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<br /> ARCHIVE<br /> 2<br /> VOLUME 112 NUMBER 1 JANUARY 2017<br /> www.nature.com/ajg<br /> official publication of the american college of gastroenterology<br /> LEADING ARTICLES OF THE MONTH<br /> Practice Guidelines<br /> 18 ACG Clinical Guideline: Evaluation of Abnormal Liver Chemistries CME<br /> Paul Y. Kwo, Stanley M. Cohen and Joseph K. Lim<br /> 37 Recommendations on Fecal Immunochemical Testing to Screen for<br /> Colorectal Neoplasia: A Consensus Statement by the US<br /> Multi-Society Task Force on Colorectal Cancer<br /> Douglas J. Robertson, Jeffrey K. Lee, C. Richard Boland, Jason A. Dominitz,<br /> Francis M. Giardiello, David A. Johnson, Tonya Kaltenbach,<br /> David Lieberman, Theodore R. Levin and Douglas K. Rex<br /> Clinical and Systematic Reviews<br /> 65 Screening for Celiac Disease in Irritable Bowel Syndrome:<br /> An Upd<a title="AJG_Vol.113.No1. page 1" href="http://viewer.zmags.com/publication/2b438029?page=1"> ARCHIVE 2 VOLUME 112 NUMBER 1 JANUARY 2017 www.</a> <a title="AJG_Vol.113.No1. page 2" href="http://viewer.zmags.com/publication/2b438029?page=2"> VOLUME 113 NUMBER 1 JANUARY 2018 www.nature.com/a</a> <a title="AJG_Vol.113.No1. page 3" href="http://viewer.zmags.com/publication/2b438029?page=3"> INDICATIONS Adult Ulcerative Colitis (UC) ENTYVIO</a> <a title="AJG_Vol.113.No1. page 4" href="http://viewer.zmags.com/publication/2b438029?page=4"> FOR ADULTS WITH MODERATELY TO SEVERELY ACTIVE UC </a> <a title="AJG_Vol.113.No1. page 5" href="http://viewer.zmags.com/publication/2b438029?page=5"> BRIEF SUMMARY OF FULL PRESCRIBING INFORMATION ENT</a> <a title="AJG_Vol.113.No1. page 6" href="http://viewer.zmags.com/publication/2b438029?page=6"> Table 1. Adverse Reactions in ≥3% of ENTYVIO-trea</a> <a title="AJG_Vol.113.No1. page 7" href="http://viewer.zmags.com/publication/2b438029?page=7"> by several factors, including sample handling, ti</a> <a title="AJG_Vol.113.No1. page 8" href="http://viewer.zmags.com/publication/2b438029?page=8"> www.nature.com/ajg The American Journal o</a> <a title="AJG_Vol.113.No1. page 9" href="http://viewer.zmags.com/publication/2b438029?page=9"> IMPORTANT SAFETY INFORMATION WARNING: RISK OF SE</a> <a title="AJG_Vol.113.No1. page 10" href="http://viewer.zmags.com/publication/2b438029?page=10"> FOR ADULTS WITH CHRONIC IDIOPATHIC CONSTIPATION (</a> <a title="AJG_Vol.113.No1. page 11" href="http://viewer.zmags.com/publication/2b438029?page=11"> Trulance™ (plecanatide) tablets, for oral use Rx </a> <a title="AJG_Vol.113.No1. page 12" href="http://viewer.zmags.com/publication/2b438029?page=12"> ACG MOBILE:ACCESS KEY RESOURCES </a> <a title="AJG_Vol.113.No1. page 13" href="http://viewer.zmags.com/publication/2b438029?page=13"> official publication of the american college</a> <a title="AJG_Vol.113.No1. page 14" href="http://viewer.zmags.com/publication/2b438029?page=14"> RECOMMEND THE BEST WITH NEXIUM® 24HR Nexium® 24HR</a> <a title="AJG_Vol.113.No1. page 15" href="http://viewer.zmags.com/publication/2b438029?page=15"> For first-line constipation therapy, stick with t</a> <a title="AJG_Vol.113.No1. page 16" href="http://viewer.zmags.com/publication/2b438029?page=16"> VOLUME 113 NUMBER 1 JANUARY 2018 www.nature.com/a</a> <a title="AJG_Vol.113.No1. page 17" href="http://viewer.zmags.com/publication/2b438029?page=17"> CONTENTS Numberofsubjects(N=45) 45 