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<br /> Volume 109 Number 1 JANuArY 2014<br /> www.amjgastro.com<br /> official publication of the american college of gastroenterology<br /> leading articles of the month<br /> Clinical and Systematic Reviews<br /> 23 The Role of Thiopurines in Reducing the Need for Surgical<br /> Resection in Crohn’s Disease: A Systematic Review<br /> and Meta-Analysis CME<br /> S. Chatu, V. Subramanian, S. Saxena and R.C.G. Pollok<br /> Esophagus<br /> 52 Objective Manometric Criteria for the Rumination Syndrome<br /> B.F. Kessing, A.J. Bredenoord and A.J.P.M. Smout<br /> Stomach<br /> 60 Effect of Helicobacter pylori Eradication on Metachronous<br /> Recurrence After Endoscopic Resection of Gastric Neoplasm<br /> S.E. Bae, H.-Y. Jung, J. Kang, Y.S. Park, S. Baek, J.-H. Jung, J.Y. Choi,<br /> M.-Y. Kim, J.Y. Ahn, K.-S. Choi, D.H. Kim, J.H. Lee, K.D. Choi, H.J. Song,<b<a title="AJG_Vol.109_No.5 page 1" href="http://viewer.zmags.com/publication/35da31e7?page=1"> Volume 109 Number 1 JANuArY 2014 www.amjgastro.co</a> <a title="AJG_Vol.109_No.5 page 2" href="http://viewer.zmags.com/publication/35da31e7?page=2"> Volume 109 Number 5 may 2014 www.amjgastro.com </a> <a title="AJG_Vol.109_No.5 page 3" href="http://viewer.zmags.com/publication/35da31e7?page=3"> Superior cleansing* *Demonstr</a> <a title="AJG_Vol.109_No.5 page 4" href="http://viewer.zmags.com/publication/35da31e7?page=4"> Lowest volume of active prep solution— only 10 oz</a> <a title="AJG_Vol.109_No.5 page 5" href="http://viewer.zmags.com/publication/35da31e7?page=5"> The following is a brief summary only; see full P</a> <a title="AJG_Vol.109_No.5 page 6" href="http://viewer.zmags.com/publication/35da31e7?page=6"> RetroView ™ GivesYouThe Power To See It. One lo</a> <a title="AJG_Vol.109_No.5 page 7" href="http://viewer.zmags.com/publication/35da31e7?page=7"> www.amjgastro.com The American Journal of</a> <a title="AJG_Vol.109_No.5 page 8" href="http://viewer.zmags.com/publication/35da31e7?page=8"> </a> <a title="AJG_Vol.109_No.5 page 9" href="http://viewer.zmags.com/publication/35da31e7?page=9"> COMING SOON FROM TAKEDA PHARMA</a> <a title="AJG_Vol.109_No.5 page 10" href="http://viewer.zmags.com/publication/35da31e7?page=10"> official publication of the american college</a> <a title="AJG_Vol.109_No.5 page 11" href="http://viewer.zmags.com/publication/35da31e7?page=11"> There are Hidden Problems in Your GI Testing Meth</a> <a title="AJG_Vol.109_No.5 page 12" href="http://viewer.zmags.com/publication/35da31e7?page=12"> </a> <a title="AJG_Vol.109_No.5 page 13" href="http://viewer.zmags.com/publication/35da31e7?page=13"> References: 1. Li K, Foy E, Ferreon JC, et al. Im</a> <a title="AJG_Vol.109_No.5 page 14" href="http://viewer.zmags.com/publication/35da31e7?page=14"> HCV: Master of Elusion The human body does everyt</a> <a title="AJG_Vol.109_No.5 page 15" href="http://viewer.zmags.com/publication/35da31e7?page=15"> Donnatal® has been delivering symptomatic relief </a> <a title="AJG_Vol.109_No.5 page 16" href="http://viewer.zmags.com/publication/35da31e7?page=16"> a short reflux event in a GerD patient captured wi</a> <a title="AJG_Vol.109_No.5 page 17" href="http://viewer.zmags.com/publication/35da31e7?page=17"> CONTENTS </a> <a title="AJG_Vol.109_No.5 page 18" href="http://viewer.zmags.com/publication/35da31e7?page=18"> www.amjgastro.com Plotted SNPs (</a> <a title="AJG_Vol.109_No.5 page 19" href="http://viewer.zmags.com/publication/35da31e7?page=19"> Important Safety Information for HUMIRA® (adalimu</a> <a title="AJG_Vol.109_No.5 page 20" href="http://viewer.zmags.com/publication/35da31e7?page=20"> In patients with moderate to severe Crohn's disea</a> <a title="AJG_Vol.109_No.5 page 21" href="http://viewer.zmags.com/publication/35da31e7?page=21"> HUMIRA® (adalimumab) </a> <a