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<br /> ARCHIVE<br /> VOLUME 113 NUMBER 1 JANUARY 2018<br /> www.nature.com/ajg<br /> OFFICIAL PUBLICATION OF THE AMERICAN COLLEGE OF GASTROENTEROLOGY<br /> EDITORS: Brian E. Lacy, PhD, MD, FACG and Brennan Spiegel, MD, MSHS, FACG<br /> January 2018<br /> AJG_Cover-Special-issue2017_v3.indd 1 12/19/17 3:10 PM<br /> 2014 2015 2016 2017<br /> VOLUME 113 NUMBER 2 FEBRUARY 2018<br /> www.nature.com/ajg<br /> OFFICIAL PUBLICATION OF THE AMERICAN COLLEGE OF GASTROENTEROLOGY<br /> LEADING ARTICLES OF THE MONTH<br /> ACG Clinical Guideline<br /> 175 ACG Clinical Guideline: Alcoholic Liver Disease CME<br /> Ashwani K. Singal, Ramon Bataller, Joseph Ahn, Patrick S. Kamath and<br /> Vijay H. Shah<br /> Esophagus<br /> 196 Timed Barium Swallow: <a title="AJG_Vol.113.No2 page 1" href="http://viewer.zmags.com/publication/7b03a1ad?page=1"> ARCHIVE VOLUME 113 NUMBER 1 JANUARY 2018 www.na</a> <a title="AJG_Vol.113.No2 page 2" href="http://viewer.zmags.com/publication/7b03a1ad?page=2"> VOLUME 113 NUMBER 2 FEBRUARY 2018 www.nature.com/</a> <a title="AJG_Vol.113.No2 page 3" href="http://viewer.zmags.com/publication/7b03a1ad?page=3"> Help adult patients with IBS-D break free from </a> <a title="AJG_Vol.113.No2 page 4" href="http://viewer.zmags.com/publication/7b03a1ad?page=4"> BRIEF SUMMARY OF PRESCRIBING INFORMATION This Bri</a> <a title="AJG_Vol.113.No2 page 5" href="http://viewer.zmags.com/publication/7b03a1ad?page=5"> www.nature.com/ajg The American Journal o</a> <a title="AJG_Vol.113.No2 page 6" href="http://viewer.zmags.com/publication/7b03a1ad?page=6"> RECOMMEND THE BEST WITH NEXIUM® 24HR Nexium® 24HR</a> <a title="AJG_Vol.113.No2 page 7" href="http://viewer.zmags.com/publication/7b03a1ad?page=7"> official publication of the american college</a> <a title="AJG_Vol.113.No2 page 8" href="http://viewer.zmags.com/publication/7b03a1ad?page=8"> 65 Years of GI Endoscopy Innovation in One Powerf</a> <a title="AJG_Vol.113.No2 page 9" href="http://viewer.zmags.com/publication/7b03a1ad?page=9"> Attend an upcoming 2018 ACG POSTGRADUATE COURS</a> <a title="AJG_Vol.113.No2 page 10" href="http://viewer.zmags.com/publication/7b03a1ad?page=10"> For GI Endoscopic Resections Visit eleviewUS.com </a> <a title="AJG_Vol.113.No2 page 11" href="http://viewer.zmags.com/publication/7b03a1ad?page=11"> SUBMIT YOUR APPLICATION for the ACG 2018 Internat</a> <a title="AJG_Vol.113.No2 page 12" href="http://viewer.zmags.com/publication/7b03a1ad?page=12"> In adults with Clostridium difficile –associated d</a> <a title="AJG_Vol.113.No2 page 13" href="http://viewer.zmags.com/publication/7b03a1ad?page=13"> DIFICID: Comparable initial clinical response rat</a> <a title="AJG_Vol.113.No2 page 14" href="http://viewer.zmags.com/publication/7b03a1ad?page=14"> In the same studies, DIFICID demonstrated superio</a> <a title="AJG_Vol.113.No2 page 15" href="http://viewer.zmags.com/publication/7b03a1ad?page=15"> BRIEF SUMMARY OF PRESCRIBING INFORMATION DIFICID </a> <a title="AJG_Vol.113.No2 page 16" href="http://viewer.zmags.com/publication/7b03a1ad?page=16"> e week's best science, from the world's #1 s</a> <a title="AJG_Vol.113.No2 page 17" href="http://viewer.zmags.com/publication/7b03a1ad?page=17"> For first-line constipation therapy, stick with t</a> <a title="AJG_Vol.113.No2 page 18" href="http://viewer.zmags.com/publication/7b03a1ad?page=18"> High-definition colonoscopy image showing a sessil</a> <a title="AJG_Vol.113.No2 page 19" href="http://viewer.zmags.com/publication/7b03a1ad?page=19"> CONTENTS </a> <a title="AJG_Vol.113.No2 page 20" href="http://viewer.zmags.com/publication/7b03a1ad?page=20"> www.nature.com/ajg </a> <a title="AJG_Vol.113.No2 page 21" href="http://viewer.zmags.com/publication/7b03a1ad?page=21"> The flagship journal of the American College of Ga</a> <a title="AJG_Vol.113.No2 page 22" href="http://viewer.zmags.com/publication/7b03a1ad?page=22"> Sofosbuvir-based therapy changed expectations in </a> <a title="AJG_Vol.113.No2 page 23" href="http://viewer.zmags.com/publication/7b03a1ad?page=23"> FOR TREATING CHRONIC HCV GT 1 BE THE ONE WHO </a> <a title="AJG_Vol.113.No2 page 24" href="http://viewer.zmags.com/publication/7b03a1ad?page=24"> FOR TREATING CHRONIC HCV EXPAND WHAT'S POSSIBL</a> <a title="AJG_Vol.113.No2 page 25" href="http://viewer.zmags.com/publication/7b03a1ad?page=25"> HARVONI® (ledipasvir 90 mg and sofosbuvir 400 mg)</a> <a title="AJG_Vol.113.No2 page 26" href="http://viewer.zmags.com/publication/7b03a1ad?page=26"> Brief Summary (cont.) •Laboratory Abnormalities</a> <a title="AJG_Vol.113.No2 page 27" href="http://viewer.zmags.com/publication/7b03a1ad?page=27"> EPCLUSA® (sofosbuvir 400 mg and velpatasvir 100 m</a> <a title="AJG_Vol.113.No2 page 28" href="http://viewer.zmags.com/publication/7b03a1ad?page=28"> Brief Summary (cont.) In ASTRAL-1, isolated, asym</a> <a title="AJG_Vol.113.No2 page 29" href="http://viewer.zmags.com/publication/7b03a1ad?page=29"> RENFLEXIS TM (infliximab-abda) The in iximab </a> <a title="AJG_Vol.113.No2 page 30" href="http://viewer.zmags.com/publication/7b03a1ad?page=30"> FDA-approved as a biosimilar to Remicade® (in ixi</a> <a title="AJG_Vol.113.No2 page 31" href="http://viewer.zmags.com/publication/7b03a1ad?page=31"> Brief Summary of the Prescribing Information for </a> <a title="AJG_Vol.113.No2 page 32" href="http://viewer.zmags.com/publication/7b03a1ad?page=32"> Brief Summary of the Prescribing Information for </a> <a title="AJG_Vol.113.No2 page 33" href="http://viewer.zmags.com/publication/7b03a1ad?page=33"> Brief Summary of the Prescribing Information for </a> <a title="AJG_Vol.113.No2 page 34" href="http://viewer.zmags.com/publication/7b03a1ad?page=34"> Brief Summary of the Prescribing Information for </a> <a title="AJG_Vol.113.No2 page 35" href="http://viewer.zmags.com/publication/7b03a1ad?page=35"> FATTY LIVER DISEASE Free online </a> <a title="AJG_Vol.113.No2 page 36" href="http://viewer.zmags.com/publication/7b03a1ad?page=36"> IMPORTANT SAFETY INFORMATION SUPREP® Bowel Prep K</a> <a title="AJG_Vol.113.No2 page 37" href="http://viewer.zmags.com/publication/7b03a1ad?page=37"> #1 MOST PRESCRIBED, BRANDED BOWEL PREP KIT1 </a> <a title="AJG_Vol.113.No2 page 38" href="http://viewer.zmags.com/publication/7b03a1ad?page=38"> THE RED SECTION 157 see related editorial</a> <a title="AJG_Vol.113.No2 page 39" href="http://viewer.zmags.com/publication/7b03a1ad?page=39"> 158 THE RED SECTION applying for a researc</a> <a title="AJG_Vol.113.No2 page 40" href="http://viewer.zmags.com/publication/7b03a1ad?page=40"> Public Policy Council; Brad Conway, ACG Vice Pres</a> <a title="AJG_Vol.113.No2 page 41" href="http://viewer.zmags.com/publication/7b03a1ad?page=41"> 160 THE RED SECTION areas of gastroenterol</a> <a title="AJG_Vol.113.No2 page 42" href="http://viewer.zmags.com/publication/7b03a1ad?page=42"> THE RED SECTION 161 see related editorial</a> <a title="AJG_Vol.113.No2 page 43" href="http://viewer.zmags.com/publication/7b03a1ad?page=43"> 162 THE RED SECTION HOW I APPROACH IT Roux-e</a> <a title="AJG_Vol.113.No2 page 44" href="http://viewer.zmags.com/publication/7b03a1ad?page=44"> Abdominal pain in RYGB* – Physical exam </a> <a title="AJG_Vol.113.No2 page 45" href="http://viewer.zmags.com/publication/7b03a1ad?page=45"> 164 