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<br /> UROLOGY<br /> ISSN 2053-4213 May 2014 • emjreviews.com<br /> INSIDE<br /> Review of<br /> EAU 2014<br /> Stockholm, Sweden<br /> CONTENTS<br /> EDITORIAL BOARD................................................................................................................................. 4<br /> CONGRESS REVIEW............................................................................................................................... 8<br /> • Review of the European Association of Urology Congress held in Stockholm,<br /> Sweden, 11th-15th April 2014<br /> SYMPOSIUM REVIEWS<br /> • The Many Faces Of mCRPC: Assessing Patient Profiles And Tailoring Treatment In<br /> A Changing Therapeutic Landscape.............................................................................................. 28<br /> • Innovative Approaches In Urologi<a title="EMJ Urology 2014 page 1" href="http://viewer.zmags.com/publication/6b7991ac?page=1"> UROLOGY ISSN 2053-4213 </a> <a title="EMJ Urology 2014 page 2" href="http://viewer.zmags.com/publication/6b7991ac?page=2"> CONTENTS EDITORIAL BOARD.......................</a> <a title="EMJ Urology 2014 page 3" href="http://viewer.zmags.com/publication/6b7991ac?page=3"> UROLOGY ATHEROSCLEROSIS AND INFLAMMATORY STATU</a> <a title="EMJ Urology 2014 page 4" href="http://viewer.zmags.com/publication/6b7991ac?page=4"> Editorial Board Urology Editor-in-Chief: Dr Al</a> <a title="EMJ Urology 2014 page 5" href="http://viewer.zmags.com/publication/6b7991ac?page=5"> Welcome Welcome to the second edition of the Euro</a> <a title="EMJ Urology 2014 page 6" href="http://viewer.zmags.com/publication/6b7991ac?page=6"> European Medical Journal Urology May 2014 Publ</a> <a title="EMJ Urology 2014 page 7" href="http://viewer.zmags.com/publication/6b7991ac?page=7"> Foreword Dr Ali Serdar Gözen </a> <a title="EMJ Urology 2014 page 8" href="http://viewer.zmags.com/publication/6b7991ac?page=8"> EAU ANNUAL CONGRESS 2014 STOCKHOLMSMÄSSAN, STOCKH</a> <a title="EMJ Urology 2014 page 9" href="http://viewer.zmags.com/publication/6b7991ac?page=9"> Welcome to the European Medical Journal review of</a> <a title="EMJ Urology 2014 page 10" href="http://viewer.zmags.com/publication/6b7991ac?page=10"> EAU ANNUAL CONGRESS 2014 STOCKHOLMSMÄSSAN, STOCKH</a> <a title="EMJ Urology 2014 page 11" href="http://viewer.zmags.com/publication/6b7991ac?page=11"> At the opening ceremony, the EAU Congress r</a> <a title="EMJ Urology 2014 page 12" href="http://viewer.zmags.com/publication/6b7991ac?page=12"> EAU ANNUAL CONGRESS 2014 STOCKHOLMSMÄSSAN, STOCKH</a> <a title="EMJ Urology 2014 page 13" href="http://viewer.zmags.com/publication/6b7991ac?page=13"> Pelvic floor muscle exercises: the solution to pre</a> <a title="EMJ Urology 2014 page 14" href="http://viewer.zmags.com/publication/6b7991ac?page=14"> EAU ANNUAL CONGRESS 2014 STOCKHOLMSMÄSSAN, STOCKH</a> <a title="EMJ Urology 2014 page 15" href="http://viewer.zmags.com/publication/6b7991ac?page=15"> A giant leap forward for robotic surgery A FRONTI</a> <a title="EMJ Urology 2014 page 16" href="http://viewer.zmags.com/publication/6b7991ac?page=16"> EAU ANNUAL CONGRESS 2014 STOCKHOLMSMÄSSAN, STOCKH</a> <a