If you are visually impaired or blind, you can visit the PDF version by Pressing CONTROL + ALT + 4
<br /> GASTROENTEROLOGY<br /> ISSN 2054-6203 December 2014 • emjreviews.com<br /> INSIDE<br /> Review of<br /> UEG 2014<br /> Vienna, Austria<br /> CONTENTS<br /> EDITORIAL BOARD................................................................................................................................. 5<br /> CONGRESS REVIEW............................................................................................................................... 10<br /> • Review of the United European Gastroenterology Week Congress, held in Vienna,<br /> Austria, 18th-22nd September 2014<br /> HIGHLIGHTS FROM THE UEG WEEK CONGRESS 2014: NEW EVIDENCE AND NOVEL<br /> THERAPIES FOR IRRITABLE BOWEL SYNDROME.................................................................................. 36<br /> • Caroline Charles and Enrico Stefano Corazziari<br /> A PROKINETIC AGENT WITH A D<a title="EMJ Gastroenterology 2014 page 1" href="http://viewer.zmags.com/publication/6efed8a9?page=1"> GASTROENTEROLOGY ISSN 2054-6203 </a> <a title="EMJ Gastroenterology 2014 page 2" href="http://viewer.zmags.com/publication/6efed8a9?page=2"> CONTENTS EDITORIAL BOARD.......................</a> <a title="EMJ Gastroenterology 2014 page 3" href="http://viewer.zmags.com/publication/6efed8a9?page=3"> GASTROENTEROLOGY THE MANAGEMENT OF ACUTE UPPER</a> <a title="EMJ Gastroenterology 2014 page 4" href="http://viewer.zmags.com/publication/6efed8a9?page=4"> Your continuous access to congress recordings </a> <a title="EMJ Gastroenterology 2014 page 5" href="http://viewer.zmags.com/publication/6efed8a9?page=5"> Editorial Board Gastroenterology Editor-in-Chi</a> <a title="EMJ Gastroenterology 2014 page 6" href="http://viewer.zmags.com/publication/6efed8a9?page=6"> Introducing Entyvio: the first and only gut-select</a> <a title="EMJ Gastroenterology 2014 page 7" href="http://viewer.zmags.com/publication/6efed8a9?page=7"> Welcome Innovation, best-practice, improving pati</a> <a title="EMJ Gastroenterology 2014 page 8" href="http://viewer.zmags.com/publication/6efed8a9?page=8"> SUBSCRIBE TO THE EMJ NEWSLETTER www.news.emjre</a> <a title="EMJ Gastroenterology 2014 page 9" href="http://viewer.zmags.com/publication/6efed8a9?page=9"> Foreword Prof Marco Bruno Professor and Head of t</a> <a title="EMJ Gastroenterology 2014 page 10" href="http://viewer.zmags.com/publication/6efed8a9?page=10"> UEG WEEK ANNUAL CONGRESS 2014 AUSTRIA CENTER VIEN</a> <a title="EMJ Gastroenterology 2014 page 11" href="http://viewer.zmags.com/publication/6efed8a9?page=11"> Welcome to the European Medical Journal review of</a> <a title="EMJ Gastroenterology 2014 page 12" href="http://viewer.zmags.com/publication/6efed8a9?page=12"> UEG WEEK ANNUAL CONGRESS 2014 AUSTRIA CENTER VIEN</a> <a title="EMJ Gastroenterology 2014 page 13" href="http://viewer.zmags.com/publication/6efed8a9?page=13"> ageing population and declining economy, the curr</a> <a title="EMJ Gastroenterology 2014 page 14" href="http://viewer.zmags.com/publication/6efed8a9?page=14"> UEG WEEK ANNUAL CONGRESS 2014 AUSTRIA CENTER VIEN</a> <a title="EMJ Gastroenterology 2014 page 15" href="http://viewer.zmags.com/publication/6efed8a9?page=15"> Warning lights flash for GI control in Europe </a> <a title="EMJ Gastroenterology 2014 page 16" href="http://viewer.zmags.com/publication/6efed8a9?page=16"> UEG WEEK ANNUAL CONGRESS 2014 AUSTRIA CENTER VIEN</a> <a title="EMJ Gastroenterology 2014 