THE RED SECTION HOW I APPROACH IT Table </a> <a title="AJG_Vol.113.No2 page 46" href="http://viewer.zmags.com/publication/7b03a1ad?page=46"> THE RED SECTION 165 ab Figure </a> <a title="AJG_Vol.113.No2 page 47" href="http://viewer.zmags.com/publication/7b03a1ad?page=47"> 166 THE RED SECTION HOW I APPROACH IT Figure</a> <a title="AJG_Vol.113.No2 page 48" href="http://viewer.zmags.com/publication/7b03a1ad?page=48"> THE RED SECTION 167 see related editorial</a> <a title="AJG_Vol.113.No2 page 49" href="http://viewer.zmags.com/publication/7b03a1ad?page=49"> 168 THE RED SECTION QUALITY MATTERS Table 1.</a> <a title="AJG_Vol.113.No2 page 50" href="http://viewer.zmags.com/publication/7b03a1ad?page=50"> REFERENCES 1. http://www.npr.org/sections/goatsa</a> <a title="AJG_Vol.113.No2 page 51" href="http://viewer.zmags.com/publication/7b03a1ad?page=51"> 170 THE RED SECTION VIEW FROM THE HILL Inter</a> <a title="AJG_Vol.113.No2 page 52" href="http://viewer.zmags.com/publication/7b03a1ad?page=52"> Sharing of financial risk serves as a “clear and </a> <a title="AJG_Vol.113.No2 page 53" href="http://viewer.zmags.com/publication/7b03a1ad?page=53"> 172 THE RED SECTION Images of the Month R</a> <a title="AJG_Vol.113.No2 page 54" href="http://viewer.zmags.com/publication/7b03a1ad?page=54"> Springer Nature </a> <a title="AJG_Vol.113.No2 page 55" href="http://viewer.zmags.com/publication/7b03a1ad?page=55"> 174 THE RED SECTION Video of the Month A C</a> <a title="AJG_Vol.113.No2 page 56" href="http://viewer.zmags.com/publication/7b03a1ad?page=56"> CLINICAL GUIDELINES 175 CME ACG Clinical </a> <a title="AJG_Vol.113.No2 page 57" href="http://viewer.zmags.com/publication/7b03a1ad?page=57"> 176 Singal et al. Table 1. Recommendations</a> <a title="AJG_Vol.113.No2 page 58" href="http://viewer.zmags.com/publication/7b03a1ad?page=58"> Alcoholic Liver Disease 177 Table 2. Key co</a> <a title="AJG_Vol.113.No2 page 59" href="http://viewer.zmags.com/publication/7b03a1ad?page=59"> 178 Singal et al. environments, especiall</a> <a title="AJG_Vol.113.No2 page 60" href="http://viewer.zmags.com/publication/7b03a1ad?page=60"> Alcoholic hepatitis Chronic alcohol </a> <a title="AJG_Vol.113.No2 page 61" href="http://viewer.zmags.com/publication/7b03a1ad?page=61"> 180 Singal et al. inflammation/damage or </a> <a title="AJG_Vol.113.No2 page 62" href="http://viewer.zmags.com/publication/7b03a1ad?page=62"> glucuronide in hair samples can detect alcohol us</a> <a title="AJG_Vol.113.No2 page 63" href="http://viewer.zmags.com/publication/7b03a1ad?page=63"> 182 Singal et al. Management of alcohol w</a> <a title="AJG_Vol.113.No2 page 64" href="http://viewer.zmags.com/publication/7b03a1ad?page=64"> Alcoholic Liver Disease 183 Table 3. Propos</a> <a title="AJG_Vol.113.No2 page 65" href="http://viewer.zmags.com/publication/7b03a1ad?page=65"> 184 Singal et al. INITIAL EVALUATION FIN</a> <a title="AJG_Vol.113.No2 page 66" href="http://viewer.zmags.com/publication/7b03a1ad?page=66"> Alcoholic Liver Disease 185 </a> <a title="AJG_Vol.113.No2 page 67" href="http://viewer.zmags.com/publication/7b03a1ad?page=67"> 186 Singal et al. Table 4. Specific pharmac</a> <a title="AJG_Vol.113.No2 page 68" href="http://viewer.zmags.com/publication/7b03a1ad?page=68"> and durations of corticosteroid therapy. Response</a> <a title="AJG_Vol.113.No2 page 69" href="http://viewer.zmags.com/publication/7b03a1ad?page=69"> 188 Singal et al. LIVER TRANSPLANTATION I</a> <a title="AJG_Vol.113.No2 page 70" href="http://viewer.zmags.com/publication/7b03a1ad?page=70"> The limited data comparing outcomes of patient</a> <a title="AJG_Vol.113.No2 page 