42 40 40</a> <a title="AJG_Vol.113.No1. page 18" href="http://viewer.zmags.com/publication/2b438029?page=18"> www.nature.com/ajg Placebo 30 min basel</a> <a title="AJG_Vol.113.No1. page 19" href="http://viewer.zmags.com/publication/2b438029?page=19"> Attend an upcoming 2018 ACG Regional Pos</a> <a title="AJG_Vol.113.No1. page 20" href="http://viewer.zmags.com/publication/2b438029?page=20"> ® Look Below the Surface Molecular Testin</a> <a title="AJG_Vol.113.No1. page 21" href="http://viewer.zmags.com/publication/2b438029?page=21"> e week's best science, from the world's #1 s</a> <a title="AJG_Vol.113.No1. page 22" href="http://viewer.zmags.com/publication/2b438029?page=22"> Accessible. Relevant. Practical. The information</a> <a title="AJG_Vol.113.No1. page 23" href="http://viewer.zmags.com/publication/2b438029?page=23"> 65 Years of GI Endoscopy Innovation in One Powerf</a> <a title="AJG_Vol.113.No1. page 24" href="http://viewer.zmags.com/publication/2b438029?page=24"> THE RED SECTION 1 see related editorial o</a> <a title="AJG_Vol.113.No1. page 25" href="http://viewer.zmags.com/publication/2b438029?page=25"> 2 THE RED SECTION Gastr</a> <a title="AJG_Vol.113.No1. page 26" href="http://viewer.zmags.com/publication/2b438029?page=26"> of Life measurements improve in the DAA era follo</a> <a title="AJG_Vol.113.No1. page 27" href="http://viewer.zmags.com/publication/2b438029?page=27"> 4 THE RED SECTION Potential competing int</a> <a title="AJG_Vol.113.No1. page 28" href="http://viewer.zmags.com/publication/2b438029?page=28"> THE RED SECTION 5 see related editorial o</a> <a title="AJG_Vol.113.No1. page 29" href="http://viewer.zmags.com/publication/2b438029?page=29"> 6 THE RED SECTION </a> <a title="AJG_Vol.113.No1. page 30" href="http://viewer.zmags.com/publication/2b438029?page=30"> potential harms. For the patient in our scenario,</a> <a title="AJG_Vol.113.No1. page 31" href="http://viewer.zmags.com/publication/2b438029?page=31"> 8 THE RED SECTION IN MY OWN VOICE October 8,</a> <a title="AJG_Vol.113.No1. page 32" href="http://viewer.zmags.com/publication/2b438029?page=32"> Figure 1. A standard ostomy pouch with the ostom-</a> <a title="AJG_Vol.113.No1. page 33" href="http://viewer.zmags.com/publication/2b438029?page=33"> 10 THE RED SECTION IN MY OWN VOICE Figure 3.</a> <a title="AJG_Vol.113.No1. page 34" href="http://viewer.zmags.com/publication/2b438029?page=34"> Springer Nature </a> <a title="AJG_Vol.113.No1. page 35" href="http://viewer.zmags.com/publication/2b438029?page=35"> 12 THE RED SECTION Video of the Month Cann</a> <a title="AJG_Vol.113.No1. page 36" href="http://viewer.zmags.com/publication/2b438029?page=36"> CLINICAL AND SYSTEMATIC REVIEWS 13 CME “W</a> <a title="AJG_Vol.113.No1. page 37" href="http://viewer.zmags.com/publication/2b438029?page=37"> 14 Gupta et al. REVIEW METHODS A systematic</a> <a title="AJG_Vol.113.No1. page 38" href="http://viewer.zmags.com/publication/2b438029?page=38"> “Weekend Effect” in Upper GI Hemorrhage 15 </a> <a title="AJG_Vol.113.No1. page 39" href="http://viewer.zmags.com/publication/2b438029?page=39"> 16 Gupta et al. Table 2. GRADE evidence profi</a> <a title="AJG_Vol.113.No1. page 40" href="http://viewer.zmags.com/publication/2b438029?page=40"> “Weekend Effect” in Upper GI Hemorrhage 17 </a> <a title="AJG_Vol.113.No1. page 41" href="http://viewer.zmags.com/publication/2b438029?page=41"> 18 Gupta et al. Weekend