page 17" href="http://viewer.zmags.com/publication/6efed8a9?page=17"> Digging was revealed </a> <a title="EMJ Gastroenterology 2014 page 18" href="http://viewer.zmags.com/publication/6efed8a9?page=18"> UEG WEEK ANNUAL CONGRESS 2014 AUSTRIA CENTER VIEN</a> <a title="EMJ Gastroenterology 2014 page 19" href="http://viewer.zmags.com/publication/6efed8a9?page=19"> Pills providing the solution for hepatitis C reli</a> <a title="EMJ Gastroenterology 2014 page 20" href="http://viewer.zmags.com/publication/6efed8a9?page=20"> UEG WEEK ANNUAL CONGRESS 2014 AUSTRIA CENTER VIEN</a> <a title="EMJ Gastroenterology 2014 page 21" href="http://viewer.zmags.com/publication/6efed8a9?page=21"> Psychological blow of IBD highlighted in the youn</a> <a title="EMJ Gastroenterology 2014 page 22" href="http://viewer.zmags.com/publication/6efed8a9?page=22"> UEG WEEK ANNUAL CONGRESS 2014 AUSTRIA CENTER VIEN</a> <a title="EMJ Gastroenterology 2014 page 23" href="http://viewer.zmags.com/publication/6efed8a9?page=23"> Dynamic duo carry torch for future CRC screening </a> <a title="EMJ Gastroenterology 2014 page 24" href="http://viewer.zmags.com/publication/6efed8a9?page=24"> UEG WEEK ANNUAL CONGRESS 2014 AUSTRIA CENTER VIEN</a> <a title="EMJ Gastroenterology 2014 page 25" href="http://viewer.zmags.com/publication/6efed8a9?page=25"> CORTIMENT®: standing up to ulcerative colitis A </a> <a title="EMJ Gastroenterology 2014 page 26" href="http://viewer.zmags.com/publication/6efed8a9?page=26"> UEG WEEK ANNUAL CONGRESS 2014 AUSTRIA CENTER VIEN</a> <a title="EMJ Gastroenterology 2014 page 27" href="http://viewer.zmags.com/publication/6efed8a9?page=27"> Call for personalised approach in primary care dy</a> <a title="EMJ Gastroenterology 2014 page 28" href="http://viewer.zmags.com/publication/6efed8a9?page=28"> UEG WEEK ANNUAL CONGRESS 2014 AUSTRIA CENTER VIEN</a> <a title="EMJ Gastroenterology 2014 page 29" href="http://viewer.zmags.com/publication/6efed8a9?page=29"> Greater gastrointestinal understanding just a cli</a> <a title="EMJ Gastroenterology 2014 page 30" href="http://viewer.zmags.com/publication/6efed8a9?page=30"> UEG WEEK ANNUAL CONGRESS 2014 AUSTRIA CENTER VIEN</a> <a title="EMJ Gastroenterology 2014 page 31" href="http://viewer.zmags.com/publication/6efed8a9?page=31"> Doctors debate over Helicobacter pylori strategy </a> <a title="EMJ Gastroenterology 2014 page 32" href="http://viewer.zmags.com/publication/6efed8a9?page=32"> UEG WEEK ANNUAL CONGRESS 2014 AUSTRIA CENTER VIEN</a> <a title="EMJ Gastroenterology 2014 page 33" href="http://viewer.zmags.com/publication/6efed8a9?page=33"> Hands-off approach to alcoholic liver disease dia</a> <a title="EMJ Gastroenterology 2014 page 34" href="http://viewer.zmags.com/publication/6efed8a9?page=34"> UEG WEEK ANNUAL CONGRESS 2014 AUSTRIA CENTER VIEN</a> <a title="EMJ Gastroenterology 2014 page 35" href="http://viewer.zmags.com/publication/6efed8a9?page=35"> </a> <a title="EMJ Gastroenterology 2014 page 36" href="http://viewer.zmags.com/publication/6efed8a9?page=36"> HIGHLIGHTS FROM THE UEG WEEK CONGRESS 2014: </a> <a title="EMJ Gastroenterology 2014 page 37" href="http://viewer.zmags.com/publication/6efed8a9?page=37"> management of IBS. The UEG Week Congress ga</a> <a title="EMJ Gastroenterology 2014 page 38" href="http://viewer.zmags.com/publication/6efed8a9?page=38"> 13-acetate/ionomycin (PMA/I). At each visit, the </a> <a title="EMJ Gastroenterology 2014 page 39" href="http://viewer.zmags.com/publication/6efed8a9?page=39"> the EMA in 2012 for the