title="AJG_Vol.109_No.5 page 22" href="http://viewer.zmags.com/publication/35da31e7?page=22"> Consider discontinuation of HUMIRA therapy in pat</a> <a title="AJG_Vol.109_No.5 page 23" href="http://viewer.zmags.com/publication/35da31e7?page=23"> other biologic DMARDS (e.g., anakinra and abatace</a> <a title="AJG_Vol.109_No.5 page 24" href="http://viewer.zmags.com/publication/35da31e7?page=24"> Pleased to meet you. We're Intercept — a differe</a> <a title="AJG_Vol.109_No.5 page 25" href="http://viewer.zmags.com/publication/35da31e7?page=25"> For patients with active, mild to moderate ulcera</a> <a title="AJG_Vol.109_No.5 page 26" href="http://viewer.zmags.com/publication/35da31e7?page=26"> To request samples and get real-time answers on p</a> <a title="AJG_Vol.109_No.5 page 27" href="http://viewer.zmags.com/publication/35da31e7?page=27"> BRIEF SUMMARY: Consult the Full Prescribing Infor</a> <a title="AJG_Vol.109_No.5 page 28" href="http://viewer.zmags.com/publication/35da31e7?page=28"> not always possible to reliably estimate their fr</a> <a title="AJG_Vol.109_No.5 page 29" href="http://viewer.zmags.com/publication/35da31e7?page=29"> Personality rights of THE WRIGHT BR</a> <a title="AJG_Vol.109_No.5 page 30" href="http://viewer.zmags.com/publication/35da31e7?page=30"> CHANGE THE WAY YOU TREAT HCV GT 1 PATIENTS A 12-</a> <a title="AJG_Vol.109_No.5 page 31" href="http://viewer.zmags.com/publication/35da31e7?page=31"> Dosing information for patients with HCV GT 1 or </a> <a title="AJG_Vol.109_No.5 page 32" href="http://viewer.zmags.com/publication/35da31e7?page=32"> SOVALDI® (sofosbuvir) Brief summary of full Pr</a> <a title="AJG_Vol.109_No.5 page 33" href="http://viewer.zmags.com/publication/35da31e7?page=33"> Brief Summary (cont.) Table 2 Percentage of Sub</a> <a title="AJG_Vol.109_No.5 page 34" href="http://viewer.zmags.com/publication/35da31e7?page=34"> BRIEF SUMMARY Please see package insert for </a> <a title="AJG_Vol.109_No.5 page 35" href="http://viewer.zmags.com/publication/35da31e7?page=35"> InActive,MildtoModerateUlcerativeColitis(UC) POWE</a> <a title="AJG_Vol.109_No.5 page 36" href="http://viewer.zmags.com/publication/35da31e7?page=36"> nature publishing group </a> <a title="AJG_Vol.109_No.5 page 37" href="http://viewer.zmags.com/publication/35da31e7?page=37"> 618 The red secTion </a> <a title="AJG_Vol.109_No.5 page 38" href="http://viewer.zmags.com/publication/35da31e7?page=38"> The red secTion 619 novel role of the </a> <a title="AJG_Vol.109_No.5 page 39" href="http://viewer.zmags.com/publication/35da31e7?page=39"> 620 THE RED SECTION </a> <a title="AJG_Vol.109_No.5 page 40" href="http://viewer.zmags.com/publication/35da31e7?page=40"> The drug development and approval process The mai</a> <a title="AJG_Vol.109_No.5 page 41" href="http://viewer.zmags.com/publication/35da31e7?page=41"> 622 THE RED SECTION on the approvability</a> <a title="AJG_Vol.109_No.5 page 42" href="http://viewer.zmags.com/publication/35da31e7?page=42"> “written request” may only be issued by the FDA p</a> <a title="AJG_Vol.109_No.5 page 43" href="http://viewer.zmags.com/publication/35da31e7?page=43"> 624 THE RED SECTION </a> <a title="AJG_Vol.109_No.5 page 44" href="http://viewer.zmags.com/publication/35da31e7?page=44"> 700 600 500 Millions of US dollars 400 30</a> <a title="AJG_Vol.109_No.5 page 45" href="http://viewer.zmags.com/publication/35da31e7?page=45"> 626 The red secTion </a> <a title="AJG_Vol.109_No.5 page 46" href="http://viewer.zmags.com/publication/35da31e7?page=46"> nature publishing group </a> <a title="AJG_Vol.109_No.5 page 47" href="http://viewer.zmags.com/publication/35da31e7?page=47"> 628 CLINICAL AND SYSTEMATIC REVIEWS </a> <a title="AJG_Vol.109_No.5 page 