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<br /> jpn.ca<br /> An open-access journal<br /> March 2019 Volume 44 Number 2<br /> Age-related deficits in intracortical myelination in young<br /> adults with bipolar disorder type I<br /> Brain grey-matter volume alteration in adult patients<br /> with bipolar disorder under different conditions:<br /> a voxel-based meta-analysis<br /> Publications Mail Agreement no. 41387051<br /> May cause a spike in adrenaline.<br /> Mercedes-Benz Corporate Sales is proud to continue a strong partnership with all<br /> Canadian Medical Association members. Save up to $1,500 in addition to existing<br /> special offers on new Mercedes-Benz. This competitive incentive reflects our<br /> commitment to providing the best ownership experience to CMA members.<br /> See additional incentive details at Mercedes-benz.ca/cma.<br /> © 2019 Mercedes-Benz Canada Inc.<br /> Editors-in-Chief<br /> P. Boksa, PhD<br /> R. Joober, MD, PhD<br /> Editor Emeritus<br /> Y.D. Lapierre, MD<br<a title="JPN; March 2019, Volume 44, Number 2 page 1" href="http://viewer.zmags.com/publication/65651ba3?page=1"> jpn.ca An open-access journal March 2019 </a> <a title="JPN; March 2019, Volume 44, Number 2 page 2" href="http://viewer.zmags.com/publication/65651ba3?page=2"> May cause a spike in adrenaline. Mercedes-Benz C</a> <a title="JPN; March 2019, Volume 44, Number 2 page 3" href="http://viewer.zmags.com/publication/65651ba3?page=3"> Editors-in-Chief P. Boksa, PhD R. Joober, MD, PhD</a> <a title="JPN; March 2019, Volume 44, Number 2 page 4" href="http://viewer.zmags.com/publication/65651ba3?page=4"> Editorial Staff Managing Editor Wendy Carroll wen</a> <a title="JPN; March 2019, Volume 44, Number 2 page 5" href="http://viewer.zmags.com/publication/65651ba3?page=5"> Editorial The views expressed in this editoria</a> <a title="JPN; March 2019, Volume 44, Number 2 page 6" href="http://viewer.zmags.com/publication/65651ba3?page=6"> Abizaid et al. sustained, eventually leading t</a> <a title="JPN; March 2019, Volume 44, Number 2 page 7" href="http://viewer.zmags.com/publication/65651ba3?page=7"> Cannabis: Efficacious for PTSD or simply snake oi</a> <a title="JPN; March 2019, Volume 44, Number 2 page 8" href="http://viewer.zmags.com/publication/65651ba3?page=8"> Abizaid et al. 24. Hill MN, McLaughlin RJ, B</a> <a title="JPN; March 2019, Volume 44, Number 2 page 9" href="http://viewer.zmags.com/publication/65651ba3?page=9"> Research Paper Age-related deficits in intracor</a> <a title="JPN; March 2019, Volume 44, Number 2 page 10" href="http://viewer.zmags.com/publication/65651ba3?page=10"> Sehmbi et al. about white-matter anomalies ste</a> <a title="JPN; March 2019, Volume 44, Number 2 page 11" href="http://viewer.zmags.com/publication/65651ba3?page=11"> Age-related deficits in intracortical myelination</a> <a title="JPN; March 2019, Volume 44, Number 2 page 12" href="http://viewer.zmags.com/publication/65651ba3?page=12"> Sehmbi et al. Table 2: Clinical characteristic</a> <a title="JPN; March 2019, Volume 44, Number 2 page 13" href="http://viewer.zmags.com/publication/65651ba3?page=13"> Age-related deficits in intracortical myelination</a> <a title="JPN; March 2019, Volume 44, Number 2 page 14" href="http://viewer.zmags.com/publication/65651ba3?page=14"> Sehmbi et al. visual and orbitofrontal cortice</a> <a title="JPN; March 2019, Volume 44, Number 2 page 