71" href="http://viewer.zmags.com/publication/7b03a1ad?page=71"> 190 Singal et al. responding to medical t</a> <a title="AJG_Vol.113.No2 page 72" href="http://viewer.zmags.com/publication/7b03a1ad?page=72"> 13. Gao B, Bataller R. Alcoholic liver disease: </a> <a title="AJG_Vol.113.No2 page 73" href="http://viewer.zmags.com/publication/7b03a1ad?page=73"> 192 Singal et al. 65. Louvet A, Labreuche</a> <a title="AJG_Vol.113.No2 page 74" href="http://viewer.zmags.com/publication/7b03a1ad?page=74"> 116. Park SH, Kim DJ, Kim YS et al. Pentoxifyllin</a> <a title="AJG_Vol.113.No2 page 75" href="http://viewer.zmags.com/publication/7b03a1ad?page=75"> 194 Singal et al. 169. Faure S, Herrero A</a> <a title="AJG_Vol.113.No2 page 76" href="http://viewer.zmags.com/publication/7b03a1ad?page=76"> CONTINUING MEDICAL EDUCATION 195 CME Con</a> <a title="AJG_Vol.113.No2 page 77" href="http://viewer.zmags.com/publication/7b03a1ad?page=77"> 196 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.113.No2 page 78" href="http://viewer.zmags.com/publication/7b03a1ad?page=78"> follow-up (3). Following pneumatic dilations, a g</a> <a title="AJG_Vol.113.No2 page 79" href="http://viewer.zmags.com/publication/7b03a1ad?page=79"> 198 Blonski et al. ESOPHAGUS High-resolutio</a> <a title="AJG_Vol.113.No2 page 80" href="http://viewer.zmags.com/publication/7b03a1ad?page=80"> Table 1. Overall predictive accuracy of barium he</a> <a title="AJG_Vol.113.No2 page 81" href="http://viewer.zmags.com/publication/7b03a1ad?page=81"> 200 Blonski et al. a 1.0 0.8 ESOPHAG</a> <a title="AJG_Vol.113.No2 page 82" href="http://viewer.zmags.com/publication/7b03a1ad?page=82"> Timed Barium Swallow 201 Table 3. Final dia</a> <a title="AJG_Vol.113.No2 page 83" href="http://viewer.zmags.com/publication/7b03a1ad?page=83"> 202 Blonski et al. ESOPHAGUS of eight patie</a> <a title="AJG_Vol.113.No2 page 84" href="http://viewer.zmags.com/publication/7b03a1ad?page=84"> 5. Bredenoord AJ, Fox M, Kahrilas PJ et al. Chic</a> <a title="AJG_Vol.113.No2 page 85" href="http://viewer.zmags.com/publication/7b03a1ad?page=85"> 204 CONTINUING MEDICAL EDUCATION CME CON</a> <a title="AJG_Vol.113.No2 page 86" href="http://viewer.zmags.com/publication/7b03a1ad?page=86"> ORIGINAL CONTRIBUTIONS 205 see related ed</a> <a title="AJG_Vol.113.No2 page 87" href="http://viewer.zmags.com/publication/7b03a1ad?page=87"> 206 Wu et al. ESOPHAGUS Functional lum</a> <a title="AJG_Vol.113.No2 page 88" href="http://viewer.zmags.com/publication/7b03a1ad?page=88"> Novel Intra-Procedural Distensibility Measurement</a> <a title="AJG_Vol.113.No2 page 89" href="http://viewer.zmags.com/publication/7b03a1ad?page=89"> 208 Wu et al. ESOPHAGUS Symptom assessment </a> <a title="AJG_Vol.113.No2 page 90" href="http://viewer.zmags.com/publication/7b03a1ad?page=90"> Novel Intra-Procedural Distensibility Measurement</a> <a title="AJG_Vol.113.No2 page 91" href="http://viewer.zmags.com/publication/7b03a1ad?page=91"> 210 Wu et al. 0 –2 –4 –6 –8 P</a> <a title="AJG_Vol.113.No2 page 92" href="http://viewer.zmags.com/publication/7b03a1ad?page=92"> subgroup analysis of patients with low baseline E</a> <a title="AJG_Vol.113.No2 page 93" href="http://viewer.zmags.com/publication/7b03a1ad?page=93"> 212 Wu et al. ESOPHAGUS Study Highlights W</a> <a title="AJG_Vol.113.No2 page 94" href="http://viewer.zmags.com/publication/7b03a1ad?page=94"> EDITORIAL 213 see related articles on pag</a> <a title="AJG_Vol.113.No2 page 95" href="http://viewer.zmags.com/publication/7b03a1ad?page=95"> 214 Triggs and Kahrilas ESOPHAGUS respectiv</a> <a title="AJG_Vol.113.No2 page 96" href="http://viewer.zmags.com/publication/7b03a1ad?page=96"> 7. Scherer JR, Kwiatek