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<br /> ARCHIVE<br /> 2<br /> VOLUME 112 NUMBER 1 JANUARY 2017<br /> www.nature.com/ajg<br /> official publication of the american college of gastroenterology<br /> LEADING ARTICLES OF THE MONTH<br /> Practice Guidelines<br /> 18 ACG Clinical Guideline: Evaluation of Abnormal Liver Chemistries CME<br /> Paul Y. Kwo, Stanley M. Cohen and Joseph K. Lim<br /> 37 Recommendations on Fecal Immunochemical Testing to Screen for<br /> Colorectal Neoplasia: A Consensus Statement by the US<br /> Multi-Society Task Force on Colorectal Cancer<br /> Douglas J. Robertson, Jeffrey K. Lee, C. Richard Boland, Jason A. Dominitz,<br /> Francis M. Giardiello, David A. Johnson, Tonya Kaltenbach,<br /> David Lieberman, Theodore R. Levin and Douglas K. Rex<br /> Clinical and Systematic Reviews<br /> 65 Screening for Celiac Disease in Irritable Bowel Syndrome:<br /> An Upd<a title="AJG_Vol.112.No7 page 1" href="http://viewer.zmags.com/publication/31160122?page=1"> ARCHIVE 2 VOLUME 112 NUMBER 1 JANUARY 2017 www</a> <a title="AJG_Vol.112.No7 page 2" href="http://viewer.zmags.com/publication/31160122?page=2"> VOLUME 112 NUMBER 7 JULY 2017 www.nature.com/ajg </a> <a title="AJG_Vol.112.No7 page 3" href="http://viewer.zmags.com/publication/31160122?page=3"> New for GI Endoscopic Resections Visit eleviewUS.</a> <a title="AJG_Vol.112.No7 page 4" href="http://viewer.zmags.com/publication/31160122?page=4"> * Test to uncover man</a> <a title="AJG_Vol.112.No7 page 5" href="http://viewer.zmags.com/publication/31160122?page=5"> www.nature.com/ajg The American Journal o</a> <a title="AJG_Vol.112.No7 page 6" href="http://viewer.zmags.com/publication/31160122?page=6"> For first-line constipation therapy, stick with t</a> <a title="AJG_Vol.112.No7 page 7" href="http://viewer.zmags.com/publication/31160122?page=7"> official publication of the american college</a> <a title="AJG_Vol.112.No7 page 8" href="http://viewer.zmags.com/publication/31160122?page=8"> WHAT ARE BIOSIMILARS? Let’s Clarify Biosimilar</a> <a title="AJG_Vol.112.No7 page 9" href="http://viewer.zmags.com/publication/31160122?page=9"> IMPORTANT SAFETY INFORMATION WARNING: RISK OF SE</a> <a title="AJG_Vol.112.No7 page 10" href="http://viewer.zmags.com/publication/31160122?page=10"> FOR ADULTS WITH CHRONIC IDIOPATHIC CONSTIPATION (</a> <a title="AJG_Vol.112.No7 page 11" href="http://viewer.zmags.com/publication/31160122?page=11"> Trulance™ (plecanatide) tablets, for oral use Rx </a> <a title="AJG_Vol.112.No7 page 12" href="http://viewer.zmags.com/publication/31160122?page=12"> GI QUALITY IMPROVEMENT CONSORTIUM, LTD. P Settin</a> <a title="AJG_Vol.112.No7 page 13" href="http://viewer.zmags.com/publication/31160122?page=13"> Attend an ACG Regional Postgraduate Course close </a> <a title="AJG_Vol.112.No7 page 14" href="http://viewer.zmags.com/publication/31160122?page=14"> An 84-year-old woman presented with jugular venou</a> <a title="AJG_Vol.112.No7 page 15" href="http://viewer.zmags.com/publication/31160122?page=15"> CONTENTS </a> <a title="AJG_Vol.112.No7 page 16" href="http://viewer.zmags.com/publication/31160122?page=16"> 2.0 1.0 www.nature.com/ajg P<0.0001 Serum</a> <a title="AJG_Vol.112.No7 page 17" href="http://viewer.zmags.com/publication/31160122?page=17"> ADVERTISEMENT Persistent diarrhea: are there fast</a> <a title="AJG_Vol.112.No7 page 18" href="http://viewer.zmags.com/publication/31160122?page=18"> THE RED SECTION 977 see related editorial</a> <a title="AJG_Vol.112.No7 page 19" href="http://viewer.zmags.com/publication/31160122?page=19"> 978 THE RED SECTION HOW I APPROACH IT Table </a> <a title="AJG_Vol.112.No7 page 20" href="http://viewer.zmags.com/publication/31160122?page=20"> THE RED SECTION 979 No </a> <a title="AJG_Vol.112.No7 page 21" href="http://viewer.zmags.com/publication/31160122?page=21"> 980 THE RED SECTION HOW I APPROACH IT REFERE</a> <a title="AJG_Vol.112.No7 page 22" href="http://viewer.zmags.com/publication/31160122?page=22"> THE RED SECTION 981 see related editorial</a> <a title="AJG_Vol.112.No7 page 23" href="http://viewer.zmags.com/publication/31160122?page=23"> 982 THE RED SECTION IN MY OWN VOICE HELPING </a> <a title="AJG_Vol.112.No7 page 24" href="http://viewer.zmags.com/publication/31160122?page=24"> Springer Nature </a> <a title="AJG_Vol.112.No7 page 25" href="http://viewer.zmags.com/publication/31160122?page=25"> 984 THE RED SECTION Inferior Cava Vein Syn</a> <a title="AJG_Vol.112.No7 page 26" href="http://viewer.zmags.com/publication/31160122?page=26"> THE