48" href="http://viewer.zmags.com/publication/35da31e7?page=48"> discussion of treatment and understanding of the </a> <a title="AJG_Vol.109_No.5 page 49" href="http://viewer.zmags.com/publication/35da31e7?page=49"> 630 Muir Population Recommended regimen</a> <a title="AJG_Vol.109_No.5 page 50" href="http://viewer.zmags.com/publication/35da31e7?page=50"> Treatment for Hepatitis C 631 Table 1. O</a> <a title="AJG_Vol.109_No.5 page 51" href="http://viewer.zmags.com/publication/35da31e7?page=51"> 632 Muir REVIEW patients who would have be</a> <a title="AJG_Vol.109_No.5 page 52" href="http://viewer.zmags.com/publication/35da31e7?page=52"> Table 2. Outcomes for genotype 2 infection with s</a> <a title="AJG_Vol.109_No.5 page 53" href="http://viewer.zmags.com/publication/35da31e7?page=53"> 634 Muir REVIEW Genotype 4 infection The r</a> <a title="AJG_Vol.109_No.5 page 54" href="http://viewer.zmags.com/publication/35da31e7?page=54"> 10. Ditah I, Ditah F, Devaki P et al. The Changin</a> <a title="AJG_Vol.109_No.5 page 55" href="http://viewer.zmags.com/publication/35da31e7?page=55"> 636 CLINICAL AND SYSTEMATIC REVIEWS </a> <a title="AJG_Vol.109_No.5 page 56" href="http://viewer.zmags.com/publication/35da31e7?page=56"> nature publishing group </a> <a title="AJG_Vol.109_No.5 page 57" href="http://viewer.zmags.com/publication/35da31e7?page=57"> 638 Henderson et al. REVIEW 40 and 60% of </a> <a title="AJG_Vol.109_No.5 page 58" href="http://viewer.zmags.com/publication/35da31e7?page=58"> Calprotectin During Diagnosis of Pediatric IBD </a> <a title="AJG_Vol.109_No.5 page 59" href="http://viewer.zmags.com/publication/35da31e7?page=59"> 640 Henderson et al. REVIEW Box 1. (Contin</a> <a title="AJG_Vol.109_No.5 page 60" href="http://viewer.zmags.com/publication/35da31e7?page=60"> evident in the manuscript. Of note, only one pape</a> <a title="AJG_Vol.109_No.5 page 61" href="http://viewer.zmags.com/publication/35da31e7?page=61"> 642 Henderson et al. REVIEW sensitivity (9</a> <a title="AJG_Vol.109_No.5 page 62" href="http://viewer.zmags.com/publication/35da31e7?page=62"> Summary ROC curve 1.0 0.8 Sensitivity 0.6 </a> <a title="AJG_Vol.109_No.5 page 63" href="http://viewer.zmags.com/publication/35da31e7?page=63"> 644 Henderson et al. REVIEW Conclusion It </a> <a title="AJG_Vol.109_No.5 page 64" href="http://viewer.zmags.com/publication/35da31e7?page=64"> 24. Fedak D, Pawlica D, Ciecko-Michalska I et al.</a> <a title="AJG_Vol.109_No.5 page 65" href="http://viewer.zmags.com/publication/35da31e7?page=65"> 646 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.109_No.5 page 66" href="http://viewer.zmags.com/publication/35da31e7?page=66"> regulate downstream immune events and effector ce</a> <a title="AJG_Vol.109_No.5 page 67" href="http://viewer.zmags.com/publication/35da31e7?page=67"> 648 Lexmond et al. ESOPHAGUS RESULTS The C</a> <a title="AJG_Vol.109_No.5 page 68" href="http://viewer.zmags.com/publication/35da31e7?page=68"> Involvement of the iNKT Cell Pathway in EoE 6</a> <a title="AJG_Vol.109_No.5 page 69" href="http://viewer.zmags.com/publication/35da31e7?page=69"> 650 Lexmond et al. ESOPHAGUS Table 1. Symp</a> <a title="AJG_Vol.109_No.5 page 70" href="http://viewer.zmags.com/publication/35da31e7?page=70"> Involvement of the iNKT Cell Pathway in EoE 6</a> <a title="AJG_Vol.109_No.5 page 71" href="http://viewer.zmags.com/publication/35da31e7?page=71"> 652 Lexmond et al. ESOPHAGUS Esophageal eo</a> <a title="AJG_Vol.109_No.5 page 72" href="http://viewer.zmags.com/publication/35da31e7?page=72"> Involvement of the iNKT Cell Pathway in EoE 6</a> <a title="AJG_Vol.109_No.5 page 73" href="http://viewer.zmags.com/publication/35da31e7?page=73"> 654 Lexmond et al. ESOPHAGUS Table 3. Pred</a> <a title="AJG_Vol.109_No.5 page 74" href="http://viewer.zmags.com/publication/35da31e7?page=74"> tion