If you are visually impaired or blind, you can visit the PDF version by Pressing CONTROL + ALT + 4
<br /> ARCHIVE<br /> VOLUME 113 NUMBER 1 JANUARY 2018<br /> www.nature.com/ajg<br /> OFFICIAL PUBLICATION OF THE AMERICAN COLLEGE OF GASTROENTEROLOGY<br /> EDITORS: Brian E. Lacy, PhD, MD, FACG and Brennan Spiegel, MD, MSHS, FACG<br /> January 2018<br /> AJG_Cover-Special-issue2017_v3.indd 112/19/17 3:10 PM<br /> 2014 2015<br /> VOLUME 113 NUMBER 2 FEBRUARY 2018<br /> www.nature.com/ajg<br /> OFFICIAL PUBLICATION OF THE AMERICAN COLLEGE OF GASTROENTEROLOGY<br /> LEADING ARTICLES OF THE MONTH<br /> ACG Clinical Guideline<br /> 175 ACG Clinical Guideline: Alcoholic Liver Disease CME<br /> Ashwani K. Singal, Ramon Bataller, Joseph Ahn, Patrick S. Kamath and<br /> Vijay H. Shah<br /> Esophagus<br /> 196 Timed Barium Swallow: Diagnostic Role and Predictive Value in<br /> Untreated Achalasia, Esophagogastric Junction Outflow Obstruction,<br /> and Non-Achalasia Dysphagia CME<br /> <a title="AJG_Vol.113.No3 page 1" href="http://viewer.zmags.com/publication/777bab68?page=1"> ARCHIVE VOLUME 113 NUMBER 1 JANUARY 2018 www.na</a> <a title="AJG_Vol.113.No3 page 2" href="http://viewer.zmags.com/publication/777bab68?page=2"> VOLUME 113 NUMBER 3 MARCH 2018 www.nature.com/ajg</a> <a title="AJG_Vol.113.No3 page 3" href="http://viewer.zmags.com/publication/777bab68?page=3"> INDICATIONS Adult Ulcerative Colitis (UC) ENTYVIO</a> <a title="AJG_Vol.113.No3 page 4" href="http://viewer.zmags.com/publication/777bab68?page=4"> In UC & CD FOR ADULTS WITH MODERATELY TO SEVEREL</a> <a title="AJG_Vol.113.No3 page 5" href="http://viewer.zmags.com/publication/777bab68?page=5"> BRIEF SUMMARY OF FULL PRESCRIBING INFORMATION ENT</a> <a title="AJG_Vol.113.No3 page 6" href="http://viewer.zmags.com/publication/777bab68?page=6"> Table 1. Adverse Reactions in ≥3% of ENTYVIO-trea</a> <a title="AJG_Vol.113.No3 page 7" href="http://viewer.zmags.com/publication/777bab68?page=7"> by several factors, including sample handling, ti</a> <a title="AJG_Vol.113.No3 page 8" href="http://viewer.zmags.com/publication/777bab68?page=8"> www.nature.com/ajg The American Journal o</a> <a title="AJG_Vol.113.No3 page 9" href="http://viewer.zmags.com/publication/777bab68?page=9"> official publication of the american college</a> <a title="AJG_Vol.113.No3 page 10" href="http://viewer.zmags.com/publication/777bab68?page=10"> 65 Years of GI Endoscopy Innovation in One Powerf</a> <a title="AJG_Vol.113.No3 page 11" href="http://viewer.zmags.com/publication/777bab68?page=11"> </a> <a title="AJG_Vol.113.No3 page 12" href="http://viewer.zmags.com/publication/777bab68?page=12"> </a> <a title="AJG_Vol.113.No3 page 13" href="http://viewer.zmags.com/publication/777bab68?page=13"> </a> <a title="AJG_Vol.113.No3 page 14" href="http://viewer.zmags.com/publication/777bab68?page=14"> </a> <a title="AJG_Vol.113.No3 page 15" href="http://viewer.zmags.com/publication/777bab68?page=15"> ® Look Below the Surface Molecular Testin</a> <a title="AJG_Vol.113.No3 page 16" href="http://viewer.zmags.com/publication/777bab68?page=16"> INTEGRATIVE CONFERENCE Speaker</a> <a title="AJG_Vol.113.No3 page 17" href="http://viewer.zmags.com/publication/777bab68?page=17"> For first-line constipation therapy, stick with t</a> <a title="AJG_Vol.113.No3 page 18" href="http://viewer.zmags.com/publication/777bab68?page=18"> A 20-mm, flat, nongranular, laterally spreading le</a> <a title="AJG_Vol.113.No3 page 