 page 49" href="http://viewer.zmags.com/publication/0f57c12d?page=49"> 954 THE RED SECTION Table 5. Percentage of</a> <a title="AJG_Vol.110.No.7 page 50" href="http://viewer.zmags.com/publication/0f57c12d?page=50"> REFERENCES 1. Van Lier MG, De Wilt JH, Wagemaker</a> <a title="AJG_Vol.110.No.7 page 51" href="http://viewer.zmags.com/publication/0f57c12d?page=51"> 956 THE RED SECTION </a> <a title="AJG_Vol.110.No.7 page 52" href="http://viewer.zmags.com/publication/0f57c12d?page=52"> competence should be assessed after a trainee mee</a> <a title="AJG_Vol.110.No.7 page 53" href="http://viewer.zmags.com/publication/0f57c12d?page=53"> 958 THE RED SECTION non-working e-mail a</a> <a title="AJG_Vol.110.No.7 page 54" href="http://viewer.zmags.com/publication/0f57c12d?page=54"> THE RED SECTION 959 Table 2. Reported impo</a> <a title="AJG_Vol.110.No.7 page 55" href="http://viewer.zmags.com/publication/0f57c12d?page=55"> 960 THE RED SECTION Table 3. Composition o</a> <a title="AJG_Vol.110.No.7 page 56" href="http://viewer.zmags.com/publication/0f57c12d?page=56"> quality of training and assessment of competence </a> <a title="AJG_Vol.110.No.7 page 57" href="http://viewer.zmags.com/publication/0f57c12d?page=57"> 962 THE RED SECTION 20. Baxter NN, Warren</a> <a title="AJG_Vol.110.No.7 page 58" href="http://viewer.zmags.com/publication/0f57c12d?page=58"> nature publishing group </a> <a title="AJG_Vol.110.No.7 page 59" href="http://viewer.zmags.com/publication/0f57c12d?page=59"> 964 THE RED SECTION </a> <a title="AJG_Vol.110.No.7 page 60" href="http://viewer.zmags.com/publication/0f57c12d?page=60"> nature publishing group </a> <a title="AJG_Vol.110.No.7 page 61" href="http://viewer.zmags.com/publication/0f57c12d?page=61"> 966 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.110.No.7 page 62" href="http://viewer.zmags.com/publication/0f57c12d?page=62"> nature publishing group </a> <a title="AJG_Vol.110.No.7 page 63" href="http://viewer.zmags.com/publication/0f57c12d?page=63"> 968 Carlson et al. ESOPHAGUS the entire le</a> <a title="AJG_Vol.110.No.7 page 64" href="http://viewer.zmags.com/publication/0f57c12d?page=64"> Diagnosis of Esophageal Motility Disorders 96</a> <a title="AJG_Vol.110.No.7 page 65" href="http://viewer.zmags.com/publication/0f57c12d?page=65"> 970 Carlson et al. ESOPHAGUS (Given Imagin</a> <a title="AJG_Vol.110.No.7 page 66" href="http://viewer.zmags.com/publication/0f57c12d?page=66"> Table 1B. Classification criteria utilized for con</a> <a title="AJG_Vol.110.No.7 page 67" href="http://viewer.zmags.com/publication/0f57c12d?page=67"> 972 Carlson et al. ESOPHAGUS Table 2A. Con</a> <a title="AJG_Vol.110.No.7 page 68" href="http://viewer.zmags.com/publication/0f57c12d?page=68"> 100% 90% 80% 70% 60% 50% Major inaccuracy </a> <a title="AJG_Vol.110.No.7 page 69" href="http://viewer.zmags.com/publication/0f57c12d?page=69"> 974 Carlson et al. ESOPHAGUS Table 5A. Int</a> <a title="AJG_Vol.110.No.7 page 70" href="http://viewer.zmags.com/publication/0f57c12d?page=70"> pressure or distal contractile integral. Another </a> <a title="AJG_Vol.110.No.7 page 71" href="http://viewer.zmags.com/publication/0f57c12d?page=71"> 976 Carlson et al. ESOPHAGUS minimal previ</a> <a title="AJG_Vol.110.No.7 page 72" href="http://viewer.zmags.com/publication/0f57c12d?page=72"> 17. Fleiss