<br />
EUROPEAN MEDICAL JOURNAL<br />
ISSN 2397-6764 Vol 1.1 • January 2016 • emjreviews.com<br />
CONTENTS<br />
EDITORIAL BOARD......................................................................................................................................... 4<br />
FEATURES<br />
• HOW I TREAT: MULTIPLE SCLEROSIS.................................................................................................. 12<br />
Prof László Vécsei<br />
• DO THE GUIDELINES IN ONCOLOGY NEED TO EVOLVE?.............................................................. 15<br />
Dr Ahmad Awada et al.<br />
• DIAGNOSIS AND TREATMENT OF BLADDER CANCER: FROM ESTABLISHED PARADIGMS<br />
TO RECENT ADVANCES AND NEW PERSPECTIVES........................................................................ 16<br />
Dr Riccardo Autorino<br />
SYMPOSIUM REVIEWS<br />
• GREENLIGHT™ LASER SYST<a title="European Medical Journal 1.1 2016 page 1" href="http://viewer.zmags.com/publication/8169c6ab?page=1"> EUROPEAN MEDICAL JOURNAL ISSN 2397-6764 </a>
<a title="European Medical Journal 1.1 2016 page 2" href="http://viewer.zmags.com/publication/8169c6ab?page=2"> CONTENTS EDITORIAL BOARD.......................</a>
<a title="European Medical Journal 1.1 2016 page 3" href="http://viewer.zmags.com/publication/8169c6ab?page=3"> EUROPEAN MEDICAL JOURNAL • HORMONAL THERAPIES F</a>
<a title="European Medical Journal 1.1 2016 page 4" href="http://viewer.zmags.com/publication/8169c6ab?page=4"> Editorial Board Editor-in-Chief: Prof Markus P</a>
<a title="European Medical Journal 1.1 2016 page 5" href="http://viewer.zmags.com/publication/8169c6ab?page=5"> European Medical Journal Prof Robert Dellaval</a>
<a title="European Medical Journal 1.1 2016 page 6" href="http://viewer.zmags.com/publication/8169c6ab?page=6"> EMJ EUROPEAN MEDICAL GROUP Publis</a>
<a title="European Medical Journal 1.1 2016 page 7" href="http://viewer.zmags.com/publication/8169c6ab?page=7"> Welcome Welcome to the first edition of the Eur</a>
<a title="European Medical Journal 1.1 2016 page 8" href="http://viewer.zmags.com/publication/8169c6ab?page=8"> Ph+ CML Bosulif® (bosutinib): In the sea of choi</a>
<a title="European Medical Journal 1.1 2016 page 9" href="http://viewer.zmags.com/publication/8169c6ab?page=9"> Foreword Prof Markus Peck-Radosavljevic </a>
<a title="European Medical Journal 1.1 2016 page 10" href="http://viewer.zmags.com/publication/8169c6ab?page=10"> Subscribe for FREE! Don’t miss out on any of</a>
<a title="European Medical Journal 1.1 2016 page 11" href="http://viewer.zmags.com/publication/8169c6ab?page=11"> Review of the European Renal Association - Europe</a>
<a title="European Medical Journal 1.1 2016 page 12" href="http://viewer.zmags.com/publication/8169c6ab?page=12"> HOW I TREAT: MULTIPLE SCLEROSIS *László </a>
<a title="European Medical Journal 1.1 2016 page 13" href="http://viewer.zmags.com/publication/8169c6ab?page=13"> Table 2: 2015 RADS committee guidelines for multi</a>
<a title="European Medical Journal 1.1 2016 page 14" href="http://viewer.zmags.com/publication/8169c6ab?page=14"> 4. Treatment with the medication should be </a>
<a title="European Medical Journal 1.1 2016 page 15" href="http://viewer.zmags.com/publication/8169c6ab?page=15"> DO THE GUIDELINES IN ONCOLOGY </a>
<a title="European Medical Journal 1.1 2016 page 16" href="http://viewer.zmags.com/publication/8169c6ab?page=16"> DIAGNOSIS AND TREATMENT OF BLADDE CANCER: FROM ES</a>