19" href="http://viewer.zmags.com/publication/777bab68?page=19"> CONTENTS </a> <a title="AJG_Vol.113.No3 page 20" href="http://viewer.zmags.com/publication/777bab68?page=20"> www.nature.com/ajg </a> <a title="AJG_Vol.113.No3 page 21" href="http://viewer.zmags.com/publication/777bab68?page=21"> Attend an upcoming 2018 ACG POSTGRADUATE COURS</a> <a title="AJG_Vol.113.No3 page 22" href="http://viewer.zmags.com/publication/777bab68?page=22"> Learn more at WWW.MAVYRET.COM FOR CHRONIC HCV I</a> <a title="AJG_Vol.113.No3 page 23" href="http://viewer.zmags.com/publication/777bab68?page=23"> MAVYRETTM (glecaprevir and pibrentasvir) tablets,</a> <a title="AJG_Vol.113.No3 page 24" href="http://viewer.zmags.com/publication/777bab68?page=24"> No adverse embryo-fetal effects were observed in </a> <a title="AJG_Vol.113.No3 page 25" href="http://viewer.zmags.com/publication/777bab68?page=25"> RENFLEXIS TM (infliximab-abda) The in iximab </a> <a title="AJG_Vol.113.No3 page 26" href="http://viewer.zmags.com/publication/777bab68?page=26"> FDA-approved as a biosimilar to Remicade® (in ixi</a> <a title="AJG_Vol.113.No3 page 27" href="http://viewer.zmags.com/publication/777bab68?page=27"> Brief Summary of the Prescribing Information for </a> <a title="AJG_Vol.113.No3 page 28" href="http://viewer.zmags.com/publication/777bab68?page=28"> Brief Summary of the Prescribing Information for </a> <a title="AJG_Vol.113.No3 page 29" href="http://viewer.zmags.com/publication/777bab68?page=29"> Brief Summary of the Prescribing Information for </a> <a title="AJG_Vol.113.No3 page 30" href="http://viewer.zmags.com/publication/777bab68?page=30"> Brief Summary of the Prescribing Information for </a> <a title="AJG_Vol.113.No3 page 31" href="http://viewer.zmags.com/publication/777bab68?page=31"> 2018 ACG AWARD NOMINATIONS Honor Your Colleague </a> <a title="AJG_Vol.113.No3 page 32" href="http://viewer.zmags.com/publication/777bab68?page=32"> Sofosbuvir-based therapy changed expectations in </a> <a title="AJG_Vol.113.No3 page 33" href="http://viewer.zmags.com/publication/777bab68?page=33"> FOR TREATING CHRONIC HCV GT 1 BE THE ONE WHO </a> <a title="AJG_Vol.113.No3 page 34" href="http://viewer.zmags.com/publication/777bab68?page=34"> FOR TREATING CHRONIC HCV EXPAND WHAT'S POSSIBL</a> <a title="AJG_Vol.113.No3 page 35" href="http://viewer.zmags.com/publication/777bab68?page=35"> HARVONI® (ledipasvir 90 mg and sofosbuvir 400 mg)</a> <a title="AJG_Vol.113.No3 page 36" href="http://viewer.zmags.com/publication/777bab68?page=36"> Brief Summary (cont.) •Laboratory Abnormalities</a> <a title="AJG_Vol.113.No3 page 37" href="http://viewer.zmags.com/publication/777bab68?page=37"> EPCLUSA® (sofosbuvir 400 mg and velpatasvir 100 m</a> <a title="AJG_Vol.113.No3 page 38" href="http://viewer.zmags.com/publication/777bab68?page=38"> Brief Summary (cont.) In ASTRAL-1, isolated, asym</a> <a title="AJG_Vol.113.No3 page 39" href="http://viewer.zmags.com/publication/777bab68?page=39"> Indication Trulance (plecanatide) 3 mg tablets is</a> <a title="AJG_Vol.113.No3 page 40" href="http://viewer.zmags.com/publication/777bab68?page=40"> For adults with Chronic Idiopathic Constipation (</a> <a title="AJG_Vol.113.No3 page 41" href="http://viewer.zmags.com/publication/777bab68?page=41"> Trulance® (plecanatide) tablets, for oral use Rx </a> <a title="AJG_Vol.113.No3 page 42" href="http://viewer.zmags.com/publication/777bab68?page=42"> In nonclinical studies, deaths occurred within 24</a> <a