15" href="http://viewer.zmags.com/publication/65651ba3?page=15"> Age-related deficits in intracortical myelination</a> <a title="JPN; March 2019, Volume 44, Number 2 page 16" href="http://viewer.zmags.com/publication/65651ba3?page=16"> Sehmbi et al. primary visual, auditory and som</a> <a title="JPN; March 2019, Volume 44, Number 2 page 17" href="http://viewer.zmags.com/publication/65651ba3?page=17"> Age-related deficits in intracortical myelination</a> <a title="JPN; March 2019, Volume 44, Number 2 page 18" href="http://viewer.zmags.com/publication/65651ba3?page=18"> Sehmbi et al. 41. Hanford LC, Nazarov A, Hal</a> <a title="JPN; March 2019, Volume 44, Number 2 page 19" href="http://viewer.zmags.com/publication/65651ba3?page=19"> Research Paper Brain grey-matter volume alterat</a> <a title="JPN; March 2019, Volume 44, Number 2 page 20" href="http://viewer.zmags.com/publication/65651ba3?page=20"> Wang et al. prefrontal cortex (PFC), the amygd</a> <a title="JPN; March 2019, Volume 44, Number 2 page 21" href="http://viewer.zmags.com/publication/65651ba3?page=21"> Grey-matter volume in adults with BD Voxel-bas</a> <a title="JPN; March 2019, Volume 44, Number 2 page 22" href="http://viewer.zmags.com/publication/65651ba3?page=22"> Wang et al. 17 034 records from electronic data</a> <a title="JPN; March 2019, Volume 44, Number 2 page 23" href="http://viewer.zmags.com/publication/65651ba3?page=23"> Grey-matter volume in adults with BD Bipolar d</a> <a title="JPN; March 2019, Volume 44, Number 2 page 24" href="http://viewer.zmags.com/publication/65651ba3?page=24"> Wang et al. Tables S8 to S12). As indicated by</a> <a title="JPN; March 2019, Volume 44, Number 2 page 25" href="http://viewer.zmags.com/publication/65651ba3?page=25"> Grey-matter volume in adults with BD Meanwhile</a> <a title="JPN; March 2019, Volume 44, Number 2 page 26" href="http://viewer.zmags.com/publication/65651ba3?page=26"> Wang et al. frontoinsular cortex were associat</a> <a title="JPN; March 2019, Volume 44, Number 2 page 27" href="http://viewer.zmags.com/publication/65651ba3?page=27"> Grey-matter volume in adults with BD dynamic) </a> <a title="JPN; March 2019, Volume 44, Number 2 page 28" href="http://viewer.zmags.com/publication/65651ba3?page=28"> Wang et al. intensity of the alterations may b</a> <a title="JPN; March 2019, Volume 44, Number 2 page 29" href="http://viewer.zmags.com/publication/65651ba3?page=29"> Grey-matter volume in adults with BD psychotro</a> <a title="JPN; March 2019, Volume 44, Number 2 page 30" href="http://viewer.zmags.com/publication/65651ba3?page=30"> Wang et al. 6. Baldessarini RJ, Tondo L, Ba</a> <a title="JPN; March 2019, Volume 44, Number 2 page 31" href="http://viewer.zmags.com/publication/65651ba3?page=31"> Grey-matter volume in adults with BD 55. </a> <a title="JPN; March 2019, Volume 44, Number 2 page 32" href="http://viewer.zmags.com/publication/65651ba3?page=32"> Research Paper Cerebral blood flow in striatal </a> <a title="JPN; March 2019, Volume 44, Number 2 page 33" href="http://viewer.zmags.com/publication/65651ba3?page=33"> Association of apathy and rCBF in striatal region</a> <a title="JPN; March 2019, Volume 44, Number 2 page 34" href="http://viewer.zmags.com/publication/65651ba3?page=34"> Schneider et al. echo planar imaging sequence </a> <a title="JPN; March 2019, Volume 44, Number 2 page 35" href="http://viewer.zmags.com/publication/65651ba3?page=35"> Association of apathy and rCBF in striatal region</a> <a title="JPN; March 2019, Volume 44, Number 2 page 36" href="http://viewer.zmags.com/publication/65651ba3?page=36"> Schneider et al. No participants were exclu</a> <a title="JPN; March 2019, Volume 44, Number 2 page 37" href="http://viewer.zmags.com/publication/65651ba3?page=37"> Association of apathy and rCBF in striatal region</a> <a title="JPN; March 2019, Volume 44, Number 2 page 38" href="http://viewer.zmags.com/publication/65651ba3?page=38"> Schneider et al. Table 4: Spearman correlation</a> <a title="JPN; March 2019, Volume 44, Number 2 page 39" href="http://viewer.zmags.com/publication/65651ba3?page=39"> Association of apathy and rCBF in striatal region</a> <a title="JPN; March 2019, Volume 44, Number 2 page 40" href="http://viewer.zmags.com/publication/65651ba3?page=40"> Schneider et al. 35. Lecrubier Y, Weiller E,</a> <a title="JPN; March 2019, Volume 44, Number 2 page 41" href="http://viewer.zmags.com/publication/65651ba3?page=41"> Research Paper GABA levels and TSPO expression </a> <a title="JPN; March 2019, Volume 44, Number 2 page 42" href="http://viewer.zmags.com/publication/65651ba3?page=42"> Da Silva et al. changes underlying schizophren</a> <a title="JPN; March 2019, Volume 44, Number 2 page 43" href="http://viewer.zmags.com/publication/65651ba3?page=43"> GABA and TSPO in people at clinical high risk for</a> <a title="JPN; March 2019, Volume 44, Number 2 page 44" href="http://viewer.zmags.com/publication/65651ba3?page=44"> Da Silva et al. included in our previous cohor</a> <a title="JPN; March 2019, Volume 44, Number 2 page 45" href="http://viewer.zmags.com/publication/65651ba3?page=45"> GABA and TSPO in people at clinical high risk for</a> <a title="JPN; March 2019, Volume 44, Number 2 page 46" href="http://viewer.zmags.com/publication/65651ba3?page=46"> Da Silva et al. meta-analysis of 1H-MRS GABA i</a> <a title="JPN; March 2019, Volume 44, Number 2 page 47" href="http://viewer.zmags.com/publication/65651ba3?page=47"> GABA and TSPO in people at clinical high risk for</a> <a title="JPN; March 2019, Volume 44, Number 2 page 48" href="http://viewer.zmags.com/publication/65651ba3?page=48"> Da Silva et al. Brandt AS, Unschuld P</a> <a title="JPN; March 2019, Volume 44, Number 2 page 49" href="http://viewer.zmags.com/publication/65651ba3?page=49"> GABA and TSPO in people at clinical high risk for</a> <a title="JPN; March 2019, Volume 44, Number 2 page 50" href="http://viewer.zmags.com/publication/65651ba3?page=50"> Research Paper Lateral orbitofrontal dysfunctio</a> <a title="JPN; March 2019, Volume 44, Number 2 page 51" href="http://viewer.zmags.com/publication/65651ba3?page=51"> Orbitofrontal dysfunction in an OCD mouse model </a> <a title="JPN; March 2019, Volume 44, Number 2 page 52" href="http://viewer.zmags.com/publication/65651ba3?page=52"> Lei et al Detailed explanations of these cell-</a> <a title="JPN; March 2019, Volume 44, Number 2 page 53" href="http://viewer.zmags.com/publication/65651ba3?page=53"> Orbitofrontal dysfunction in an OCD mouse model </a> <a title="JPN; March 2019, Volume 44, Number 2 page 54" href="http://viewer.zmags.com/publication/65651ba3?page=54"> Lei et al in Sapap3 KO mice (WT mean ± SEM = 1</a> <a title="JPN; March 2019, Volume 44, Number 2 page 55" href="http://viewer.zmags.com/publication/65651ba3?page=55"> Orbitofrontal dysfunction in an OCD mouse model </a> <a title="JPN; March 2019, Volume 44, Number 2 page 