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<br /> HEPATOLOGY<br /> ISSN 2053-4221 Vol 5.1 • June 2017 • europeanmedical-journal.com<br /> INSIDE<br /> Review of<br /> ILC 2017<br /> Amsterdam, Netherlands<br /> CONTENTS<br /> EDITORIAL BOARD...................................................................................................................................... 4<br /> CONGRESS REVIEW..................................................................................................................................... 12<br /> • Review of the International Liver Congress™ 2017, held in Amsterdam, Netherlands,<br /> 19th–23rd April 2017<br /> • INTERVIEWS WITH EMJ HEPATOLOGY EDITORIAL BOARD........................................................ 30<br /> SYMPOSIUM REVIEW<br /> • A DISCUSSION ON THE MANAGEMENT OF WILSON DISEASE...............................................<a title="EMJ Hepatology 5.1 2017 page 1" href="http://viewer.zmags.com/publication/180903a3?page=1"> HEPATOLOGY ISSN 2053-4221 </a> <a title="EMJ Hepatology 5.1 2017 page 2" href="http://viewer.zmags.com/publication/180903a3?page=2"> CONTENTS EDITORIAL BOARD.......................</a> <a title="EMJ Hepatology 5.1 2017 page 3" href="http://viewer.zmags.com/publication/180903a3?page=3"> HEPATOLOGY ARTICLES • EDITOR’S PICK: HEPATOCEL</a> <a title="EMJ Hepatology 5.1 2017 page 4" href="http://viewer.zmags.com/publication/180903a3?page=4"> EDITORIAL BOARD EDITOR-IN-CHIEF Prof Markus Pec</a> <a title="EMJ Hepatology 5.1 2017 page 5" href="http://viewer.zmags.com/publication/180903a3?page=5"> HEPATOLOGY AIMS AND SCOPE • The European </a> <a title="EMJ Hepatology 5.1 2017 page 6" href="http://viewer.zmags.com/publication/180903a3?page=6"> HEPATOLOGY 5.1 JUNE 2017 Director Spencer Gore </a> <a title="EMJ Hepatology 5.1 2017 page 7" href="http://viewer.zmags.com/publication/180903a3?page=7"> Welcome I would like to bid everyone a warm we</a> <a title="EMJ Hepatology 5.1 2017 page 8" href="http://viewer.zmags.com/publication/180903a3?page=8"> europeanmedical-journal.com EUROPEAN UNION Invest</a> <a title="EMJ Hepatology 5.1 2017 page 9" href="http://viewer.zmags.com/publication/180903a3?page=9"> Foreword </a> <a title="EMJ Hepatology 5.1 2017 page 10" href="http://viewer.zmags.com/publication/180903a3?page=10"> Available Now E</a> <a title="EMJ Hepatology 5.1 2017 page 11" href="http://viewer.zmags.com/publication/180903a3?page=11"> FEATURES Revolutionising Healthcare by Empowering</a> <a title="EMJ Hepatology 5.1 2017 page 12" href="http://viewer.zmags.com/publication/180903a3?page=12"> 12 HEPATOLOGY • June 2017 </a> <a title="EMJ Hepatology 5.1 2017 page 13" href="http://viewer.zmags.com/publication/180903a3?page=13"> ILC ANNUAL CONGRESS 2017 </a> <a title="EMJ Hepatology 5.1 2017 page 14" href="http://viewer.zmags.com/publication/180903a3?page=14"> study of the liver. Among these recognition award</a> <a title="EMJ Hepatology 5.1 2017 page 15" href="http://viewer.zmags.com/publication/180903a3?page=15"> Potential Advance in Treatment for Paediatric Cho</a> <a title="EMJ Hepatology 5.1 2017 page 16" href="http://viewer.zmags.com/publication/180903a3?page=16"> issue in chronic cholestatic diseases. Currently,</a> <a title="EMJ Hepatology 5.1 2017 page 17" href="http://viewer.zmags.com/publication/180903a3?page=17"> The results from this study demonstrate that in p</a> <a title="EMJ Hepatology 5.1 2017 page 18" href="http://viewer.zmags.com/publication/180903a3?page=18"> The results of this