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<br /> SUBSCRIBE<br /> TO RECEIVE<br /> THE LATEST<br /> CATIONS <br /> PUBLI<br /> & UPDATES<br /> FROM A HOST OF FIFTEEN <br /> ETTERS <br /> NEWSL<br /> THERAPEUTIC AREAS<br /> If you are interested in submitting a paper<br /> to EMJ, contact editor@emjreviews.com<br /> Follow us:<br /> www.emjreviews.com<br /> <br /> <br /> HEPATOLOGY<br /> ISSN 2053-4221 May 2014 • emjreviews.com<br /> INSIDE<br /> Review of<br /> ILC 2014<br /> London, UK<br /> <br /> SOVALDI® transforms HCV therapy, allowing<br /> more adult patients the opportunity of cure<br /> In clinical trials<br /> · The first approved nucleotide polymerase inhibitor with pan-genotypic<br /> activity and a high barrier to resistance1<br /> · ≥90% of treatment-naïve adults, across all genotypes are cured with 12 weeks<br /> of SOVALDI + Peg-IFN + RBV (No Peg-IFN r<a title="EMJ Hepatology 2014 page 1" href="http://viewer.zmags.com/publication/6b6592a8?page=1"> SUBSCRIBE TO RECEIVE THE LATEST CATIONS PUBLI</a> <a title="EMJ Hepatology 2014 page 2" href="http://viewer.zmags.com/publication/6b6592a8?page=2"> HEPATOLOGY ISSN 2053-4221 </a> <a title="EMJ Hepatology 2014 page 3" href="http://viewer.zmags.com/publication/6b6592a8?page=3"> </a> <a title="EMJ Hepatology 2014 page 4" href="http://viewer.zmags.com/publication/6b6592a8?page=4"> SOVALDI® transforms HCV therapy, allowing more a</a> <a title="EMJ Hepatology 2014 page 5" href="http://viewer.zmags.com/publication/6b6592a8?page=5"> CONTENTS EDITORIAL BOARD.......................</a> <a title="EMJ Hepatology 2014 page 6" href="http://viewer.zmags.com/publication/6b6592a8?page=6"> HEPATOLOGY USE OF HBSAG QUANTIFICATION TO GUID</a> <a title="EMJ Hepatology 2014 page 7" href="http://viewer.zmags.com/publication/6b6592a8?page=7"> Editorial Board Hepatology Editor-in-Chief: Pr</a> <a title="EMJ Hepatology 2014 page 8" href="http://viewer.zmags.com/publication/6b6592a8?page=8"> Welcome Spring has now sprung, as has our second </a> <a title="EMJ Hepatology 2014 page 9" href="http://viewer.zmags.com/publication/6b6592a8?page=9"> European Medical Journal Hepatology May 2014 P</a> <a title="EMJ Hepatology 2014 page 10" href="http://viewer.zmags.com/publication/6b6592a8?page=10"> Foreword Univ Prof Dr Markus Peck-Radosavljevic </a> <a title="EMJ Hepatology 2014 page 11" href="http://viewer.zmags.com/publication/6b6592a8?page=11"> ILC ANNUAL CONGRESS 2014 EXCEL LONDON EXHIBITION </a> <a title="EMJ Hepatology 2014 page 12" href="http://viewer.zmags.com/publication/6b6592a8?page=12"> Welcome to the European Medical Journal review of</a> <a title="EMJ Hepatology 2014 page 13" href="http://viewer.zmags.com/publication/6b6592a8?page=13"> ILC ANNUAL CONGRESS 2014 EXCEL LONDON EXHIBITION </a> <a title="EMJ Hepatology 2014 page 14" href="http://viewer.zmags.com/publication/6b6592a8?page=14"> The presentation of these new, direct-acting, ant</a> <a title="EMJ Hepatology 2014 page 15" href="http://viewer.zmags.com/publication/6b6592a8?page=15"> ILC ANNUAL CONGRESS 2014 EXCEL LONDON EXHIBITION </a> <a title="EMJ Hepatology 2014 page 16" href="http://viewer.zmags.com/publication/6b6592a8?page=16"> Potential Hepatitis C cure blooms in Chinese foli</a> <a title="EMJ Hepatology 2014 page 17" href="http://viewer.zmags.com/publication/6b6592a8?page=17"> ILC ANNUAL CONGRESS 2014 EXCEL LONDON EXHIBITION </a> <a title="EMJ Hepatology 2014 page 18" href="http://viewer.zmags.com/publication/6b6592a8?page=18"> Confronting