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<br /> CARDIOLOGY<br /> ISSN 2054-3174 Vol 3.1 • February 2015 • emjreviews.com<br /> CONTENTS<br /> EDITORIAL BOARD................................................................................................................................. 4<br /> EDITOR’S PICK: STATE OF THE ART OF AORTIC VALVE IMPLANTATION: INDICATIONS,<br /> OUTCOMES, AND CONTROVERSIES.......................................................................................................... 10<br /> • Pablo Salinas et al.<br /> COST-EFFECTIVENESS OF A NOVEL SELF-APPOSING STENT IN ST-SEGMENT ELEVATION<br /> MYOCARDIAL INFARCTION (STEMI) IN FRANCE................................................................................... 22<br /> • Lieven Annemans et al.<br /> LEFT VENTRICULAR CARDIOMYOPATHY IN MITRAL VALVE PROLAPSE: FACT OR FICTION? 30<br /> • Christina Attenhofer Jost et al.<br /> FUNCTIONAL MITRAL REGURGITATION: I<a title="EMJ Cardiology 3.1 2015 page 1" href="http://viewer.zmags.com/publication/a4eed8b8?page=1"> CARDIOLOGY ISSN 2054-3174 </a> <a title="EMJ Cardiology 3.1 2015 page 2" href="http://viewer.zmags.com/publication/a4eed8b8?page=2"> CONTENTS EDITORIAL BOARD.......................</a> <a title="EMJ Cardiology 3.1 2015 page 3" href="http://viewer.zmags.com/publication/a4eed8b8?page=3"> CARDIOLOGY TRANSCATHETER OPTIONS FOR TREATMENT </a> <a title="EMJ Cardiology 3.1 2015 page 4" href="http://viewer.zmags.com/publication/a4eed8b8?page=4"> Editorial Board Editor-in-Chief: Dr Fernando A</a> <a title="EMJ Cardiology 3.1 2015 page 5" href="http://viewer.zmags.com/publication/a4eed8b8?page=5"> Cardiology Prof Robert Page, Professor, Depa</a> <a title="EMJ Cardiology 3.1 2015 page 6" href="http://viewer.zmags.com/publication/a4eed8b8?page=6"> European Medical Journal EMJ Cardiology Vol 3.1</a> <a title="EMJ Cardiology 3.1 2015 page 7" href="http://viewer.zmags.com/publication/a4eed8b8?page=7"> Welcome The field of Cardiology is one which ha</a> <a title="EMJ Cardiology 3.1 2015 page 8" href="http://viewer.zmags.com/publication/a4eed8b8?page=8"> Exceptional speakers will present the three plena</a> <a title="EMJ Cardiology 3.1 2015 page 9" href="http://viewer.zmags.com/publication/a4eed8b8?page=9"> Foreword Dr Fernando Alfonso Hospital</a> <a title="EMJ Cardiology 3.1 2015 page 10" href="http://viewer.zmags.com/publication/a4eed8b8?page=10"> EDITOR’S PICK I wo</a> <a title="EMJ Cardiology 3.1 2015 page 11" href="http://viewer.zmags.com/publication/a4eed8b8?page=11"> or systematic trials were performed, SAVR showed </a> <a title="EMJ Cardiology 3.1 2015 page 12" href="http://viewer.zmags.com/publication/a4eed8b8?page=12"> a careful evaluation of patients, medical treatme</a> <a title="EMJ Cardiology 3.1 2015 page 13" href="http://viewer.zmags.com/publication/a4eed8b8?page=13"> Table 1: Short and mid-term SOU registry UK r</a> <a title="EMJ Cardiology 3.1 2015 page 14" href="http://viewer.zmags.com/publication/a4eed8b8?page=14"> Table 2: Long-term mortality after TAVI. The orig</a> <a title="EMJ Cardiology 3.1 2015 page 15" href="http://viewer.zmags.com/publication/a4eed8b8?page=15"> arterial dissection/rupture and need for covered </a> <a title="EMJ Cardiology 3.1 2015 page 16" href="http://viewer.zmags.com/publication/a4eed8b8?page=16"> practice in most centres is PCI at least on sever</a> <a title="EMJ Cardiology 3.1 2015 page 