treatment of IBS-C as it </a> <a title="EMJ Gastroenterology 2014 page 40" href="http://viewer.zmags.com/publication/6efed8a9?page=40"> altered bowel movements. However, three previous </a> <a title="EMJ Gastroenterology 2014 page 41" href="http://viewer.zmags.com/publication/6efed8a9?page=41"> abdominal symptoms and constipation in IBS-C</a> <a title="EMJ Gastroenterology 2014 page 42" href="http://viewer.zmags.com/publication/6efed8a9?page=42"> A PROKINETIC AGENT WITH A DUAL EFFECT – ITOPRID</a> <a title="EMJ Gastroenterology 2014 page 43" href="http://viewer.zmags.com/publication/6efed8a9?page=43"> CHARACTERISTICS OF ITOPRIDE Itopride is a pro</a> <a title="EMJ Gastroenterology 2014 page 44" href="http://viewer.zmags.com/publication/6efed8a9?page=44"> All three doses of itopride demonstrate</a> <a title="EMJ Gastroenterology 2014 page 45" href="http://viewer.zmags.com/publication/6efed8a9?page=45"> effect in healthy persons may be different from t</a> <a title="EMJ Gastroenterology 2014 page 46" href="http://viewer.zmags.com/publication/6efed8a9?page=46"> DD2Rs; itopride is extremely rapidly absorbed, an</a> <a title="EMJ Gastroenterology 2014 page 47" href="http://viewer.zmags.com/publication/6efed8a9?page=47"> itopride combined with lansoprazole in patients </a> <a title="EMJ Gastroenterology 2014 page 48" href="http://viewer.zmags.com/publication/6efed8a9?page=48"> - VSL#3® contains the highest concentration of li</a> <a title="EMJ Gastroenterology 2014 page 49" href="http://viewer.zmags.com/publication/6efed8a9?page=49"> RISKS OF USING BEDSIDE TESTS TO VERIFY NAS</a> <a title="EMJ Gastroenterology 2014 page 50" href="http://viewer.zmags.com/publication/6efed8a9?page=50"> (cut-off 5.5) and the use of chest radiogr</a> <a title="EMJ Gastroenterology 2014 page 51" href="http://viewer.zmags.com/publication/6efed8a9?page=51"> together to verify tube site, was simply the prod</a> <a title="EMJ Gastroenterology 2014 page 52" href="http://viewer.zmags.com/publication/6efed8a9?page=52"> Table 1: Sensitivity of the bedside tests in posi</a> <a title="EMJ Gastroenterology 2014 page 53" href="http://viewer.zmags.com/publication/6efed8a9?page=53"> Table 2(**) presents the LRs based on test validi</a> <a title="EMJ Gastroenterology 2014 page 54" href="http://viewer.zmags.com/publication/6efed8a9?page=54"> sites, whereas a pH test with cut-offs at 5.5 or </a> <a title="EMJ Gastroenterology 2014 page 55" href="http://viewer.zmags.com/publication/6efed8a9?page=55"> incidents of pneumothorax among 187 tub</a> <a title="EMJ Gastroenterology 2014 page 56" href="http://viewer.zmags.com/publication/6efed8a9?page=56"> 2000;49(6):302-9. 16. Metheny NA, Titler MG. </a> <a title="EMJ Gastroenterology 2014 page 57" href="http://viewer.zmags.com/publication/6efed8a9?page=57"> DIAGNOSTIC METHODS IN EOSINOPHILIC OES</a> <a title="EMJ Gastroenterology 2014 page 58" href="http://viewer.zmags.com/publication/6efed8a9?page=58"> The lack of consensus on the follow-up of </a> <a title="EMJ Gastroenterology 2014 page 59" href="http://viewer.zmags.com/publication/6efed8a9?page=59"> Table 1: Histologic signs of eosinophilic oesopha</a> <a title="EMJ Gastroenterology 2014 page 60" href="http://viewer.zmags.com/publication/6efed8a9?page=60"> frequency probes, it has been found that there ar</a> <a title="EMJ Gastroenterology 2014 page 61" href="http://viewer.zmags.com/publication/6efed8a9?page=61"> seen in those patients that showed alterations on</a> <a title="EMJ Gastroenterology 2014 page 