title="EMJ Urology 2014 page 17" href="http://viewer.zmags.com/publication/6b7991ac?page=17"> Nightmare of nocturia hits patient activity level</a> <a title="EMJ Urology 2014 page 18" href="http://viewer.zmags.com/publication/6b7991ac?page=18"> EAU ANNUAL CONGRESS 2014 STOCKHOLMSMÄSSAN, STOCKH</a> <a title="EMJ Urology 2014 page 19" href="http://viewer.zmags.com/publication/6b7991ac?page=19"> Golden rubric of renal transplantation ruling out</a> <a title="EMJ Urology 2014 page 20" href="http://viewer.zmags.com/publication/6b7991ac?page=20"> EAU ANNUAL CONGRESS 2014 STOCKHOLMSMÄSSAN, STOCKH</a> <a title="EMJ Urology 2014 page 21" href="http://viewer.zmags.com/publication/6b7991ac?page=21"> Non-attendance for prostate cancer monitoring cas</a> <a title="EMJ Urology 2014 page 22" href="http://viewer.zmags.com/publication/6b7991ac?page=22"> EAU ANNUAL CONGRESS 2014 STOCKHOLMSMÄSSAN, STOCKH</a> <a title="EMJ Urology 2014 page 23" href="http://viewer.zmags.com/publication/6b7991ac?page=23"> Urological tumour treatment looks to transplant t</a> <a title="EMJ Urology 2014 page 24" href="http://viewer.zmags.com/publication/6b7991ac?page=24"> EAU ANNUAL CONGRESS 2014 STOCKHOLMSMÄSSAN, STOCKH</a> <a title="EMJ Urology 2014 page 25" href="http://viewer.zmags.com/publication/6b7991ac?page=25"> Robotic technology in paediatric urology: who is </a> <a title="EMJ Urology 2014 page 26" href="http://viewer.zmags.com/publication/6b7991ac?page=26"> EAU ANNUAL CONGRESS 2014 STOCKHOLMSMÄSSAN, STOCKH</a> <a title="EMJ Urology 2014 page 27" href="http://viewer.zmags.com/publication/6b7991ac?page=27"> Three good reasons to use an antagonist in adv</a> <a title="EMJ Urology 2014 page 28" href="http://viewer.zmags.com/publication/6b7991ac?page=28"> THE MANY FACES OF MCRPC: ASSESSING PATIENT </a> <a title="EMJ Urology 2014 page 29" href="http://viewer.zmags.com/publication/6b7991ac?page=29"> demonstrated improved long-term survival when giv</a> <a title="EMJ Urology 2014 page 30" href="http://viewer.zmags.com/publication/6b7991ac?page=30"> Examining Biomarkers in the Management </a> <a title="EMJ Urology 2014 page 31" href="http://viewer.zmags.com/publication/6b7991ac?page=31"> Professor Loidl continued with the presentat</a> <a title="EMJ Urology 2014 page 32" href="http://viewer.zmags.com/publication/6b7991ac?page=32"> REFERENCES 1. Saad F, Hotte SJ. Guidelines for t</a> <a title="EMJ Urology 2014 page 33" href="http://viewer.zmags.com/publication/6b7991ac?page=33"> INNOVATIVE APPROACHES IN UROLOGICAL CANCERS Summa</a> <a title="EMJ Urology 2014 page 34" href="http://viewer.zmags.com/publication/6b7991ac?page=34"> </a> <a title="EMJ Urology 2014 page 35" href="http://viewer.zmags.com/publication/6b7991ac?page=35"> other delicate surface structures to identify are</a> <a title="EMJ Urology 2014 page 36" href="http://viewer.zmags.com/publication/6b7991ac?page=36"> 100Radiographic Progression-free Survival 80 H</a> <a title="EMJ Urology 2014 page 37" href="http://viewer.zmags.com/publication/6b7991ac?page=37"> cell-intrinsic phenomena. The biological capabili</a> <a title="EMJ Urology 2014 page 38" href="http://viewer.zmags.com/publication/6b7991ac?page=38"> the tumour, as the cytokines it releases lead to </a> <a title="EMJ Urology 2014 page 39" href="http://viewer.zmags.com/publication/6b7991ac?page=39"> Concluding Remarks Professor Hendrik Van Poppel </a> <a title="EMJ Urology 2014 page 40" href="http://viewer.zmags.com/publication/6b7991ac?page=40"> Urol. 2011;185:787–94. 