phase of disease. Specifically, Scanlon et a</a> <a title="AJG_Vol.109_No.5 page 75" href="http://viewer.zmags.com/publication/35da31e7?page=75"> 656 Lexmond et al. ESOPHAGUS esophageal in</a> <a title="AJG_Vol.109_No.5 page 76" href="http://viewer.zmags.com/publication/35da31e7?page=76"> 28. Kim CH, Johnston B, Butcher EC. Trafficking m</a> <a title="AJG_Vol.109_No.5 page 77" href="http://viewer.zmags.com/publication/35da31e7?page=77"> 658 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.109_No.5 page 78" href="http://viewer.zmags.com/publication/35da31e7?page=78"> protect against gastroesophageal reflux (GER) des</a> <a title="AJG_Vol.109_No.5 page 79" href="http://viewer.zmags.com/publication/35da31e7?page=79"> 660 Curcic et al. ESOPHAGUS HRM catheter p</a> <a title="AJG_Vol.109_No.5 page 80" href="http://viewer.zmags.com/publication/35da31e7?page=80"> EGJ Structure and Function 661 t = 0 s </a> <a title="AJG_Vol.109_No.5 page 81" href="http://viewer.zmags.com/publication/35da31e7?page=81"> 662 Curcic et al. ESOPHAGUS Distance from n</a> <a title="AJG_Vol.109_No.5 page 82" href="http://viewer.zmags.com/publication/35da31e7?page=82"> EGJ Structure and Function 663 Table 2. S</a> <a title="AJG_Vol.109_No.5 page 83" href="http://viewer.zmags.com/publication/35da31e7?page=83"> 664 Curcic et al. Mean esophago-gastric</a> <a title="AJG_Vol.109_No.5 page 84" href="http://viewer.zmags.com/publication/35da31e7?page=84"> EGJ Structure and Function 665 Ellipso</a> <a title="AJG_Vol.109_No.5 page 85" href="http://viewer.zmags.com/publication/35da31e7?page=85"> 666 Curcic et al. ESOPHAGUS of esophagogas</a> <a title="AJG_Vol.109_No.5 page 86" href="http://viewer.zmags.com/publication/35da31e7?page=86"> 3. Holloway RH, Hongo M, Berger K et al. Gastric</a> <a title="AJG_Vol.109_No.5 page 87" href="http://viewer.zmags.com/publication/35da31e7?page=87"> 668 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.109_No.5 page 88" href="http://viewer.zmags.com/publication/35da31e7?page=88"> can be induced in murine models with antigen chal</a> <a title="AJG_Vol.109_No.5 page 89" href="http://viewer.zmags.com/publication/35da31e7?page=89"> 670 Jensen et al. ESOPHAGUS Statistical an</a> <a title="AJG_Vol.109_No.5 page 90" href="http://viewer.zmags.com/publication/35da31e7?page=90"> Table 1. Demographic characteristics, clinical sy</a> <a title="AJG_Vol.109_No.5 page 91" href="http://viewer.zmags.com/publication/35da31e7?page=91"> 672 Jensen et al. ESOPHAGUS Table 2. Chara</a> <a title="AJG_Vol.109_No.5 page 92" href="http://viewer.zmags.com/publication/35da31e7?page=92"> Esophageal Eosinophilia and Population Density </a> <a title="AJG_Vol.109_No.5 page 93" href="http://viewer.zmags.com/publication/35da31e7?page=93"> 674 Jensen et al. ESOPHAGUS and 10 µm), wh</a> <a title="AJG_Vol.109_No.5 page 94" href="http://viewer.zmags.com/publication/35da31e7?page=94"> Study Highlights WHAT IS CURRENT KNOWLEDGE 3Eosi</a> <a title="AJG_Vol.109_No.5 page 95" href="http://viewer.zmags.com/publication/35da31e7?page=95"> 676 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.109_No.5 page 96" href="http://viewer.zmags.com/publication/35da31e7?page=96"> practice change and to address our perception of </a> <a title="AJG_Vol.109_No.5 page 97" href="http://viewer.zmags.com/publication/35da31e7?page=97"> 678 Levy et al. ENDOSCOPY Table 1. Adverse</a> <a title="AJG_Vol.109_No.5 page 98" href="http://viewer.zmags.com/publication/35da31e7?page=98"> linear EUS (n = 502; 100%). Among 87 (17.3%) pati</a> <a title="AJG_Vol.109_No.5 page 99" href="http://viewer.zmags.com/publication/35da31e7?page=99"> 680 Levy et al. ENDOSCOPY Table 5. Risk fa</a> <a title="AJG_Vol.109_No.5 page 100" href="http://viewer.zmags.com/publication/35da31e7?page=100"> 