62" href="http://viewer.zmags.com/publication/6efed8a9?page=62"> Acknowledgement We appreciate the contributions o</a> <a title="EMJ Gastroenterology 2014 page 63" href="http://viewer.zmags.com/publication/6efed8a9?page=63"> longitudinal muscles of the oesophagus in eosi</a> <a title="EMJ Gastroenterology 2014 page 64" href="http://viewer.zmags.com/publication/6efed8a9?page=64"> UPDATE ON BARRETT’S OESOPHAGUS Claudia Tarlar</a> <a title="EMJ Gastroenterology 2014 page 65" href="http://viewer.zmags.com/publication/6efed8a9?page=65"> particular salmon-pink colour and a coarse textur</a> <a title="EMJ Gastroenterology 2014 page 66" href="http://viewer.zmags.com/publication/6efed8a9?page=66"> Genetic background Alcohol and smoking GERD</a> <a title="EMJ Gastroenterology 2014 page 67" href="http://viewer.zmags.com/publication/6efed8a9?page=67"> which will produce other cytokines, inducing</a> <a title="EMJ Gastroenterology 2014 page 68" href="http://viewer.zmags.com/publication/6efed8a9?page=68"> patients to undergo treatment with aspirin and es</a> <a title="EMJ Gastroenterology 2014 page 69" href="http://viewer.zmags.com/publication/6efed8a9?page=69"> Smoking status was analysed together with the gen</a> <a title="EMJ Gastroenterology 2014 page 70" href="http://viewer.zmags.com/publication/6efed8a9?page=70"> destroys the mucosa of BO patients. RFA appears a</a> <a title="EMJ Gastroenterology 2014 page 71" href="http://viewer.zmags.com/publication/6efed8a9?page=71"> 2003;125(6):1670-7. 6. Rodríguez-Díjesús A et al.</a> <a title="EMJ Gastroenterology 2014 page 72" href="http://viewer.zmags.com/publication/6efed8a9?page=72"> Gastroenterol Hepatol. 2012;24(8):917-23. 51. Da</a> <a title="EMJ Gastroenterology 2014 page 73" href="http://viewer.zmags.com/publication/6efed8a9?page=73"> THE MANAGEMENT OF ACUTE UPPER G</a> <a title="EMJ Gastroenterology 2014 page 74" href="http://viewer.zmags.com/publication/6efed8a9?page=74"> from gastric or oesophageal varicosities, mo</a> <a title="EMJ Gastroenterology 2014 page 75" href="http://viewer.zmags.com/publication/6efed8a9?page=75"> exsanguinations.24 Initial risk stratification is </a> <a title="EMJ Gastroenterology 2014 page 76" href="http://viewer.zmags.com/publication/6efed8a9?page=76"> Several risk classification systems have been</a> <a title="EMJ Gastroenterology 2014 page 77" href="http://viewer.zmags.com/publication/6efed8a9?page=77"> Table 2: Summary of the current recommendations f</a> <a title="EMJ Gastroenterology 2014 page 78" href="http://viewer.zmags.com/publication/6efed8a9?page=78"> In this classification, Grade 1 is for active blee</a> <a title="EMJ Gastroenterology 2014 page 79" href="http://viewer.zmags.com/publication/6efed8a9?page=79"> occurs at an annual rate of 5-15%.1 Despite the h</a> <a title="EMJ Gastroenterology 2014 page 80" href="http://viewer.zmags.com/publication/6efed8a9?page=80"> Seminal work in 1985 by Rimola et al.54 first show</a> <a title="EMJ Gastroenterology 2014 page 81" href="http://viewer.zmags.com/publication/6efed8a9?page=81"> the risk of re-bleeding. For patients with suspec</a> <a title="EMJ Gastroenterology 2014 page 82" href="http://viewer.zmags.com/publication/6efed8a9?page=82"> Database Syst Rev. 2010;(7):CD005415. 