title="AJG_Vol.113.No3 page 43" href="http://viewer.zmags.com/publication/777bab68?page=43"> RECOMMEND THE BEST WITH NEXIUM® 24HR Nexium® 24HR</a> <a title="AJG_Vol.113.No3 page 44" href="http://viewer.zmags.com/publication/777bab68?page=44"> THE RED SECTION 313 see related editorial</a> <a title="AJG_Vol.113.No3 page 45" href="http://viewer.zmags.com/publication/777bab68?page=45"> 314 THE RED SECTION anti-gravity (opposite</a> <a title="AJG_Vol.113.No3 page 46" href="http://viewer.zmags.com/publication/777bab68?page=46"> THE RED SECTION 315 Figure</a> <a title="AJG_Vol.113.No3 page 47" href="http://viewer.zmags.com/publication/777bab68?page=47"> 316 THE RED SECTION HOW I APPROACH IT Table </a> <a title="AJG_Vol.113.No3 page 48" href="http://viewer.zmags.com/publication/777bab68?page=48"> THE RED SECTION 317 see related editorial</a> <a title="AJG_Vol.113.No3 page 49" href="http://viewer.zmags.com/publication/777bab68?page=49"> 318 THE RED SECTION QUALITY MATTERS manageme</a> <a title="AJG_Vol.113.No3 page 50" href="http://viewer.zmags.com/publication/777bab68?page=50"> with the patient, with ample time allotted, with </a> <a title="AJG_Vol.113.No3 page 51" href="http://viewer.zmags.com/publication/777bab68?page=51"> 320 THE RED SECTION QUALITY MATTERS to the w</a> <a title="AJG_Vol.113.No3 page 52" href="http://viewer.zmags.com/publication/777bab68?page=52"> misleading name often leads to an unnecess</a> <a title="AJG_Vol.113.No3 page 53" href="http://viewer.zmags.com/publication/777bab68?page=53"> 322 THE RED SECTION POINT-COUNTERPOINT The s</a> <a title="AJG_Vol.113.No3 page 54" href="http://viewer.zmags.com/publication/777bab68?page=54"> Table 1. Factors which predict successful TPIAT i</a> <a title="AJG_Vol.113.No3 page 55" href="http://viewer.zmags.com/publication/777bab68?page=55"> 324 THE RED SECTION POINT COUNTERPOINT Patie</a> <a title="AJG_Vol.113.No3 page 56" href="http://viewer.zmags.com/publication/777bab68?page=56"> THE RED SECTION 325 a Tr</a> <a title="AJG_Vol.113.No3 page 57" href="http://viewer.zmags.com/publication/777bab68?page=57"> 326 THE RED SECTION POINT COUNTERPOINT 9. M</a> <a title="AJG_Vol.113.No3 page 58" href="http://viewer.zmags.com/publication/777bab68?page=58"> THE RED SECTION 327 Images of the Month An</a> <a title="AJG_Vol.113.No3 page 59" href="http://viewer.zmags.com/publication/777bab68?page=59"> 328 THE RED SECTION Video of the Month Com</a> <a title="AJG_Vol.113.No3 page 60" href="http://viewer.zmags.com/publication/777bab68?page=60"> CLINICAL AND SYSTEMATIC REVIEWS 329 CME E</a> <a title="AJG_Vol.113.No3 page 61" href="http://viewer.zmags.com/publication/777bab68?page=61"> 330 Shah et al. REVIEW have been investigat</a> <a title="AJG_Vol.113.No3 page 62" href="http://viewer.zmags.com/publication/777bab68?page=62"> Study endpoints for meta-analysis Our co-primary </a> <a title="AJG_Vol.113.No3 page 63" href="http://viewer.zmags.com/publication/777bab68?page=63"> 332 Shah et al. REVIEW Abstracts/trials ide</a> <a title="AJG_Vol.113.No3 page 64" href="http://viewer.zmags.com/publication/777bab68?page=64"> Systematic Review of GCC agonists in IBS-C and CI</a> <a title="AJG_Vol.113.No3 page 65" href="http://viewer.zmags.com/publication/777bab68?page=65"> 334 Shah et al. a CIC </a> <a title="AJG_Vol.113.No3 page 66" href="http://viewer.zmags.com/publication/777bab68?page=66"> Systematic Review of GCC agonists in IBS-C and CI</a> <a title="AJG_Vol.113.No3 page 