MA, Soper NJ et al. Funct</a> <a title="AJG_Vol.113.No2 page 97" href="http://viewer.zmags.com/publication/7b03a1ad?page=97"> 216 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.113.No2 page 98" href="http://viewer.zmags.com/publication/7b03a1ad?page=98"> FD patients (12–14). Some studies demonstrate tha</a> <a title="AJG_Vol.113.No2 page 99" href="http://viewer.zmags.com/publication/7b03a1ad?page=99"> 218 Lacy et al. I.V. 10 mCi99mTcO4– STOM</a> <a title="AJG_Vol.113.No2 page 100" href="http://viewer.zmags.com/publication/7b03a1ad?page=100"> Table 1. Patient characteristics PLA n=97 A</a> <a title="AJG_Vol.113.No2 page 101" href="http://viewer.zmags.com/publication/7b03a1ad?page=101"> 220 Lacy et al. 140 129.8 120 STOMACH</a> <a title="AJG_Vol.113.No2 page 102" href="http://viewer.zmags.com/publication/7b03a1ad?page=102"> Antidepressants and Gastric Emptying in FD Patien</a> <a title="AJG_Vol.113.No2 page 103" href="http://viewer.zmags.com/publication/7b03a1ad?page=103"> 222 Lacy et al. STOMACH % 90 80 70 60 50 40</a> <a title="AJG_Vol.113.No2 page 104" href="http://viewer.zmags.com/publication/7b03a1ad?page=104"> affect post-prandial (fed) volume. The disparate </a> <a title="AJG_Vol.113.No2 page 105" href="http://viewer.zmags.com/publication/7b03a1ad?page=105"> 224 Lacy et al. STOMACH 11. Talley NJ, Walk</a> <a title="AJG_Vol.113.No2 page 106" href="http://viewer.zmags.com/publication/7b03a1ad?page=106"> ORIGINAL CONTRIBUTIONS 225 see related edi</a> <a title="AJG_Vol.113.No2 page 107" href="http://viewer.zmags.com/publication/7b03a1ad?page=107"> 226 Iacucci et al. ENDOSCOPY historically b</a> <a title="AJG_Vol.113.No2 page 108" href="http://viewer.zmags.com/publication/7b03a1ad?page=108"> A Randomized Trial Comparing High Definition Colo</a> <a title="AJG_Vol.113.No2 page 109" href="http://viewer.zmags.com/publication/7b03a1ad?page=109"> 228 Iacucci et al. ENDOSCOPY HD Group N</a> <a title="AJG_Vol.113.No2 page 110" href="http://viewer.zmags.com/publication/7b03a1ad?page=110"> A Randomized Trial Comparing High Definition Colo</a> <a title="AJG_Vol.113.No2 page 111" href="http://viewer.zmags.com/publication/7b03a1ad?page=111"> 230 Iacucci et al. ENDOSCOPY Figure 3. Non </a> <a title="AJG_Vol.113.No2 page 112" href="http://viewer.zmags.com/publication/7b03a1ad?page=112"> Table 4. Univariate analysis: endoscopic findings </a> <a title="AJG_Vol.113.No2 page 113" href="http://viewer.zmags.com/publication/7b03a1ad?page=113"> 232 Iacucci et al. ENDOSCOPY panelists had </a> <a title="AJG_Vol.113.No2 page 114" href="http://viewer.zmags.com/publication/7b03a1ad?page=114"> CONFLICT OF INTEREST Guarantor of the article: Ma</a> <a title="AJG_Vol.113.No2 page 115" href="http://viewer.zmags.com/publication/7b03a1ad?page=115"> 234 Iacucci et al. dysplasia in lon</a> <a title="AJG_Vol.113.No2 page 116" href="http://viewer.zmags.com/publication/7b03a1ad?page=116"> ORIGINAL CONTRIBUTIONS 235 see related edi</a> <a title="AJG_Vol.113.No2 page 117" href="http://viewer.zmags.com/publication/7b03a1ad?page=117"> 236 Lai et al. LIVER disease or physiologic</a> <a title="AJG_Vol.113.No2 page 118" href="http://viewer.zmags.com/publication/7b03a1ad?page=118"> The primary outcome was waitlist mortality, wh</a> <a title="AJG_Vol.113.No2 page 119" href="http://viewer.zmags.com/publication/7b03a1ad?page=119"> 238 Lai et al. LIVER Table 1. Characteristi</a> <a title="AJG_Vol.113.No2 page 120" href="http://viewer.zmags.com/publication/7b03a1ad?page=120"> The Liver Frailty Index and The Clinician Assessm</a> <a title="AJG_Vol.113.No2 page 121" href="http://viewer.zmags.com/publication/7b03a1ad?page=121"> 240 