RED SECTION 985 Video of the Month Dive</a> <a title="AJG_Vol.112.No7 page 27" href="http://viewer.zmags.com/publication/31160122?page=27"> 986 THE RED SECTION Video of the Month Use</a> <a title="AJG_Vol.112.No7 page 28" href="http://viewer.zmags.com/publication/31160122?page=28"> CLINICAL GUIDELINES 987 CME Continuing M</a> <a title="AJG_Vol.112.No7 page 29" href="http://viewer.zmags.com/publication/31160122?page=29"> 988 CLINICAL GUIDELINES CME ACG and CAG </a> <a title="AJG_Vol.112.No7 page 30" href="http://viewer.zmags.com/publication/31160122?page=30"> lasting at least 1 month. This can be associated </a> <a title="AJG_Vol.112.No7 page 31" href="http://viewer.zmags.com/publication/31160122?page=31"> 990 Moayyedi et al. Table 2. PICO statemen</a> <a title="AJG_Vol.112.No7 page 32" href="http://viewer.zmags.com/publication/31160122?page=32"> The quality of evidence was expressed as high (es</a> <a title="AJG_Vol.112.No7 page 33" href="http://viewer.zmags.com/publication/31160122?page=33"> 992 Moayyedi et al. over the age of 60 pr</a> <a title="AJG_Vol.112.No7 page 34" href="http://viewer.zmags.com/publication/31160122?page=34"> ACG and CAG Clinical Guideline: Management of Dys</a> <a title="AJG_Vol.112.No7 page 35" href="http://viewer.zmags.com/publication/31160122?page=35"> 994 Moayyedi et al. Table 4. Summary of findi</a> <a title="AJG_Vol.112.No7 page 36" href="http://viewer.zmags.com/publication/31160122?page=36"> ACG and CAG Clinical Guideline: Management of Dys</a> <a title="AJG_Vol.112.No7 page 37" href="http://viewer.zmags.com/publication/31160122?page=37"> 996 Moayyedi et al. </a> <a title="AJG_Vol.112.No7 page 38" href="http://viewer.zmags.com/publication/31160122?page=38"> STATEMENT 6. WE SUGGEST DYSPEPSIA PATIENTS UNDER </a> <a title="AJG_Vol.112.No7 page 39" href="http://viewer.zmags.com/publication/31160122?page=39"> 998 Moayyedi et al. of the evidence was m</a> <a title="AJG_Vol.112.No7 page 40" href="http://viewer.zmags.com/publication/31160122?page=40"> The quality of the data is very low despite a</a> <a title="AJG_Vol.112.No7 page 41" href="http://viewer.zmags.com/publication/31160122?page=41"> 1000 Moayyedi et al. ACKNOWLEDGMENTS </a> <a title="AJG_Vol.112.No7 page 42" href="http://viewer.zmags.com/publication/31160122?page=42"> 41. Arents NLA, Thijs JC, van Zwet AA et al. App</a> <a title="AJG_Vol.112.No7 page 43" href="http://viewer.zmags.com/publication/31160122?page=43"> 1002 Moayyedi et al. 87. Mazzoleni LE, Sa</a> <a title="AJG_Vol.112.No7 page 44" href="http://viewer.zmags.com/publication/31160122?page=44"> 136. de Groot GH, de Both PS. Cisapride in functi</a> <a title="AJG_Vol.112.No7 page 45" href="http://viewer.zmags.com/publication/31160122?page=45"> 1004 Moayyedi et al. APPENDIX 1 SEARCH STRAT</a> <a title="AJG_Vol.112.No7 page 46" href="http://viewer.zmags.com/publication/31160122?page=46"> ACG and CAG Clinical Guideline: Management of Dys</a> <a title="AJG_Vol.112.No7 page 47" href="http://viewer.zmags.com/publication/31160122?page=47"> 1006 Moayyedi et al. Topic Medline (Databa</a> <a title="AJG_Vol.112.No7 page 48" href="http://viewer.zmags.com/publication/31160122?page=48"> ACG and CAG Clinical Guideline: Management of Dys</a> <a title="AJG_Vol.112.No7 page 49" href="http://viewer.zmags.com/publication/31160122?page=49"> 1008 Moayyedi et al. APPENDIX 2 Forest plo</a> <a title="AJG_Vol.112.No7 page 50" href="http://viewer.zmags.com/publication/31160122?page=50"> ACG and CAG Clinical Guideline: Management of Dys</a> <a title="AJG_Vol.112.No7 page 51" href="http://viewer.zmags.com/publication/31160122?page=51"> 1010 Moayyedi et al. Figure 9. Fores</a> <a title="AJG_Vol.112.No7 page 52" href="http://viewer.zmags.com/publication/31160122?page=52"> ACG and CAG Clinical Guideline: Management of Dys</a> <a title="AJG_Vol.112.No7 page 53" href="http://viewer.zmags.com/publication/31160122?page=53"> 1012 Moayyedi et al. Figure 13. Forest </a> <a title="AJG_Vol.112.No7 page 54" href="http://viewer.zmags.com/publication/31160122?page=54"> ACG and CAG Clinical Guideline: Management of Dys</a> <a title="AJG_Vol.112.No7 page 55" href="http://viewer.zmags.com/publication/31160122?page=55"> 1014 CLINICAL GUIDELINES CME Continuing</a> <a title="AJG_Vol.112.No7 page 56" href="http://viewer.zmags.com/publication/31160122?page=56"> CLINICAL GUIDELINES 1015 CME Continuing </a> <a title="AJG_Vol.112.No7 page 57" href="http://viewer.zmags.com/publication/31160122?page=57"> 1016 CLINICAL GUIDELINES CME Colorectal</a> <a title="AJG_Vol.112.No7 page 