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<br /> March 2019 Vol 4.1<br /> + RESPIRATORY<br /> Rocking Pneumonia and the Boogie<br /> Woogie Flu<br /> + DERMATOLOGY<br /> Clinical Conditions that Masquerade<br /> ISSN: 2397-6764 as Urticaria<br /> + ALLERGY AND IMMUNOLOGY<br /> Why Do People Misdiagnose Themselves<br /> with Food Hypersensitivity?<br /> + EDITOR'S PICK<br /> Bronchopulmonary Dysplasia: An Update<br /> on Experimental Therapeutics<br /> europeanmedical-journal.com<br /> Bringing<br /> MCG to the<br /> point-of-care<br /> Corsens® ED is the first cardiac<br /> diagnostic device to bring<br /> magnetocardiography (MCG)<br /> magnetocardiography (MCG)<br /> directly to the patient’s bedside.<br /> Creavo's novel MCG technology captures<br /> the minute magnetic signals associated<br /> with the heart’s electrical activity, via a<br /> non-invasive be<a title="EMJ 4.1 2019 page 1" href="http://viewer.zmags.com/publication/137491e8?page=1"> March 2019 Vol 4.1 + RESPIRATORY Rocking Pne</a> <a title="EMJ 4.1 2019 page 2" href="http://viewer.zmags.com/publication/137491e8?page=2"> Bringing MCG to the point-of-care Corsens® ED</a> <a title="EMJ 4.1 2019 page 3" href="http://viewer.zmags.com/publication/137491e8?page=3"> Xarelto®. Tailored Protection for Your Cardio-Vas</a> <a title="EMJ 4.1 2019 page 4" href="http://viewer.zmags.com/publication/137491e8?page=4"> Contents EDITORIAL BOARD </a> <a title="EMJ 4.1 2019 page 5" href="http://viewer.zmags.com/publication/137491e8?page=5"> “Whether you are a fledgling physician looking </a> <a title="EMJ 4.1 2019 page 6" href="http://viewer.zmags.com/publication/137491e8?page=6"> Editorial Board Editor-in-Chief Prof Markus Peck-</a> <a title="EMJ 4.1 2019 page 7" href="http://viewer.zmags.com/publication/137491e8?page=7"> Aims and Scope The European Medical Journal (EMJ)</a> <a title="EMJ 4.1 2019 page 8" href="http://viewer.zmags.com/publication/137491e8?page=8"> EMJ 4.1 Chief Executive Officer Spencer Gore Seni</a> <a title="EMJ 4.1 2019 page 9" href="http://viewer.zmags.com/publication/137491e8?page=9"> Welcome Spring is upon us, and with it comes a ho</a> <a title="EMJ 4.1 2019 page 10" href="http://viewer.zmags.com/publication/137491e8?page=10"> Non-melanoma skin cancer (NMSC): Getting to the </a> <a title="EMJ 4.1 2019 page 11" href="http://viewer.zmags.com/publication/137491e8?page=11"> Dear col It is a ple present Is there allergy? fo</a> <a title="EMJ 4.1 2019 page 12" href="http://viewer.zmags.com/publication/137491e8?page=12"> Discover the Potential: Exploring New F</a> <a title="EMJ 4.1 2019 page 13" href="http://viewer.zmags.com/publication/137491e8?page=13"> individualised as much as possible. The symposium</a> <a title="EMJ 4.1 2019 page 14" href="http://viewer.zmags.com/publication/137491e8?page=14"> moderate-to-severe psoriasis (p<0.05).16 In</a> <a title="EMJ 4.1 2019 page 15" href="http://viewer.zmags.com/publication/137491e8?page=15"> pathogenic Th17 cell expansion and survival in ea</a> <a title="EMJ 4.1 2019 page 16" href="http://viewer.zmags.com/publication/137491e8?page=16"> randomised, double-blind, placebo-controlled, a</a> <a title="EMJ 4.1 2019 page 17" href="http://viewer.zmags.com/publication/137491e8?page=17"> oral administration. Other options might include </a> <a title="EMJ 4.1 2019 page 18" href="http://viewer.zmags.com/publication/137491e8?page=18"> thought to be activated and maintained by the pat</a> <a title="EMJ 4.1 2019 page 