67" href="http://viewer.zmags.com/publication/777bab68?page=67"> 336 Shah et al. REVIEW Table 1. Results of </a> <a title="AJG_Vol.113.No3 page 68" href="http://viewer.zmags.com/publication/777bab68?page=68"> ACKNOWLEDGMENTS This material is the result of wo</a> <a title="AJG_Vol.113.No3 page 69" href="http://viewer.zmags.com/publication/777bab68?page=69"> 338 Shah et al. REVIEW 25. Schoenfeld P, La</a> <a title="AJG_Vol.113.No3 page 70" href="http://viewer.zmags.com/publication/777bab68?page=70"> CLINICAL AND SYSTEMATIC REVIEWS 339 CME </a> <a title="AJG_Vol.113.No3 page 71" href="http://viewer.zmags.com/publication/777bab68?page=71"> 340 Adelman et al. REVIEW patients have no </a> <a title="AJG_Vol.113.No3 page 72" href="http://viewer.zmags.com/publication/777bab68?page=72"> Histologic Measures in Celiac Disease 341 </a> <a title="AJG_Vol.113.No3 page 73" href="http://viewer.zmags.com/publication/777bab68?page=73"> 342 Adelman et al. REVIEW Table 2. Small bo</a> <a title="AJG_Vol.113.No3 page 74" href="http://viewer.zmags.com/publication/777bab68?page=74"> Histologic Measures in Celiac Disease 343 REV</a> <a title="AJG_Vol.113.No3 page 75" href="http://viewer.zmags.com/publication/777bab68?page=75"> 344 Adelman et al. REVIEW Table 3. Comparis</a> <a title="AJG_Vol.113.No3 page 76" href="http://viewer.zmags.com/publication/777bab68?page=76"> Histologic Measures in Celiac Disease 345 </a> <a title="AJG_Vol.113.No3 page 77" href="http://viewer.zmags.com/publication/777bab68?page=77"> 346 Adelman et al. REVIEW mucosal architect</a> <a title="AJG_Vol.113.No3 page 78" href="http://viewer.zmags.com/publication/777bab68?page=78"> REFERENCES 1. Schuppan D, Junker Y, Barisani D. </a> <a title="AJG_Vol.113.No3 page 79" href="http://viewer.zmags.com/publication/777bab68?page=79"> 348 ORIGINAL CONTRIBUTIONS see related ed</a> <a title="AJG_Vol.113.No3 page 80" href="http://viewer.zmags.com/publication/777bab68?page=80"> INTRODUCTION Eosinophilic esophagitis (EoE) is a </a> <a title="AJG_Vol.113.No3 page 81" href="http://viewer.zmags.com/publication/777bab68?page=81"> 350 Schoepfer et al. ESOPHAGUS endoscopic f</a> <a title="AJG_Vol.113.No3 page 82" href="http://viewer.zmags.com/publication/777bab68?page=82"> Subepithelial Eosinophils in EoE 351 Table </a> <a title="AJG_Vol.113.No3 page 83" href="http://viewer.zmags.com/publication/777bab68?page=83"> 352 Schoepfer et al. ESOPHAGUS Table 2. Rel</a> <a title="AJG_Vol.113.No3 page 84" href="http://viewer.zmags.com/publication/777bab68?page=84"> Subepithelial Eosinophils in EoE 353 Categ</a> <a title="AJG_Vol.113.No3 page 85" href="http://viewer.zmags.com/publication/777bab68?page=85"> 354 Schoepfer et al. ESOPHAGUS Table 3. Ana</a> <a title="AJG_Vol.113.No3 page 86" href="http://viewer.zmags.com/publication/777bab68?page=86"> In this study, we found that patients with higher</a> <a title="AJG_Vol.113.No3 page 87" href="http://viewer.zmags.com/publication/777bab68?page=87"> 356 Schoepfer et al. ESOPHAGUS Dagmar Simon</a> <a title="AJG_Vol.113.No3 page 88" href="http://viewer.zmags.com/publication/777bab68?page=88"> 27. Straumann A, Aceves SS, Blanchard C et al. Pe</a> <a title="AJG_Vol.113.No3 page 89" href="http://viewer.zmags.com/publication/777bab68?page=89"> 358 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.113.No3 page 90" href="http://viewer.zmags.com/publication/777bab68?page=90"> factors associated with need for urgent hemostati</a> <a title="AJG_Vol.113.No3 page 