JL. Measuring nominal scale agreement </a> <a title="AJG_Vol.110.No.7 page 73" href="http://viewer.zmags.com/publication/0f57c12d?page=73"> 978 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.110.No.7 page 74" href="http://viewer.zmags.com/publication/0f57c12d?page=74"> nature publishing group </a> <a title="AJG_Vol.110.No.7 page 75" href="http://viewer.zmags.com/publication/0f57c12d?page=75"> 980 Ratuapli et al. ESOPHAGUS METHODS Subj</a> <a title="AJG_Vol.110.No.7 page 76" href="http://viewer.zmags.com/publication/0f57c12d?page=76"> Table 1. Demographic characteristics and measures</a> <a title="AJG_Vol.110.No.7 page 77" href="http://viewer.zmags.com/publication/0f57c12d?page=77"> 982 Ratuapli et al. 30% 25% 20% </a> <a title="AJG_Vol.110.No.7 page 78" href="http://viewer.zmags.com/publication/0f57c12d?page=78"> Opioids and Esophageal Motility 983 Chro</a> <a title="AJG_Vol.110.No.7 page 79" href="http://viewer.zmags.com/publication/0f57c12d?page=79"> 984 Ratuapli et al. ESOPHAGUS providing a </a> <a title="AJG_Vol.110.No.7 page 80" href="http://viewer.zmags.com/publication/0f57c12d?page=80"> nature publishing group </a> <a title="AJG_Vol.110.No.7 page 81" href="http://viewer.zmags.com/publication/0f57c12d?page=81"> 986 Reverter et al. LIVER the liver (3). A</a> <a title="AJG_Vol.110.No.7 page 82" href="http://viewer.zmags.com/publication/0f57c12d?page=82"> the dose was increased to 10 mg/kg/day oral b.i.d</a> <a title="AJG_Vol.110.No.7 page 83" href="http://viewer.zmags.com/publication/0f57c12d?page=83"> 988 Reverter et al. LIVER Placebo</a> <a title="AJG_Vol.110.No.7 page 84" href="http://viewer.zmags.com/publication/0f57c12d?page=84"> Sapropterin in Patients With Cirrhosis 989 </a> <a title="AJG_Vol.110.No.7 page 85" href="http://viewer.zmags.com/publication/0f57c12d?page=85"> 990 Reverter et al. 30 25 20 </a> <a title="AJG_Vol.110.No.7 page 86" href="http://viewer.zmags.com/publication/0f57c12d?page=86"> not planned in the present study and, conversely,</a> <a title="AJG_Vol.110.No.7 page 87" href="http://viewer.zmags.com/publication/0f57c12d?page=87"> 992 Reverter et al. LIVER REFERENCES 1. B</a> <a title="AJG_Vol.110.No.7 page 88" href="http://viewer.zmags.com/publication/0f57c12d?page=88"> nature publishing group </a> <a title="AJG_Vol.110.No.7 page 89" href="http://viewer.zmags.com/publication/0f57c12d?page=89"> 994 Dhaliwal et al. LIVER is now defined a</a> <a title="AJG_Vol.110.No.7 page 90" href="http://viewer.zmags.com/publication/0f57c12d?page=90"> another pathologist (JCEU) in order to measure th</a> <a title="AJG_Vol.110.No.7 page 91" href="http://viewer.zmags.com/publication/0f57c12d?page=91"> 996 Dhaliwal et al. LIVER Table 1. Demogra</a> <a title="AJG_Vol.110.No.7 page 92" href="http://viewer.zmags.com/publication/0f57c12d?page=92"> Table 4. Causes of death according to histologica</a> <a title="AJG_Vol.110.No.7 page 93" href="http://viewer.zmags.com/publication/0f57c12d?page=93"> 998 Dhaliwal et al. LIVER who had a HAI of</a> <a title="AJG_Vol.110.No.7 page 94" href="http://viewer.zmags.com/publication/0f57c12d?page=94"> increase long-term mortality (e.g., by increasing</a> <a title="AJG_Vol.110.No.7 page 95" href="http://viewer.zmags.com/publication/0f57c12d?page=95"> 1000 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.110.No.7 page 