19" href="http://viewer.zmags.com/publication/137491e8?page=19"> moderate to severe plaque psoriasis: A randomized</a> <a title="EMJ 4.1 2019 page 20" href="http://viewer.zmags.com/publication/137491e8?page=20"> Bronchopulmonary Dysplasia: An Update on </a> <a title="EMJ 4.1 2019 page 21" href="http://viewer.zmags.com/publication/137491e8?page=21"> INTRODUCTION Bronchopulmonary dysplasia (BPD) is </a> <a title="EMJ 4.1 2019 page 22" href="http://viewer.zmags.com/publication/137491e8?page=22"> In the case of severe BPD, the diagnosis </a> <a title="EMJ 4.1 2019 page 23" href="http://viewer.zmags.com/publication/137491e8?page=23"> Intralipid® (Fresenius Kabi) (which vary in PUFA </a> <a title="EMJ 4.1 2019 page 24" href="http://viewer.zmags.com/publication/137491e8?page=24"> Regarding natural products such as flavonols, whic</a> <a title="EMJ 4.1 2019 page 25" href="http://viewer.zmags.com/publication/137491e8?page=25"> are used either alone or in combination with vent</a> <a title="EMJ 4.1 2019 page 26" href="http://viewer.zmags.com/publication/137491e8?page=26"> preterm infants who received HM-derived cream, it</a> <a title="EMJ 4.1 2019 page 27" href="http://viewer.zmags.com/publication/137491e8?page=27"> Table 3 continued. Therapeutic agent Type of </a> <a title="EMJ 4.1 2019 page 28" href="http://viewer.zmags.com/publication/137491e8?page=28"> References 1. Northway WH et al. Pulmonary </a> <a title="EMJ 4.1 2019 page 29" href="http://viewer.zmags.com/publication/137491e8?page=29"> Perspectives from newborn medicine. Methods Mol B</a> <a title="EMJ 4.1 2019 page 30" href="http://viewer.zmags.com/publication/137491e8?page=30"> Why Do People Misdiagnose Themselves with Food Hy</a> <a title="EMJ 4.1 2019 page 31" href="http://viewer.zmags.com/publication/137491e8?page=31"> has therefore been associated with stress, worry,</a> <a title="EMJ 4.1 2019 page 32" href="http://viewer.zmags.com/publication/137491e8?page=32"> low molecular mass chemicals (e.g., salicylates, </a> <a title="EMJ 4.1 2019 page 33" href="http://viewer.zmags.com/publication/137491e8?page=33"> taste were more likely to give more plausible acc</a> <a title="EMJ 4.1 2019 page 34" href="http://viewer.zmags.com/publication/137491e8?page=34"> seen in a reference sample of NHS and university </a> <a title="EMJ 4.1 2019 page 35" href="http://viewer.zmags.com/publication/137491e8?page=35"> with symptoms in the past that caused distress, s</a> <a title="EMJ 4.1 2019 page 36" href="http://viewer.zmags.com/publication/137491e8?page=36"> mothers. Pediatr Allergy Immunol. 2010;21(4p1):58</a> <a title="EMJ 4.1 2019 page 37" href="http://viewer.zmags.com/publication/137491e8?page=37"> 1992;42:77-85. </a> <a title="EMJ 4.1 2019 page 38" href="http://viewer.zmags.com/publication/137491e8?page=38"> INTERNATIONAL WORKSHOP ON CHRONIC LYMPHOC 20-23 S</a> <a title="EMJ 4.1 2019 page 39" href="http://viewer.zmags.com/publication/137491e8?page=39"> Clinical Conditions that Masquerade as Urticaria </a> <a title="EMJ 4.1 2019 page 40" href="http://viewer.zmags.com/publication/137491e8?page=40"> Box 1: Common and less common or uncommon causes </a> <a title="EMJ 4.1 2019 page 41" href="http://viewer.zmags.com/publication/137491e8?page=41"> CU. These include erythema marginatum (EM) seen i</a> <a title="EMJ 4.1 2019 page 42" href="http://viewer.zmags.com/publication/137491e8?page=42"> Table 1: Characterisation of urticaria versus aut</a> <a title="EMJ 4.1 2019 page 43" href="http://viewer.zmags.com/publication/137491e8?page=43"> URTICARIAL