31. Fizazi K et al. Abirat</a> <a title="EMJ Urology 2014 page 41" href="http://viewer.zmags.com/publication/6b7991ac?page=41"> GLYCOSAMINOGLYCAN-REPLENISHMENT THERAPY: RATIO</a> <a title="EMJ Urology 2014 page 42" href="http://viewer.zmags.com/publication/6b7991ac?page=42"> as the cellular membrane at the apical surface is</a> <a title="EMJ Urology 2014 page 43" href="http://viewer.zmags.com/publication/6b7991ac?page=43"> A damaged GAG layer (Figure 1) is increasingly pe</a> <a title="EMJ Urology 2014 page 44" href="http://viewer.zmags.com/publication/6b7991ac?page=44"> Table 1: Retrospective case-control study of effe</a> <a title="EMJ Urology 2014 page 45" href="http://viewer.zmags.com/publication/6b7991ac?page=45"> GAG replenishment, as well as a decrease in UTI r</a> <a title="EMJ Urology 2014 page 46" href="http://viewer.zmags.com/publication/6b7991ac?page=46"> useful, especially in patients who are refractory</a> <a title="EMJ Urology 2014 page 47" href="http://viewer.zmags.com/publication/6b7991ac?page=47"> and function of chondroitin sulfate and other sul</a> <a title="EMJ Urology 2014 page 48" href="http://viewer.zmags.com/publication/6b7991ac?page=48"> PROSTATE CANCER: A STATE OF THE HEART Summary of</a> <a title="EMJ Urology 2014 page 49" href="http://viewer.zmags.com/publication/6b7991ac?page=49"> hormones, also known as the back door pathway, al</a> <a title="EMJ Urology 2014 page 50" href="http://viewer.zmags.com/publication/6b7991ac?page=50"> men treated with CAB (LHRH agonist + anti-</a> <a title="EMJ Urology 2014 page 51" href="http://viewer.zmags.com/publication/6b7991ac?page=51"> cancer. A cohort study of 30,721 patients </a> <a title="EMJ Urology 2014 page 52" href="http://viewer.zmags.com/publication/6b7991ac?page=52"> As a cardiologist, Prof Nilsson concluded t</a> <a title="EMJ Urology 2014 page 53" href="http://viewer.zmags.com/publication/6b7991ac?page=53"> factors and the decline in mortality from cardiov</a> <a title="EMJ Urology 2014 page 54" href="http://viewer.zmags.com/publication/6b7991ac?page=54"> HEALTH AND WELLBEING IMPACT AND TREATMENT OF </a> <a title="EMJ Urology 2014 page 55" href="http://viewer.zmags.com/publication/6b7991ac?page=55"> population studies. Using the clinically rel</a> <a title="EMJ Urology 2014 page 56" href="http://viewer.zmags.com/publication/6b7991ac?page=56"> impacting on QoL. The Boston Area Community Healt</a> <a title="EMJ Urology 2014 page 57" href="http://viewer.zmags.com/publication/6b7991ac?page=57"> LUTS/BPH Pharmacotherapy Alpha-blockers are the m</a> <a title="EMJ Urology 2014 page 58" href="http://viewer.zmags.com/publication/6b7991ac?page=58"> REFERENCES 1. Abrams P et al. The standardisatio</a> <a title="EMJ Urology 2014 page 59" href="http://viewer.zmags.com/publication/6b7991ac?page=59"> 48. Cardozo L et al. Randomized, double- blind pl</a> <a title="EMJ Urology 2014 page 60" href="http://viewer.zmags.com/publication/6b7991ac?page=60"> INCREASED