<a title="European Medical Journal 1.1 2016 page 17" href="http://viewer.zmags.com/publication/8169c6ab?page=17"> Besides endoscopy, another ‘traditional’ diagnost</a>
<a title="European Medical Journal 1.1 2016 page 18" href="http://viewer.zmags.com/publication/8169c6ab?page=18"> performed to rule out metastases. Currently,</a>
<a title="European Medical Journal 1.1 2016 page 19" href="http://viewer.zmags.com/publication/8169c6ab?page=19"> and functional outcomes after robot- assisted</a>
<a title="European Medical Journal 1.1 2016 page 20" href="http://viewer.zmags.com/publication/8169c6ab?page=20"> GREENLIGHT™ LASER SYSTEM FOR DAY-CASE SURGERY </a>
<a title="European Medical Journal 1.1 2016 page 21" href="http://viewer.zmags.com/publication/8169c6ab?page=21"> recent additions to recommendations highlight</a>
<a title="European Medical Journal 1.1 2016 page 22" href="http://viewer.zmags.com/publication/8169c6ab?page=22"> Despite the fact that the GreenLight system</a>
<a title="European Medical Journal 1.1 2016 page 23" href="http://viewer.zmags.com/publication/8169c6ab?page=23"> training and bad experiences using other lasers i</a>
<a title="European Medical Journal 1.1 2016 page 24" href="http://viewer.zmags.com/publication/8169c6ab?page=24"> NEW INSIGHTS IN NOCTURNAL ENURESIS: GOING DIGI</a>
<a title="European Medical Journal 1.1 2016 page 25" href="http://viewer.zmags.com/publication/8169c6ab?page=25"> took place on 17th October 2015. World Bedwetting</a>
<a title="European Medical Journal 1.1 2016 page 26" href="http://viewer.zmags.com/publication/8169c6ab?page=26"> The app also includes a more detailed diary featu</a>
<a title="European Medical Journal 1.1 2016 page 27" href="http://viewer.zmags.com/publication/8169c6ab?page=27"> Table 1: Results of psychological tests following</a>
<a title="European Medical Journal 1.1 2016 page 28" href="http://viewer.zmags.com/publication/8169c6ab?page=28"> Nocturnal enuresis Monosym ptomatic Desmo res</a>
<a title="European Medical Journal 1.1 2016 page 29" href="http://viewer.zmags.com/publication/8169c6ab?page=29"> pathophysiology of NP will provide the basis for </a>
<a title="European Medical Journal 1.1 2016 page 30" href="http://viewer.zmags.com/publication/8169c6ab?page=30"> EDITOR’S PICK Our </a>
<a title="European Medical Journal 1.1 2016 page 31" href="http://viewer.zmags.com/publication/8169c6ab?page=31"> in immune complex diseases and/or alternativ</a>
<a title="European Medical Journal 1.1 2016 page 32" href="http://viewer.zmags.com/publication/8169c6ab?page=32"> mediated disease (driven primarily by the classic</a>
<a title="European Medical Journal 1.1 2016 page 33" href="http://viewer.zmags.com/publication/8169c6ab?page=33"> Table 1: Complement pathway-related glomerulopath</a>
<a title="European Medical Journal 1.1 2016 page 34" href="http://viewer.zmags.com/publication/8169c6ab?page=34"> kinase epsilon (DGKE), is very similar to that of</a>
<a title="European Medical Journal 1.1 2016 page 35" href="http://viewer.zmags.com/publication/8169c6ab?page=35"> patients with high levels of proteinuria and poor</a>
<a title="European Medical Journal 1.1 2016 page 36" href="http://viewer.zmags.com/publication/8169c6ab?page=36"> A recent genome-wide association study identified </a>
<a title="European Medical Journal 1.1 2016 page 37" href="http://viewer.zmags.com/publication/8169c6ab?page=37"> REFERENCES 1. Noris M, Remuzzi G. Glomerula</a>
<a title="European Medical Journal 1.1 2016 page 38" href="http://viewer.zmags.com/publication/8169c6ab?page=38"> 43. Mii A et al. Current status and issues of C1q</a>