91" href="http://viewer.zmags.com/publication/777bab68?page=91"> 360 Laine et al. STOMACH breakpoints for he</a> <a title="AJG_Vol.113.No3 page 92" href="http://viewer.zmags.com/publication/777bab68?page=92"> Table 2. Indicators of bleeding severity and pred</a> <a title="AJG_Vol.113.No3 page 93" href="http://viewer.zmags.com/publication/777bab68?page=93"> 362 Laine et al. STOMACH Table 4. Compariso</a> <a title="AJG_Vol.113.No3 page 94" href="http://viewer.zmags.com/publication/777bab68?page=94"> Bloody Vs. Coffee-Grounds Hematemesis 363 T</a> <a title="AJG_Vol.113.No3 page 95" href="http://viewer.zmags.com/publication/777bab68?page=95"> 364 Laine et al. STOMACH intervention, and </a> <a title="AJG_Vol.113.No3 page 96" href="http://viewer.zmags.com/publication/777bab68?page=96"> concurrent melena was associated with nearly a th</a> <a title="AJG_Vol.113.No3 page 97" href="http://viewer.zmags.com/publication/777bab68?page=97"> 366 Laine et al. STOMACH 11. Stanley AJ, La</a> <a title="AJG_Vol.113.No3 page 98" href="http://viewer.zmags.com/publication/777bab68?page=98"> CONTINUING MEDICAL EDUCATION 367 CME Con</a> <a title="AJG_Vol.113.No3 page 99" href="http://viewer.zmags.com/publication/777bab68?page=99"> 368 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.113.No3 page 100" href="http://viewer.zmags.com/publication/777bab68?page=100"> failure (8). In accordance with this, there is no</a> <a title="AJG_Vol.113.No3 page 101" href="http://viewer.zmags.com/publication/777bab68?page=101"> 370 Basili et al. LIVER RESULTS Overall, 28</a> <a title="AJG_Vol.113.No3 page 102" href="http://viewer.zmags.com/publication/777bab68?page=102"> Platelet Count and Bleeding in Cirrhosis 371 </a> <a title="AJG_Vol.113.No3 page 103" href="http://viewer.zmags.com/publication/777bab68?page=103"> 372 Basili et al. LIVER Table 3. Clinical c</a> <a title="AJG_Vol.113.No3 page 104" href="http://viewer.zmags.com/publication/777bab68?page=104"> Table 5. Multivariate analyses according to the i</a> <a title="AJG_Vol.113.No3 page 105" href="http://viewer.zmags.com/publication/777bab68?page=105"> 374 Basili et al. therapy for patients wi</a> <a title="AJG_Vol.113.No3 page 106" href="http://viewer.zmags.com/publication/777bab68?page=106"> Study Highlights WHAT IS CURRENT KNOWLEDGE ✓ Cir</a> <a title="AJG_Vol.113.No3 page 107" href="http://viewer.zmags.com/publication/777bab68?page=107"> 376 ORIGINAL CONTRIBUTIONS see related e</a> <a title="AJG_Vol.113.No3 page 108" href="http://viewer.zmags.com/publication/777bab68?page=108"> between a gene variant in the MBOAT7 gene (the rs</a> <a title="AJG_Vol.113.No3 page 109" href="http://viewer.zmags.com/publication/777bab68?page=109"> 378 Umano et al. LIVER and glucose toleranc</a> <a title="AJG_Vol.113.No3 page 110" href="http://viewer.zmags.com/publication/777bab68?page=110"> stratified by ethnicity and MBOAT7 genotype Cauca</a> <a title="AJG_Vol.113.No3 page 111" href="http://viewer.zmags.com/publication/777bab68?page=111"> 380 Umano et al. a 4 3 2 Caucasian</a> <a title="AJG_Vol.113.No3 page 112" href="http://viewer.zmags.com/publication/777bab68?page=112"> MBOAT7 gene association with insulin resistance a</a> <a title="AJG_Vol.113.No3 page 113" href="http://viewer.zmags.com/publication/777bab68?page=113"> 382 Umano et al. ab </a> <a title="AJG_Vol.113.No3 page 114" href="http://viewer.zmags.com/publication/777bab68?page=114"> Study Highlights WHAT IS CURRENT KNOWLEDGE ✓ The</a> <a title="AJG_Vol.113.No3 page 