HYALURONAN ACID BINDING ABILITY OF S</a> <a title="EMJ Urology 2014 page 61" href="http://viewer.zmags.com/publication/6b7991ac?page=61"> autoimmunity. In about 50% of all sub-/infertile </a> <a title="EMJ Urology 2014 page 62" href="http://viewer.zmags.com/publication/6b7991ac?page=62"> Primary Outcome Assessment: SHBA Values The prese</a> <a title="EMJ Urology 2014 page 63" href="http://viewer.zmags.com/publication/6b7991ac?page=63"> higher than the 2.1% decrease observed in </a> <a title="EMJ Urology 2014 page 64" href="http://viewer.zmags.com/publication/6b7991ac?page=64"> of sperm DNA integrity. An increase of hyaluronan</a> <a title="EMJ Urology 2014 page 65" href="http://viewer.zmags.com/publication/6b7991ac?page=65"> 21. Suleiman SA et al. Lipid peroxidation and hum</a> <a title="EMJ Urology 2014 page 66" href="http://viewer.zmags.com/publication/6b7991ac?page=66"> PREVENTION OF CATHETER-ASSOCIATED URINARY TRACT</a> <a title="EMJ Urology 2014 page 67" href="http://viewer.zmags.com/publication/6b7991ac?page=67"> Significant bacteriuria or positive urine culture </a> <a title="EMJ Urology 2014 page 68" href="http://viewer.zmags.com/publication/6b7991ac?page=68"> dose of chemoprophylaxis; 8) duration of post- ca</a> <a title="EMJ Urology 2014 page 69" href="http://viewer.zmags.com/publication/6b7991ac?page=69"> to surgery, and ending anywhere from catheter rem</a> <a title="EMJ Urology 2014 page 70" href="http://viewer.zmags.com/publication/6b7991ac?page=70"> Table 1: Rating of randomised controlled trials </a> <a title="EMJ Urology 2014 page 71" href="http://viewer.zmags.com/publication/6b7991ac?page=71"> In the only study comparing methenamine with an a</a> <a title="EMJ Urology 2014 page 72" href="http://viewer.zmags.com/publication/6b7991ac?page=72"> that although prophylaxis is not without si</a> <a title="EMJ Urology 2014 page 73" href="http://viewer.zmags.com/publication/6b7991ac?page=73"> 6. Pickard R et al. Types of urethral catheter fo</a> <a title="EMJ Urology 2014 page 74" href="http://viewer.zmags.com/publication/6b7991ac?page=74"> ATHEROSCLEROSIS AND INFLAMMATORY STATUS IN CHRO</a> <a title="EMJ Urology 2014 page 75" href="http://viewer.zmags.com/publication/6b7991ac?page=75"> Besides traditional risk factors incl</a> <a title="EMJ Urology 2014 page 76" href="http://viewer.zmags.com/publication/6b7991ac?page=76"> CV outcomes and why these anticipated e</a> <a title="EMJ Urology 2014 page 77" href="http://viewer.zmags.com/publication/6b7991ac?page=77"> A.51,52 ABPM may be more informative regarding th</a> <a title="EMJ Urology 2014 page 78" href="http://viewer.zmags.com/publication/6b7991ac?page=78"> Vessels In health </a> <a title="EMJ Urology 2014 page 79" href="http://viewer.zmags.com/publication/6b7991ac?page=79"> calcification (MIAC) syndrome. MIAC syndrome has b</a> <a title="EMJ Urology 2014 page 80" href="http://viewer.zmags.com/publication/6b7991ac?page=80"> 4.3%, 5.2%, and 11.1%, respectively. The principa</a> <a title="EMJ Urology 2014 page 81" href="http://viewer.zmags.com/publication/6b7991ac?page=81"> American Heart Association Task Force on Practi</a> <a title="EMJ Urology 2014 page 82" href="http://viewer.zmags.com/publication/6b7991ac?page=82"> of