17" href="http://viewer.zmags.com/publication/a4eed8b8?page=17"> TAVI will also promote advancements in othe</a> <a title="EMJ Cardiology 3.1 2015 page 18" href="http://viewer.zmags.com/publication/a4eed8b8?page=18"> computed tomography predicts moderate or severe p</a> <a title="EMJ Cardiology 3.1 2015 page 19" href="http://viewer.zmags.com/publication/a4eed8b8?page=19"> transcatheter and surgical prosthetic valve </a> <a title="EMJ Cardiology 3.1 2015 page 20" href="http://viewer.zmags.com/publication/a4eed8b8?page=20"> 101. Mack MJ et al; STS/ACC TVT Registry. Outcome</a> <a title="EMJ Cardiology 3.1 2015 page 21" href="http://viewer.zmags.com/publication/a4eed8b8?page=21"> SUBSCRIBE FREE TO OUR YOUTUBE CHANNEL www.youtube</a> <a title="EMJ Cardiology 3.1 2015 page 22" href="http://viewer.zmags.com/publication/a4eed8b8?page=22"> COST-EFFECTIVENESS OF A NOVEL SELF-APPOSING ST</a> <a title="EMJ Cardiology 3.1 2015 page 23" href="http://viewer.zmags.com/publication/a4eed8b8?page=23"> would be substantial,4 but recent real-life </a> <a title="EMJ Cardiology 3.1 2015 page 24" href="http://viewer.zmags.com/publication/a4eed8b8?page=24"> not related to MI, and CV death. Therefore, we al</a> <a title="EMJ Cardiology 3.1 2015 page 25" href="http://viewer.zmags.com/publication/a4eed8b8?page=25"> Table 1: Clinical input data for first 30 </a> <a title="EMJ Cardiology 3.1 2015 page 26" href="http://viewer.zmags.com/publication/a4eed8b8?page=26"> Table 3: Utility data applied in the model. Event</a> <a title="EMJ Cardiology 3.1 2015 page 27" href="http://viewer.zmags.com/publication/a4eed8b8?page=27"> to conventional DES (€16,291/QALY) but not cost- </a> <a title="EMJ Cardiology 3.1 2015 page 28" href="http://viewer.zmags.com/publication/a4eed8b8?page=28"> Early economic models have some limitations, as i</a> <a title="EMJ Cardiology 3.1 2015 page 29" href="http://viewer.zmags.com/publication/a4eed8b8?page=29"> APPOSITION III investigators. A Post- market </a> <a title="EMJ Cardiology 3.1 2015 page 30" href="http://viewer.zmags.com/publication/a4eed8b8?page=30"> LEFT VENTRICULAR CARDIOMYOPATHY IN MITRAL </a> <a title="EMJ Cardiology 3.1 2015 page 31" href="http://viewer.zmags.com/publication/a4eed8b8?page=31"> (LV) dysfunction and clinical features of HF. An </a> <a title="EMJ Cardiology 3.1 2015 page 32" href="http://viewer.zmags.com/publication/a4eed8b8?page=32"> A 5 10 LV 15 V LA </a> <a title="EMJ Cardiology 3.1 2015 page 33" href="http://viewer.zmags.com/publication/a4eed8b8?page=33"> circulating troponin I concentration correlat</a> <a title="EMJ Cardiology 3.1 2015 page 34" href="http://viewer.zmags.com/publication/a4eed8b8?page=34"> Table 1: Summary of left and right ventricular ab</a> <a title="EMJ Cardiology 3.1 2015 page 35" href="http://viewer.zmags.com/publication/a4eed8b8?page=35"> Myocardial impairment including abnormal LV r</a> <a title="EMJ Cardiology 3.1 2015 page 36" href="http://viewer.zmags.com/publication/a4eed8b8?page=36"> population-based sample of American Indians: t</a> <a title="EMJ Cardiology 3.1 2015 page 37" href="http://viewer.zmags.com/publication/a4eed8b8?page=37"> 53. Jaffe AS et al. Mitral valve prolapse: a cons</a> <a title="EMJ Cardiology 3.1 2015 page 38" href="http://viewer.zmags.com/publication/a4eed8b8?page=38"> FUNCTIONAL MITRAL REGURGITATION: IF THE MYOCARDI</a> <a title="EMJ Cardiology 3.1 2015 page 