0.0008, respectively). The pain was classified as</a> <a title="AJG_Vol.109_No.5 page 101" href="http://viewer.zmags.com/publication/35da31e7?page=101"> 682 Levy et al. ENDOSCOPY Table 8. Risk fa</a> <a title="AJG_Vol.109_No.5 page 102" href="http://viewer.zmags.com/publication/35da31e7?page=102"> routine endoscopy and the additional procedures w</a> <a title="AJG_Vol.109_No.5 page 103" href="http://viewer.zmags.com/publication/35da31e7?page=103"> 684 Levy et al. ENDOSCOPY bleeding. Furthe</a> <a title="AJG_Vol.109_No.5 page 104" href="http://viewer.zmags.com/publication/35da31e7?page=104"> 28. Bournet B, Migueres I, Delacroix M et al. Ear</a> <a title="AJG_Vol.109_No.5 page 105" href="http://viewer.zmags.com/publication/35da31e7?page=105"> 686 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.109_No.5 page 106" href="http://viewer.zmags.com/publication/35da31e7?page=106"> Sodium picosulfate with magnesium oxide is a co</a> <a title="AJG_Vol.109_No.5 page 107" href="http://viewer.zmags.com/publication/35da31e7?page=107"> 688 Weir et al. ENDOSCOPY Table 1. Composi</a> <a title="AJG_Vol.109_No.5 page 108" href="http://viewer.zmags.com/publication/35da31e7?page=108"> Study drug prescriptions during the accrual perio</a> <a title="AJG_Vol.109_No.5 page 109" href="http://viewer.zmags.com/publication/35da31e7?page=109"> 690 Weir et al. ENDOSCOPY Table 2. Baselin</a> <a title="AJG_Vol.109_No.5 page 110" href="http://viewer.zmags.com/publication/35da31e7?page=110"> Sodium Picosulfate and Hyponatremia 691 T</a> <a title="AJG_Vol.109_No.5 page 111" href="http://viewer.zmags.com/publication/35da31e7?page=111"> 692 Weir et al. ENDOSCOPY There are sev</a> <a title="AJG_Vol.109_No.5 page 112" href="http://viewer.zmags.com/publication/35da31e7?page=112"> laboratory database, and the team at London Healt</a> <a title="AJG_Vol.109_No.5 page 113" href="http://viewer.zmags.com/publication/35da31e7?page=113"> 694 Weir et al. ENDOSCOPY 29. Jha P, Deboe</a> <a title="AJG_Vol.109_No.5 page 114" href="http://viewer.zmags.com/publication/35da31e7?page=114"> nature publishing group </a> <a title="AJG_Vol.109_No.5 page 115" href="http://viewer.zmags.com/publication/35da31e7?page=115"> 696 Price et al. LIVER persons, mounting e</a> <a title="AJG_Vol.109_No.5 page 116" href="http://viewer.zmags.com/publication/35da31e7?page=116"> Laboratory testing and definitions For SNP genotyp</a> <a title="AJG_Vol.109_No.5 page 117" href="http://viewer.zmags.com/publication/35da31e7?page=117"> 698 Price et al. LIVER Table 1. Characteri</a> <a title="AJG_Vol.109_No.5 page 118" href="http://viewer.zmags.com/publication/35da31e7?page=118"> Fatty Liver and HIV Infection 699 Table 2</a> <a title="AJG_Vol.109_No.5 page 119" href="http://viewer.zmags.com/publication/35da31e7?page=119"> 700 Price et al. LIVER Table 2. Continued </a> <a title="AJG_Vol.109_No.5 page 120" href="http://viewer.zmags.com/publication/35da31e7?page=120"> Fatty Liver and HIV Infection 701 Table 4</a> <a title="AJG_Vol.109_No.5 page 121" href="http://viewer.zmags.com/publication/35da31e7?page=121"> 702 Price et al. LIVER were dideoxynucleos</a> <a title="AJG_Vol.109_No.5 page 122" href="http://viewer.zmags.com/publication/35da31e7?page=122"> of nonalcoholic fatty liver disease, although no </a> <a title="AJG_Vol.109_No.5 page 123" href="http://viewer.zmags.com/publication/35da31e7?page=123"> 704 Price et al. LIVER 2. Bica I, McGover</a> <a title="AJG_Vol.109_No.5 page 124" href="http://viewer.zmags.com/publication/35da31e7?page=124"> nature publishing group </a> <a title="AJG_Vol.109_No.5 page 125" href="http://viewer.zmags.com/publication/35da31e7?page=125"> 706 Vester-Andersen et al. INFLAMMATORY BOW</a> <a title="AJG_Vol.109_No.5 page 126" href="http://viewer.zmags.com/publication/35da31e7?page=126"> Disease