115" href="http://viewer.zmags.com/publication/777bab68?page=115"> 384 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.113.No3 page 116" href="http://viewer.zmags.com/publication/777bab68?page=116"> maintenance therapy (8,9), because of a low effic</a> <a title="AJG_Vol.113.No3 page 117" href="http://viewer.zmags.com/publication/777bab68?page=117"> 386 Jeuring et al. INFLAMMATORY BOWEL DISEAS</a> <a title="AJG_Vol.113.No3 page 118" href="http://viewer.zmags.com/publication/777bab68?page=118"> Corticosteroid Use in Inflammatory Bowel Disease </a> <a title="AJG_Vol.113.No3 page 119" href="http://viewer.zmags.com/publication/777bab68?page=119"> 388 Jeuring et al. INFLAMMATORY BOWEL DISEAS</a> <a title="AJG_Vol.113.No3 page 120" href="http://viewer.zmags.com/publication/777bab68?page=120"> Corticosteroid Use in Inflammatory Bowel Disease </a> <a title="AJG_Vol.113.No3 page 121" href="http://viewer.zmags.com/publication/777bab68?page=121"> 390 Jeuring et al. INFLAMMATORY BOWEL DISEAS</a> <a title="AJG_Vol.113.No3 page 122" href="http://viewer.zmags.com/publication/777bab68?page=122"> Corticosteroid Use in Inflammatory Bowel Disease </a> <a title="AJG_Vol.113.No3 page 123" href="http://viewer.zmags.com/publication/777bab68?page=123"> 392 Jeuring et al. Crohn's disease a </a> <a title="AJG_Vol.113.No3 page 124" href="http://viewer.zmags.com/publication/777bab68?page=124"> Corticosteroid Use in Inflammatory Bowel Disease </a> <a title="AJG_Vol.113.No3 page 125" href="http://viewer.zmags.com/publication/777bab68?page=125"> 394 Jeuring et al. INFLAMMATORY BOWEL DISEAS</a> <a title="AJG_Vol.113.No3 page 126" href="http://viewer.zmags.com/publication/777bab68?page=126"> 3. Truelove SC, Witts LJ. Cortisone in ulcerativ</a> <a title="AJG_Vol.113.No3 page 127" href="http://viewer.zmags.com/publication/777bab68?page=127"> 396 ORIGINAL CONTRIBUTIONS see related e</a> <a title="AJG_Vol.113.No3 page 128" href="http://viewer.zmags.com/publication/777bab68?page=128"> Long-Term Safety of Anti-TNF Drugs During Pregnan</a> <a title="AJG_Vol.113.No3 page 129" href="http://viewer.zmags.com/publication/777bab68?page=129"> 398 Chaparro et al. mittees of each parti</a> <a title="AJG_Vol.113.No3 page 130" href="http://viewer.zmags.com/publication/777bab68?page=130"> Table 1. Demographic characteristics of the mothe</a> <a title="AJG_Vol.113.No3 page 131" href="http://viewer.zmags.com/publication/777bab68?page=131"> Log-rank>0.05 400 Chaparro et al. 100% </a> <a title="AJG_Vol.113.No3 page 132" href="http://viewer.zmags.com/publication/777bab68?page=132"> Table 5. Factors associated with the risk of seve</a> <a title="AJG_Vol.113.No3 page 133" href="http://viewer.zmags.com/publication/777bab68?page=133"> 402 Chaparro et al. INFLAMMATORY BOWEL DISEA</a> <a title="AJG_Vol.113.No3 page 134" href="http://viewer.zmags.com/publication/777bab68?page=134"> Takeda; consultant for MSD and Takeda, and has re</a> <a title="AJG_Vol.113.No3 page 135" href="http://viewer.zmags.com/publication/777bab68?page=135"> 404 CONTINUING MEDICAL EDUCATION CME CON</a> <a title="AJG_Vol.113.No3 page 136" href="http://viewer.zmags.com/publication/777bab68?page=136"> ORIGINAL CONTRIBUTIONS 405 see related ed</a> <a title="AJG_Vol.113.No3 page 137" href="http://viewer.zmags.com/publication/777bab68?page=137"> 406 Lewis et al. INFLAMMATORY BOWEL DISEASE </a> <a title="AJG_Vol.113.No3 page 138" href="http://viewer.zmags.com/publication/777bab68?page=138"> Follow-up