96" href="http://viewer.zmags.com/publication/0f57c12d?page=96"> nature publishing group </a> <a title="AJG_Vol.110.No.7 page 97" href="http://viewer.zmags.com/publication/0f57c12d?page=97"> 1002 Targownik et al. INFLAMMATORY BOWEL DI</a> <a title="AJG_Vol.110.No.7 page 98" href="http://viewer.zmags.com/publication/0f57c12d?page=98"> than at the present moment. A cutoff of ≥5 has be</a> <a title="AJG_Vol.110.No.7 page 99" href="http://viewer.zmags.com/publication/0f57c12d?page=99"> 1004 Targownik et al. OWEL DISEASE INFLAMMA</a> <a title="AJG_Vol.110.No.7 page 100" href="http://viewer.zmags.com/publication/0f57c12d?page=100"> Perceived Stress, Inflammation, and Symptoms in I</a> <a title="AJG_Vol.110.No.7 page 101" href="http://viewer.zmags.com/publication/0f57c12d?page=101"> 1006 Targownik et al. INFLAMMATORY BOWEL DI</a> <a title="AJG_Vol.110.No.7 page 102" href="http://viewer.zmags.com/publication/0f57c12d?page=102"> Perceived Stress, Inflammation, and Symptoms in I</a> <a title="AJG_Vol.110.No.7 page 103" href="http://viewer.zmags.com/publication/0f57c12d?page=103"> 1008 Targownik et al. INFLAMMATORY BOWEL DI</a> <a title="AJG_Vol.110.No.7 page 104" href="http://viewer.zmags.com/publication/0f57c12d?page=104"> Table 7. Logistic regression: association between</a> <a title="AJG_Vol.110.No.7 page 105" href="http://viewer.zmags.com/publication/0f57c12d?page=105"> 1010 Targownik et al. INFLAMMATORY BOWEL DI</a> <a title="AJG_Vol.110.No.7 page 106" href="http://viewer.zmags.com/publication/0f57c12d?page=106"> Study Highlights WHAT IS CURRENT KNOWLEDGE ✓ Per</a> <a title="AJG_Vol.110.No.7 page 107" href="http://viewer.zmags.com/publication/0f57c12d?page=107"> 1012 Targownik et al. INFLAMMATORY BOWEL DI</a> <a title="AJG_Vol.110.No.7 page 108" href="http://viewer.zmags.com/publication/0f57c12d?page=108"> nature publishing group </a> <a title="AJG_Vol.110.No.7 page 109" href="http://viewer.zmags.com/publication/0f57c12d?page=109"> 1014 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.110.No.7 page 110" href="http://viewer.zmags.com/publication/0f57c12d?page=110"> multiple random biopsies throughout the entire co</a> <a title="AJG_Vol.110.No.7 page 111" href="http://viewer.zmags.com/publication/0f57c12d?page=111"> 1016 Mooiweer et al. neoplasia yield o</a> <a title="AJG_Vol.110.No.7 page 112" href="http://viewer.zmags.com/publication/0f57c12d?page=112"> Chromoendoscopy for Surveillance in IBD 1017 </a> <a title="AJG_Vol.110.No.7 page 113" href="http://viewer.zmags.com/publication/0f57c12d?page=113"> 1018 Mooiweer et al. INFLAMMATORY BOWEL DIS</a> <a title="AJG_Vol.110.No.7 page 114" href="http://viewer.zmags.com/publication/0f57c12d?page=114"> have affected the quality of the procedures. As b</a> <a title="AJG_Vol.110.No.7 page 115" href="http://viewer.zmags.com/publication/0f57c12d?page=115"> 1020 Mooiweer et al. INFLAMMATORY BOWEL DIS</a> <a title="AJG_Vol.110.No.7 page 116" href="http://viewer.zmags.com/publication/0f57c12d?page=116"> 4. Winawer S, Fletcher R, Rex D et al. Colorecta</a> <a title="AJG_Vol.110.No.7 page 117" href="http://viewer.zmags.com/publication/0f57c12d?page=117"> 1022 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.110.No.7 page 118" href="http://viewer.zmags.com/publication/0f57c12d?page=118"> Second, there are limited data on the risk of C</a> <a