hepatitis C: a comprehensive approach</a> <a title="EMJ Hepatology 2014 page 19" href="http://viewer.zmags.com/publication/6b6592a8?page=19"> ILC ANNUAL CONGRESS 2014 EXCEL LONDON EXHIBITION </a> <a title="EMJ Hepatology 2014 page 20" href="http://viewer.zmags.com/publication/6b6592a8?page=20"> Liver disease gets gutsy FAECAL microbiota tr</a> <a title="EMJ Hepatology 2014 page 21" href="http://viewer.zmags.com/publication/6b6592a8?page=21"> ILC ANNUAL CONGRESS 2014 EXCEL LONDON EXHIBITION </a> <a title="EMJ Hepatology 2014 page 22" href="http://viewer.zmags.com/publication/6b6592a8?page=22"> T cell clone wars ADOPTIVE T cell therapy could b</a> <a title="EMJ Hepatology 2014 page 23" href="http://viewer.zmags.com/publication/6b6592a8?page=23"> ILC ANNUAL CONGRESS 2014 EXCEL LONDON EXHIBITION </a> <a title="EMJ Hepatology 2014 page 24" href="http://viewer.zmags.com/publication/6b6592a8?page=24"> Hepatic encephalopathy is not the end of the road</a> <a title="EMJ Hepatology 2014 page 25" href="http://viewer.zmags.com/publication/6b6592a8?page=25"> ILC ANNUAL CONGRESS 2014 EXCEL LONDON EXHIBITION </a> <a title="EMJ Hepatology 2014 page 26" href="http://viewer.zmags.com/publication/6b6592a8?page=26"> Host of therapeutic options to improve HCC patien</a> <a title="EMJ Hepatology 2014 page 27" href="http://viewer.zmags.com/publication/6b6592a8?page=27"> ILC ANNUAL CONGRESS 2014 EXCEL LONDON EXHIBITION </a> <a title="EMJ Hepatology 2014 page 28" href="http://viewer.zmags.com/publication/6b6592a8?page=28"> Fatty livers lead to dangerous hearts CARDIOVASCU</a> <a title="EMJ Hepatology 2014 page 29" href="http://viewer.zmags.com/publication/6b6592a8?page=29"> ILC ANNUAL CONGRESS 2014 EXCEL LONDON EXHIBITION </a> <a title="EMJ Hepatology 2014 page 30" href="http://viewer.zmags.com/publication/6b6592a8?page=30"> Three against one: the attack on hepatitis B EXPE</a> <a title="EMJ Hepatology 2014 page 31" href="http://viewer.zmags.com/publication/6b6592a8?page=31"> ILC ANNUAL CONGRESS 2014 EXCEL LONDON EXHIBITION </a> <a title="EMJ Hepatology 2014 page 32" href="http://viewer.zmags.com/publication/6b6592a8?page=32"> Triangle of action against hepatitis C “These dat</a> <a title="EMJ Hepatology 2014 page 33" href="http://viewer.zmags.com/publication/6b6592a8?page=33"> ILC ANNUAL CONGRESS 2014 EXCEL LONDON EXHIBITION </a> <a title="EMJ Hepatology 2014 page 34" href="http://viewer.zmags.com/publication/6b6592a8?page=34"> Hepatitis C drug shows glittering prowess through</a> <a title="EMJ Hepatology 2014 page 35" href="http://viewer.zmags.com/publication/6b6592a8?page=35"> ILC ANNUAL CONGRESS 2014 EXCEL LONDON EXHIBITION </a> <a title="EMJ Hepatology 2014 page 36" href="http://viewer.zmags.com/publication/6b6592a8?page=36"> Bristol-Myers Squibb: at the Core of HCV Research</a> <a title="EMJ Hepatology 2014 page 37" href="http://viewer.zmags.com/publication/6b6592a8?page=37"> TRANSFORMING HCV MANAGEMENT Summary of Presentati</a> <a title="EMJ Hepatology 2014 page 38" href="http://viewer.zmags.com/publication/6b6592a8?page=38"> development of the second-generation - more </a> <a title="EMJ Hepatology 2014 page 39" href="http://viewer.zmags.com/publication/6b6592a8?page=39"> Initial treatment regimens with IFN </a> <a title="EMJ Hepatology 2014 page 40" href="http://viewer.zmags.com/publication/6b6592a8?page=40"> Perspectives on Therapy for Challenging Pa</a> <a title="EMJ Hepatology 2014 page 41" href="http://viewer.zmags.com/publication/6b6592a8?page=41"> demonstrated