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<br /> In ThIs Issue:<br /> VOLUME LXXiV, NUMBER 4, WiNtER 2012<br /> Minding Brains • Mending Retinas • Pumping Blood<br /> 2 www.caltech.edu<br /> Stay connected to campus, wherever you are.<br /> 3 From the President<br /> 4 Random Walk<br /> Scintillating Neutrinos • Sporulating Membranes • Selenocentric Spacecraft<br /> • And More!<br /> 14 Different Minds<br /> by Lori oLiwenstein<br /> the word autism covers what is really a spectrum of disorders, but they all<br /> appear to result from nonstandard connections between various parts of<br /> the brain.<br /> 20 Connecting the Dots<br /> by Katie neith<br /> implantable electronics can reconnect parts of the nervous system that<br /> have been damaged by disease or disability.<br /> 26 Programming Molecular Apps<br /> by Marcus y. woo<br /> the future of programming may lie with DNA—but the vision behind<br /> tomorro<a title="E&amp;S Winter 2012 page 1" href="http://viewer.zmags.com/publication/2e0fb2ad?page=1"> In ThIs Issue: VOLUME LXXiV, NUMBER 4, WiNtE</a> <a title="E&amp;S Winter 2012 page 2" href="http://viewer.zmags.com/publication/2e0fb2ad?page=2"> 2 www.caltech.edu Stay connected to ca</a> <a title="E&amp;S Winter 2012 page 3" href="http://viewer.zmags.com/publication/2e0fb2ad?page=3"> VOLUME LXXiV, NUMBER 4, WiNtER 2012</a> <a title="E&amp;S Winter 2012 page 4" href="http://viewer.zmags.com/publication/2e0fb2ad?page=4"> www.caltech.edu Stay connected no matter where yo</a> <a title="E&amp;S Winter 2012 page 5" href="http://viewer.zmags.com/publication/2e0fb2ad?page=5"> You might not think of Caltech when you think</a> <a title="E&amp;S Winter 2012 page 6" href="http://viewer.zmags.com/publication/2e0fb2ad?page=6"> Random This image is a glimpse into the depths </a> <a title="E&amp;S Winter 2012 page 7" href="http://viewer.zmags.com/publication/2e0fb2ad?page=7"> Walk thingS that caught our eye . . . </a> <a title="E&amp;S Winter 2012 page 8" href="http://viewer.zmags.com/publication/2e0fb2ad?page=8"> random walk </a> <a title="E&amp;S Winter 2012 page 9" href="http://viewer.zmags.com/publication/2e0fb2ad?page=9"> Flip it and ReveRse it A team of Caltech res</a> <a title="E&amp;S Winter 2012 page 10" href="http://viewer.zmags.com/publication/2e0fb2ad?page=10"> MoonwaRd Bound GRAiL, NASA’s Gravity Recovery and</a> <a title="E&amp;S Winter 2012 page 11" href="http://viewer.zmags.com/publication/2e0fb2ad?page=11"> winter 2012 ENGINEERING & SCIENCE 9</a> <a title="E&amp;S Winter 2012 page 12" href="http://viewer.zmags.com/publication/2e0fb2ad?page=12"> 10 ENGINEERING & SCIENCE winter 2012</a> <a title="E&amp;S Winter 2012 page 13" href="http://viewer.zmags.com/publication/2e0fb2ad?page=13"> Jackie BaRton wins national Medal oF science Chem</a> <a title="E&amp;S Winter 2012 page 14" href="http://viewer.zmags.com/publication/2e0fb2ad?page=14"> the aRt oF science Caltech’s third annual Art of </a> <a title="E&amp;S Winter 2012 page 15" href="http://viewer.zmags.com/publication/2e0fb2ad?page=15"> FiRsT-PRiZE winnER (left) aRTisT: Floris Van Breu</a> <a title="E&amp;S Winter 2012 page 16" href="http://viewer.zmags.com/publication/2e0fb2ad?page=16"> Different if there’s one thing Ralph Adolphs want</a> <a title="E&amp;S Winter 2012 page 17" href="http://viewer.zmags.com/publication/2e0fb2ad?page=17"> MinDs By Lori Oliwenstein </a> <a title="E&amp;S Winter 2012 page 18" href="http://viewer.zmags.com/publication/2e0fb2ad?page=18"> Patterson observed the same neuro- pathology </a> <a title="E&amp;S Winter 2012 page 19" href="http://viewer.zmags.com/publication/2e0fb2ad?page=19"> thing from eye-tracking, to reasoning, to complex</a> <a title="E&amp;S Winter 2012 page 20" href="http://viewer.zmags.com/publication/2e0fb2ad?page=20"> </a> <a title="E&amp;S Winter 2012 page 21" href="http://viewer.zmags.com/publication/2e0fb2ad?page=21"> nizes itself functionally