title="AJG_Vol.110.No.7 page 119" href="http://viewer.zmags.com/publication/0f57c12d?page=119"> 1024 Choi et al. 1. Per-Protocol Surv</a> <a title="AJG_Vol.110.No.7 page 120" href="http://viewer.zmags.com/publication/0f57c12d?page=120"> Table 1. Primary end point categorization Primary</a> <a title="AJG_Vol.110.No.7 page 121" href="http://viewer.zmags.com/publication/0f57c12d?page=121"> 1026 Choi et al. a 1.0 NFLAMMATORY </a> <a title="AJG_Vol.110.No.7 page 122" href="http://viewer.zmags.com/publication/0f57c12d?page=122"> Cancer Surveillance in Ulcerative Colitis 102</a> <a title="AJG_Vol.110.No.7 page 123" href="http://viewer.zmags.com/publication/0f57c12d?page=123"> 1028 Choi et al. INFLAMMATORY BOWEL DISEASE</a> <a title="AJG_Vol.110.No.7 page 124" href="http://viewer.zmags.com/publication/0f57c12d?page=124"> Cancer Surveillance in Ulcerative Colitis 102</a> <a title="AJG_Vol.110.No.7 page 125" href="http://viewer.zmags.com/publication/0f57c12d?page=125"> 1030 Choi et al. a 1.0 INFLAMMATORY</a> <a title="AJG_Vol.110.No.7 page 126" href="http://viewer.zmags.com/publication/0f57c12d?page=126"> Cancer Surveillance in Ulcerative Colitis 103</a> <a title="AJG_Vol.110.No.7 page 127" href="http://viewer.zmags.com/publication/0f57c12d?page=127"> 1032 Choi et al. INFLAMMATORY BOWEL DISEASE</a> <a title="AJG_Vol.110.No.7 page 128" href="http://viewer.zmags.com/publication/0f57c12d?page=128"> is well documented that grading of dysplasia is d</a> <a title="AJG_Vol.110.No.7 page 129" href="http://viewer.zmags.com/publication/0f57c12d?page=129"> 1034 Choi et al. INFLAMMATORY BOWEL DISEASE</a> <a title="AJG_Vol.110.No.7 page 130" href="http://viewer.zmags.com/publication/0f57c12d?page=130"> nature publishing group </a> <a title="AJG_Vol.110.No.7 page 131" href="http://viewer.zmags.com/publication/0f57c12d?page=131"> 1036 Higgins INFLAMMATORY BOWEL DISEASE al</a> <a title="AJG_Vol.110.No.7 page 132" href="http://viewer.zmags.com/publication/0f57c12d?page=132"> chromoendoscopy for the reduction in colon cancer</a> <a title="AJG_Vol.110.No.7 page 133" href="http://viewer.zmags.com/publication/0f57c12d?page=133"> 1038 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.110.No.7 page 134" href="http://viewer.zmags.com/publication/0f57c12d?page=134"> is not infrequent (3), with the most commonly see</a> <a title="AJG_Vol.110.No.7 page 135" href="http://viewer.zmags.com/publication/0f57c12d?page=135"> 1040 Pinto-Sanchez et al. GI DISORDERS FUNC</a> <a title="AJG_Vol.110.No.7 page 136" href="http://viewer.zmags.com/publication/0f57c12d?page=136"> reporting symptoms and no underlying organic dise</a> <a title="AJG_Vol.110.No.7 page 137" href="http://viewer.zmags.com/publication/0f57c12d?page=137"> 1042 Pinto-Sanchez et al. GI DISORDERS FUNC</a> <a title="AJG_Vol.110.No.7 page 138" href="http://viewer.zmags.com/publication/0f57c12d?page=138"> FGID compared with those not meeting criteria for</a> <a title="AJG_Vol.110.No.7 page 139" href="http://viewer.zmags.com/publication/0f57c12d?page=139"> 1044 Pinto-Sanchez et al. GI DISORDERS FUNC</a> <a title="AJG_Vol.110.No.7 page 140" href="http://viewer.zmags.com/publication/0f57c12d?page=140"> 50 40 30 % Of patients 20 10 0 </a> <a title="AJG_Vol.110.No.7 page 141" href="http://viewer.zmags.com/publication/0f57c12d?page=141"> 1046 Pinto-Sanchez et