W</a> <a title="AJG_Vol.113.No1. page 42" href="http://viewer.zmags.com/publication/2b438029?page=42"> “Weekend Effect” in Upper GI Hemorrhage 19 </a> <a title="AJG_Vol.113.No1. page 43" href="http://viewer.zmags.com/publication/2b438029?page=43"> 20 Gupta et al. REVIEW to the fact that sev</a> <a title="AJG_Vol.113.No1. page 44" href="http://viewer.zmags.com/publication/2b438029?page=44"> portal hypertension: post hoc analysis of </a> <a title="AJG_Vol.113.No1. page 45" href="http://viewer.zmags.com/publication/2b438029?page=45"> 22 CONTINUING MEDICAL EDUCATION CME CONT</a> <a title="AJG_Vol.113.No1. page 46" href="http://viewer.zmags.com/publication/2b438029?page=46"> ORIGINAL CONTRIBUTIONS 23 see related edit</a> <a title="AJG_Vol.113.No1. page 47" href="http://viewer.zmags.com/publication/2b438029?page=47"> 24 Yadlapati et al. ESOPHAGUS In addition, </a> <a title="AJG_Vol.113.No1. page 48" href="http://viewer.zmags.com/publication/2b438029?page=48"> Weight Loss and Symptom Improvement in Obesity an</a> <a title="AJG_Vol.113.No1. page 49" href="http://viewer.zmags.com/publication/2b438029?page=49"> 26 Yadlapati et al. ESOPHAGUS Score 14 12 </a> <a title="AJG_Vol.113.No1. page 50" href="http://viewer.zmags.com/publication/2b438029?page=50"> Weight Loss and Symptom Improvement in Obesity an</a> <a title="AJG_Vol.113.No1. page 51" href="http://viewer.zmags.com/publication/2b438029?page=51"> 28 Yadlapati et al. ESOPHAGUS The epidemi</a> <a title="AJG_Vol.113.No1. page 52" href="http://viewer.zmags.com/publication/2b438029?page=52"> participants positively reporting outcomes, inher</a> <a title="AJG_Vol.113.No1. page 53" href="http://viewer.zmags.com/publication/2b438029?page=53"> 30 Yadlapati et al. ESOPHAGUS 8. Yadlapati</a> <a title="AJG_Vol.113.No1. page 54" href="http://viewer.zmags.com/publication/2b438029?page=54"> ORIGINAL CONTRIBUTIONS 31 see related edi</a> <a title="AJG_Vol.113.No1. page 55" href="http://viewer.zmags.com/publication/2b438029?page=55"> 32 Yadlapati et al. ESOPHAGUS perceive trou</a> <a title="AJG_Vol.113.No1. page 56" href="http://viewer.zmags.com/publication/2b438029?page=56"> RESULTS Participants Over the study period, 298 P</a> <a title="AJG_Vol.113.No1. page 57" href="http://viewer.zmags.com/publication/2b438029?page=57"> 34 Yadlapati et al. ESOPHAGUS Table 1. Base</a> <a title="AJG_Vol.113.No1. page 58" href="http://viewer.zmags.com/publication/2b438029?page=58"> Table 2. Assessment of risk factors of abnormal G</a> <a title="AJG_Vol.113.No1. page 59" href="http://viewer.zmags.com/publication/2b438029?page=59"> 36 Yadlapati et al. ESOPHAGUS Table 4. Pred</a> <a title="AJG_Vol.113.No1. page 60" href="http://viewer.zmags.com/publication/2b438029?page=60"> Symptom Perception Among PPI Non-Responder Phenot</a> <a title="AJG_Vol.113.No1. page 61" href="http://viewer.zmags.com/publication/2b438029?page=61"> 38 Yadlapati et al. ESOPHAGUS 2. El-Serag </a> <a title="AJG_Vol.113.No1. page 62" href="http://viewer.zmags.com/publication/2b438029?page=62"> ORIGINAL CONTRIBUTIONS 39 see related edit</a> <a title="AJG_Vol.113.No1. page 63" href="http://viewer.zmags.com/publication/2b438029?page=63"> 40 Taylor et al. STOMACH symptoms appear to</a> <a title="AJG_Vol.113.No1. page 64" href="http://viewer.zmags.com/publication/2b438029?page=64"> Functional Dyspepsia Symptom Diary Development </a> <a title="AJG_Vol.113.No1. page 