period Follow-up began on the index dat</a> <a title="AJG_Vol.113.No3 page 139" href="http://viewer.zmags.com/publication/777bab68?page=139"> 408 Lewis et al. 2 dispensings of adalimu</a> <a title="AJG_Vol.113.No3 page 140" href="http://viewer.zmags.com/publication/777bab68?page=140"> Risk of Mortality With IBD Therapies 409 P</a> <a title="AJG_Vol.113.No3 page 141" href="http://viewer.zmags.com/publication/777bab68?page=141"> 410 Lewis et al. INFLAMMATORY BOWEL DISEASE </a> <a title="AJG_Vol.113.No3 page 142" href="http://viewer.zmags.com/publication/777bab68?page=142"> Risk of Mortality With IBD Therapies 411 Ta</a> <a title="AJG_Vol.113.No3 page 143" href="http://viewer.zmags.com/publication/777bab68?page=143"> 412 Lewis et al. INFLAMMATORY BOWEL DISEASE </a> <a title="AJG_Vol.113.No3 page 144" href="http://viewer.zmags.com/publication/777bab68?page=144"> Risk of Mortality With IBD Therapies 413 a</a> <a title="AJG_Vol.113.No3 page 145" href="http://viewer.zmags.com/publication/777bab68?page=145"> 414 Lewis et al. Model 1 INFLAMMATORY </a> <a title="AJG_Vol.113.No3 page 146" href="http://viewer.zmags.com/publication/777bab68?page=146"> have a meaningful response to therapy and would b</a> <a title="AJG_Vol.113.No3 page 147" href="http://viewer.zmags.com/publication/777bab68?page=147"> 416 Lewis et al. INFLAMMATORY BOWEL DISEASE </a> <a title="AJG_Vol.113.No3 page 148" href="http://viewer.zmags.com/publication/777bab68?page=148"> 34. Lichtenstein GR, Feagan BG, Cohen RD et al. S</a> <a title="AJG_Vol.113.No3 page 149" href="http://viewer.zmags.com/publication/777bab68?page=149"> 418 EDITORIAL see related article on pag</a> <a title="AJG_Vol.113.No3 page 150" href="http://viewer.zmags.com/publication/777bab68?page=150"> In this journal Lewis et al. used Medicaid dat</a> <a title="AJG_Vol.113.No3 page 151" href="http://viewer.zmags.com/publication/777bab68?page=151"> 420 Bernstein INFLAMMATORY BOWEL DISEASE 4.</a> <a title="AJG_Vol.113.No3 page 152" href="http://viewer.zmags.com/publication/777bab68?page=152"> ORIGINAL CONTRIBUTIONS 421 see related edi</a> <a title="AJG_Vol.113.No3 page 153" href="http://viewer.zmags.com/publication/777bab68?page=153"> 422 Francavilla et al. COLON/SMALL BOWEL (8</a> <a title="AJG_Vol.113.No3 page 154" href="http://viewer.zmags.com/publication/777bab68?page=154"> Non-Celiac Gluten Sensitivity in Children 423 </a> <a title="AJG_Vol.113.No3 page 155" href="http://viewer.zmags.com/publication/777bab68?page=155"> Patients entering the running-in (n = 36) Pa</a> <a title="AJG_Vol.113.No3 page 156" href="http://viewer.zmags.com/publication/777bab68?page=156"> Table 1. Baseline demographic and clinical charac</a> <a title="AJG_Vol.113.No3 page 157" href="http://viewer.zmags.com/publication/777bab68?page=157"> 426 Francavilla et al. COLON/SMALL BOWEL Ta</a> <a title="AJG_Vol.113.No3 page 158" href="http://viewer.zmags.com/publication/777bab68?page=158"> Non-Celiac Gluten Sensitivity in Children 427 </a> <a title="AJG_Vol.113.No3 page 159" href="http://viewer.zmags.com/publication/777bab68?page=159"> 428 Francavilla et al. ab 800 10.0 9.07</a> <a title="AJG_Vol.113.No3 page 160" href="http://viewer.zmags.com/publication/777bab68?page=160"> diet; this figure is not alarming if we consider </a> <a title="AJG_Vol.113.No3 page 161" href="http://viewer.zmags.com/publication/777bab68?page=161"> 430 Francavilla et al. COLON/SMALL BOWEL 15</a> <a title="AJG_Vol.113.No3 page 