RAW264.7 cells in the absence of Fn14/Tw</a> <a title="EMJ Urology 2014 page 83" href="http://viewer.zmags.com/publication/6b7991ac?page=83"> RECENT ADVANCES IN PERCUTANEOUS NEPHROLITHOTOMY *</a> <a title="EMJ Urology 2014 page 84" href="http://viewer.zmags.com/publication/6b7991ac?page=84"> IMAGING Computed tomography (CT) is </a> <a title="EMJ Urology 2014 page 85" href="http://viewer.zmags.com/publication/6b7991ac?page=85"> The ROC AUC for predictions based on this </a> <a title="EMJ Urology 2014 page 86" href="http://viewer.zmags.com/publication/6b7991ac?page=86"> Nine patients were stone-free at the end o</a> <a title="EMJ Urology 2014 page 87" href="http://viewer.zmags.com/publication/6b7991ac?page=87"> The use of augmented reality </a> <a title="EMJ Urology 2014 page 88" href="http://viewer.zmags.com/publication/6b7991ac?page=88"> needed. The most important advancement in </a> <a title="EMJ Urology 2014 page 89" href="http://viewer.zmags.com/publication/6b7991ac?page=89"> prostate cancer: demonstration of an adaptive</a> <a title="EMJ Urology 2014 page 90" href="http://viewer.zmags.com/publication/6b7991ac?page=90"> A LITERATURE-BASED ANALYSIS OF THE LE</a> <a title="EMJ Urology 2014 page 91" href="http://viewer.zmags.com/publication/6b7991ac?page=91"> Coinciding with a similar rise in the rate of RAR</a> <a title="EMJ Urology 2014 page 92" href="http://viewer.zmags.com/publication/6b7991ac?page=92"> Outcome variable (e.g. PSM) Plateau area of curv</a> <a title="EMJ Urology 2014 page 93" href="http://viewer.zmags.com/publication/6b7991ac?page=93"> Table 1: Studies evaluating the perioperative lea</a> <a title="EMJ Urology 2014 page 94" href="http://viewer.zmags.com/publication/6b7991ac?page=94"> The oncologic LC consists of two variables: the P</a> <a title="EMJ Urology 2014 page 95" href="http://viewer.zmags.com/publication/6b7991ac?page=95"> authors were unable to demonstrate a plateauing o</a> <a title="EMJ Urology 2014 page 96" href="http://viewer.zmags.com/publication/6b7991ac?page=96"> measure it and can we influence it? BJU Int. 2004;</a> <a title="EMJ Urology 2014 page 97" href="http://viewer.zmags.com/publication/6b7991ac?page=97"> LAPAROSCOPIC RADICAL PROSTATECTOMY IN THE </a> <a title="EMJ Urology 2014 page 98" href="http://viewer.zmags.com/publication/6b7991ac?page=98"> Table 1: Perioperative outcomes of laparoscopic r</a> <a title="EMJ Urology 2014 page 99" href="http://viewer.zmags.com/publication/6b7991ac?page=99"> compared with open prostatectomy. A recent a</a> <a title="EMJ Urology 2014 page 100" href="http://viewer.zmags.com/publication/6b7991ac?page=100"> Table 2: Oncological outcomes of laparoscopic rad</a> <a title="EMJ Urology 2014 page 101" href="http://viewer.zmags.com/publication/6b7991ac?page=101"> 25 (27%) met the pentafecta. The majority (80%) o</a> <a title="EMJ Urology 2014 page 102" href="http://viewer.zmags.com/publication/6b7991ac?page=102"> is expected to be reduced and its worldwid</a> <a title="EMJ Urology 2014 page 103" href="http://viewer.zmags.com/publication/6b7991ac?page=103"> extraperitoneal radical prostatectomy: evolut</a> <a title="EMJ Urology 2014 page 104" href="http://viewer.zmags.com/publication/6b7991ac?page=104"> ROBOTIC