<br />
HEPATOLOGY<br />
Alexion supplement • emjreviews.com<br />
INSIDE<br />
The Role of Sebelipase Alfa<br />
in Treating Lysosomal Acid<br />
Lipase Deficiency (LAL-D)<br />
THE ROLE OF SEBELIPASE ALFA IN TREATING<br />
LYSOSOMAL ACID LIPASE DEFICIENCY (LAL-D)<br />
Summary of presentations from the Alexion-Sponsored<br />
Educators Forum on LAL-D, held in Frankfurt, Germany,<br />
on 29th and 30th October 2015<br />
Speakers<br />
Florian Abel,1 Barbara K. Burton,2 Brett Billmeyer3<br />
1. Medical Affairs Europe, Middle-East, Africa, Asia-Pacific, Alexion Pharmaceuticals<br />
2. Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA<br />
3. Afton, Minnesota, USA<br />
Disclosure: Dr Abel is a full-time employee of Alexion Pharmaceuticals. In the past 3 years, he has also<br />
been employed by Synageva BioPharma and Daiichi Sankyo Europe. Prof Burton has received <a title="EMJ Hepatol. 2016 Suppl 3 page 1" href="http://viewer.zmags.com/publication/24a55262?page=1"> HEPATOLOGY Alexion supplement • emjreviews.com </a>
<a title="EMJ Hepatol. 2016 Suppl 3 page 2" href="http://viewer.zmags.com/publication/24a55262?page=2"> THE ROLE OF SEBELIPASE ALFA IN TREATING LYSOSOMAL</a>
<a title="EMJ Hepatol. 2016 Suppl 3 page 3" href="http://viewer.zmags.com/publication/24a55262?page=3"> Lysosomal Acid Lipase Deficiency: A Progressive Di</a>
<a title="EMJ Hepatol. 2016 Suppl 3 page 4" href="http://viewer.zmags.com/publication/24a55262?page=4"> LIVER ABNORMALITIES HEPATIC STEATOSIS (microvesic</a>
<a title="EMJ Hepatol. 2016 Suppl 3 page 5" href="http://viewer.zmags.com/publication/24a55262?page=5"> abnormalities (87% of patients).1 In the liver, L</a>
<a title="EMJ Hepatol. 2016 Suppl 3 page 6" href="http://viewer.zmags.com/publication/24a55262?page=6"> Sebelipase alfa was approved in the Europea</a>
<a title="EMJ Hepatol. 2016 Suppl 3 page 7" href="http://viewer.zmags.com/publication/24a55262?page=7"> Key results: infants (LAL-CL03)15 LAL-CL03 was </a>
<a title="EMJ Hepatol. 2016 Suppl 3 page 8" href="http://viewer.zmags.com/publication/24a55262?page=8"> The implications of this study are</a>
<a title="EMJ Hepatol. 2016 Suppl 3 page 9" href="http://viewer.zmags.com/publication/24a55262?page=9"> Med. 2015. doi: 10.1038/gim.2015.108. [Epub</a>