study can help us identify wh</a> <a title="EMJ Hepatology 5.1 2017 page 19" href="http://viewer.zmags.com/publication/180903a3?page=19"> EASL Governing Board Member, Prof Philip New</a> <a title="EMJ Hepatology 5.1 2017 page 20" href="http://viewer.zmags.com/publication/180903a3?page=20"> Nivolumab: Acceptable Safety and Promising Effica</a> <a title="EMJ Hepatology 5.1 2017 page 21" href="http://viewer.zmags.com/publication/180903a3?page=21"> The ANSWER study used a control trial of 440 rand</a> <a title="EMJ Hepatology 5.1 2017 page 22" href="http://viewer.zmags.com/publication/180903a3?page=22"> Our research reveals that a country’s climate and</a> <a title="EMJ Hepatology 5.1 2017 page 23" href="http://viewer.zmags.com/publication/180903a3?page=23"> Successful Results of Trial of Fibrate Therapy in</a> <a title="EMJ Hepatology 5.1 2017 page 24" href="http://viewer.zmags.com/publication/180903a3?page=24"> PBC is a rare, chronic, autoimmune disease that c</a> <a title="EMJ Hepatology 5.1 2017 page 25" href="http://viewer.zmags.com/publication/180903a3?page=25"> transplant. Patients who contracted HCV at birth </a> <a title="EMJ Hepatology 5.1 2017 page 26" href="http://viewer.zmags.com/publication/180903a3?page=26"> Optimism for Treatment of Challenging Hepatitis C</a> <a title="EMJ Hepatology 5.1 2017 page 27" href="http://viewer.zmags.com/publication/180903a3?page=27"> Following completion of 12 weeks of treatment, 99</a> <a title="EMJ Hepatology 5.1 2017 page 28" href="http://viewer.zmags.com/publication/180903a3?page=28"> HEV infection is often asymptomatic, so blood don</a> <a title="EMJ Hepatology 5.1 2017 page 29" href="http://viewer.zmags.com/publication/180903a3?page=29"> New Clinical Practice Guidelines Unveiled for Liv</a> <a title="EMJ Hepatology 5.1 2017 page 30" href="http://viewer.zmags.com/publication/180903a3?page=30"> Markus Peck-Radosavljevic Professor of Medicine </a> <a title="EMJ Hepatology 5.1 2017 page 31" href="http://viewer.zmags.com/publication/180903a3?page=31"> Q: Have there been any changes in the prevalence </a> <a title="EMJ Hepatology 5.1 2017 page 32" href="http://viewer.zmags.com/publication/180903a3?page=32"> Omar Sued Clinical Research Director, Fundación </a> <a title="EMJ Hepatology 5.1 2017 page 33" href="http://viewer.zmags.com/publication/180903a3?page=33"> A: The guidelines are very important for countrie</a> <a title="EMJ Hepatology 5.1 2017 page 34" href="http://viewer.zmags.com/publication/180903a3?page=34"> Heidar Sharafi Molecular Hepatologist; Research D</a> <a title="EMJ Hepatology 5.1 2017 page 35" href="http://viewer.zmags.com/publication/180903a3?page=35"> the help of our network of research centres, util</a> <a title="EMJ Hepatology 5.1 2017 page 36" href="http://viewer.zmags.com/publication/180903a3?page=36"> of hepatology has evolved rapidly during the past</a> <a title="EMJ Hepatology 5.1 2017 page 37" href="http://viewer.zmags.com/publication/180903a3?page=37"> research projects. iii) Research: about half of m</a> <a title="EMJ Hepatology 5.1 2017 page 38" href="http://viewer.zmags.com/publication/180903a3?page=38"> Q: This April’s European Association for the Stud</a> <a title="EMJ Hepatology 5.1 2017 page 39" href="http://viewer.zmags.com/publication/180903a3?page=39"> Watch our exclusive interview from the 52nd ILC </a> <a title="EMJ Hepatology 5.1 2017 page 40" href="http://viewer.zmags.com/publication/180903a3?page=40"> A DISCUSSION ON THE MANAGEMENT O</a> <a title="EMJ Hepatology 5.1 2017 page 