Lai et al. LIVER Table 3. Multivariable</a> <a title="AJG_Vol.113.No2 page 122" href="http://viewer.zmags.com/publication/7b03a1ad?page=122"> Our choice of the subjective clinician assessm</a> <a title="AJG_Vol.113.No2 page 123" href="http://viewer.zmags.com/publication/7b03a1ad?page=123"> 242 Lai et al. LIVER REFERENCES 1. Lai JC,</a> <a title="AJG_Vol.113.No2 page 124" href="http://viewer.zmags.com/publication/7b03a1ad?page=124"> ORIGINAL CONTRIBUTIONS 243 see related ed</a> <a title="AJG_Vol.113.No2 page 125" href="http://viewer.zmags.com/publication/7b03a1ad?page=125"> 244 Wen et al. LIVER inpatient information </a> <a title="AJG_Vol.113.No2 page 126" href="http://viewer.zmags.com/publication/7b03a1ad?page=126"> Disparities in AIH Hospitalizations 245 Tab</a> <a title="AJG_Vol.113.No2 page 127" href="http://viewer.zmags.com/publication/7b03a1ad?page=127"> 246 Wen et al. to evaluate the relationsh</a> <a title="AJG_Vol.113.No2 page 128" href="http://viewer.zmags.com/publication/7b03a1ad?page=128"> Disparities in AIH Hospitalizations 247 Tab</a> <a title="AJG_Vol.113.No2 page 129" href="http://viewer.zmags.com/publication/7b03a1ad?page=129"> 248 Wen et al. LIVER an AIH discharge diagn</a> <a title="AJG_Vol.113.No2 page 130" href="http://viewer.zmags.com/publication/7b03a1ad?page=130"> reported 3.0 cases per 100,000 (refs 21,22). By c</a> <a title="AJG_Vol.113.No2 page 131" href="http://viewer.zmags.com/publication/7b03a1ad?page=131"> 250 Wen et al. LIVER Table 5. Predictors of</a> <a title="AJG_Vol.113.No2 page 132" href="http://viewer.zmags.com/publication/7b03a1ad?page=132"> Disparities in AIH Hospitalizations 251 </a> <a title="AJG_Vol.113.No2 page 133" href="http://viewer.zmags.com/publication/7b03a1ad?page=133"> 252 Wen et al. LIVER Table 6. Predictors of</a> <a title="AJG_Vol.113.No2 page 134" href="http://viewer.zmags.com/publication/7b03a1ad?page=134"> 11. Houchens R, Ross D, Elixhauser A et al. Natio</a> <a title="AJG_Vol.113.No2 page 135" href="http://viewer.zmags.com/publication/7b03a1ad?page=135"> 254 ORIGINAL CONTRIBUTIONS see related e</a> <a title="AJG_Vol.113.No2 page 136" href="http://viewer.zmags.com/publication/7b03a1ad?page=136"> INTRODUCTION Primary biliary cholangitis (PBC) is</a> <a title="AJG_Vol.113.No2 page 137" href="http://viewer.zmags.com/publication/7b03a1ad?page=137"> 256 Harms et al. LIVER lopathy. Patients wi</a> <a title="AJG_Vol.113.No2 page 138" href="http://viewer.zmags.com/publication/7b03a1ad?page=138"> Table 1. Baseline cohort characteristics N=3,224 </a> <a title="AJG_Vol.113.No2 page 139" href="http://viewer.zmags.com/publication/7b03a1ad?page=139"> 258 Harms et al. LIVER Table 2. Covariates </a> <a title="AJG_Vol.113.No2 page 140" href="http://viewer.zmags.com/publication/7b03a1ad?page=140"> a </a> <a title="AJG_Vol.113.No2 page 141" href="http://viewer.zmags.com/publication/7b03a1ad?page=141"> 260 Harms et al. LIVER and widespread prima</a> <a title="AJG_Vol.113.No2 page 142" href="http://viewer.zmags.com/publication/7b03a1ad?page=142"> Major Hepatic Complications in Patients With PBC </a> <a title="AJG_Vol.113.No2 page 143" href="http://viewer.zmags.com/publication/7b03a1ad?page=143"> 262 Harms et al. LIVER survival and could b</a> <a title="AJG_Vol.113.No2 page 144" href="http://viewer.zmags.com/publication/7b03a1ad?page=144"> and Novartis. H.R. van Buuren is a consultant for</a> <a title="AJG_Vol.113.No2 page 145" href="http://viewer.zmags.com/publication/7b03a1ad?page=145"> 264 Harms et al. LIVER 38. Cardenas A, Mend</a> <a title="AJG_Vol.113.No2 page 146" href="http://viewer.zmags.com/publication/7b03a1ad?page=146"> ORIGINAL CONTRIBUTIONS 