162" href="http://viewer.zmags.com/publication/777bab68?page=162"> ORIGINAL CONTRIBUTIONS 431 see related ed</a> <a title="AJG_Vol.113.No3 page 163" href="http://viewer.zmags.com/publication/777bab68?page=163"> 432 Gourevitch et al. COLON/SMALL BOWEL one</a> <a title="AJG_Vol.113.No3 page 164" href="http://viewer.zmags.com/publication/777bab68?page=164"> flexure, 35–50 cm from anal verge); and rectosigm</a> <a title="AJG_Vol.113.No3 page 165" href="http://viewer.zmags.com/publication/777bab68?page=165"> 434 Gourevitch et al. were considered “Ga</a> <a title="AJG_Vol.113.No3 page 166" href="http://viewer.zmags.com/publication/777bab68?page=166"> Table 2. Characteristics of pathologists (n=48) </a> <a title="AJG_Vol.113.No3 page 167" href="http://viewer.zmags.com/publication/777bab68?page=167"> 436 Gourevitch et al. </a> <a title="AJG_Vol.113.No3 page 168" href="http://viewer.zmags.com/publication/777bab68?page=168"> There are several explanations for why there i</a> <a title="AJG_Vol.113.No3 page 169" href="http://viewer.zmags.com/publication/777bab68?page=169"> 438 Gourevitch et al. COLON/SMALL BOWEL of </a> <a title="AJG_Vol.113.No3 page 170" href="http://viewer.zmags.com/publication/777bab68?page=170"> 36. Bucholz EM, Butala NM, Ma S et al. Life expec</a> <a title="AJG_Vol.113.No3 page 171" href="http://viewer.zmags.com/publication/777bab68?page=171"> 440 LETTERS TO THE EDITOR The North Ame</a> <a title="AJG_Vol.113.No3 page 172" href="http://viewer.zmags.com/publication/777bab68?page=172"> provides objective evidence of reduced fructose a</a> <a title="AJG_Vol.113.No3 page 173" href="http://viewer.zmags.com/publication/777bab68?page=173"> 442 Letters to the Editor severity of stea</a> <a title="AJG_Vol.113.No3 page 174" href="http://viewer.zmags.com/publication/777bab68?page=174"> Benefit of Treatment With Sebelipase-Alfa in a 63-</a> <a title="AJG_Vol.113.No3 page 175" href="http://viewer.zmags.com/publication/777bab68?page=175"> 444 Letters to the Editor ab 200</a> <a title="AJG_Vol.113.No3 page 176" href="http://viewer.zmags.com/publication/777bab68?page=176"> Letters to the Editor 445 Table 1. Course o</a> <a title="AJG_Vol.113.No3 page 177" href="http://viewer.zmags.com/publication/777bab68?page=177"> 446 ANNOUNCEMENTS CALENDAR OF COURSES, </a> <a title="AJG_Vol.113.No3 page 178" href="http://viewer.zmags.com/publication/777bab68?page=178"> ERRATA, CORRIGENDA AND RETRACTIONS 447 Corri</a> <a title="AJG_Vol.113.No3 page 179" href="http://viewer.zmags.com/publication/777bab68?page=179"> The flagship journal of the American College of Ga</a> <a title="AJG_Vol.113.No3 page 180" href="http://viewer.zmags.com/publication/777bab68?page=180"> Accessible. Relevant. Practical. The information</a> <a title="AJG_Vol.113.No3 page 181" href="http://viewer.zmags.com/publication/777bab68?page=181"> CLASSIFIEDS Physician-Led Medicine in Montana Ga</a> <a title="AJG_Vol.113.No3 page 182" href="http://viewer.zmags.com/publication/777bab68?page=182"> GASTROENTEROLOGY CLINICIAN EDUCATOR The Division</a> <a title="AJG_Vol.113.No3 page 183" href="http://viewer.zmags.com/publication/777bab68?page=183"> Western Wisconsin Health is seeking a fulltime Ga</a> <a title="AJG_Vol.113.No3 page 184" href="http://viewer.zmags.com/publication/777bab68?page=184"> IMPORTANT SAFETY INFORMATION SUPREP® Bowel Prep K</a> <a title="AJG_Vol.113.No3 page 185" href="http://viewer.zmags.com/publication/777bab68?page=185"> #1 MOST PRESCRIBED, BRANDED BOWEL PREP KIT1 A</a>