RADICAL CYSTECTOMY FOR BLADDER </a> <a title="EMJ Urology 2014 page 105" href="http://viewer.zmags.com/publication/6b7991ac?page=105"> (1A) </a> <a title="EMJ Urology 2014 page 106" href="http://viewer.zmags.com/publication/6b7991ac?page=106"> Consortium (IRCC) series, a PSM rate </a> <a title="EMJ Urology 2014 page 107" href="http://viewer.zmags.com/publication/6b7991ac?page=107"> the edge of the endopelvic fascia over the</a> <a title="EMJ Urology 2014 page 108" href="http://viewer.zmags.com/publication/6b7991ac?page=108"> surgery, following the insertion of ureteral sten</a> <a title="EMJ Urology 2014 page 109" href="http://viewer.zmags.com/publication/6b7991ac?page=109"> hospital stay, and time to resumption of regular </a> <a title="EMJ Urology 2014 page 110" href="http://viewer.zmags.com/publication/6b7991ac?page=110"> cancer’. Canda AE (eds), Bladder Cancer: From Bas</a> <a title="EMJ Urology 2014 page 111" href="http://viewer.zmags.com/publication/6b7991ac?page=111"> NEOADJUVANT CHEMOTHERAPY IN MUSCLE-INVASIVE </a> <a title="EMJ Urology 2014 page 112" href="http://viewer.zmags.com/publication/6b7991ac?page=112"> However, until today, optimal timing of the thera</a> <a title="EMJ Urology 2014 page 113" href="http://viewer.zmags.com/publication/6b7991ac?page=113"> Cystectomy Trial I, and the second, N</a> <a title="EMJ Urology 2014 page 114" href="http://viewer.zmags.com/publication/6b7991ac?page=114"> WHO SHOULD RECEIVE NAC? As discussed above, MIBC</a> <a title="EMJ Urology 2014 page 115" href="http://viewer.zmags.com/publication/6b7991ac?page=115"> However, the study was retrospective in nature, a</a> <a title="EMJ Urology 2014 page 116" href="http://viewer.zmags.com/publication/6b7991ac?page=116"> been previously used in metastatic melanoma and </a> <a title="EMJ Urology 2014 page 117" href="http://viewer.zmags.com/publication/6b7991ac?page=117"> cancer results in worse pathological stage. J</a> <a title="EMJ Urology 2014 page 118" href="http://viewer.zmags.com/publication/6b7991ac?page=118"> WHAT’S NEW Personalising said Mr Roman Gulati, le</a> <a title="EMJ Urology 2014 page 119" href="http://viewer.zmags.com/publication/6b7991ac?page=119"> UROLOGY One drug to cure two cancers TRASTUZUMAB </a> <a title="EMJ Urology 2014 page 120" href="http://viewer.zmags.com/publication/6b7991ac?page=120"> WHAT’S NEW Dance incontinence away DANCING is not</a> <a title="EMJ Urology 2014 page 121" href="http://viewer.zmags.com/publication/6b7991ac?page=121"> UROLOGY Increased testosterone leading to increas</a> <a title="EMJ Urology 2014 page 122" href="http://viewer.zmags.com/publication/6b7991ac?page=122"> WHAT’S NEW Prostate cancer drugs not preventing r</a> <a title="EMJ Urology 2014 page 123" href="http://viewer.zmags.com/publication/6b7991ac?page=123"> UROLOGY ADT: changing men, both mentally and emot</a> <a title="EMJ Urology 2014 page 124" href="http://viewer.zmags.com/publication/6b7991ac?page=124"> WHAT’S NEW Botox: combatting wrinkles and incont</a> <a title="EMJ Urology 2014 page 125" href="http://viewer.zmags.com/publication/6b7991ac?page=125"> Would you like to write for the EMJ blog? 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