265 see related edi</a> <a title="AJG_Vol.113.No2 page 147" href="http://viewer.zmags.com/publication/7b03a1ad?page=147"> 266 Ghione et al. INFLAMMATORY BOWEL DISEASE</a> <a title="AJG_Vol.113.No2 page 148" href="http://viewer.zmags.com/publication/7b03a1ad?page=148"> regression estimates according to the formula: ex</a> <a title="AJG_Vol.113.No2 page 149" href="http://viewer.zmags.com/publication/7b03a1ad?page=149"> 268 Ghione et al. gradually rose from </a> <a title="AJG_Vol.113.No2 page 150" href="http://viewer.zmags.com/publication/7b03a1ad?page=150"> a Standardized incidence rates(events/100000) 1</a> <a title="AJG_Vol.113.No2 page 151" href="http://viewer.zmags.com/publication/7b03a1ad?page=151"> 270 Ghione et al. INFLAMMATORY BOWEL DISEASE</a> <a title="AJG_Vol.113.No2 page 152" href="http://viewer.zmags.com/publication/7b03a1ad?page=152"> Recherche Médicale (INSERM) and the Institut de V</a> <a title="AJG_Vol.113.No2 page 153" href="http://viewer.zmags.com/publication/7b03a1ad?page=153"> 272 Ghione et al. INFLAMMATORY BOWEL DISEASE</a> <a title="AJG_Vol.113.No2 page 154" href="http://viewer.zmags.com/publication/7b03a1ad?page=154"> EDITORIAL 273 see related article on page</a> <a title="AJG_Vol.113.No2 page 155" href="http://viewer.zmags.com/publication/7b03a1ad?page=155"> 274 Barnes and Kappelman INFLAMMATORY BOWEL </a> <a title="AJG_Vol.113.No2 page 156" href="http://viewer.zmags.com/publication/7b03a1ad?page=156"> of the manuscript, and both Dr. Barnes and Dr. Ka</a> <a title="AJG_Vol.113.No2 page 157" href="http://viewer.zmags.com/publication/7b03a1ad?page=157"> 276 ORIGINAL CONTRIBUTIONS see related e</a> <a title="AJG_Vol.113.No2 page 158" href="http://viewer.zmags.com/publication/7b03a1ad?page=158"> significant predictor of the development of antib</a> <a title="AJG_Vol.113.No2 page 159" href="http://viewer.zmags.com/publication/7b03a1ad?page=159"> 278 Govani et al. based on Contal and O’Q</a> <a title="AJG_Vol.113.No2 page 160" href="http://viewer.zmags.com/publication/7b03a1ad?page=160"> Optimal Threshold of Adherence for Anti-TNFs 2</a> <a title="AJG_Vol.113.No2 page 161" href="http://viewer.zmags.com/publication/7b03a1ad?page=161"> 280 Govani et al. INFLAMMATORY BOWEL DISEASE</a> <a title="AJG_Vol.113.No2 page 162" href="http://viewer.zmags.com/publication/7b03a1ad?page=162"> Table 4. Bivariate Cox-proportional hazards of ho</a> <a title="AJG_Vol.113.No2 page 163" href="http://viewer.zmags.com/publication/7b03a1ad?page=163"> 282 Govani et al. was not involved in the</a> <a title="AJG_Vol.113.No2 page 164" href="http://viewer.zmags.com/publication/7b03a1ad?page=164"> ORIGINAL CONTRIBUTIONS 283 see related ed</a> <a title="AJG_Vol.113.No2 page 165" href="http://viewer.zmags.com/publication/7b03a1ad?page=165"> 284 Takenaka et al. INFLAMMATORY BOWEL DISEA</a> <a title="AJG_Vol.113.No2 page 166" href="http://viewer.zmags.com/publication/7b03a1ad?page=166"> ab No mucosal activity </a> <a title="AJG_Vol.113.No2 page 167" href="http://viewer.zmags.com/publication/7b03a1ad?page=167"> 286 Takenaka et al. INFLAMMATORY BOWEL DISEA</a> <a title="AJG_Vol.113.No2 page 168" href="http://viewer.zmags.com/publication/7b03a1ad?page=168"> MRE for Small Bowel Endoscopic Healing in CD 2</a> <a title="AJG_Vol.113.No2 page 169" href="http://viewer.zmags.com/publication/7b03a1ad?page=169"> 288 Takenaka et al. **P<0.01 ab 1.0 </a> <a title="AJG_Vol.113.No2 page 170" href="http://viewer.zmags.com/publication/7b03a1ad?page=170"> MRE for Small Bowel Endoscopic Healing in CD 2</a> <a title="AJG_Vol.113.No2 page 171" href="http://viewer.zmags.com/publication/7b03a1ad?page=171"> 290 Takenaka et