al. FUNCTIONAL GI DIS</a> <a title="AJG_Vol.110.No.7 page 142" href="http://viewer.zmags.com/publication/0f57c12d?page=142"> awareness of the association for better psychosoc</a> <a title="AJG_Vol.110.No.7 page 143" href="http://viewer.zmags.com/publication/0f57c12d?page=143"> 1048 Pinto-Sanchez et al. FUNCTIONAL GI DIS</a> <a title="AJG_Vol.110.No.7 page 144" href="http://viewer.zmags.com/publication/0f57c12d?page=144"> nature publishing group </a> <a title="AJG_Vol.110.No.7 page 145" href="http://viewer.zmags.com/publication/0f57c12d?page=145"> 1050 Staller et al. FUNCTIONAL GI DISORDERS</a> <a title="AJG_Vol.110.No.7 page 146" href="http://viewer.zmags.com/publication/0f57c12d?page=146"> manometry, which occurred in November 2009. The b</a> <a title="AJG_Vol.110.No.7 page 147" href="http://viewer.zmags.com/publication/0f57c12d?page=147"> 1052 Staller et al. GI DISORDERS FUNCTIONAL</a> <a title="AJG_Vol.110.No.7 page 148" href="http://viewer.zmags.com/publication/0f57c12d?page=148"> Table 4. Likelihood of anorectal manometry/balloo</a> <a title="AJG_Vol.110.No.7 page 149" href="http://viewer.zmags.com/publication/0f57c12d?page=149"> 1054 Staller et al. GI DISORDERS FUNCTIONAL</a> <a title="AJG_Vol.110.No.7 page 150" href="http://viewer.zmags.com/publication/0f57c12d?page=150"> 11. Charlson ME, Pompei P, Ales KL et al. A new m</a> <a title="AJG_Vol.110.No.7 page 151" href="http://viewer.zmags.com/publication/0f57c12d?page=151"> 1056 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.110.No.7 page 152" href="http://viewer.zmags.com/publication/0f57c12d?page=152"> No direct contact with either patients or provide</a> <a title="AJG_Vol.110.No.7 page 153" href="http://viewer.zmags.com/publication/0f57c12d?page=153"> 1058 Sonnenberg and Genta COLON/SMALL BOWEL</a> <a title="AJG_Vol.110.No.7 page 154" href="http://viewer.zmags.com/publication/0f57c12d?page=154"> Polyps in Colonic Inflammation 1059 Table</a> <a title="AJG_Vol.110.No.7 page 155" href="http://viewer.zmags.com/publication/0f57c12d?page=155"> 1060 Sonnenberg and Genta COLON/SMALL BOWEL</a> <a title="AJG_Vol.110.No.7 page 156" href="http://viewer.zmags.com/publication/0f57c12d?page=156"> CONFLICT OF INTEREST Guarantor of the article: Am</a> <a title="AJG_Vol.110.No.7 page 157" href="http://viewer.zmags.com/publication/0f57c12d?page=157"> 1062 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.110.No.7 page 158" href="http://viewer.zmags.com/publication/0f57c12d?page=158"> comply with patient preferences (7,8). A reliable</a> <a title="AJG_Vol.110.No.7 page 159" href="http://viewer.zmags.com/publication/0f57c12d?page=159"> 1064 Schroy et al. COLON/SMALL BOWEL covar</a> <a title="AJG_Vol.110.No.7 page 160" href="http://viewer.zmags.com/publication/0f57c12d?page=160"> Patients referred for screening colonoscopy </a> <a title="AJG_Vol.110.No.7 page 161" href="http://viewer.zmags.com/publication/0f57c12d?page=161"> 1066 Schroy et al. COLON/SMALL BOWEL Table</a> <a title="AJG_Vol.110.No.7 page 162" href="http://viewer.zmags.com/publication/0f57c12d?page=162"> Risk Index for Advanced Colorectal Neoplasia </a> <a title="AJG_Vol.110.No.7 page 163" href="http://viewer.zmags.com/publication/0f57c12d?page=163"> 1068 Schroy et al. SMALL BOWEL COLON/ Tabl</a> <a title="AJG_Vol.110.No.7 page 