65" href="http://viewer.zmags.com/publication/2b438029?page=65"> 42 Taylor et al. STOMACH and protocol amend</a> <a title="AJG_Vol.113.No1. page 66" href="http://viewer.zmags.com/publication/2b438029?page=66"> Functional Dyspepsia Symptom Diary Development </a> <a title="AJG_Vol.113.No1. page 67" href="http://viewer.zmags.com/publication/2b438029?page=67"> 44 Taylor et al. regarding the usability </a> <a title="AJG_Vol.113.No1. page 68" href="http://viewer.zmags.com/publication/2b438029?page=68"> Functional Dyspepsia Symptom Diary Development </a> <a title="AJG_Vol.113.No1. page 69" href="http://viewer.zmags.com/publication/2b438029?page=69"> 46 Taylor et al. STOMACH Table 3. Inter-ite</a> <a title="AJG_Vol.113.No1. page 70" href="http://viewer.zmags.com/publication/2b438029?page=70"> Another limitation to the research presented is</a> <a title="AJG_Vol.113.No1. page 71" href="http://viewer.zmags.com/publication/2b438029?page=71"> 48 Taylor et al. STOMACH REFERENCES 1. Tac</a> <a title="AJG_Vol.113.No1. page 72" href="http://viewer.zmags.com/publication/2b438029?page=72"> ORIGINAL CONTRIBUTIONS 49 see related edit</a> <a title="AJG_Vol.113.No1. page 73" href="http://viewer.zmags.com/publication/2b438029?page=73"> 50 Reig et al. LIVER with no pruritus at en</a> <a title="AJG_Vol.113.No1. page 74" href="http://viewer.zmags.com/publication/2b438029?page=74"> Bezafibrate in Primary Biliary Cholangitis 51 </a> <a title="AJG_Vol.113.No1. page 75" href="http://viewer.zmags.com/publication/2b438029?page=75"> 52 Reig et al. LIVER Table 2. Baseline clin</a> <a title="AJG_Vol.113.No1. page 76" href="http://viewer.zmags.com/publication/2b438029?page=76"> Bezafibrate in Primary Biliary Cholangitis 53 </a> <a title="AJG_Vol.113.No1. page 77" href="http://viewer.zmags.com/publication/2b438029?page=77"> 54 Reig et al. LIVER or increased in the 11</a> <a title="AJG_Vol.113.No1. page 78" href="http://viewer.zmags.com/publication/2b438029?page=78"> 6. Kurihara T, Niimi A, Maeda A et al. Bezafibra</a> <a title="AJG_Vol.113.No1. page 79" href="http://viewer.zmags.com/publication/2b438029?page=79"> 56 EDITORIAL see related article on page</a> <a title="AJG_Vol.113.No1. page 80" href="http://viewer.zmags.com/publication/2b438029?page=80"> effective therapy is not yet available. Both the </a> <a title="AJG_Vol.113.No1. page 81" href="http://viewer.zmags.com/publication/2b438029?page=81"> 58 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.113.No1. page 82" href="http://viewer.zmags.com/publication/2b438029?page=82"> mucosal healing, leading to symptom remission, fe</a> <a title="AJG_Vol.113.No1. page 83" href="http://viewer.zmags.com/publication/2b438029?page=83"> 60 Almario et al. a Sample screener </a> <a title="AJG_Vol.113.No1. page 84" href="http://viewer.zmags.com/publication/2b438029?page=84"> Optimizing Selection of Biologics in IBD 61 </a> <a title="AJG_Vol.113.No1. page 85" href="http://viewer.zmags.com/publication/2b438029?page=85"> 62 Almario et al. INFLAMMATORY BOWEL DISEASE</a> <a title="AJG_Vol.113.No1. page 86" href="http://viewer.zmags.com/publication/2b438029?page=86"> Optimizing Selection of Biologics in IBD 63 I</a> <a title="AJG_Vol.113.No1. page 87" href="http://viewer.zmags.com/publication/2b438029?page=87"> 64 Almario et al. INFLAMMATORY BOWEL DISEASE</a> <a title="AJG_Vol.113.No1. page 88" href="http://viewer.zmags.com/publication/2b438029?page=88"> Optimizing