VASCULITIS Up to 15% of refrac</a> <a title="EMJ 4.1 2019 page 44" href="http://viewer.zmags.com/publication/137491e8?page=44"> Other common symptoms include fever, </a> <a title="EMJ 4.1 2019 page 45" href="http://viewer.zmags.com/publication/137491e8?page=45"> ESR), elevated eosinophils and neutrophils, and l</a> <a title="EMJ 4.1 2019 page 46" href="http://viewer.zmags.com/publication/137491e8?page=46"> achieve symptomatic relief. Antiviral therapy for</a> <a title="EMJ 4.1 2019 page 47" href="http://viewer.zmags.com/publication/137491e8?page=47"> References 1. Fine LM, Bernstein JA. Guideli</a> <a title="EMJ 4.1 2019 page 48" href="http://viewer.zmags.com/publication/137491e8?page=48"> Rocking Pneumonia and the Boogie Woogie Flu Aut</a> <a title="EMJ 4.1 2019 page 49" href="http://viewer.zmags.com/publication/137491e8?page=49"> BETWEEN INFLUENZA AND PNEUMONI THE EPIDEMIOLOGIC</a> <a title="EMJ 4.1 2019 page 50" href="http://viewer.zmags.com/publication/137491e8?page=50"> 180 160 140 Incidence per 100,000 people 12</a> <a title="EMJ 4.1 2019 page 51" href="http://viewer.zmags.com/publication/137491e8?page=51"> complication rate of pneumococcal infection, due </a> <a title="EMJ 4.1 2019 page 52" href="http://viewer.zmags.com/publication/137491e8?page=52"> mucus, surfactants, and other inflammatory med</a> <a title="EMJ 4.1 2019 page 53" href="http://viewer.zmags.com/publication/137491e8?page=53"> in a substantial number of patients w</a> <a title="EMJ 4.1 2019 page 54" href="http://viewer.zmags.com/publication/137491e8?page=54"> 30. Butler JC et al. Pneumococcal </a> <a title="EMJ 4.1 2019 page 55" href="http://viewer.zmags.com/publication/137491e8?page=55"> Persistent Cough: Changes in Prevalence, Impact</a> <a title="EMJ 4.1 2019 page 56" href="http://viewer.zmags.com/publication/137491e8?page=56"> INTRODUCTION Persistent cough is one of the most </a> <a title="EMJ 4.1 2019 page 57" href="http://viewer.zmags.com/publication/137491e8?page=57"> Box 1: The questions asked of each of the partici</a> <a title="EMJ 4.1 2019 page 58" href="http://viewer.zmags.com/publication/137491e8?page=58"> As previously mentioned, the sampling</a> <a title="EMJ 4.1 2019 page 59" href="http://viewer.zmags.com/publication/137491e8?page=59"> Table 1: General characteristics of the 2006 and </a> <a title="EMJ 4.1 2019 page 60" href="http://viewer.zmags.com/publication/137491e8?page=60"> Respondents’ Therapeutic Expectations The major</a> <a title="EMJ 4.1 2019 page 61" href="http://viewer.zmags.com/publication/137491e8?page=61"> The results of the study emphasise that th</a> <a title="EMJ 4.1 2019 page 62" href="http://viewer.zmags.com/publication/137491e8?page=62"> while persistent cough in children is much more f</a> <a title="EMJ 4.1 2019 page 63" href="http://viewer.zmags.com/publication/137491e8?page=63"> Obesity: The Impact on Host Systems Affecting M</a> <a title="EMJ 4.1 2019 page 64" href="http://viewer.zmags.com/publication/137491e8?page=64"> INTRODUCTION Obesity has become an epidemic accor</a> <a title="EMJ 4.1 2019 page 65" href="http://viewer.zmags.com/publication/137491e8?page=65"> glucose metabolism and the combination of T2</a> <a title="EMJ 4.1 2019 page 66" href="http://viewer.zmags.com/publication/137491e8?page=66"> with tendinopathies.31 Recently, it has been </a> <a title="EMJ 4.1 2019 page 67" href="http://viewer.zmags.com/publication/137491e8?page=67"> the alterations in the VH of the eye, whether the</a> <a title="EMJ 4.1 2019 page 