56" href="http://viewer.zmags.com/publication/65651ba3?page=56"> Lei et al we adopted a method that was less se</a> <a title="JPN; March 2019, Volume 44, Number 2 page 57" href="http://viewer.zmags.com/publication/65651ba3?page=57"> Orbitofrontal dysfunction in an OCD mouse model </a> <a title="JPN; March 2019, Volume 44, Number 2 page 58" href="http://viewer.zmags.com/publication/65651ba3?page=58"> Lei et al comorbidities, medication history an</a> <a title="JPN; March 2019, Volume 44, Number 2 page 59" href="http://viewer.zmags.com/publication/65651ba3?page=59"> Orbitofrontal dysfunction in an OCD mouse model </a> <a title="JPN; March 2019, Volume 44, Number 2 page 60" href="http://viewer.zmags.com/publication/65651ba3?page=60"> Lei et al Municipal Technology Foundation for </a> <a title="JPN; March 2019, Volume 44, Number 2 page 61" href="http://viewer.zmags.com/publication/65651ba3?page=61"> Orbitofrontal dysfunction in an OCD mouse model </a> <a title="JPN; March 2019, Volume 44, Number 2 page 62" href="http://viewer.zmags.com/publication/65651ba3?page=62"> Research Paper Spontaneous low-frequency fluct</a> <a title="JPN; March 2019, Volume 44, Number 2 page 63" href="http://viewer.zmags.com/publication/65651ba3?page=63"> Amplitude across frequency bands in major psychia</a> <a title="JPN; March 2019, Volume 44, Number 2 page 64" href="http://viewer.zmags.com/publication/65651ba3?page=64"> Chang et al. Methods Participants This study</a> <a title="JPN; March 2019, Volume 44, Number 2 page 65" href="http://viewer.zmags.com/publication/65651ba3?page=65"> Amplitude across frequency bands in major psychia</a> <a title="JPN; March 2019, Volume 44, Number 2 page 66" href="http://viewer.zmags.com/publication/65651ba3?page=66"> Chang et al. showed a significant negative cor</a> <a title="JPN; March 2019, Volume 44, Number 2 page 67" href="http://viewer.zmags.com/publication/65651ba3?page=67"> Amplitude across frequency bands in major psychia</a> <a title="JPN; March 2019, Volume 44, Number 2 page 68" href="http://viewer.zmags.com/publication/65651ba3?page=68"> Chang et al. markers among different disorders</a> <a title="JPN; March 2019, Volume 44, Number 2 page 69" href="http://viewer.zmags.com/publication/65651ba3?page=69"> Amplitude across frequency bands in major psychia</a> <a title="JPN; March 2019, Volume 44, Number 2 page 70" href="http://viewer.zmags.com/publication/65651ba3?page=70"> Chang et al. significant effects of medication</a> <a title="JPN; March 2019, Volume 44, Number 2 page 71" href="http://viewer.zmags.com/publication/65651ba3?page=71"> Amplitude across frequency bands in major psychia</a> <a title="JPN; March 2019, Volume 44, Number 2 page 72" href="http://viewer.zmags.com/publication/65651ba3?page=72"> Service Information Subscriptions and sales Ann</a> <a title="JPN; March 2019, Volume 44, Number 2 page 73" href="http://viewer.zmags.com/publication/65651ba3?page=73"> Psychopharmacology for the Clinician The infor</a> <a title="JPN; March 2019, Volume 44, Number 2 page 74" href="http://viewer.zmags.com/publication/65651ba3?page=74"> Daskalakis et al. References </a> <a title="JPN; March 2019, Volume 44, Number 2 page 75" href="http://viewer.zmags.com/publication/65651ba3?page=75"> REPRINTS Pub cat ons Ma Agreement no 41387051 U</a> <a title="JPN; March 2019, Volume 44, Number 2 page 76" href="http://viewer.zmags.com/publication/65651ba3?page=76"> Choose for your migraine patients RELPAX is indic</a>