Selection of Biologics in IBD 65 </a> <a title="AJG_Vol.113.No1. page 89" href="http://viewer.zmags.com/publication/2b438029?page=89"> 66 Almario et al. INFLAMMATORY BOWEL DISEASE</a> <a title="AJG_Vol.113.No1. page 90" href="http://viewer.zmags.com/publication/2b438029?page=90"> Optimizing Selection of Biologics in IBD 67 </a> <a title="AJG_Vol.113.No1. page 91" href="http://viewer.zmags.com/publication/2b438029?page=91"> 68 Almario et al. INFLAMMATORY BOWEL DISEASE</a> <a title="AJG_Vol.113.No1. page 92" href="http://viewer.zmags.com/publication/2b438029?page=92"> for assessing process of care. However, direct ob</a> <a title="AJG_Vol.113.No1. page 93" href="http://viewer.zmags.com/publication/2b438029?page=93"> 70 Almario et al. INFLAMMATORY BOWEL DISEASE</a> <a title="AJG_Vol.113.No1. page 94" href="http://viewer.zmags.com/publication/2b438029?page=94"> 33. Irvine EJ, Zhou Q, Thompson AK. The Short Inf</a> <a title="AJG_Vol.113.No1. page 95" href="http://viewer.zmags.com/publication/2b438029?page=95"> 72 ORIGINAL CONTRIBUTIONS see related ed</a> <a title="AJG_Vol.113.No1. page 96" href="http://viewer.zmags.com/publication/2b438029?page=96"> prospective cohort study suggest that depressive </a> <a title="AJG_Vol.113.No1. page 97" href="http://viewer.zmags.com/publication/2b438029?page=97"> 74 Kochar et al. INFLAMMATORY BOWEL DISEASE </a> <a title="AJG_Vol.113.No1. page 98" href="http://viewer.zmags.com/publication/2b438029?page=98"> 100% 90% 80% 70% 60% </a> <a title="AJG_Vol.113.No1. page 99" href="http://viewer.zmags.com/publication/2b438029?page=99"> 76 Kochar et al. INFLAMMATORY BOWEL DISEASE </a> <a title="AJG_Vol.113.No1. page 100" href="http://viewer.zmags.com/publication/2b438029?page=100"> Table 4a. Association between gastrointestinal sy</a> <a title="AJG_Vol.113.No1. page 101" href="http://viewer.zmags.com/publication/2b438029?page=101"> 78 Kochar et al. INFLAMMATORY BOWEL DISEASE </a> <a title="AJG_Vol.113.No1. page 102" href="http://viewer.zmags.com/publication/2b438029?page=102"> impaired social functioning and increased </a> <a title="AJG_Vol.113.No1. page 103" href="http://viewer.zmags.com/publication/2b438029?page=103"> 80 ORIGINAL CONTRIBUTIONS see related ed</a> <a title="AJG_Vol.113.No1. page 104" href="http://viewer.zmags.com/publication/2b438029?page=104"> at follow-up. We also aimed to compare a single i</a> <a title="AJG_Vol.113.No1. page 105" href="http://viewer.zmags.com/publication/2b438029?page=105"> 82 Kochar et al. INFLAMMATORY BOWEL DISEASE </a> <a title="AJG_Vol.113.No1. page 106" href="http://viewer.zmags.com/publication/2b438029?page=106"> 100 % Surviving without surgery or hospitalizati</a> <a title="AJG_Vol.113.No1. page 107" href="http://viewer.zmags.com/publication/2b438029?page=107"> 84 Kochar et al. INFLAMMATORY BOWEL DISEASE </a> <a title="AJG_Vol.113.No1. page 108" href="http://viewer.zmags.com/publication/2b438029?page=108"> 13. Long MD, Kappelman MD, Martin CF et al. Risk </a> <a title="AJG_Vol.113.No1. page 109" href="http://viewer.zmags.com/publication/2b438029?page=109"> 86 ORIGINAL CONTRIBUTIONS see related edi</a> <a title="AJG_Vol.113.No1. page 110" href="http://viewer.zmags.com/publication/2b438029?page=110"> FGIDs now comprise 33 distinct clinical entities </a> <a title="AJG_Vol.113.No1. page 111" href="http://viewer.zmags.com/publication/2b438029?page=111"> 88 Aziz et al. FUNCTIONAL GI DISORDERS repr</a> <a title="AJG_Vol.113.No1. page 112" href="http://viewer.zmags.com/publication/2b438029?page=112"> Prevalence and Cumulative Impact of Rome IV-Diagn</a> <a title="AJG_Vol.113.No1. page 113" href="http://viewer.zmags.com/publication/2b438029?page=113"> 90 Aziz et al. FUNCTIONAL GI DISORDERS Tabl</a> <a title="AJG_Vol.113.No1. page 114" href="http://viewer.zmags.com/publication/2b438029?page=114"> Bowel disorders n =1665 (80%) 47.8% 9.