41" href="http://viewer.zmags.com/publication/180903a3?page=41"> showed the importance of patients remaining with </a> <a title="EMJ Hepatology 5.1 2017 page 42" href="http://viewer.zmags.com/publication/180903a3?page=42"> A problem for assessing treatment efficacy in WD,</a> <a title="EMJ Hepatology 5.1 2017 page 43" href="http://viewer.zmags.com/publication/180903a3?page=43"> Dr Hirschfield explained that, when consideri</a> <a title="EMJ Hepatology 5.1 2017 page 44" href="http://viewer.zmags.com/publication/180903a3?page=44"> enzymes (AST: 67; ALT: 71) and on ultrasound was </a> <a title="EMJ Hepatology 5.1 2017 page 45" href="http://viewer.zmags.com/publication/180903a3?page=45"> Such delays, stressed Prof Dhawan, underline the </a> <a title="EMJ Hepatology 5.1 2017 page 46" href="http://viewer.zmags.com/publication/180903a3?page=46"> the Heidelberg Vienna cohort study, a retrospecti</a> <a title="EMJ Hepatology 5.1 2017 page 47" href="http://viewer.zmags.com/publication/180903a3?page=47"> REFERENCES 1. Ferenci P. Phenotype-geno</a> <a title="EMJ Hepatology 5.1 2017 page 48" href="http://viewer.zmags.com/publication/180903a3?page=48"> Abstract Reviews THE IMPORTANCE OF CIVIL SOCIETY </a> <a title="EMJ Hepatology 5.1 2017 page 49" href="http://viewer.zmags.com/publication/180903a3?page=49"> ILC 2017 In a ‘Civil Society Declaration on the </a> <a title="EMJ Hepatology 5.1 2017 page 50" href="http://viewer.zmags.com/publication/180903a3?page=50"> Abstract Reviews in the simvastatin group develo</a> <a title="EMJ Hepatology 5.1 2017 page 51" href="http://viewer.zmags.com/publication/180903a3?page=51"> ILC 2017 linearity, negligible bias, and high pr</a> <a title="EMJ Hepatology 5.1 2017 page 52" href="http://viewer.zmags.com/publication/180903a3?page=52"> Abstract Reviews ADENOSINE 2A RECEPTOR STIMULAT</a> <a title="EMJ Hepatology 5.1 2017 page 53" href="http://viewer.zmags.com/publication/180903a3?page=53"> ILC 2017 These data offer novel insights</a> <a title="EMJ Hepatology 5.1 2017 page 54" href="http://viewer.zmags.com/publication/180903a3?page=54"> Abstract Reviews clinically significant varices d</a> <a title="EMJ Hepatology 5.1 2017 page 55" href="http://viewer.zmags.com/publication/180903a3?page=55"> ILC 2017 A high waist circumference to BMI ratio</a> <a title="EMJ Hepatology 5.1 2017 page 56" href="http://viewer.zmags.com/publication/180903a3?page=56"> Abstract Reviews By the nationwide analysis </a> <a title="EMJ Hepatology 5.1 2017 page 57" href="http://viewer.zmags.com/publication/180903a3?page=57"> ILC 2017 with increased survival in PSC. The mos</a> <a title="EMJ Hepatology 5.1 2017 page 58" href="http://viewer.zmags.com/publication/180903a3?page=58"> Abstract Reviews HEV infection has been associat</a> <a title="EMJ Hepatology 5.1 2017 page 59" href="http://viewer.zmags.com/publication/180903a3?page=59"> ILC 2017 CLINICAL HEPATOCYTE CELL THERAPY:</a> <a title="EMJ Hepatology 5.1 2017 page 60" href="http://viewer.zmags.com/publication/180903a3?page=60"> Abstract Reviews Diagnosis of rejection is p</a> <a title="EMJ Hepatology 5.1 2017 page 61" href="http://viewer.zmags.com/publication/180903a3?page=61"> ILC 2017 in the European directive 55/2013/E</a> <a title="EMJ Hepatology 5.1 2017 page 62" href="http://viewer.zmags.com/publication/180903a3?page=62"> Abstract Reviews Information System ( ‘the IMI R</a> <a title="EMJ Hepatology 5.1 2017 page 63" href="http://viewer.zmags.com/publication/180903a3?page=63"> ILC 2017 care part is completed by nurses, which</a> <a title="EMJ Hepatology 5.1 2017 page 64" href="http://viewer.zmags.com/publication/180903a3?page=64"> Abstract Reviews DIAGNOSIS AND STAGE-DEPENDENT</a> <a title="EMJ Hepatology 5.1 2017 page 65" href="http://viewer.zmags.com/publication/180903a3?page=65"> Would you like to write for the EMJ blog? Interac</a> <a title="EMJ Hepatology 5.1 2017 page 66" href="http://viewer.zmags.com/publication/180903a3?page=66"> SPECIAL POSTER FEATURE AMERICAN ASSOCIAT</a> <a title="EMJ Hepatology 5.1 2017 page 67" href="http://viewer.zmags.com/publication/180903a3?page=67"> and 70 (3.6%) to HCV Ab- LT recipients (+/-). Com</a> <a title="EMJ Hepatology 5.1 2017 page 68" href="http://viewer.zmags.com/publication/180903a3?page=68"> aminotransferase (ALT) levels occur in most patie</a> <a title="EMJ Hepatology 5.1 2017 page 69" href="http://viewer.zmags.com/publication/180903a3?page=69"> Variation in Demographics and Comorbidities in He</a> <a title="EMJ Hepatology 5.1 2017 page 70" href="http://viewer.zmags.com/publication/180903a3?page=70"> immunosuppressive therapy was maintained, and pat</a> <a title="EMJ Hepatology 5.1 2017 page 71" href="http://viewer.zmags.com/publication/180903a3?page=71"> 2013), or ‘DAA’ (2014–2015). Annual standardised </a> <a title="EMJ Hepatology 5.1 2017 page 72" href="http://viewer.zmags.com/publication/180903a3?page=72"> BETA-BLOCKERS IN PREVENTION OF DEVELOPMENT OF VAR</a> <a title="EMJ Hepatology 5.1 2017 page 73" href="http://viewer.zmags.com/publication/180903a3?page=73"> follow-up, although there was no difference </a> <a title="EMJ Hepatology 5.1 2017 page 74" href="http://viewer.zmags.com/publication/180903a3?page=74"> the progression of varices should encourage furth</a> <a title="EMJ Hepatology 5.1 2017 page 75" href="http://viewer.zmags.com/publication/180903a3?page=75"> EDITOR’S PICK Our Editor’s Pick for </a> <a title="EMJ Hepatology 5.1 2017 page 76" href="http://viewer.zmags.com/publication/180903a3?page=76"> probable cause for this is the different aetiolog</a> <a title="EMJ Hepatology 5.1 2017 page 77" href="http://viewer.zmags.com/publication/180903a3?page=77"> Homozygosity of the C282Y mutation on the H</a> <a title="EMJ Hepatology 5.1 2017 page 78" href="http://viewer.zmags.com/publication/180903a3?page=78"> eicosapentaenoic acid, docosapentaenoic acid, and</a> <a title="EMJ Hepatology 5.1 2017 page 79" href="http://viewer.zmags.com/publication/180903a3?page=79"> kinase ligands is significant in HCC development.3</a> <a title="EMJ Hepatology 5.1 2017 page 80" href="http://viewer.zmags.com/publication/180903a3?page=80"> REFERENCES 1. Jemal A et al. Global cancer stati</a> <a title="EMJ Hepatology 5.1 2017 page 81" href="http://viewer.zmags.com/publication/180903a3?page=81"> HEPATOCELLULAR CARCINOMA. PART 2: CLINICAL PRESE</a> <a title="EMJ Hepatology 5.1 2017 page 82" href="http://viewer.zmags.com/publication/180903a3?page=82"> Embryonic Antigen Alpha fetoprotein (AFP) is a gl</a> <a title="EMJ Hepatology 5.1 2017 page 83" href="http://viewer.zmags.com/publication/180903a3?page=83"> It has an immunosuppressive effect by inhibiting </a> <a title="EMJ Hepatology 5.1 2017 page 84" href="http://viewer.zmags.com/publication/180903a3?page=84"> Hepatic nodule <1 cm US follow-up at 3 months Sta</a> <a title="EMJ Hepatology 5.1 2017 page 85" href="http://viewer.zmags.com/publication/180903a3?page=85"> Table 1: Barcelona Clinic Liver Cancer staging cl</a> <a title="EMJ Hepatology 5.1 2017 page 