164" href="http://viewer.zmags.com/publication/0f57c12d?page=164"> risk index proposed by Imperiale et al. (48), our</a> <a title="AJG_Vol.110.No.7 page 165" href="http://viewer.zmags.com/publication/0f57c12d?page=165"> 1070 Schroy et al. COLON/SMALL BOWEL Study</a> <a title="AJG_Vol.110.No.7 page 166" href="http://viewer.zmags.com/publication/0f57c12d?page=166"> (last accessed on 23 May 2014, based on No</a> <a title="AJG_Vol.110.No.7 page 167" href="http://viewer.zmags.com/publication/0f57c12d?page=167"> 1072 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.110.No.7 page 168" href="http://viewer.zmags.com/publication/0f57c12d?page=168"> Although these colonoscopies can have a substanti</a> <a title="AJG_Vol.110.No.7 page 169" href="http://viewer.zmags.com/publication/0f57c12d?page=169"> 1074 Grobbee et al. COLON/SMALL BOWEL Tabl</a> <a title="AJG_Vol.110.No.7 page 170" href="http://viewer.zmags.com/publication/0f57c12d?page=170"> Table 3. Characteristics of most advanced polyps </a> <a title="AJG_Vol.110.No.7 page 171" href="http://viewer.zmags.com/publication/0f57c12d?page=171"> 1076 Grobbee et al. COLON/SMALL BOWEL Tabl</a> <a title="AJG_Vol.110.No.7 page 172" href="http://viewer.zmags.com/publication/0f57c12d?page=172"> Eiken Chemical, Tokyo, Japan. The funding sources</a> <a title="AJG_Vol.110.No.7 page 173" href="http://viewer.zmags.com/publication/0f57c12d?page=173"> 1078 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.110.No.7 page 174" href="http://viewer.zmags.com/publication/0f57c12d?page=174"> cost-effectiveness of the second biopsy remains o</a> <a title="AJG_Vol.110.No.7 page 175" href="http://viewer.zmags.com/publication/0f57c12d?page=175"> 1080 Pekki et al. COLON/SMALL BOWEL Phadia</a> <a title="AJG_Vol.110.No.7 page 176" href="http://viewer.zmags.com/publication/0f57c12d?page=176"> Table 1. Baseline demographic data, clinical char</a> <a title="AJG_Vol.110.No.7 page 177" href="http://viewer.zmags.com/publication/0f57c12d?page=177"> 1082 Pekki et al. COLON/SMALL BOWEL Table </a> <a title="AJG_Vol.110.No.7 page 178" href="http://viewer.zmags.com/publication/0f57c12d?page=178"> Table 5. Long-term follow-up data on 205 celiac d</a> <a title="AJG_Vol.110.No.7 page 179" href="http://viewer.zmags.com/publication/0f57c12d?page=179"> 1084 Pekki et al. COLON/SMALL BOWEL remain</a> <a title="AJG_Vol.110.No.7 page 180" href="http://viewer.zmags.com/publication/0f57c12d?page=180"> Study Highlights WHAT IS CURRENT KNOWLEDGE ✓ Fol</a> <a title="AJG_Vol.110.No.7 page 181" href="http://viewer.zmags.com/publication/0f57c12d?page=181"> 1086 LETTERS TO THE EDITOR </a> <a title="AJG_Vol.110.No.7 page 182" href="http://viewer.zmags.com/publication/0f57c12d?page=182"> nature publishing group </a> <a title="AJG_Vol.110.No.7 page 183" href="http://viewer.zmags.com/publication/0f57c12d?page=183"> 1088 Letters to the Editor </a> <a title="AJG_Vol.110.No.7 page 184" href="http://viewer.zmags.com/publication/0f57c12d?page=184"> nature publishing group </a> <a title="AJG_Vol.110.No.7 page 185" href="http://viewer.zmags.com/publication/0f57c12d?page=185"> 1090 Announcements ARIZONA Phoenix Bann</a> <a title="AJG_Vol.110.No.7 page 186" href="http://viewer.zmags.com/publication/0f57c12d?page=186"> Childrens Hospital Los Angeles Pediatric Gastroen</a> <a 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