during develop- ment, s</a> <a title="E&amp;S Winter 2012 page 22" href="http://viewer.zmags.com/publication/2e0fb2ad?page=22"> A multidisciplinary approach to building implanta</a> <a title="E&amp;S Winter 2012 page 23" href="http://viewer.zmags.com/publication/2e0fb2ad?page=23"> Like the fiber-optic network beneath a teeming me</a> <a title="E&amp;S Winter 2012 page 24" href="http://viewer.zmags.com/publication/2e0fb2ad?page=24"> back of the brain. Despite the lengthy explanatio</a> <a title="E&amp;S Winter 2012 page 25" href="http://viewer.zmags.com/publication/2e0fb2ad?page=25"> from the lab’s research. With such an implant, a </a> <a title="E&amp;S Winter 2012 page 26" href="http://viewer.zmags.com/publication/2e0fb2ad?page=26"> keeping an electrical eye on the future Just ups</a> <a title="E&amp;S Winter 2012 page 27" href="http://viewer.zmags.com/publication/2e0fb2ad?page=27"> roBotS in diSguiSe Joel Burdick likes to call hi</a> <a title="E&amp;S Winter 2012 page 28" href="http://viewer.zmags.com/publication/2e0fb2ad?page=28"> </a> <a title="E&amp;S Winter 2012 page 29" href="http://viewer.zmags.com/publication/2e0fb2ad?page=29"> PROGRAMMING MOLECULAR APPS By Marcus Y. Woo </a> <a title="E&amp;S Winter 2012 page 30" href="http://viewer.zmags.com/publication/2e0fb2ad?page=30"> To the left: This map of north and south america,</a> <a title="E&amp;S Winter 2012 page 31" href="http://viewer.zmags.com/publication/2e0fb2ad?page=31"> woo and Rothemund, nature chemistry, vol. 3, pp. </a> <a title="E&amp;S Winter 2012 page 32" href="http://viewer.zmags.com/publication/2e0fb2ad?page=32"> c* b* b </a> <a title="E&amp;S Winter 2012 page 33" href="http://viewer.zmags.com/publication/2e0fb2ad?page=33"> a single strand of Rna can fold onto itself to fo</a> <a title="E&amp;S Winter 2012 page 34" href="http://viewer.zmags.com/publication/2e0fb2ad?page=34"> To the right: a “smart drug” might one day consis</a> <a title="E&amp;S Winter 2012 page 35" href="http://viewer.zmags.com/publication/2e0fb2ad?page=35"> Process of Elimination, by ann Erpino (http://www</a> <a title="E&amp;S Winter 2012 page 36" href="http://viewer.zmags.com/publication/2e0fb2ad?page=36"> Naturally Inspired By Kimm Fesenmaier </a> <a title="E&amp;S Winter 2012 page 37" href="http://viewer.zmags.com/publication/2e0fb2ad?page=37"> an unlikely muse: The embryonic zebrafish heart i</a> <a title="E&amp;S Winter 2012 page 38" href="http://viewer.zmags.com/publication/2e0fb2ad?page=38"> Right: in these frames from a video, water drople</a> <a title="E&amp;S Winter 2012 page 39" href="http://viewer.zmags.com/publication/2e0fb2ad?page=39"> Super-hydro-phoBic- lotuS-acting- nano-tuBuleS Z</a> <a title="E&amp;S Winter 2012 page 40" href="http://viewer.zmags.com/publication/2e0fb2ad?page=40"> By Kathy Svitil </a> <a title="E&amp;S Winter 2012 page 41" href="http://viewer.zmags.com/publication/2e0fb2ad?page=41"> At any given moment, more than 100,000 people in </a> <a title="E&amp;S Winter 2012 page 42" href="http://viewer.zmags.com/publication/2e0fb2ad?page=42"> JULiA KORNFiELD Ophir, who </a> <a title="E&amp;S Winter 2012 page 43" href="http://viewer.zmags.com/publication/2e0fb2ad?page=43"> the eye.) “We want to understand how we can guide</a> <a title="E&amp;S Winter 2012 page 44" href="http://viewer.zmags.com/publication/2e0fb2ad?page=44"> 2010 hEaTh</a> <a title="E&amp;S Winter 2012 page 45" href="http://viewer.zmags.com/publication/2e0fb2ad?page=45"> anSlational mediCine ave made an impact in transl</a> <a title="E&amp;S Winter 2012 page 46" href="http://viewer.zmags.com/publication/2e0fb2ad?page=46"> We asked CalteCh alums to tell us their favorite </a> <a title="E&amp;S Winter 2012 page 47" href="http://viewer.zmags.com/publication/2e0fb2ad?page=47"> </a> <a title="E&amp;S Winter 2012 page 48" href="http://viewer.zmags.com/publication/2e0fb2ad?page=48"> California institute of technology Pasadena, Cali</a>