up to 98% SVR for GT1 patients in a </a> <a title="EMJ Hepatology 2014 page 42" href="http://viewer.zmags.com/publication/6b6592a8?page=42"> data. AASLD 1–5 November 2013, Washington</a> <a title="EMJ Hepatology 2014 page 43" href="http://viewer.zmags.com/publication/6b6592a8?page=43"> NEWS AT SIX: HEPATITIS C SPECIAL Summary of Pre</a> <a title="EMJ Hepatology 2014 page 44" href="http://viewer.zmags.com/publication/6b6592a8?page=44"> lower against HCV GT 3 and they possess a</a> <a title="EMJ Hepatology 2014 page 45" href="http://viewer.zmags.com/publication/6b6592a8?page=45"> of RBV, must be taken into account.12 Care</a> <a title="EMJ Hepatology 2014 page 46" href="http://viewer.zmags.com/publication/6b6592a8?page=46"> Discrimination and practical difficulties </a> <a title="EMJ Hepatology 2014 page 47" href="http://viewer.zmags.com/publication/6b6592a8?page=47"> transplantation,50 and with current therapies the</a> <a title="EMJ Hepatology 2014 page 48" href="http://viewer.zmags.com/publication/6b6592a8?page=48"> MK-5172/MK-8742 +/- RBV for 12 weeks in HCV genot</a> <a title="EMJ Hepatology 2014 page 49" href="http://viewer.zmags.com/publication/6b6592a8?page=49"> TRANSLATION FROM MICE TO MEN: ARE DOGS A </a> <a title="EMJ Hepatology 2014 page 50" href="http://viewer.zmags.com/publication/6b6592a8?page=50"> Requirements for Animal Models Important requirem</a> <a title="EMJ Hepatology 2014 page 51" href="http://viewer.zmags.com/publication/6b6592a8?page=51"> Table 1: Markers used to investigate mouse, dog o</a> <a title="EMJ Hepatology 2014 page 52" href="http://viewer.zmags.com/publication/6b6592a8?page=52"> Using a plate-and-wait method, colonies of canine</a> <a title="EMJ Hepatology 2014 page 53" href="http://viewer.zmags.com/publication/6b6592a8?page=53"> provides an excellent model for clinical HP</a> <a title="EMJ Hepatology 2014 page 54" href="http://viewer.zmags.com/publication/6b6592a8?page=54"> REFERENCES 1. Riehle KJ et al. New concepts in li</a> <a title="EMJ Hepatology 2014 page 55" href="http://viewer.zmags.com/publication/6b6592a8?page=55"> 48. Kim H et al. Human hepatocellular carcinomas </a> <a title="EMJ Hepatology 2014 page 56" href="http://viewer.zmags.com/publication/6b6592a8?page=56"> OVERLAPPING CLINICAL FEATURES BETWEEN NAFLD </a> <a title="EMJ Hepatology 2014 page 57" href="http://viewer.zmags.com/publication/6b6592a8?page=57"> of specific signs of these diseases that ma</a> <a title="EMJ Hepatology 2014 page 58" href="http://viewer.zmags.com/publication/6b6592a8?page=58"> NAFLD GENETIC BACKGROUND CIRCULATING ADIPOCY</a> <a title="EMJ Hepatology 2014 page 59" href="http://viewer.zmags.com/publication/6b6592a8?page=59"> for the Kruppel-like factor 6 (KLF6), which</a> <a title="EMJ Hepatology 2014 page 60" href="http://viewer.zmags.com/publication/6b6592a8?page=60"> Although the real role of these two adipocytokine</a> <a title="EMJ Hepatology 2014 page 61" href="http://viewer.zmags.com/publication/6b6592a8?page=61"> either for establishing the primary determin</a> <a title="EMJ Hepatology 2014 page 62" href="http://viewer.zmags.com/publication/6b6592a8?page=62"> children with non-alcoholic fatty liver disea</a> <a title="EMJ Hepatology 2014 page 63" href="http://viewer.zmags.com/publication/6b6592a8?page=63"> ADIPOSE TISSUE, METABOLIC SYNDROME, AND NON- ALCO</a> <a title="EMJ Hepatology 2014 page 64" href="http://viewer.zmags.com/publication/6b6592a8?page=64"> the central role of adiposity in the