58" href="http://viewer.zmags.com/publication/31160122?page=58"> ing recommendations of the MSTF for screening in </a> <a title="AJG_Vol.112.No7 page 59" href="http://viewer.zmags.com/publication/31160122?page=59"> 1018 Rex et al. Table 1. Approaches to off</a> <a title="AJG_Vol.112.No7 page 60" href="http://viewer.zmags.com/publication/31160122?page=60"> particular strengths or weaknesses detecting 1 or</a> <a title="AJG_Vol.112.No7 page 61" href="http://viewer.zmags.com/publication/31160122?page=61"> 1020 Rex et al. usually small lesions and</a> <a title="AJG_Vol.112.No7 page 62" href="http://viewer.zmags.com/publication/31160122?page=62"> Table 3. Tools for patients to enhance colonoscop</a> <a title="AJG_Vol.112.No7 page 63" href="http://viewer.zmags.com/publication/31160122?page=63"> 1022 Rex et al. despite an extensive lite</a> <a title="AJG_Vol.112.No7 page 64" href="http://viewer.zmags.com/publication/31160122?page=64"> screening (114). Screening remains cost-effective</a> <a title="AJG_Vol.112.No7 page 65" href="http://viewer.zmags.com/publication/31160122?page=65"> 1024 Rex et al. those who decline colonos</a> <a title="AJG_Vol.112.No7 page 66" href="http://viewer.zmags.com/publication/31160122?page=66"> 1025 Table 5. MSTF recommendations for persons</a> <a title="AJG_Vol.112.No7 page 67" href="http://viewer.zmags.com/publication/31160122?page=67"> 1026 Rex et al. The best course of act</a> <a title="AJG_Vol.112.No7 page 68" href="http://viewer.zmags.com/publication/31160122?page=68"> higher pretest probability of neoplasia, and FIT </a> <a title="AJG_Vol.112.No7 page 69" href="http://viewer.zmags.com/publication/31160122?page=69"> 1028 Rex et al. 34. Giardiello FM, Allen </a> <a title="AJG_Vol.112.No7 page 70" href="http://viewer.zmags.com/publication/31160122?page=70"> 83. Hassan C, Rex DK, Zullo A et al. Loss of eff</a> <a title="AJG_Vol.112.No7 page 71" href="http://viewer.zmags.com/publication/31160122?page=71"> 1030 Rex et al. 134. Rex DK, Mark D, Clark</a> <a title="AJG_Vol.112.No7 page 72" href="http://viewer.zmags.com/publication/31160122?page=72"> CLINICAL GUIDELINES 1031 CME Continuing </a> <a title="AJG_Vol.112.No7 page 73" href="http://viewer.zmags.com/publication/31160122?page=73"> 1032 QUALITY INDICATORS FOR GI ENDOSCOPIC PROC</a> <a title="AJG_Vol.112.No7 page 74" href="http://viewer.zmags.com/publication/31160122?page=74"> Society for Gastrointestinal Endoscopy (ASGE)/Ame</a> <a title="AJG_Vol.112.No7 page 75" href="http://viewer.zmags.com/publication/31160122?page=75"> 1034 Wani et al. Recruitment of Internati</a> <a title="AJG_Vol.112.No7 page 76" href="http://viewer.zmags.com/publication/31160122?page=76"> the IPRAS is based on the nonparametric measure o</a> <a title="AJG_Vol.112.No7 page 77" href="http://viewer.zmags.com/publication/31160122?page=77"> 1036 Wani et al. Table 1. Appropriate qual</a> <a title="AJG_Vol.112.No7 page 78" href="http://viewer.zmags.com/publication/31160122?page=78"> 1037 Table 2. Appropriate quality indicators w</a> <a title="AJG_Vol.112.No7 page 79" href="http://viewer.zmags.com/publication/31160122?page=79"> 1038 Wani et al. The rate at which landma</a> <a title="AJG_Vol.112.No7 page 80" href="http://viewer.zmags.com/publication/31160122?page=80"> in the management of BE-related neoplasia in pati</a> <a title="AJG_Vol.112.No7 page 81" href="http://viewer.zmags.com/publication/31160122?page=81"> 1040 Wani et al. Table 3. Quality indicators</a> <a title="AJG_Vol.112.No7 page 82" href="http://viewer.zmags.com/publication/31160122?page=82"> During endoscopic surveillance after EET, the rat</a> <a title="AJG_Vol.112.No7 page 83" href="http://viewer.zmags.com/publication/31160122?page=83"> 1042 Wani et al. Table 4. After-study ques</a> <a title="AJG_Vol.112.No7 page 84" href="http://viewer.zmags.com/publication/31160122?page=84"> of the numerator and denominator along with the p</a> <a title="AJG_Vol.112.No7 page 85" href="http://viewer.zmags.com/publication/31160122?page=85"> 1044 Wani et al. Ironwood Pharmaceuticals</a> <a title="AJG_Vol.112.No7 page 86" href="http://viewer.zmags.com/publication/31160122?page=86"> 46. Sangle NA, Taylor SL, Emond MJ et al. Overdi</a> <a title="AJG_Vol.112.No7 page 87" href="http://viewer.zmags.com/publication/31160122?page=87"> 1046 Wani et al. 92. Fleischer DE, Overho</a> <a title="AJG_Vol.112.No7 page 88" href="http://viewer.zmags.com/publication/31160122?page=88"> 1047 APPENDIX 2 Ranking instructions provided</a> <a title="AJG_Vol.112.No7 page 