Course in IBD: A Population-Based Study </a> <a title="AJG_Vol.109_No.5 page 127" href="http://viewer.zmags.com/publication/35da31e7?page=127"> Nonincident N =4 CD patients diagnosed</a> <a title="AJG_Vol.109_No.5 page 128" href="http://viewer.zmags.com/publication/35da31e7?page=128"> Disease Course in IBD: A Population-Based Study </a> <a title="AJG_Vol.109_No.5 page 129" href="http://viewer.zmags.com/publication/35da31e7?page=129"> 710 Vester-Andersen et al. malignant m</a> <a title="AJG_Vol.109_No.5 page 130" href="http://viewer.zmags.com/publication/35da31e7?page=130"> Disease Course in IBD: A Population-Based Study </a> <a title="AJG_Vol.109_No.5 page 131" href="http://viewer.zmags.com/publication/35da31e7?page=131"> 712 Vester-Andersen et al. INFLAMMATORY BOW</a> <a title="AJG_Vol.109_No.5 page 132" href="http://viewer.zmags.com/publication/35da31e7?page=132"> CONFLICT OF INTEREST Guarantor of the article: Fl</a> <a title="AJG_Vol.109_No.5 page 133" href="http://viewer.zmags.com/publication/35da31e7?page=133"> 714 Vester-Andersen et al. INFLAMMATORY BOW</a> <a title="AJG_Vol.109_No.5 page 134" href="http://viewer.zmags.com/publication/35da31e7?page=134"> nature publishing group </a> <a title="AJG_Vol.109_No.5 page 135" href="http://viewer.zmags.com/publication/35da31e7?page=135"> 716 van den Broek et al. INFLAMMATORY BOWEL</a> <a title="AJG_Vol.109_No.5 page 136" href="http://viewer.zmags.com/publication/35da31e7?page=136"> random biopsies only in relation to the number of</a> <a title="AJG_Vol.109_No.5 page 137" href="http://viewer.zmags.com/publication/35da31e7?page=137"> 718 van den Broek et al. INFLAMMATORY BOWEL</a> <a title="AJG_Vol.109_No.5 page 138" href="http://viewer.zmags.com/publication/35da31e7?page=138"> Low Yield of Random Biopsies in UC 719 </a> <a title="AJG_Vol.109_No.5 page 139" href="http://viewer.zmags.com/publication/35da31e7?page=139"> 720 van den Broek et al. INFLAMMATORY BOWEL</a> <a title="AJG_Vol.109_No.5 page 140" href="http://viewer.zmags.com/publication/35da31e7?page=140"> biopsies were mentioned. The presence of these vi</a> <a title="AJG_Vol.109_No.5 page 141" href="http://viewer.zmags.com/publication/35da31e7?page=141"> 722 van den Broek et al. of UC patient</a> <a title="AJG_Vol.109_No.5 page 142" href="http://viewer.zmags.com/publication/35da31e7?page=142"> nature publishing group </a> <a title="AJG_Vol.109_No.5 page 143" href="http://viewer.zmags.com/publication/35da31e7?page=143"> 724 Qumseya et al. FUNCTIONAL GI DISORDERS </a> <a title="AJG_Vol.109_No.5 page 144" href="http://viewer.zmags.com/publication/35da31e7?page=144"> Table 1. Baseline characteristics for the 1,352 p</a> <a title="AJG_Vol.109_No.5 page 145" href="http://viewer.zmags.com/publication/35da31e7?page=145"> 726 Qumseya et al. Prevalence of IBS I</a> <a title="AJG_Vol.109_No.5 page 146" href="http://viewer.zmags.com/publication/35da31e7?page=146"> Table 4. Prevalence of IBS and its subtypes by ge</a> <a title="AJG_Vol.109_No.5 page 147" href="http://viewer.zmags.com/publication/35da31e7?page=147"> 728 Qumseya et al. FUNCTIONAL GI DISORDERS </a> <a title="AJG_Vol.109_No.5 page 148" href="http://viewer.zmags.com/publication/35da31e7?page=148"> Study Highlights WHAT IS CURRENT KNOWLEDGE 3Prev</a> <a title="AJG_Vol.109_No.5 page 149" href="http://viewer.zmags.com/publication/35da31e7?page=149"> 730 Qumseya et al. FUNCTIONAL GI DISORDERS </a> <a title="AJG_Vol.109_No.5 page 150" href="http://viewer.zmags.com/publication/35da31e7?page=150"> APPENDIX 2 Study questionnaire in English and A</a> <a title="AJG_Vol.109_No.5 page 151" href="http://viewer.zmags.com/publication/35da31e7?page=151"> 732 Qumseya et al. FUNCTIONAL GI DISORDERS </a> <a title="AJG_Vol.109_No.5 page 