<a title="European Medical Journal 1.1 2016 page 39" href="http://viewer.zmags.com/publication/8169c6ab?page=39"> HORMONAL THERAPIES FOR PATIENTS WITH ADVANCED PR</a>
<a title="European Medical Journal 1.1 2016 page 40" href="http://viewer.zmags.com/publication/8169c6ab?page=40"> HISTORICAL EVOLUTION OF ANDROGEN DEPRIVATION THER</a>
<a title="European Medical Journal 1.1 2016 page 41" href="http://viewer.zmags.com/publication/8169c6ab?page=41"> MEDICAL CASTRATION WITH GONADOTROPIN-RELEASING HO</a>
<a title="European Medical Journal 1.1 2016 page 42" href="http://viewer.zmags.com/publication/8169c6ab?page=42"> benefit in the bicalutamide monotherapy group</a>
<a title="European Medical Journal 1.1 2016 page 43" href="http://viewer.zmags.com/publication/8169c6ab?page=43"> increased over the study period. The Early Prosta</a>
<a title="European Medical Journal 1.1 2016 page 44" href="http://viewer.zmags.com/publication/8169c6ab?page=44"> locally advanced PCa is still unclear. The EORTC </a>
<a title="European Medical Journal 1.1 2016 page 45" href="http://viewer.zmags.com/publication/8169c6ab?page=45"> THE ROLE OF HORMONE THERAPY IN THE TREATMENT OF C</a>
<a title="European Medical Journal 1.1 2016 page 46" href="http://viewer.zmags.com/publication/8169c6ab?page=46"> causing side effects such as hypertensi</a>
<a title="European Medical Journal 1.1 2016 page 47" href="http://viewer.zmags.com/publication/8169c6ab?page=47"> first-line treatment compared with ADT alone.86,87</a>
<a title="European Medical Journal 1.1 2016 page 48" href="http://viewer.zmags.com/publication/8169c6ab?page=48"> as physical symptoms. Patients often self-report </a>
<a title="European Medical Journal 1.1 2016 page 49" href="http://viewer.zmags.com/publication/8169c6ab?page=49"> NCT00303784. https:/clinicaltrials.gov/ ct2/show</a>
<a title="European Medical Journal 1.1 2016 page 50" href="http://viewer.zmags.com/publication/8169c6ab?page=50"> hormonal therapy for prostate specific antigen on</a>
<a title="European Medical Journal 1.1 2016 page 51" href="http://viewer.zmags.com/publication/8169c6ab?page=51"> 87. Sweeney CJ et al. Chemohormonal Therapy in</a>
<a title="European Medical Journal 1.1 2016 page 52" href="http://viewer.zmags.com/publication/8169c6ab?page=52"> SUBSCRIBE FREE TO OUR YOUTUBE CHANNEL www.youtube</a>
<a title="European Medical Journal 1.1 2016 page 53" href="http://viewer.zmags.com/publication/8169c6ab?page=53"> Prev Ind Exclusive Interviews from a variety </a>
<a title="European Medical Journal 1.1 2016 page 54" href="http://viewer.zmags.com/publication/8169c6ab?page=54"> MALE LOWER URINARY TRACT SYMPTOMS: IS T</a>
<a title="European Medical Journal 1.1 2016 page 55" href="http://viewer.zmags.com/publication/8169c6ab?page=55"> treatment of male LUTS. A recent study of PDE5 di</a>
<a title="European Medical Journal 1.1 2016 page 56" href="http://viewer.zmags.com/publication/8169c6ab?page=56"> with alpha-blockers (AB) and 5-alpha-reductas</a>
<a title="European Medical Journal 1.1 2016 page 57" href="http://viewer.zmags.com/publication/8169c6ab?page=57"> Incontinence was counted as the most influential f</a>
<a title="European Medical Journal 1.1 2016 page 58" href="http://viewer.zmags.com/publication/8169c6ab?page=58"> URINARY INCONTINENCE, DEPRESSION, AND PSYC</a>
<a title="European Medical Journal 1.1 2016 page 59" href="http://viewer.zmags.com/publication/8169c6ab?page=59"> research around psychosocial factors </a>