89" href="http://viewer.zmags.com/publication/31160122?page=89"> 1048 Wani et al. # Searches </a> <a title="AJG_Vol.112.No7 page 90" href="http://viewer.zmags.com/publication/31160122?page=90"> ORIGINAL CONTRIBUTIONS 1049 see related ed</a> <a title="AJG_Vol.112.No7 page 91" href="http://viewer.zmags.com/publication/31160122?page=91"> 1050 Nguyen et al. ESOPHAGUS neoplastic cha</a> <a title="AJG_Vol.112.No7 page 92" href="http://viewer.zmags.com/publication/31160122?page=92"> cases with known nondysplastic BE at BE diagnosis</a> <a title="AJG_Vol.112.No7 page 93" href="http://viewer.zmags.com/publication/31160122?page=93"> 1052 Nguyen et al. ESOPHAGUS Table 1. Numbe</a> <a title="AJG_Vol.112.No7 page 94" href="http://viewer.zmags.com/publication/31160122?page=94"> EAC Risk Does Not Decrease in Persistent Non-Neop</a> <a title="AJG_Vol.112.No7 page 95" href="http://viewer.zmags.com/publication/31160122?page=95"> 1054 Nguyen et al. ESOPHAGUS in later years</a> <a title="AJG_Vol.112.No7 page 96" href="http://viewer.zmags.com/publication/31160122?page=96"> DISCLAIMER The opinions expressed reflect those o</a> <a title="AJG_Vol.112.No7 page 97" href="http://viewer.zmags.com/publication/31160122?page=97"> 1056 EDITORIAL see related article on pa</a> <a title="AJG_Vol.112.No7 page 98" href="http://viewer.zmags.com/publication/31160122?page=98"> LIMITATIONS OF CURRENT SURVEILLANCE STRATEGY As c</a> <a title="AJG_Vol.112.No7 page 99" href="http://viewer.zmags.com/publication/31160122?page=99"> 1058 Wani and Gaddam Table 1. Author Stud</a> <a title="AJG_Vol.112.No7 page 100" href="http://viewer.zmags.com/publication/31160122?page=100"> Editorial 1059 PHYSICIAN FACTORS (TECHNICA</a> <a title="AJG_Vol.112.No7 page 101" href="http://viewer.zmags.com/publication/31160122?page=101"> 1060 Wani and Gaddam ESOPHAGUS REFERENCES 1</a> <a title="AJG_Vol.112.No7 page 102" href="http://viewer.zmags.com/publication/31160122?page=102"> ORIGINAL CONTRIBUTIONS 1061 see related e</a> <a title="AJG_Vol.112.No7 page 103" href="http://viewer.zmags.com/publication/31160122?page=103"> 1062 Warners et al. ESOPHAGUS disease (4,5)</a> <a title="AJG_Vol.112.No7 page 104" href="http://viewer.zmags.com/publication/31160122?page=104"> eosinophil count per HPF (an area of 0.24 mm2). A</a> <a title="AJG_Vol.112.No7 page 105" href="http://viewer.zmags.com/publication/31160122?page=105"> 1064 Warners et al. ESOPHAGUS pared using t</a> <a title="AJG_Vol.112.No7 page 106" href="http://viewer.zmags.com/publication/31160122?page=106"> controls was completely impermeable for fluoresce</a> <a title="AJG_Vol.112.No7 page 107" href="http://viewer.zmags.com/publication/31160122?page=107"> m) </a> <a title="AJG_Vol.112.No7 page 108" href="http://viewer.zmags.com/publication/31160122?page=108"> a 3,000 m) 2,000 Mucosal impedance (Ω 1,000 </a> <a title="AJG_Vol.112.No7 page 109" href="http://viewer.zmags.com/publication/31160122?page=109"> b P < 0.001 </a> <a title="AJG_Vol.112.No7 page 110" href="http://viewer.zmags.com/publication/31160122?page=110"> a 0.1 0.01 Relative FLG expression 0.001 </a> <a title="AJG_Vol.112.No7 page 111" href="http://viewer.zmags.com/publication/31160122?page=111"> 1070 Warners et al. ESOPHAGUS shown that su</a> <a title="AJG_Vol.112.No7 page 112" href="http://viewer.zmags.com/publication/31160122?page=112"> Study Highlights WHAT IS CURRENT KNOWLEDGE ✓ Eos</a> <a title="AJG_Vol.112.No7 page 113" href="http://viewer.zmags.com/publication/31160122?page=113"> 1072 EDITORIAL see related article on pa</a> <a title="AJG_Vol.112.No7 page 114" href="http://viewer.zmags.com/publication/31160122?page=114"> ful diet therapy when compared to controls. These</a> <a title="AJG_Vol.112.No7 page 115" href="http://viewer.zmags.com/publication/31160122?page=115"> 1074 ORIGINAL CONTRIBUTIONS see related </a> <a title="AJG_Vol.112.No7 page 116" href="http://viewer.zmags.com/publication/31160122?page=116"> some quantitative measurements such as pharyngeal</a> <a title="AJG_Vol.112.No7 page 117" href="http://viewer.zmags.com/publication/31160122?page=117"> 1076 Park et al. From December 2012 to M</a> <a title="AJG_Vol.112.No7 page 118" href="http://viewer.zmags.com/publication/31160122?page=118"> Feeding Method and Aspiration Pneumonia Using HRM</a> <a title="AJG_Vol.112.No7 page 119" href="http://viewer.zmags.com/publication/31160122?page=119"> 1078 Park et al. a </a> <a title="AJG_Vol.112.No7 page 120" href="http://viewer.zmags.com/publication/31160122?page=120"> Feeding Method and Aspiration Pneumonia Using HRM</a> <a title="AJG_Vol.112.No7 