37. Forres</a> <a title="EMJ Gastroenterology 2014 page 83" href="http://viewer.zmags.com/publication/6efed8a9?page=83"> Fuse® Full Spectrum Endoscopy Advancing Your GI P</a> <a title="EMJ Gastroenterology 2014 page 84" href="http://viewer.zmags.com/publication/6efed8a9?page=84"> SMALL INTESTINAL TUMOURS: AN OVERVIEW ON CLASSIF</a> <a title="EMJ Gastroenterology 2014 page 85" href="http://viewer.zmags.com/publication/6efed8a9?page=85"> - FAP: this autosomal dominant condition is</a> <a title="EMJ Gastroenterology 2014 page 86" href="http://viewer.zmags.com/publication/6efed8a9?page=86"> reflecting the higher concentration of bile </a> <a title="EMJ Gastroenterology 2014 page 87" href="http://viewer.zmags.com/publication/6efed8a9?page=87"> small intestine lymphomas are coeliac diseas</a> <a title="EMJ Gastroenterology 2014 page 88" href="http://viewer.zmags.com/publication/6efed8a9?page=88"> endoscopy, attainment of a histology specime</a> <a title="EMJ Gastroenterology 2014 page 89" href="http://viewer.zmags.com/publication/6efed8a9?page=89"> Neoadjuvant therapy should be used </a> <a title="EMJ Gastroenterology 2014 page 90" href="http://viewer.zmags.com/publication/6efed8a9?page=90"> GISTs Surgery is the treatment of choice for GIST</a> <a title="EMJ Gastroenterology 2014 page 91" href="http://viewer.zmags.com/publication/6efed8a9?page=91"> precancerous lesions in the small bowel mucosa. B</a> <a title="EMJ Gastroenterology 2014 page 92" href="http://viewer.zmags.com/publication/6efed8a9?page=92"> melanoma of the small intestine. Gastroen</a> <a title="EMJ Gastroenterology 2014 page 93" href="http://viewer.zmags.com/publication/6efed8a9?page=93"> Radiology. 2000;216(3):758-63. 111. Woodall CE et</a> <a title="EMJ Gastroenterology 2014 page 94" href="http://viewer.zmags.com/publication/6efed8a9?page=94"> THE GEOGRAPHIC VARIANCE OF HELICOBACTER PYLORI I</a> <a title="EMJ Gastroenterology 2014 page 95" href="http://viewer.zmags.com/publication/6efed8a9?page=95"> infections can be diagnosed by a variety of tests</a> <a title="EMJ Gastroenterology 2014 page 96" href="http://viewer.zmags.com/publication/6efed8a9?page=96"> Table 1: The prevalence of Helicobacter pylori in</a> <a title="EMJ Gastroenterology 2014 page 97" href="http://viewer.zmags.com/publication/6efed8a9?page=97"> Table 2: Helicobacter pylori prevalence in adults</a> <a title="EMJ Gastroenterology 2014 page 98" href="http://viewer.zmags.com/publication/6efed8a9?page=98"> Turkey Latvia Spain Germany UK Belgium Sweden Slo</a> <a title="EMJ Gastroenterology 2014 page 99" href="http://viewer.zmags.com/publication/6efed8a9?page=99"> Kivi et al.52 studied Helicobacter status in fami</a> <a title="EMJ Gastroenterology 2014 page 100" href="http://viewer.zmags.com/publication/6efed8a9?page=100"> et al.61 reported that alcohol consumption </a> <a title="EMJ Gastroenterology 2014 page 101" href="http://viewer.zmags.com/publication/6efed8a9?page=101"> influence on growth. An Pediatr (Barc). 2005;63(6)</a> <a title="EMJ Gastroenterology 2014 page 102" href="http://viewer.zmags.com/publication/6efed8a9?page=102"> 2013. Available at: http:/www.cdc.gov/ media/rele</a> <a title="EMJ Gastroenterology 2014 page 103" href="http://viewer.zmags.com/publication/6efed8a9?page=103"> MANAGING COMPLICATED DIVERTICULAR </a> <a title="EMJ Gastroenterology 2014 page 104" href="http://viewer.zmags.com/publication/6efed8a9?page=104"> radiology, endoscopy, as well as other minimally </a> <a title="EMJ Gastroenterology 2014 page 105" href="http://viewer.zmags.com/publication/6efed8a9?page=105"> material through the drain is recommend</a> <a title="EMJ Gastroenterology 2014 page 106" href="http://viewer.zmags.com/publication/6efed8a9?page=106"> perforated diverticulitis may be perf</a> <a title="EMJ Gastroenterology 2014 page 107" href="http://viewer.zmags.com/publication/6efed8a9?page=107"> CONCLUSION In conclusion, complicated DD has man</a> <a title="EMJ Gastroenterology 2014 page 108" href="http://viewer.zmags.com/publication/6efed8a9?page=108"> 37. St Vincent’s University Hospital, Ire</a> <a title="EMJ Gastroenterology 2014 page 109" href="http://viewer.zmags.com/publication/6efed8a9?page=109"> Would you like to write for the EMJ blog? Intera</a> <a title="EMJ Gastroenterology 2014 page 110" href="http://viewer.zmags.com/publication/6efed8a9?page=110"> WHAT’S NEW Botox: giving you more than just a pre</a> <a title="EMJ Gastroenterology 2014 page 111" href="http://viewer.zmags.com/publication/6efed8a9?page=111"> GASTROENTEROLOGY Electric pulse beats knife as li</a> <a title="EMJ Gastroenterology 2014 page 112" href="http://viewer.zmags.com/publication/6efed8a9?page=112"> WHAT’S NEW Insulin guards against pancreatitis </a> <a title="EMJ Gastroenterology 2014 page 113" href="http://viewer.zmags.com/publication/6efed8a9?page=113"> GASTROENTEROLOGY Spotted through blood test: Croh</a> <a title="EMJ Gastroenterology 2014 page 114" href="http://viewer.zmags.com/publication/6efed8a9?page=114"> WHAT’S NEW Rodent revolution aids war on liver di</a> <a title="EMJ Gastroenterology 2014 page 115" href="http://viewer.zmags.com/publication/6efed8a9?page=115"> GASTROENTEROLOGY Sharing is caring after all, for</a> <a title="EMJ Gastroenterology 2014 page 116" href="http://viewer.zmags.com/publication/6efed8a9?page=116"> WHAT’S NEW Infiltrative drug is good news for Croh</a> <a title="EMJ Gastroenterology 2014 page 117" href="http://viewer.zmags.com/publication/6efed8a9?page=117"> GASTROENTEROLOGY UK hit hardest for oesophageal c</a> <a title="EMJ Gastroenterology 2014 page 118" href="http://viewer.zmags.com/publication/6efed8a9?page=118"> WHAT’S NEW Drug discovery could spell BAD news fo</a> <a title="EMJ Gastroenterology 2014 page 119" href="http://viewer.zmags.com/publication/6efed8a9?page=119"> GASTROENTEROLOGY Growing an intestine for GI dise</a> <a title="EMJ Gastroenterology 2014 page 120" href="http://viewer.zmags.com/publication/6efed8a9?page=120"> WHAT’S NEW Buzz off cancer! “Our results in fr</a> <a title="EMJ Gastroenterology 2014 page 121" href="http://viewer.zmags.com/publication/6efed8a9?page=121"> SUBSCRIBE FREE TO OUR YOUTUBE CHANNEL www.youtube</a> <a title="EMJ Gastroenterology 2014 page 122" href="http://viewer.zmags.com/publication/6efed8a9?page=122"> Featured Suppliers Gastroenterology Endochoice </a> <a title="EMJ Gastroenterology 2014 page 123" href="http://viewer.zmags.com/publication/6efed8a9?page=123"> SUBSCRIBE TO THE EMJ NEWSLETTER www.news.emjrevie</a> <a title="EMJ Gastroenterology 2014 page 124" href="http://viewer.zmags.com/publication/6efed8a9?page=124"> Buyer’s Guide Exhibitors • 3-D MATRIX EUROPE SA</a> <a title="EMJ Gastroenterology 2014 page 125" href="http://viewer.zmags.com/publication/6efed8a9?page=125"> Gastroenterology • HANGZHOU AGS MEDTECH CO.,</a> <a title="EMJ Gastroenterology 2014 page 126" href="http://viewer.zmags.com/publication/6efed8a9?page=126"> UPCOMING EVENTS European School of Oncology-Euro</a> <a title="EMJ Gastroenterology 2014 page 127" href="http://viewer.zmags.com/publication/6efed8a9?page=127"> GASTROENTEROLOGY European Society of Gastrointes</a> <a title="EMJ Gastroenterology 2014 page 128" href="http://viewer.zmags.com/publication/6efed8a9?page=128"> SUBSCRIBE TO RECEIVE THE LATEST CATIONS PUBLI</a>