patho</a> <a title="EMJ Hepatology 2014 page 65" href="http://viewer.zmags.com/publication/6b6592a8?page=65"> resistance is accompanied by hyperinsulinaemi</a> <a title="EMJ Hepatology 2014 page 66" href="http://viewer.zmags.com/publication/6b6592a8?page=66"> expanding its adipose tissue, thus these effects </a> <a title="EMJ Hepatology 2014 page 67" href="http://viewer.zmags.com/publication/6b6592a8?page=67"> Some examples include the UCP1 -3826 A>G po</a> <a title="EMJ Hepatology 2014 page 68" href="http://viewer.zmags.com/publication/6b6592a8?page=68"> interventions. Although randomised controll</a> <a title="EMJ Hepatology 2014 page 69" href="http://viewer.zmags.com/publication/6b6592a8?page=69"> the hepatic manifestation of MetS, while in patie</a> <a title="EMJ Hepatology 2014 page 70" href="http://viewer.zmags.com/publication/6b6592a8?page=70"> 2001;96(10):2957–61. 40. Schwimmer JB et al. Prev</a> <a title="EMJ Hepatology 2014 page 71" href="http://viewer.zmags.com/publication/6b6592a8?page=71"> 82. Sookoian S et al. Modest alcohol consum</a> <a title="EMJ Hepatology 2014 page 72" href="http://viewer.zmags.com/publication/6b6592a8?page=72"> COST-EFFECTIVE INTERVENTIONS IN THE CONTROL </a> <a title="EMJ Hepatology 2014 page 73" href="http://viewer.zmags.com/publication/6b6592a8?page=73"> have, as yet, introduced universal HBV vaccinatio</a> <a title="EMJ Hepatology 2014 page 74" href="http://viewer.zmags.com/publication/6b6592a8?page=74"> Table 1: Summary of recently published cost-effec</a> <a title="EMJ Hepatology 2014 page 75" href="http://viewer.zmags.com/publication/6b6592a8?page=75"> Intervention Country/Target Group Summary of </a> <a title="EMJ Hepatology 2014 page 76" href="http://viewer.zmags.com/publication/6b6592a8?page=76"> born abroad but are currently living in Canada. T</a> <a title="EMJ Hepatology 2014 page 77" href="http://viewer.zmags.com/publication/6b6592a8?page=77"> would cost to expand the coverage of existing r</a> <a title="EMJ Hepatology 2014 page 78" href="http://viewer.zmags.com/publication/6b6592a8?page=78"> USE OF HBSAG QUANTIFICATION TO GUIDE HBIG PROPHYL</a> <a title="EMJ Hepatology 2014 page 79" href="http://viewer.zmags.com/publication/6b6592a8?page=79"> from high-dose intravenous (i.v.) HBIG - administ</a> <a title="EMJ Hepatology 2014 page 80" href="http://viewer.zmags.com/publication/6b6592a8?page=80"> complications) or in patients with HCC and </a> <a title="EMJ Hepatology 2014 page 81" href="http://viewer.zmags.com/publication/6b6592a8?page=81"> mIU/mL at day 7. The secondary endpoints were: ev</a> <a title="EMJ Hepatology 2014 page 82" href="http://viewer.zmags.com/publication/6b6592a8?page=82"> HCC was present in 24 (58.5%) and H</a> <a title="EMJ Hepatology 2014 page 83" href="http://viewer.zmags.com/publication/6b6592a8?page=83"> Table 3: Univariate comparison between efficacy p</a> <a title="EMJ Hepatology 2014 page 84" href="http://viewer.zmags.com/publication/6b6592a8?page=84"> DISCUSSION In the setting of LT for HBsAg-relate</a> <a title="EMJ Hepatology 2014 page 85" href="http://viewer.zmags.com/publication/6b6592a8?page=85"> 30,000 IU HBIG (p=0.0002) and underwent further b</a> <a title="EMJ Hepatology 2014 page 86" href="http://viewer.zmags.com/publication/6b6592a8?page=86"> recurrent hepatitis B virus by vaccination after </a> <a title="EMJ Hepatology 2014 page 87" href="http://viewer.zmags.com/publication/6b6592a8?page=87"> LIVER TRANSPLANTATION FOR ALCOHOLIC LIVER </a> <a title="EMJ Hepatology 2014 page 88" href="http://viewer.zmags.com/publication/6b6592a8?page=88"> Recently, increased risk of mortality due to live</a> <a title="EMJ Hepatology 2014 page 89" href="http://viewer.zmags.com/publication/6b6592a8?page=89"> European Association for the Study of the Liver (</a> <a title="EMJ Hepatology 2014 page 90" href="http://viewer.zmags.com/publication/6b6592a8?page=90"> CONCLUSION LT for alcoholic cirrhosis is a matte</a> <a title="EMJ Hepatology 2014 page 91" href="http://viewer.zmags.com/publication/6b6592a8?page=91"> physical complications. London: Royal College </a> <a title="EMJ Hepatology 2014 page 92" href="http://viewer.zmags.com/publication/6b6592a8?page=92"> ACUTE LIVER FAILURE: A DANGEROUS AND </a> <a title="EMJ Hepatology 2014 page 93" href="http://viewer.zmags.com/publication/6b6592a8?page=93"> Acute liver failure (ALF) -Recovery under conse</a> <a title="EMJ Hepatology 2014 page 94" href="http://viewer.zmags.com/publication/6b6592a8?page=94"> A Acute liv</a> <a title="EMJ Hepatology 2014 page 95" href="http://viewer.zmags.com/publication/6b6592a8?page=95"> Table 1: Aetiologies of acute liver failure (ALF)</a> <a title="EMJ Hepatology 2014 page 96" href="http://viewer.zmags.com/publication/6b6592a8?page=96"> of inflammatory cells.31 However, apoptosis itself</a> <a title="EMJ Hepatology 2014 page 97" href="http://viewer.zmags.com/publication/6b6592a8?page=97"> Table 2: Scoring systems in patients with acute l</a> <a title="EMJ Hepatology 2014 page 98" href="http://viewer.zmags.com/publication/6b6592a8?page=98"> of novel markers and diagnostic methods should be</a> <a title="EMJ Hepatology 2014 page 99" href="http://viewer.zmags.com/publication/6b6592a8?page=99"> consumption ingesting paracetamol at the</a> <a title="EMJ Hepatology 2014 page 100" href="http://viewer.zmags.com/publication/6b6592a8?page=100"> ACUTE LIVER FAILURE: PATHOPHYSIOLOGIC BASIS, A</a> <a title="EMJ Hepatology 2014 page 101" href="http://viewer.zmags.com/publication/6b6592a8?page=101"> ALF is a rare condition, with a reported annual i</a> <a title="EMJ Hepatology 2014 page 102" href="http://viewer.zmags.com/publication/6b6592a8?page=102"> blood flow (CBF) and cerebral autoregulation,</a> <a title="EMJ Hepatology 2014 page 103" href="http://viewer.zmags.com/publication/6b6592a8?page=103"> Controversy continues to rage about the use of IC</a> <a title="EMJ Hepatology 2014 page 104" href="http://viewer.zmags.com/publication/6b6592a8?page=104"> Infections and Sepsis in ALF Immune paralysis, </a> <a title="EMJ Hepatology 2014 page 105" href="http://viewer.zmags.com/publication/6b6592a8?page=105"> such as ventilator associated pneumonias, acute l</a> <a title="EMJ Hepatology 2014 page 106" href="http://viewer.zmags.com/publication/6b6592a8?page=106"> subacute ALF), are occasionally used. Although th</a> <a title="EMJ Hepatology 2014 page 107" href="http://viewer.zmags.com/publication/6b6592a8?page=107"> muscles as phenylacetylglutamine (PAGN), and </a> <a title="EMJ Hepatology 2014 page 108" href="http://viewer.zmags.com/publication/6b6592a8?page=108"> hyperammonemia to cerebral edema. Metab Brain </a> <a title="EMJ Hepatology 2014 page 109" href="http://viewer.zmags.com/publication/6b6592a8?page=109"> WHAT’S NEW: INTERVIEW Sovaldi®: winning the battl</a> <a title="EMJ Hepatology 2014 page 110" href="http://viewer.zmags.com/publication/6b6592a8?page=110"> HEPATOLOGY molecule is being targeting to be cov</a> <a title="EMJ Hepatology 2014 page 