</a> <a title="AJG_Vol.113.No1. page 115" href="http://viewer.zmags.com/publication/2b438029?page=115"> 92 Aziz et al. 12 10 8 6 4 </a> <a title="AJG_Vol.113.No1. page 116" href="http://viewer.zmags.com/publication/2b438029?page=116"> Prevalence and Cumulative Impact of Rome IV-Diagn</a> <a title="AJG_Vol.113.No1. page 117" href="http://viewer.zmags.com/publication/2b438029?page=117"> 94 Aziz et al. FUNCTIONAL GI DISORDERS our </a> <a title="AJG_Vol.113.No1. page 118" href="http://viewer.zmags.com/publication/2b438029?page=118"> Study Highlights WHAT IS CURRENT KNOWLEDGE ✓ Fun</a> <a title="AJG_Vol.113.No1. page 119" href="http://viewer.zmags.com/publication/2b438029?page=119"> 96 Aziz et al. FUNCTIONAL GI DISORDERS 42. </a> <a title="AJG_Vol.113.No1. page 120" href="http://viewer.zmags.com/publication/2b438029?page=120"> ORIGINAL CONTRIBUTIONS 97 see related edi</a> <a title="AJG_Vol.113.No1. page 121" href="http://viewer.zmags.com/publication/2b438029?page=121"> 98 Pauwels et al. FUNCTIONAL GI DISORDERS c</a> <a title="AJG_Vol.113.No1. page 122" href="http://viewer.zmags.com/publication/2b438029?page=122"> Manometry-impedance recording questionnaires </a> <a title="AJG_Vol.113.No1. page 123" href="http://viewer.zmags.com/publication/2b438029?page=123"> 100 Pauwels et al. FUNCTIONAL GI DISORDERS </a> <a title="AJG_Vol.113.No1. page 124" href="http://viewer.zmags.com/publication/2b438029?page=124"> 1,400 1,200 Number of flow events 1,000 800 </a> <a title="AJG_Vol.113.No1. page 125" href="http://viewer.zmags.com/publication/2b438029?page=125"> 102 Pauwels et al. 30 min baseline Pl</a> <a title="AJG_Vol.113.No1. page 126" href="http://viewer.zmags.com/publication/2b438029?page=126"> increased gastric sensitivity to mechanical diste</a> <a title="AJG_Vol.113.No1. page 127" href="http://viewer.zmags.com/publication/2b438029?page=127"> 104 Pauwels et al. FUNCTIONAL GI DISORDERS </a> <a title="AJG_Vol.113.No1. page 128" href="http://viewer.zmags.com/publication/2b438029?page=128"> ORIGINAL CONTRIBUTIONS 105 see related ed</a> <a title="AJG_Vol.113.No1. page 129" href="http://viewer.zmags.com/publication/2b438029?page=129"> 106 Schoenfeld et al. FUNCTIONAL GI DISORDER</a> <a title="AJG_Vol.113.No1. page 130" href="http://viewer.zmags.com/publication/2b438029?page=130"> cancer; active peptic ulcer disease; a history of</a> <a title="AJG_Vol.113.No1. page 131" href="http://viewer.zmags.com/publication/2b438029?page=131"> 108 Schoenfeld et al. FUNCTIONAL GI DISORDER</a> <a title="AJG_Vol.113.No1. page 132" href="http://viewer.zmags.com/publication/2b438029?page=132"> 72 μg Linaclotide in CIC 109 Patients scre</a> <a title="AJG_Vol.113.No1. page 133" href="http://viewer.zmags.com/publication/2b438029?page=133"> 110 Schoenfeld et al. 30 25 20 15 </a> <a title="AJG_Vol.113.No1. page 134" href="http://viewer.zmags.com/publication/2b438029?page=134"> 72 μg Linaclotide in CIC 111 Table 2. Effica</a> <a