68" href="http://viewer.zmags.com/publication/137491e8?page=68"> with it (i.e., MetS), likely impacts host tissues</a> <a title="EMJ 4.1 2019 page 69" href="http://viewer.zmags.com/publication/137491e8?page=69"> 6. Wang T et al. Genetic susceptibility, </a> <a title="EMJ 4.1 2019 page 70" href="http://viewer.zmags.com/publication/137491e8?page=70"> of refined dietary sugars (fructose and glucose) i</a> <a title="EMJ 4.1 2019 page 71" href="http://viewer.zmags.com/publication/137491e8?page=71"> Inflammation and Thrombosis in Coronary At</a> <a title="EMJ 4.1 2019 page 72" href="http://viewer.zmags.com/publication/137491e8?page=72"> the complications triggered by inflammation. T</a> <a title="EMJ 4.1 2019 page 73" href="http://viewer.zmags.com/publication/137491e8?page=73"> CORONARY ARTERY DISEASE INFLAMMATORY MARKERS AND</a> <a title="EMJ 4.1 2019 page 74" href="http://viewer.zmags.com/publication/137491e8?page=74"> Cardiac risk Haemodynamic factors </a> <a title="EMJ 4.1 2019 page 75" href="http://viewer.zmags.com/publication/137491e8?page=75"> erosion differ on the role of inflammatory cells a</a> <a title="EMJ 4.1 2019 page 76" href="http://viewer.zmags.com/publication/137491e8?page=76"> Cigarette smoke exposure alters the haemostatic p</a> <a title="EMJ 4.1 2019 page 77" href="http://viewer.zmags.com/publication/137491e8?page=77"> elevated hsCRP had a significant reduction in</a> <a title="EMJ 4.1 2019 page 78" href="http://viewer.zmags.com/publication/137491e8?page=78"> 14. Ridker PM et al. Development and </a> <a title="EMJ 4.1 2019 page 79" href="http://viewer.zmags.com/publication/137491e8?page=79"> Updating the Impact of Lipid Metabolism </a> <a title="EMJ 4.1 2019 page 80" href="http://viewer.zmags.com/publication/137491e8?page=80"> is approved for clinical use, cryopreservati</a> <a title="EMJ 4.1 2019 page 81" href="http://viewer.zmags.com/publication/137491e8?page=81"> affected differently between immature oocytes sur</a> <a title="EMJ 4.1 2019 page 82" href="http://viewer.zmags.com/publication/137491e8?page=82"> ALTERING LIPID METABOLISM AND MEMBRANE COMPOSITIO</a> <a title="EMJ 4.1 2019 page 83" href="http://viewer.zmags.com/publication/137491e8?page=83"> of oocytes matured in vitro.47 Paschoal et al.48 </a> <a title="EMJ 4.1 2019 page 84" href="http://viewer.zmags.com/publication/137491e8?page=84"> content, CLA addition to IVP media had no </a> <a title="EMJ 4.1 2019 page 85" href="http://viewer.zmags.com/publication/137491e8?page=85"> the composition of the lipid profile of oocytes, P</a> <a title="EMJ 4.1 2019 page 86" href="http://viewer.zmags.com/publication/137491e8?page=86"> References 1. Cobo A, Diaz C. Clinical appli</a> <a title="EMJ 4.1 2019 page 87" href="http://viewer.zmags.com/publication/137491e8?page=87"> Biochem Sci. 2010;35(9):505-13. 43. Tiwari M, Ch</a> <a title="EMJ 4.1 2019 page 88" href="http://viewer.zmags.com/publication/137491e8?page=88"> IN YOUR PATIENTS WITH SEVERE UNCONTROLLED ASTHMA </a> <a title="EMJ 4.1 2019 page 89" href="http://viewer.zmags.com/publication/137491e8?page=89"> Partial Clinical Remission of Type 1 Diabetes Mel</a> <a title="EMJ 4.1 2019 page 90" href="http://viewer.zmags.com/publication/137491e8?page=90"> and‘paediatrics type 1 diabetes’. Nine paper</a> <a title="EMJ 4.1 2019 page 91" href="http://viewer.zmags.com/publication/137491e8?page=91"> Mechanisms of Non-Remission The molecular mechani</a> <a title="EMJ 4.1 2019 page 92" href="http://viewer.zmags.com/publication/137491e8?page=92"> on a simple