page 121" href="http://viewer.zmags.com/publication/31160122?page=121"> 1080 Park et al. a 1.0 0.8 0.6 </a> <a title="AJG_Vol.112.No7 page 122" href="http://viewer.zmags.com/publication/31160122?page=122"> a 1.0 0.8 0.6 0.4 Cumulative incidence</a> <a title="AJG_Vol.112.No7 page 123" href="http://viewer.zmags.com/publication/31160122?page=123"> 1082 Park et al. ESOPHAGUS ever, the findin</a> <a title="AJG_Vol.112.No7 page 124" href="http://viewer.zmags.com/publication/31160122?page=124"> Specific author contributions: Manuscript draftin</a> <a title="AJG_Vol.112.No7 page 125" href="http://viewer.zmags.com/publication/31160122?page=125"> 1084 ORIGINAL CONTRIBUTIONS see related e</a> <a title="AJG_Vol.112.No7 page 126" href="http://viewer.zmags.com/publication/31160122?page=126"> INTRODUCTION Proton-pump inhibitors (PPIs) effect</a> <a title="AJG_Vol.112.No7 page 127" href="http://viewer.zmags.com/publication/31160122?page=127"> 1086 Wang et al. patient (31 December 201</a> <a title="AJG_Vol.112.No7 page 128" href="http://viewer.zmags.com/publication/31160122?page=128"> PPIs And Risk of First-Time Ischemic Stroke 10</a> <a title="AJG_Vol.112.No7 page 129" href="http://viewer.zmags.com/publication/31160122?page=129"> 1088 Wang et al. STOMACH Table 1. Continued</a> <a title="AJG_Vol.112.No7 page 130" href="http://viewer.zmags.com/publication/31160122?page=130"> PPIs And Risk of First-Time Ischemic Stroke 10</a> <a title="AJG_Vol.112.No7 page 131" href="http://viewer.zmags.com/publication/31160122?page=131"> 1090 Wang et al. STOMACH Table 3. Demograph</a> <a title="AJG_Vol.112.No7 page 132" href="http://viewer.zmags.com/publication/31160122?page=132"> PPIs And Risk of First-Time Ischemic Stroke 10</a> <a title="AJG_Vol.112.No7 page 133" href="http://viewer.zmags.com/publication/31160122?page=133"> 1092 Wang et al. STOMACH the manuscript: Ye</a> <a title="AJG_Vol.112.No7 page 134" href="http://viewer.zmags.com/publication/31160122?page=134"> 28. Cheng CL, Kao YH, Lin SJ et al. Validation of</a> <a title="AJG_Vol.112.No7 page 135" href="http://viewer.zmags.com/publication/31160122?page=135"> 1094 ORIGINAL CONTRIBUTIONS see related </a> <a title="AJG_Vol.112.No7 page 136" href="http://viewer.zmags.com/publication/31160122?page=136"> whether or not an FGPD patient harbors an undiagn</a> <a title="AJG_Vol.112.No7 page 137" href="http://viewer.zmags.com/publication/31160122?page=137"> 1096 Lloyd et al. a STOMACH * bc </a> <a title="AJG_Vol.112.No7 page 138" href="http://viewer.zmags.com/publication/31160122?page=138"> Review of past medical and family histories reve</a> <a title="AJG_Vol.112.No7 page 139" href="http://viewer.zmags.com/publication/31160122?page=139"> 1098 Lloyd et al. STOMACH Table 1. Clinical</a> <a title="AJG_Vol.112.No7 page 140" href="http://viewer.zmags.com/publication/31160122?page=140"> Incidental Fundic Gland Polyps With Dysplasia </a> <a title="AJG_Vol.112.No7 page 141" href="http://viewer.zmags.com/publication/31160122?page=141"> 1100 Lloyd et al. STOMACH Table 2. Endoscop</a> <a title="AJG_Vol.112.No7 page 142" href="http://viewer.zmags.com/publication/31160122?page=142"> Incidental Fundic Gland Polyps With Dysplasia </a> <a title="AJG_Vol.112.No7 page 143" href="http://viewer.zmags.com/publication/31160122?page=143"> 1102 Lloyd et al. and Canadian Academy of</a> <a title="AJG_Vol.112.No7 page 144" href="http://viewer.zmags.com/publication/31160122?page=144"> ORIGINAL CONTRIBUTIONS 1103 see related ed</a> <a title="AJG_Vol.112.No7 page 145" href="http://viewer.zmags.com/publication/31160122?page=145"> 1104 Wong et al. LIVER ure of renal functio</a> <a title="AJG_Vol.112.No7 page 146" href="http://viewer.zmags.com/publication/31160122?page=146"> AKI and Baseline Serum Creatinine 1105 Tabl</a> <a title="AJG_Vol.112.No7 page 147" href="http://viewer.zmags.com/publication/31160122?page=147"> 1106 Wong et al. LIVER Table 2. Clinical pa</a> <a title="AJG_Vol.112.No7 page 148" href="http://viewer.zmags.com/publication/31160122?page=148"> AKI and Baseline Serum Creatinine 1107 a </a> <a title="AJG_Vol.112.No7 page 149" href="http://viewer.zmags.com/publication/31160122?page=149"> 1108 Wong et al. LIVER Table 3. Comparison </a> <a title="AJG_Vol.112.No7 page 150" href="http://viewer.zmags.com/publication/31160122?page=150"> notable causes of CKD in cirrhosis include IgA ne</a> <a title="AJG_Vol.112.No7 page 151" href="http://viewer.zmags.com/publication/31160122?page=151"> 1110 Wong et al. LIVER contributed to data </a> <a title="AJG_Vol.112.No7 page 