title="AJG_Vol.113.No1. page 135" href="http://viewer.zmags.com/publication/2b438029?page=135"> 112 Schoenfeld et al. FUNCTIONAL GI DISORDER</a> <a title="AJG_Vol.113.No1. page 136" href="http://viewer.zmags.com/publication/2b438029?page=136"> 3.0 2.5 2.0 1.5 1.0 0.5 0.0 5.0 4</a> <a title="AJG_Vol.113.No1. page 137" href="http://viewer.zmags.com/publication/2b438029?page=137"> 114 Schoenfeld et al. constipation and ab</a> <a title="AJG_Vol.113.No1. page 138" href="http://viewer.zmags.com/publication/2b438029?page=138"> ORIGINAL CONTRIBUTIONS 115 see related ed</a> <a title="AJG_Vol.113.No1. page 139" href="http://viewer.zmags.com/publication/2b438029?page=139"> 116 Mitsuhashi et al. FUNCTIONAL GI DISORDER</a> <a title="AJG_Vol.113.No1. page 140" href="http://viewer.zmags.com/publication/2b438029?page=140"> female groups. We also examined self-reported sto</a> <a title="AJG_Vol.113.No1. page 141" href="http://viewer.zmags.com/publication/2b438029?page=141"> 118 Mitsuhashi et al. During the past 12 mon</a> <a title="AJG_Vol.113.No1. page 142" href="http://viewer.zmags.com/publication/2b438029?page=142"> Normal Bowel Frequency and Consistency in the US </a> <a title="AJG_Vol.113.No1. page 143" href="http://viewer.zmags.com/publication/2b438029?page=143"> 120 Mitsuhashi et al. FUNCTIONAL GI DISORDER</a> <a title="AJG_Vol.113.No1. page 144" href="http://viewer.zmags.com/publication/2b438029?page=144"> 70 60 50 40 Percent 30 20 10 </a> <a title="AJG_Vol.113.No1. page 145" href="http://viewer.zmags.com/publication/2b438029?page=145"> 122 Mitsuhashi et al. FUNCTIONAL GI DISORDER</a> <a title="AJG_Vol.113.No1. page 146" href="http://viewer.zmags.com/publication/2b438029?page=146"> diarrhea and 67% of those who constipation fell w</a> <a title="AJG_Vol.113.No1. page 147" href="http://viewer.zmags.com/publication/2b438029?page=147"> 124 ORIGINAL CONTRIBUTIONS see related e</a> <a title="AJG_Vol.113.No1. page 148" href="http://viewer.zmags.com/publication/2b438029?page=148"> intestine, resulting in an osmotic effect increas</a> <a title="AJG_Vol.113.No1. page 149" href="http://viewer.zmags.com/publication/2b438029?page=149"> 126 Tuck et al. FUNCTIONAL GI DISORDERS Tab</a> <a title="AJG_Vol.113.No1. page 150" href="http://viewer.zmags.com/publication/2b438029?page=150"> data were assessed via paired samples t-tests. Co</a> <a title="AJG_Vol.113.No1. page 151" href="http://viewer.zmags.com/publication/2b438029?page=151"> 128 Tuck et al. Table 2. Actual dietary inta</a> <a title="AJG_Vol.113.No1. page 152" href="http://viewer.zmags.com/publication/2b438029?page=152"> P = 0.000 </a> <a title="AJG_Vol.113.No1. page 153" href="http://viewer.zmags.com/publication/2b438029?page=153"> Placebo Half-dose Full-dose Low FODMA</a> <a title="AJG_Vol.113.No1. page 154" href="http://viewer.zmags.com/publication/2b438029?page=154"> 20,000 15,000 10,000 Hydrogen (p.p.m.12 h) </a> <a title="AJG_Vol.113.No1. page 155" href="http://viewer.zmags.com/publication/2b438029?page=155"> 132 Tuck et al. a 100 80 60 40 </a> <a title="AJG_Vol.113.No1. page 156" href="http://viewer.zmags.com/publication/2b438029?page=156"> by the dietary restrictions and keeping of food r</a> <a title="AJG_Vol.113.No1. page 157" href="http://viewer.zmags.com/publication/2b438029?page=157"> 134 Tuck et al. FUNCTIONAL GI DISORDERS </a> <a title="AJG_Vol.113.No1. page 158" href="http://viewer.zmags.com/publication/2b438029?page=158"> ORIGINAL