111" href="http://viewer.zmags.com/publication/6b6592a8?page=111"> WHAT’S NEW New liver </a> <a title="EMJ Hepatology 2014 page 112" href="http://viewer.zmags.com/publication/6b6592a8?page=112"> HEPATOLOGY Transforming skin cells into liver cel</a> <a title="EMJ Hepatology 2014 page 113" href="http://viewer.zmags.com/publication/6b6592a8?page=113"> WHAT’S NEW Mysterious mutation causing liver canc</a> <a title="EMJ Hepatology 2014 page 114" href="http://viewer.zmags.com/publication/6b6592a8?page=114"> HEPATOLOGY New budding treatment for hepatitis B </a> <a title="EMJ Hepatology 2014 page 115" href="http://viewer.zmags.com/publication/6b6592a8?page=115"> WHAT’S NEW Topiramate, curbing alcohol consumptio</a> <a title="EMJ Hepatology 2014 page 116" href="http://viewer.zmags.com/publication/6b6592a8?page=116"> HEPATOLOGY From stem cells to pure liver and panc</a> <a title="EMJ Hepatology 2014 page 117" href="http://viewer.zmags.com/publication/6b6592a8?page=117"> WHAT’S NEW Preventing the lethal consequences of </a> <a title="EMJ Hepatology 2014 page 118" href="http://viewer.zmags.com/publication/6b6592a8?page=118"> HEPATOLOGY Zebrafish model used to detect new canc</a> <a title="EMJ Hepatology 2014 page 119" href="http://viewer.zmags.com/publication/6b6592a8?page=119"> WHAT’S NEW Last-minute holiday deals may harm liv</a> <a title="EMJ Hepatology 2014 page 120" href="http://viewer.zmags.com/publication/6b6592a8?page=120"> HEPATOLOGY Omega-3 fighting fatty liver disease OM</a> <a title="EMJ Hepatology 2014 page 121" href="http://viewer.zmags.com/publication/6b6592a8?page=121"> WHAT’S NEW Stop blaming fructose for NAFLD FRUCTO</a> <a title="EMJ Hepatology 2014 page 122" href="http://viewer.zmags.com/publication/6b6592a8?page=122"> HEPATOLOGY Mood-stabilising drug to treat ATD </a> <a title="EMJ Hepatology 2014 page 123" href="http://viewer.zmags.com/publication/6b6592a8?page=123"> WHAT’S NEW Breakthrough potential hepatitis C vac</a> <a title="EMJ Hepatology 2014 page 124" href="http://viewer.zmags.com/publication/6b6592a8?page=124"> HEPATOLOGY Saliva protein reducing mortality in A</a> <a title="EMJ Hepatology 2014 page 125" href="http://viewer.zmags.com/publication/6b6592a8?page=125"> WHAT’S NEW GPB shows promise for cirrhosis patien</a> <a title="EMJ Hepatology 2014 page 126" href="http://viewer.zmags.com/publication/6b6592a8?page=126"> A HISTORY OF INNOVATION. A COMMITMENT TO CHRONIC </a> <a title="EMJ Hepatology 2014 page 127" href="http://viewer.zmags.com/publication/6b6592a8?page=127"> Featured Suppliers Hepatology Almirall is an in</a> <a title="EMJ Hepatology 2014 page 128" href="http://viewer.zmags.com/publication/6b6592a8?page=128"> Bristol-Myers Squibb: at the Core of HCV Research</a> <a title="EMJ Hepatology 2014 page 129" href="http://viewer.zmags.com/publication/6b6592a8?page=129"> Buyer’s Guide & Societies Exhibitors • ABBOTT </a> <a title="EMJ Hepatology 2014 page 130" href="http://viewer.zmags.com/publication/6b6592a8?page=130"> Hepatology Partner Associations • AASLD - AMER</a> <a title="EMJ Hepatology 2014 page 131" href="http://viewer.zmags.com/publication/6b6592a8?page=131"> UPCOMING EVENTS International Liver Transplantat</a> <a title="EMJ Hepatology 2014 page 132" href="http://viewer.zmags.com/publication/6b6592a8?page=132"> HEPATOLOGY European Association for the Study of</a> <a title="EMJ Hepatology 2014 page 133" href="http://viewer.zmags.com/publication/6b6592a8?page=133"> From a host of fifteen therapeutic areas, EUROPEAN</a>