152" href="http://viewer.zmags.com/publication/31160122?page=152"> ORIGINAL CONTRIBUTIONS 1111 see related e</a> <a title="AJG_Vol.112.No7 page 153" href="http://viewer.zmags.com/publication/31160122?page=153"> 1112 Lee et al. LIVER Vietnam, Thailand, Ma</a> <a title="AJG_Vol.112.No7 page 154" href="http://viewer.zmags.com/publication/31160122?page=154"> HCV Genotype 6 and HCC Risk 1113 Table 1. B</a> <a title="AJG_Vol.112.No7 page 155" href="http://viewer.zmags.com/publication/31160122?page=155"> 1114 Lee et al. LIVER Table 2. Incidence ra</a> <a title="AJG_Vol.112.No7 page 156" href="http://viewer.zmags.com/publication/31160122?page=156"> ab </a> <a title="AJG_Vol.112.No7 page 157" href="http://viewer.zmags.com/publication/31160122?page=157"> 1116 Lee et al. LIVER Table 3. Crude hazard</a> <a title="AJG_Vol.112.No7 page 158" href="http://viewer.zmags.com/publication/31160122?page=158"> Table 4. Adjusted hazard ratios (HR) of hepatitis</a> <a title="AJG_Vol.112.No7 page 159" href="http://viewer.zmags.com/publication/31160122?page=159"> 1118 Lee et al. LIVER However, HCV is often</a> <a title="AJG_Vol.112.No7 page 160" href="http://viewer.zmags.com/publication/31160122?page=160"> 11. Wasitthankasem R, Vongpunsawad S, Siripon N e</a> <a title="AJG_Vol.112.No7 page 161" href="http://viewer.zmags.com/publication/31160122?page=161"> 1120 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.112.No7 page 162" href="http://viewer.zmags.com/publication/31160122?page=162"> INTRODUCTION The incidence and prevalence of chil</a> <a title="AJG_Vol.112.No7 page 163" href="http://viewer.zmags.com/publication/31160122?page=163"> 1122 Benchimol et al. INFLAMMATORY BOWEL DIS</a> <a title="AJG_Vol.112.No7 page 164" href="http://viewer.zmags.com/publication/31160122?page=164"> Epidemiology of Pediatric IBD in Canada 1123 </a> <a title="AJG_Vol.112.No7 page 165" href="http://viewer.zmags.com/publication/31160122?page=165"> 1124 Benchimol et al. 2 a</a> <a title="AJG_Vol.112.No7 page 166" href="http://viewer.zmags.com/publication/31160122?page=166"> Nova Scotia Ontario </a> <a title="AJG_Vol.112.No7 page 167" href="http://viewer.zmags.com/publication/31160122?page=167"> 1126 Benchimol et al. a Incidence quint</a> <a title="AJG_Vol.112.No7 page 168" href="http://viewer.zmags.com/publication/31160122?page=168"> Epidemiology of Pediatric IBD in Canada 1127 </a> <a title="AJG_Vol.112.No7 page 169" href="http://viewer.zmags.com/publication/31160122?page=169"> 1128 Benchimol et al. a </a> <a title="AJG_Vol.112.No7 page 170" href="http://viewer.zmags.com/publication/31160122?page=170"> Epidemiology of Pediatric IBD in Canada 1129 </a> <a title="AJG_Vol.112.No7 page 171" href="http://viewer.zmags.com/publication/31160122?page=171"> 1130 Benchimol et al. a 70 60 5</a> <a title="AJG_Vol.112.No7 page 172" href="http://viewer.zmags.com/publication/31160122?page=172"> Epidemiology of Pediatric IBD in Canada 1131 </a> <a title="AJG_Vol.112.No7 page 173" href="http://viewer.zmags.com/publication/31160122?page=173"> 1132 Benchimol et al. INFLAMMATORY BOWEL DIS</a> <a title="AJG_Vol.112.No7 page 174" href="http://viewer.zmags.com/publication/31160122?page=174"> interpretation of data; critical revision of the </a> <a title="AJG_Vol.112.No7 page 175" href="http://viewer.zmags.com/publication/31160122?page=175"> 1134 Benchimol et al. INFLAMMATORY BOWEL DIS</a> <a title="AJG_Vol.112.No7 page 176" href="http://viewer.zmags.com/publication/31160122?page=176"> ORIGINAL CONTRIBUTIONS 1135 CME Extracol</a> <a title="AJG_Vol.112.No7 page 177" href="http://viewer.zmags.com/publication/31160122?page=177"> 1136 Chaparro et al. INFLAMMATORY BOWEL DISE</a> <a title="AJG_Vol.112.No7 page 178" href="http://viewer.zmags.com/publication/31160122?page=178"> As it has been suggested that the risk of de</a> <a title="AJG_Vol.112.No7 page 179" href="http://viewer.zmags.com/publication/31160122?page=179"> 1138 Chaparro et al. INFLAMMATORY BOWEL DISE</a> <a title="AJG_Vol.112.No7 page 180" href="http://viewer.zmags.com/publication/31160122?page=180"> Table 5. Multivariate analysis of variables assoc</a> <a title="AJG_Vol.112.No7 page 181" href="http://viewer.zmags.com/publication/31160122?page=181"> 1140 Chaparro et al. INFLAMMATORY BOWEL DISE</a> <a title="AJG_Vol.112.No7 page 182" href="http://viewer.zmags.com/publication/31160122?page=182"> some studies have suggested an association (9,24,</a> <a title="AJG_Vol.112.No7 page 183" href="http://viewer.zmags.com/publication/31160122?page=183"> 1142 Chaparro et al. INFLAMMATORY BOWEL DISE</a> <a title="AJG_Vol.112.No7 page 184" href="http://viewer.zmags.com/publication/31160122?page=184"> 50. Dayharsh GA, Loftus EV Jr, Sandborn WJ et al.