152" href="http://viewer.zmags.com/publication/35da31e7?page=152"> © 2014 by the American College of Gastroenterolog</a> <a title="AJG_Vol.109_No.5 page 153" href="http://viewer.zmags.com/publication/35da31e7?page=153"> 734 Qumseya et al. FUNCTIONAL GI DISORDERS </a> <a title="AJG_Vol.109_No.5 page 154" href="http://viewer.zmags.com/publication/35da31e7?page=154"> Prevalence of IBS in Palestine 735 FUNCTIONA</a> <a title="AJG_Vol.109_No.5 page 155" href="http://viewer.zmags.com/publication/35da31e7?page=155"> 736 Qumseya et al. FUNCTIONAL GI DISORDERS </a> <a title="AJG_Vol.109_No.5 page 156" href="http://viewer.zmags.com/publication/35da31e7?page=156"> © 2014 by the American College of Gastroenterolog</a> <a title="AJG_Vol.109_No.5 page 157" href="http://viewer.zmags.com/publication/35da31e7?page=157"> 738 Qumseya et al. FUNCTIONAL GI DISORDERS </a> <a title="AJG_Vol.109_No.5 page 158" href="http://viewer.zmags.com/publication/35da31e7?page=158"> Prevalence of IBS in Palestine 739 FUNCTIONA</a> <a title="AJG_Vol.109_No.5 page 159" href="http://viewer.zmags.com/publication/35da31e7?page=159"> 740 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.109_No.5 page 160" href="http://viewer.zmags.com/publication/35da31e7?page=160"> nature publishing group </a> <a title="AJG_Vol.109_No.5 page 161" href="http://viewer.zmags.com/publication/35da31e7?page=161"> 742 Kabbani et al. COLON/SMALL BOWEL gener</a> <a title="AJG_Vol.109_No.5 page 162" href="http://viewer.zmags.com/publication/35da31e7?page=162"> Symptoms responsive to GFD </a> <a title="AJG_Vol.109_No.5 page 163" href="http://viewer.zmags.com/publication/35da31e7?page=163"> 744 Kabbani et al. COLON/SMALL BOWEL and w</a> <a title="AJG_Vol.109_No.5 page 164" href="http://viewer.zmags.com/publication/35da31e7?page=164"> of gluten-responsive symptoms and negative tTG or</a> <a title="AJG_Vol.109_No.5 page 165" href="http://viewer.zmags.com/publication/35da31e7?page=165"> 746 Kabbani et al. COLON/SMALL BOWEL tTG o</a> <a title="AJG_Vol.109_No.5 page 166" href="http://viewer.zmags.com/publication/35da31e7?page=166"> nature publishing group </a> <a title="AJG_Vol.109_No.5 page 167" href="http://viewer.zmags.com/publication/35da31e7?page=167"> 748 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.109_No.5 page 168" href="http://viewer.zmags.com/publication/35da31e7?page=168"> disease (15–17). However, it is unknown whether e</a> <a title="AJG_Vol.109_No.5 page 169" href="http://viewer.zmags.com/publication/35da31e7?page=169"> 750 Galipeau et al. mass spectrum. The</a> <a title="AJG_Vol.109_No.5 page 170" href="http://viewer.zmags.com/publication/35da31e7?page=170"> calculated as the average over a 2-h period and e</a> <a title="AJG_Vol.109_No.5 page 171" href="http://viewer.zmags.com/publication/35da31e7?page=171"> 752 Galipeau et al. intermediate betwe</a> <a title="AJG_Vol.109_No.5 page 172" href="http://viewer.zmags.com/publication/35da31e7?page=172"> Elafin and Celiac Disease 753 51Cr-EDTA</a> <a title="AJG_Vol.109_No.5 page 173" href="http://viewer.zmags.com/publication/35da31e7?page=173"> 754 Galipeau et al. 0.4 0.3 0.2 </a> <a title="AJG_Vol.109_No.5 page 174" href="http://viewer.zmags.com/publication/35da31e7?page=174"> elafin administration affected these paramete</a> <a title="AJG_Vol.109_No.5 page 175" href="http://viewer.zmags.com/publication/35da31e7?page=175"> 756 Galipeau et al. COLON/SMALL BOWEL 2. </a> <a title="AJG_Vol.109_No.5 page 176" href="http://viewer.zmags.com/publication/35da31e7?page=176"> nature publishing group </a> <a title="AJG_Vol.109_No.5 page 177" href="http://viewer.zmags.com/publication/35da31e7?page=177"> 758 West et al. COLON/SMALL BOWEL increase</a> <a title="AJG_Vol.109_No.5 page 178" href="http://viewer.zmags.com/publication/35da31e7?page=178"> in addition to one diagnostic record of either CD</a> <a title="AJG_Vol.109_No.5 page 179" href="http://viewer.zmags.com/publication/35da31e7?page=179"> 760 West et al. COLON/SMALL BOWEL Table 1.