and user-friendly tool for the</a> <a title="EMJ 4.1 2019 page 93" href="http://viewer.zmags.com/publication/137491e8?page=93"> early detection of PCR, but is more specific for t</a> <a title="EMJ 4.1 2019 page 94" href="http://viewer.zmags.com/publication/137491e8?page=94"> another study in children and adolescents wi</a> <a title="EMJ 4.1 2019 page 95" href="http://viewer.zmags.com/publication/137491e8?page=95"> The first step to address this came from a recent </a> <a title="EMJ 4.1 2019 page 96" href="http://viewer.zmags.com/publication/137491e8?page=96"> to recommend the initiation of lipid monitoring a</a> <a title="EMJ 4.1 2019 page 97" href="http://viewer.zmags.com/publication/137491e8?page=97"> 28. Scholin A et al.; Diabetes Incidence </a> <a title="EMJ 4.1 2019 page 98" href="http://viewer.zmags.com/publication/137491e8?page=98"> a honeymoon phase had </a> <a title="EMJ 4.1 2019 page 99" href="http://viewer.zmags.com/publication/137491e8?page=99"> Available now. EMJ provides i</a> <a title="EMJ 4.1 2019 page 100" href="http://viewer.zmags.com/publication/137491e8?page=100"> MET Inhibition in Non-Small Cell Lung Cancer Au</a> <a title="EMJ 4.1 2019 page 101" href="http://viewer.zmags.com/publication/137491e8?page=101"> biological activity, and a tail on the C-terminal</a> <a title="EMJ 4.1 2019 page 102" href="http://viewer.zmags.com/publication/137491e8?page=102"> Different signal transduction pathways activated </a> <a title="EMJ 4.1 2019 page 103" href="http://viewer.zmags.com/publication/137491e8?page=103"> trials investigating the therapeutic efficacy of </a> <a title="EMJ 4.1 2019 page 104" href="http://viewer.zmags.com/publication/137491e8?page=104"> Table 1: Summary of IC50 data from available lite</a> <a title="EMJ 4.1 2019 page 105" href="http://viewer.zmags.com/publication/137491e8?page=105"> was investigated in Asian patients with</a> <a title="EMJ 4.1 2019 page 106" href="http://viewer.zmags.com/publication/137491e8?page=106"> Cabozantinib Cabozantinib is a multikinase Type I</a> <a title="EMJ 4.1 2019 page 107" href="http://viewer.zmags.com/publication/137491e8?page=107"> fragment (Fab) fused to a complete constant domai</a> <a title="EMJ 4.1 2019 page 108" href="http://viewer.zmags.com/publication/137491e8?page=108"> due to its antineoplastic activity.85 Based </a> <a title="EMJ 4.1 2019 page 109" href="http://viewer.zmags.com/publication/137491e8?page=109"> transformed cells. J Biol Chem. 2000;275(12):8806</a> <a title="EMJ 4.1 2019 page 110" href="http://viewer.zmags.com/publication/137491e8?page=110"> patients (pts) with advanced cMET+ 60. non-</a> <a title="EMJ 4.1 2019 page 111" href="http://viewer.zmags.com/publication/137491e8?page=111"> hepatocyte growth factor (HGF) inhibitory monoclo</a> <a title="EMJ 4.1 2019 page 112" href="http://viewer.zmags.com/publication/137491e8?page=112"> What's New HIV Undetectable in a UK Pa</a> <a title="EMJ 4.1 2019 page 113" href="http://viewer.zmags.com/publication/137491e8?page=113"> Painting a Detailed Picture of Acute Myeloid Leuk</a> <a title="EMJ 4.1 2019 page 114" href="http://viewer.zmags.com/publication/137491e8?page=114"> What's New Sexual Dysfunction: Q</a> <a title="EMJ 4.1 2019 page 115" href="http://viewer.zmags.com/publication/137491e8?page=115"> The Double Life of p53, the Guardian of the Genom</a> <a title="EMJ 4.1 2019 page 116" href="http://viewer.zmags.com/publication/137491e8?page=116"> Never miss an update again. 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