</a> <a title="AJG_Vol.112.No7 page 185" href="http://viewer.zmags.com/publication/31160122?page=185"> 1144 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.112.No7 page 186" href="http://viewer.zmags.com/publication/31160122?page=186"> as classification of severity exist (4,5), there </a> <a title="AJG_Vol.112.No7 page 187" href="http://viewer.zmags.com/publication/31160122?page=187"> 1146 Wu et al. PANCREAS AND BILIARY TRACT </a> <a title="AJG_Vol.112.No7 page 188" href="http://viewer.zmags.com/publication/31160122?page=188"> 2015–March 2016 were prospectively identified bas</a> <a title="AJG_Vol.112.No7 page 189" href="http://viewer.zmags.com/publication/31160122?page=189"> 1148 Wu et al. Parameter weights </a> <a title="AJG_Vol.112.No7 page 190" href="http://viewer.zmags.com/publication/31160122?page=190"> Disease Activity in Acute Pancreatitis 1149 </a> <a title="AJG_Vol.112.No7 page 191" href="http://viewer.zmags.com/publication/31160122?page=191"> 1150 Wu et al. Table 2. Individual Parameter</a> <a title="AJG_Vol.112.No7 page 192" href="http://viewer.zmags.com/publication/31160122?page=192"> Disease Activity in Acute Pancreatitis 1151 </a> <a title="AJG_Vol.112.No7 page 193" href="http://viewer.zmags.com/publication/31160122?page=193"> 1152 Wu et al. PANCREAS AND BILIARY TRACT o</a> <a title="AJG_Vol.112.No7 page 194" href="http://viewer.zmags.com/publication/31160122?page=194"> ORIGINAL CONTRIBUTIONS 1153 see related e</a> <a title="AJG_Vol.112.No7 page 195" href="http://viewer.zmags.com/publication/31160122?page=195"> 1154 Crippa et al. PANCREAS AND BILIARY TRAC</a> <a title="AJG_Vol.112.No7 page 196" href="http://viewer.zmags.com/publication/31160122?page=196"> initial diagnosis of IPMN performed by MRI/MRCP t</a> <a title="AJG_Vol.112.No7 page 197" href="http://viewer.zmags.com/publication/31160122?page=197"> 1156 Crippa et al. PANCREAS AND BILIARY TRAC</a> <a title="AJG_Vol.112.No7 page 198" href="http://viewer.zmags.com/publication/31160122?page=198"> Surveillance Beyond 5 Years in Branch-Duct IPMNs </a> <a title="AJG_Vol.112.No7 page 199" href="http://viewer.zmags.com/publication/31160122?page=199"> 1158 Crippa et al. a 4.5 4 3.5 MP</a> <a title="AJG_Vol.112.No7 page 200" href="http://viewer.zmags.com/publication/31160122?page=200"> Surveillance Beyond 5 Years in Branch-Duct IPMNs </a> <a title="AJG_Vol.112.No7 page 201" href="http://viewer.zmags.com/publication/31160122?page=201"> 1160 Crippa et al. PANCREAS AND BILIARY TRAC</a> <a title="AJG_Vol.112.No7 page 202" href="http://viewer.zmags.com/publication/31160122?page=202"> Study Highlights WHAT IS CURRENT KNOWLEDGE ✓ Bra</a> <a title="AJG_Vol.112.No7 page 203" href="http://viewer.zmags.com/publication/31160122?page=203"> 1162 EDITORIAL see related article on pa</a> <a title="AJG_Vol.112.No7 page 204" href="http://viewer.zmags.com/publication/31160122?page=204"> ing overall survival and quality of life (6). Usi</a> <a title="AJG_Vol.112.No7 page 205" href="http://viewer.zmags.com/publication/31160122?page=205"> 1164 Farrell PANCREAS AND BILIARY TRACT sup</a> <a title="AJG_Vol.112.No7 page 206" href="http://viewer.zmags.com/publication/31160122?page=206"> LETTERS TO THE EDITOR 1165 The Risk of G</a> <a title="AJG_Vol.112.No7 page 207" href="http://viewer.zmags.com/publication/31160122?page=207"> 1166 Letters to the Editor lithogenicity a</a> <a title="AJG_Vol.112.No7 page 208" href="http://viewer.zmags.com/publication/31160122?page=208"> study by Lam. In addition, in IBS-C, exces- sive </a> <a title="AJG_Vol.112.No7 page 209" href="http://viewer.zmags.com/publication/31160122?page=209"> 1168 Letters to the Editor of gas measurem</a> <a title="AJG_Vol.112.No7 page 210" href="http://viewer.zmags.com/publication/31160122?page=210"> first-line, but as high as 46% for second- line t</a> <a title="AJG_Vol.112.No7 page 211" href="http://viewer.zmags.com/publication/31160122?page=211"> 1170 Letters to the Editor biotics (condit</a> <a title="AJG_Vol.112.No7 page 212" href="http://viewer.zmags.com/publication/31160122?page=212"> up to 2010. Our group estimated that the prevalen</a> <a title="AJG_Vol.112.No7 page 213" href="http://viewer.zmags.com/publication/31160122?page=213"> 1172 Letters to the Editor UC, an increase</a> <a title="AJG_Vol.112.No7 page 214" href="http://viewer.zmags.com/publication/31160122?page=214"> ANNOUNCEMENTS 1173 CALENDAR