86" href="http://viewer.zmags.com/publication/180903a3?page=86"> early, early, intermediate, advanced, and termina</a> <a title="EMJ Hepatology 5.1 2017 page 87" href="http://viewer.zmags.com/publication/180903a3?page=87"> Table 4: Cancer of the Liver Italian Program scor</a> <a title="EMJ Hepatology 5.1 2017 page 88" href="http://viewer.zmags.com/publication/180903a3?page=88"> a systematic review and meta-analysis. Ann Intern</a> <a title="EMJ Hepatology 5.1 2017 page 89" href="http://viewer.zmags.com/publication/180903a3?page=89"> HEPATOCELLULAR CARCINOMA. PART 3: SURGICAL AND </a> <a title="EMJ Hepatology 5.1 2017 page 90" href="http://viewer.zmags.com/publication/180903a3?page=90"> method is based on computed tomography (CT) imagi</a> <a title="EMJ Hepatology 5.1 2017 page 91" href="http://viewer.zmags.com/publication/180903a3?page=91"> Percutaneous Ethanol Injection Percutaneous ethan</a> <a title="EMJ Hepatology 5.1 2017 page 92" href="http://viewer.zmags.com/publication/180903a3?page=92"> Child–Pugh Class A or B with MC fulfilled, the 5-y</a> <a title="EMJ Hepatology 5.1 2017 page 93" href="http://viewer.zmags.com/publication/180903a3?page=93"> Contraindications to TACE include: Child–Pugh</a> <a title="EMJ Hepatology 5.1 2017 page 94" href="http://viewer.zmags.com/publication/180903a3?page=94"> given but no favourable outcome was seen and the </a> <a title="EMJ Hepatology 5.1 2017 page 95" href="http://viewer.zmags.com/publication/180903a3?page=95"> of life in these patients but does not improve li</a> <a title="EMJ Hepatology 5.1 2017 page 96" href="http://viewer.zmags.com/publication/180903a3?page=96"> carcinoma. J Hepatol. 2012;56(6):1336-42. 38. Sie</a> <a title="EMJ Hepatology 5.1 2017 page 97" href="http://viewer.zmags.com/publication/180903a3?page=97"> A LOOK AT PLATELET COUNT IN CHRONIC HEPATITIS C </a> <a title="EMJ Hepatology 5.1 2017 page 98" href="http://viewer.zmags.com/publication/180903a3?page=98"> occurs after a latency period of 5 days and reach</a> <a title="EMJ Hepatology 5.1 2017 page 99" href="http://viewer.zmags.com/publication/180903a3?page=99"> only a few reports and one observational study up</a> <a title="EMJ Hepatology 5.1 2017 page 100" href="http://viewer.zmags.com/publication/180903a3?page=100"> Thus, although TPO may not have direct effects on</a> <a title="EMJ Hepatology 5.1 2017 page 101" href="http://viewer.zmags.com/publication/180903a3?page=101"> Tofacitinib (a pan-JAK inhibitor)54 could be</a> <a title="EMJ Hepatology 5.1 2017 page 102" href="http://viewer.zmags.com/publication/180903a3?page=102"> REFERENCES 1. Deutsch VR, Tomer A. Advances</a> <a title="EMJ Hepatology 5.1 2017 page 103" href="http://viewer.zmags.com/publication/180903a3?page=103"> constitutively activates STAT-3 via oxid</a> <a title="EMJ Hepatology 5.1 2017 page 104" href="http://viewer.zmags.com/publication/180903a3?page=104"> EUROPEAN MEDICAL JOURNAL provides influential arti</a> <a title="EMJ Hepatology 5.1 2017 page 105" href="http://viewer.zmags.com/publication/180903a3?page=105"> Buyer’s Guide • ABBVIE • ADVANCED BIOLOGICAL</a> <a title="EMJ Hepatology 5.1 2017 page 106" href="http://viewer.zmags.com/publication/180903a3?page=106"> UPCOMING EVENTS 7th International Tehran Hepatiti</a> <a title="EMJ Hepatology 5.1 2017 page 107" href="http://viewer.zmags.com/publication/180903a3?page=107"> HEPATOLOGY European Association for the Study of </a> <a title="EMJ Hepatology 5.1 2017 page 108" href="http://viewer.zmags.com/publication/180903a3?page=108"> SUBSCRIBE TO RECEIVE THE LATEST PUBLICATIONS, NEW</a>