<a title="European Medical Journal 1.1 2016 page 60" href="http://viewer.zmags.com/publication/8169c6ab?page=60"> the specific type of urinary incontinence is usual</a>
<a title="European Medical Journal 1.1 2016 page 61" href="http://viewer.zmags.com/publication/8169c6ab?page=61"> Table 1: Urinary incontinence and depression stud</a>
<a title="European Medical Journal 1.1 2016 page 62" href="http://viewer.zmags.com/publication/8169c6ab?page=62"> Table 1 continued. Author Country Participant</a>
<a title="European Medical Journal 1.1 2016 page 63" href="http://viewer.zmags.com/publication/8169c6ab?page=63"> significant higher scores for depression </a>
<a title="European Medical Journal 1.1 2016 page 64" href="http://viewer.zmags.com/publication/8169c6ab?page=64"> Table 2 continued. Author Country Participant</a>
<a title="European Medical Journal 1.1 2016 page 65" href="http://viewer.zmags.com/publication/8169c6ab?page=65"> Table 2 continued. Author Country Participant</a>
<a title="European Medical Journal 1.1 2016 page 66" href="http://viewer.zmags.com/publication/8169c6ab?page=66"> comorbid depression may be less likely to seek he</a>
<a title="European Medical Journal 1.1 2016 page 67" href="http://viewer.zmags.com/publication/8169c6ab?page=67"> tract symptoms and depression on health- related </a>
<a title="European Medical Journal 1.1 2016 page 68" href="http://viewer.zmags.com/publication/8169c6ab?page=68"> THE ROLE OF BODY FLUIDS IN THE HORIZONTAL T</a>
<a title="European Medical Journal 1.1 2016 page 69" href="http://viewer.zmags.com/publication/8169c6ab?page=69"> Horizontal transmission through household contact</a>
<a title="European Medical Journal 1.1 2016 page 70" href="http://viewer.zmags.com/publication/8169c6ab?page=70"> Table 1: HBsAg-positive rate of body fluids in pat</a>
<a title="European Medical Journal 1.1 2016 page 71" href="http://viewer.zmags.com/publication/8169c6ab?page=71"> Table 2 continued. Year Author No. of subje</a>
<a title="European Medical Journal 1.1 2016 page 72" href="http://viewer.zmags.com/publication/8169c6ab?page=72"> Table 3: Infectivity of serum and body fluids with</a>
<a title="European Medical Journal 1.1 2016 page 73" href="http://viewer.zmags.com/publication/8169c6ab?page=73"> DNA levels, tears, saliva (including nasopharynge</a>
<a title="European Medical Journal 1.1 2016 page 74" href="http://viewer.zmags.com/publication/8169c6ab?page=74"> REFERENCES 1. Trépo C et al. Hepatitis B virus i</a>
<a title="European Medical Journal 1.1 2016 page 75" href="http://viewer.zmags.com/publication/8169c6ab?page=75"> 46. Scott RM et al. Experimental transm</a>
<a title="European Medical Journal 1.1 2016 page 76" href="http://viewer.zmags.com/publication/8169c6ab?page=76"> EMJ EUROPEAN MEDICAL </a>
<a title="European Medical Journal 1.1 2016 page 77" href="http://viewer.zmags.com/publication/8169c6ab?page=77"> UTILITY OF EXOSOMES IN THE DIAGNOSIS AND TREATM</a>
<a title="European Medical Journal 1.1 2016 page 78" href="http://viewer.zmags.com/publication/8169c6ab?page=78"> STRUCTURE OF EXOSOMES The classification of a par</a>
<a title="European Medical Journal 1.1 2016 page 79" href="http://viewer.zmags.com/publication/8169c6ab?page=79"> with α6β4 (an integrin laminin receptor</a>
<a title="European Medical Journal 1.1 2016 page 80" href="http://viewer.zmags.com/publication/8169c6ab?page=80"> and DynaBeads. However, the authors cited a</a>
<a title="European Medical Journal 1.1 2016 page 81" href="http://viewer.zmags.com/publication/8169c6ab?page=81"> exosomal biomarkers as diagnostic tests </a>