OF COURSES, </a> <a title="AJG_Vol.112.No7 page 215" href="http://viewer.zmags.com/publication/31160122?page=215"> 1174 ANNOUNCEMENTS see related editorial </a> <a title="AJG_Vol.112.No7 page 216" href="http://viewer.zmags.com/publication/31160122?page=216"> Fresno, CA 93721 Phone: 559-459-3882 La Jolla Scr</a> <a title="AJG_Vol.112.No7 page 217" href="http://viewer.zmags.com/publication/31160122?page=217"> 1176 Palo Alto Stanford University Hepatology</a> <a title="AJG_Vol.112.No7 page 218" href="http://viewer.zmags.com/publication/31160122?page=218"> 12631 East 17th Ave, Room 7614 Mail Stop B158 Aur</a> <a title="AJG_Vol.112.No7 page 219" 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href="http://viewer.zmags.com/publication/31160122?page=232"> OREGON Portland Oregon Health & Science Universit</a> <a title="AJG_Vol.112.No7 page 233" href="http://viewer.zmags.com/publication/31160122?page=233"> 1192 Division of Gastroenterology & Hepatolog</a> <a title="AJG_Vol.112.No7 page 234" href="http://viewer.zmags.com/publication/31160122?page=234"> Medical University of South Carolina Advanced End</a> <a title="AJG_Vol.112.No7 page 235" href="http://viewer.zmags.com/publication/31160122?page=235"> 1194 Dallas, TX 75390 Phone: 214-645-6415 Uni</a> <a title="AJG_Vol.112.No7 page 236" href="http://viewer.zmags.com/publication/31160122?page=236"> Division of Gastroenterology 2401 South 31st Stre</a> <a title="AJG_Vol.112.No7 page 237" href="http://viewer.zmags.com/publication/31160122?page=237"> 1196 Seattle, WA 98195-6424 Phone: 206-221-92</a> <a title="AJG_Vol.112.No7 page 238" href="http://viewer.zmags.com/publication/31160122?page=238"> University of Alberta, Edmonton IBD Brendan Hallo</a> <a title="AJG_Vol.112.No7 page 239" href="http://viewer.zmags.com/publication/31160122?page=239"> 1198 Western University, London Gastroenterol</a> <a title="AJG_Vol.112.No7 page 240" href="http://viewer.zmags.com/publication/31160122?page=240"> COLORADO Pueblo RMOPTI/Parkview Medical Center Ga</a> <a title="AJG_Vol.112.No7 page 241" href="http://viewer.zmags.com/publication/31160122?page=241"> 1200 188 Fries Mill Road, Suite N-1 Turnersvi</a> <a title="AJG_Vol.112.No7 page 242" href="http://viewer.zmags.com/publication/31160122?page=242"> Lucile Packard Children's Hospital 750 Welch Road</a> <a title="AJG_Vol.112.No7 page 243" href="http://viewer.zmags.com/publication/31160122?page=243"> 1202 Orlando University of Florida (Orlando) </a> <a title="AJG_Vol.112.No7 page 244" href="http://viewer.zmags.com/publication/31160122?page=244"> Boston Children's Hospital 300 Longwood Avenue Bo</a> <a title="AJG_Vol.112.No7 page 245" href="http://viewer.zmags.com/publication/31160122?page=245"> 1204 Brooklyn SUNY Health Sciences Center at </a> <a title="AJG_Vol.112.No7 page 246" href="http://viewer.zmags.com/publication/31160122?page=246"> Cleveland Case Western Reserve Univ/Univ Hospital</a> <a title="AJG_Vol.112.No7 page 247" href="http://viewer.zmags.com/publication/31160122?page=247"> 1206 CC1010.00 Houston, TX 77030 Phone: 856-</a> <a title="AJG_Vol.112.No7 page 248" href="http://viewer.zmags.com/publication/31160122?page=248"> ERRATA, CORRIGENDA AND RETRACTIONS 1207 Corr</a> <a title="AJG_Vol.112.No7 page 249" href="http://viewer.zmags.com/publication/31160122?page=249"> 1208 Errata, Corrigenda and Retractions Co</a> <a title="AJG_Vol.112.No7 page 250" href="http://viewer.zmags.com/publication/31160122?page=250"> Errata, Corrigenda and Retractions 1209 Co</a> <a title="AJG_Vol.112.No7 page 251" href="http://viewer.zmags.com/publication/31160122?page=251"> 1210 Errata, Corrigenda and Retractions Co</a> <a title="AJG_Vol.112.No7 page 252" href="http://viewer.zmags.com/publication/31160122?page=252"> American College of Gastroenterology & World Gast</a> <a title="AJG_Vol.112.No7 page 253" href="http://viewer.zmags.com/publication/31160122?page=253"> CLASSIFIEDS Tired of practicing institutiona</a> <a title="AJG_Vol.112.No7 page 254" href="http://viewer.zmags.com/publication/31160122?page=254"> GASTROENTEROLOGY OPPORTUNITY Mercy Health Muskeg</a> <a title="AJG_Vol.112.No7 page 255" href="http://viewer.zmags.com/publication/31160122?page=255"> CHIEF, DIVISION OF GASTROENTEROLOGY AND HEPATOLOG</a> <a title="AJG_Vol.112.No7 page 256" href="http://viewer.zmags.com/publication/31160122?page=256"> IMPORTANT SAFETY INFORMATION SUPREP® Bowel Prep K</a> <a title="AJG_Vol.112.No7 page 257" href="http://viewer.zmags.com/publication/31160122?page=257"> #1 MOST PRESCRIBED, BRANDED BOWEL PREP KIT1 A</a>