</a> <a title="AJG_Vol.109_No.5 page 180" href="http://viewer.zmags.com/publication/35da31e7?page=180"> Incidence and Prevalence of CD and DH 761 </a> <a title="AJG_Vol.109_No.5 page 181" href="http://viewer.zmags.com/publication/35da31e7?page=181"> 762 West et al. </a> <a title="AJG_Vol.109_No.5 page 182" href="http://viewer.zmags.com/publication/35da31e7?page=182"> Incidence and Prevalence of CD and DH 763 </a> <a title="AJG_Vol.109_No.5 page 183" href="http://viewer.zmags.com/publication/35da31e7?page=183"> 764 West et al. COLON/SMALL BOWEL Table 2.</a> <a title="AJG_Vol.109_No.5 page 184" href="http://viewer.zmags.com/publication/35da31e7?page=184"> Average incidence of </a> <a title="AJG_Vol.109_No.5 page 185" href="http://viewer.zmags.com/publication/35da31e7?page=185"> 766 West et al. COLON/SMALL BOWEL Table 3.</a> <a title="AJG_Vol.109_No.5 page 186" href="http://viewer.zmags.com/publication/35da31e7?page=186"> Thus, the most logical explanation for the sig</a> <a title="AJG_Vol.109_No.5 page 187" href="http://viewer.zmags.com/publication/35da31e7?page=187"> 768 West et al. COLON/SMALL BOWEL 12. Loga</a> <a title="AJG_Vol.109_No.5 page 188" href="http://viewer.zmags.com/publication/35da31e7?page=188"> nature publishing group </a> <a title="AJG_Vol.109_No.5 page 189" href="http://viewer.zmags.com/publication/35da31e7?page=189"> 770 Letters to the Editor Table 2. Multiv</a> <a title="AJG_Vol.109_No.5 page 190" href="http://viewer.zmags.com/publication/35da31e7?page=190"> Letters to the Editor 771 and twin stud</a> <a title="AJG_Vol.109_No.5 page 191" href="http://viewer.zmags.com/publication/35da31e7?page=191"> 772 Letters to the Editor SNP were avai</a> <a title="AJG_Vol.109_No.5 page 192" href="http://viewer.zmags.com/publication/35da31e7?page=192"> Letters to the Editor 773 Table 1. Compa</a> <a title="AJG_Vol.109_No.5 page 193" href="http://viewer.zmags.com/publication/35da31e7?page=193"> 774 Letters to the Editor Our study i</a> <a title="AJG_Vol.109_No.5 page 194" href="http://viewer.zmags.com/publication/35da31e7?page=194"> Letters to the Editor 775 Table 1. Basel</a> <a title="AJG_Vol.109_No.5 page 195" href="http://viewer.zmags.com/publication/35da31e7?page=195"> 776 Letters to the Editor and N.F.; tre</a> <a title="AJG_Vol.109_No.5 page 196" href="http://viewer.zmags.com/publication/35da31e7?page=196"> 15 13 11 9 7 5 3 No. of physicia</a> <a title="AJG_Vol.109_No.5 page 197" href="http://viewer.zmags.com/publication/35da31e7?page=197"> 778 Letters to the Editor the desire to</a> <a title="AJG_Vol.109_No.5 page 198" href="http://viewer.zmags.com/publication/35da31e7?page=198"> nature publishing group </a> <a title="AJG_Vol.109_No.5 page 199" href="http://viewer.zmags.com/publication/35da31e7?page=199"> 780 ERRATA, CORRIGENDA AND RETRACTIONS </a> <a title="AJG_Vol.109_No.5 page 200" href="http://viewer.zmags.com/publication/35da31e7?page=200"> Errata, Corrigenda and Retractions 781 </a> <a title="AJG_Vol.109_No.5 page 201" href="http://viewer.zmags.com/publication/35da31e7?page=201"> 782 Errata, Corrigenda and Retractions T</a> <a title="AJG_Vol.109_No.5 page 202" href="http://viewer.zmags.com/publication/35da31e7?page=202"> CLASSIFIEDS Gastroenterologist Olympia, WA We ar</a> <a title="AJG_Vol.109_No.5 page 203" href="http://viewer.zmags.com/publication/35da31e7?page=203"> Program Director Gastroenterology The Howard Uni</a> <a title="AJG_Vol.109_No.5 page 204" href="http://viewer.zmags.com/publication/35da31e7?page=204"> </a> <a title="AJG_Vol.109_No.5 page 205" href="http://viewer.zmags.com/publication/35da31e7?page=205"> </a>