<a title="European Medical Journal 1.1 2016 page 82" href="http://viewer.zmags.com/publication/8169c6ab?page=82"> Table 1 continued. Study Year Specimen type a</a>
<a title="European Medical Journal 1.1 2016 page 83" href="http://viewer.zmags.com/publication/8169c6ab?page=83"> cell-mediated cytotoxic T-cell responses. Exosoma</a>
<a title="European Medical Journal 1.1 2016 page 84" href="http://viewer.zmags.com/publication/8169c6ab?page=84"> CONCLUSION Exosomes possess unique molecular cha</a>
<a title="European Medical Journal 1.1 2016 page 85" href="http://viewer.zmags.com/publication/8169c6ab?page=85"> 35. Klein-Scory S et al. New insights in the comp</a>
<a title="European Medical Journal 1.1 2016 page 86" href="http://viewer.zmags.com/publication/8169c6ab?page=86"> HUMAN SPERM CRYOPRESERVATION *Eva Mocé,1 Andrés J</a>
<a title="European Medical Journal 1.1 2016 page 87" href="http://viewer.zmags.com/publication/8169c6ab?page=87"> stored on dry ice. However, it took another 20 ye</a>
<a title="European Medical Journal 1.1 2016 page 88" href="http://viewer.zmags.com/publication/8169c6ab?page=88"> intracellularly and extracellularly. Extracell</a>
<a title="European Medical Journal 1.1 2016 page 89" href="http://viewer.zmags.com/publication/8169c6ab?page=89"> Slow-freezing protocols are still ine</a>
<a title="European Medical Journal 1.1 2016 page 90" href="http://viewer.zmags.com/publication/8169c6ab?page=90"> ARE THESE TECHNIQUES SAFE? All of the techniq</a>
<a title="European Medical Journal 1.1 2016 page 91" href="http://viewer.zmags.com/publication/8169c6ab?page=91"> Cryobiology,” Woodruff TK, Snyder KA (eds.), Onco</a>
<a title="European Medical Journal 1.1 2016 page 92" href="http://viewer.zmags.com/publication/8169c6ab?page=92"> EUROPEAN MEDICAL JOURNAL provides influential arti</a>
<a title="European Medical Journal 1.1 2016 page 93" href="http://viewer.zmags.com/publication/8169c6ab?page=93"> PRESCHOOL WHEEZING PHENOTYPES *Andre</a>
<a title="European Medical Journal 1.1 2016 page 94" href="http://viewer.zmags.com/publication/8169c6ab?page=94"> IS IT WHEEZE AT ALL? The word ‘wheeze’ is us</a>
<a title="European Medical Journal 1.1 2016 page 95" href="http://viewer.zmags.com/publication/8169c6ab?page=95"> Table 1: Components of the proposed Hargreave phe</a>
<a title="European Medical Journal 1.1 2016 page 96" href="http://viewer.zmags.com/publication/8169c6ab?page=96"> accepting that regular review and possible change</a>
<a title="European Medical Journal 1.1 2016 page 97" href="http://viewer.zmags.com/publication/8169c6ab?page=97"> It is a diagnosis of exclusion; more serious cond</a>
<a title="European Medical Journal 1.1 2016 page 98" href="http://viewer.zmags.com/publication/8169c6ab?page=98"> Table 3: Phenotyping preschool paediatric wheezin</a>
<a title="European Medical Journal 1.1 2016 page 99" href="http://viewer.zmags.com/publication/8169c6ab?page=99"> gestation and an increased burden of asthma even </a>
<a title="European Medical Journal 1.1 2016 page 100" href="http://viewer.zmags.com/publication/8169c6ab?page=100"> SUMMARY AND CONCLUSION Here we have proposed </a>
<a title="European Medical Journal 1.1 2016 page 101" href="http://viewer.zmags.com/publication/8169c6ab?page=101"> receptor antagonist in preschool children with </a>
<a title="European Medical Journal 1.1 2016 page 102" href="http://viewer.zmags.com/publication/8169c6ab?page=102"> SUBSCRIBE TO RECEIVE THE LATEST PUBLICATIONS, NE</a>