al. **P<0.01 ab 1.0 </a> <a title="AJG_Vol.113.No2 page 172" href="http://viewer.zmags.com/publication/7b03a1ad?page=172"> MRE for Small Bowel Endoscopic Healing in CD 2</a> <a title="AJG_Vol.113.No2 page 173" href="http://viewer.zmags.com/publication/7b03a1ad?page=173"> 292 Takenaka et al. a 1.0 </a> <a title="AJG_Vol.113.No2 page 174" href="http://viewer.zmags.com/publication/7b03a1ad?page=174"> SB endoscopic healing on BAE was associated wit</a> <a title="AJG_Vol.113.No2 page 175" href="http://viewer.zmags.com/publication/7b03a1ad?page=175"> 294 Takenaka et al. INFLAMMATORY BOWEL DISEA</a> <a title="AJG_Vol.113.No2 page 176" href="http://viewer.zmags.com/publication/7b03a1ad?page=176"> ORIGINAL CONTRIBUTIONS 295 see related edi</a> <a title="AJG_Vol.113.No2 page 177" href="http://viewer.zmags.com/publication/7b03a1ad?page=177"> 296 Sharifi-Rad et al. FUNCTIONAL GI DISORDE</a> <a title="AJG_Vol.113.No2 page 178" href="http://viewer.zmags.com/publication/7b03a1ad?page=178"> foot support in smaller patients were practiced i</a> <a title="AJG_Vol.113.No2 page 179" href="http://viewer.zmags.com/publication/7b03a1ad?page=179"> 298 Sharifi-Rad et al. FUNCTIONAL GI DISORDE</a> <a title="AJG_Vol.113.No2 page 180" href="http://viewer.zmags.com/publication/7b03a1ad?page=180"> group (12/45, 27.3%) compared with the controls (</a> <a title="AJG_Vol.113.No2 page 181" href="http://viewer.zmags.com/publication/7b03a1ad?page=181"> 300 Sharifi-Rad et al. GI DISORDERS FUNCTION</a> <a title="AJG_Vol.113.No2 page 182" href="http://viewer.zmags.com/publication/7b03a1ad?page=182"> motility more often, which leads to looser stool </a> <a title="AJG_Vol.113.No2 page 183" href="http://viewer.zmags.com/publication/7b03a1ad?page=183"> 302 Sharifi-Rad et al. FUNCTIONAL GI DISORDE</a> <a title="AJG_Vol.113.No2 page 184" href="http://viewer.zmags.com/publication/7b03a1ad?page=184"> ORIGINAL CONTRIBUTIONS 303 see related edi</a> <a title="AJG_Vol.113.No2 page 185" href="http://viewer.zmags.com/publication/7b03a1ad?page=185"> 304 Turner et al. COLON/SMALL BOWEL cases a</a> <a title="AJG_Vol.113.No2 page 186" href="http://viewer.zmags.com/publication/7b03a1ad?page=186"> Table 1. Colon polyps stratified by size and type </a> <a title="AJG_Vol.113.No2 page 187" href="http://viewer.zmags.com/publication/7b03a1ad?page=187"> 306 Turner et al. /SMALL BOWEL COLON fracti</a> <a title="AJG_Vol.113.No2 page 188" href="http://viewer.zmags.com/publication/7b03a1ad?page=188"> LETTERS TO THE EDITOR 307 Acid Control i</a> <a title="AJG_Vol.113.No2 page 189" href="http://viewer.zmags.com/publication/7b03a1ad?page=189"> 308 Letters to the Editor The switch to</a> <a title="AJG_Vol.113.No2 page 190" href="http://viewer.zmags.com/publication/7b03a1ad?page=190"> ANNOUNCEMENTS 309 CALENDAR OF COURSES, S</a> <a title="AJG_Vol.113.No2 page 191" href="http://viewer.zmags.com/publication/7b03a1ad?page=191"> 310 ERRATA, CORRIGENDA AND RETRACTIONS CORRIG</a> <a title="AJG_Vol.113.No2 page 192" href="http://viewer.zmags.com/publication/7b03a1ad?page=192"> Errata, Corrigenda and Retractions 311 Cor</a> <a title="AJG_Vol.113.No2 page 193" href="http://viewer.zmags.com/publication/7b03a1ad?page=193"> CLASSIFIEDS Physician-Led Medicine in Montana Ga</a> <a title="AJG_Vol.113.No2 page 194" href="http://viewer.zmags.com/publication/7b03a1ad?page=194"> GASTROENTEROLOGY CLINICIAN EDUCATOR The Division</a> <a title="AJG_Vol.113.No2 page 195" href="http://viewer.zmags.com/publication/7b03a1ad?page=195"> 2018 ACG AWARD NOMINATIONS Honor Your Colleague </a> <a title="AJG_Vol.113.No2 page 196" href="http://viewer.zmags.com/publication/7b03a1ad?page=196"> </a>