CONTRIBUTIONS 135 sCeMeErelated e</a> <a title="AJG_Vol.113.No1. page 159" href="http://viewer.zmags.com/publication/2b438029?page=159"> 136 Badihian et al. PEDIATRICS system dysfu</a> <a title="AJG_Vol.113.No1. page 160" href="http://viewer.zmags.com/publication/2b438029?page=160"> Prophylaxis of Cyclic Vomiting Syndrome 137 </a> <a title="AJG_Vol.113.No1. page 161" href="http://viewer.zmags.com/publication/2b438029?page=161"> 138 Badihian et al. PEDIATRICS Table 1. Bas</a> <a title="AJG_Vol.113.No1. page 162" href="http://viewer.zmags.com/publication/2b438029?page=162"> Prophylaxis of Cyclic Vomiting Syndrome 139 </a> <a title="AJG_Vol.113.No1. page 163" href="http://viewer.zmags.com/publication/2b438029?page=163"> 140 Badihian et al. PEDIATRICS revised the </a> <a title="AJG_Vol.113.No1. page 164" href="http://viewer.zmags.com/publication/2b438029?page=164"> CONTINUING MEDICAL EDUCATION 141 CME Con</a> <a title="AJG_Vol.113.No1. page 165" href="http://viewer.zmags.com/publication/2b438029?page=165"> 142 LETTERS TO THE EDITOR Time to Make </a> <a title="AJG_Vol.113.No1. page 166" href="http://viewer.zmags.com/publication/2b438029?page=166"> CONFLICT OF INTEREST The authors declare no confl</a> <a title="AJG_Vol.113.No1. page 167" href="http://viewer.zmags.com/publication/2b438029?page=167"> 144 Letters to the Editor Alternative Time</a> <a title="AJG_Vol.113.No1. page 168" href="http://viewer.zmags.com/publication/2b438029?page=168"> in functional dyspepsia (FD) defined by Rome IV c</a> <a title="AJG_Vol.113.No1. page 169" href="http://viewer.zmags.com/publication/2b438029?page=169"> 146 Letters to the Editor Fig</a> <a title="AJG_Vol.113.No1. page 170" href="http://viewer.zmags.com/publication/2b438029?page=170"> Letters to the Editor 147 ab </a> <a title="AJG_Vol.113.No1. page 171" href="http://viewer.zmags.com/publication/2b438029?page=171"> 148 Letters to the Editor migrational beha</a> <a title="AJG_Vol.113.No1. page 172" href="http://viewer.zmags.com/publication/2b438029?page=172"> and terminal ileum resection. Pathologic analysis</a> <a title="AJG_Vol.113.No1. page 173" href="http://viewer.zmags.com/publication/2b438029?page=173"> 150 Letters to the Editor </a> <a title="AJG_Vol.113.No1. page 174" href="http://viewer.zmags.com/publication/2b438029?page=174"> Letters to the Editor 151 </a> <a title="AJG_Vol.113.No1. page 175" href="http://viewer.zmags.com/publication/2b438029?page=175"> 152 Letters to the Editor ab JE cd Cont</a> <a title="AJG_Vol.113.No1. page 176" href="http://viewer.zmags.com/publication/2b438029?page=176"> ANNOUNCEMENTS 153 CALENDAR OF COURSES, S</a> <a title="AJG_Vol.113.No1. page 177" href="http://viewer.zmags.com/publication/2b438029?page=177"> 154 ERRATA, CORRIGENDA AND RETRACTIONS ERRATU</a> <a title="AJG_Vol.113.No1. page 178" href="http://viewer.zmags.com/publication/2b438029?page=178"> Errata, Corrigenda and Retractions 155 Cor</a> <a title="AJG_Vol.113.No1. page 179" href="http://viewer.zmags.com/publication/2b438029?page=179"> CLASSIFIEDS Physician-Led Medicine in Montana Ga</a> <a title="AJG_Vol.113.No1. page 180" href="http://viewer.zmags.com/publication/2b438029?page=180"> IMPORTANT SAFETY INFORMATION SUPREP® Bowel Prep K</a> <a title="AJG_Vol.113.No1. page 181" href="http://viewer.zmags.com/publication/2b438029?page=181"> #1 MOST PRESCRIBED, BRANDED BOWEL PREP KIT1 A</a>