39" href="http://viewer.zmags.com/publication/a4eed8b8?page=39"> prolapse or PM rupture; Type 3: coaptation proxim</a> <a title="EMJ Cardiology 3.1 2015 page 40" href="http://viewer.zmags.com/publication/a4eed8b8?page=40"> Dyssynchrony of the LV results in the dyssynchron</a> <a title="EMJ Cardiology 3.1 2015 page 41" href="http://viewer.zmags.com/publication/a4eed8b8?page=41"> A B Fig</a> <a title="EMJ Cardiology 3.1 2015 page 42" href="http://viewer.zmags.com/publication/a4eed8b8?page=42"> Functional MR OMT CAD therapy Consider CRT Sy</a> <a title="EMJ Cardiology 3.1 2015 page 43" href="http://viewer.zmags.com/publication/a4eed8b8?page=43"> positive response to CRT, it appears unquestionab</a> <a title="EMJ Cardiology 3.1 2015 page 44" href="http://viewer.zmags.com/publication/a4eed8b8?page=44"> versus 2.3%) but a similar perioperative mortalit</a> <a title="EMJ Cardiology 3.1 2015 page 45" href="http://viewer.zmags.com/publication/a4eed8b8?page=45"> indirect annuloplasty. Based on the anatomic</a> <a title="EMJ Cardiology 3.1 2015 page 46" href="http://viewer.zmags.com/publication/a4eed8b8?page=46"> CONCLUSION FMR is a complex disease pr</a> <a title="EMJ Cardiology 3.1 2015 page 47" href="http://viewer.zmags.com/publication/a4eed8b8?page=47"> of mitral repair for functional mitral regur</a> <a title="EMJ Cardiology 3.1 2015 page 48" href="http://viewer.zmags.com/publication/a4eed8b8?page=48"> TRANSCATHETER OPTIONS FOR TREATMENT OF </a> <a title="EMJ Cardiology 3.1 2015 page 49" href="http://viewer.zmags.com/publication/a4eed8b8?page=49"> of application, following established sur</a> <a title="EMJ Cardiology 3.1 2015 page 50" href="http://viewer.zmags.com/publication/a4eed8b8?page=50"> the procedure was documented. Until January </a> <a title="EMJ Cardiology 3.1 2015 page 51" href="http://viewer.zmags.com/publication/a4eed8b8?page=51"> Figure 2: The Carillon Mitral Contour System cons</a> <a title="EMJ Cardiology 3.1 2015 page 52" href="http://viewer.zmags.com/publication/a4eed8b8?page=52"> Treatment of Mitral Regurgitation) have been</a> <a title="EMJ Cardiology 3.1 2015 page 53" href="http://viewer.zmags.com/publication/a4eed8b8?page=53"> Direct annuloplasty Several devices for dir</a> <a title="EMJ Cardiology 3.1 2015 page 54" href="http://viewer.zmags.com/publication/a4eed8b8?page=54"> It has to be emphasised that both patients</a> <a title="EMJ Cardiology 3.1 2015 page 55" href="http://viewer.zmags.com/publication/a4eed8b8?page=55"> programme likely relieved undertreatment </a> <a title="EMJ Cardiology 3.1 2015 page 56" href="http://viewer.zmags.com/publication/a4eed8b8?page=56"> Coll Cardiol. 2009;54:638-51. 26. Lansac E et al.</a> <a title="EMJ Cardiology 3.1 2015 page 57" href="http://viewer.zmags.com/publication/a4eed8b8?page=57"> Would you like to write for the EMJ blog? Intera</a> <a title="EMJ Cardiology 3.1 2015 page 58" href="http://viewer.zmags.com/publication/a4eed8b8?page=58"> CIRCULATING HAEMOGLOBIN LEVELS AND THE RISK OF </a> <a title="EMJ Cardiology 3.1 2015 page 59" href="http://viewer.zmags.com/publication/a4eed8b8?page=59"> Changes in diet and lifestyle promoted by the hos</a> <a title="EMJ Cardiology 3.1 2015 page 60" href="http://viewer.zmags.com/publication/a4eed8b8?page=60"> apolipoproteins A1 and B), anthropometry (body ma</a> <a title="EMJ Cardiology 3.1 2015 page 61" href="http://viewer.zmags.com/publication/a4eed8b8?page=61"> Table 1A continued. Risk factors, dietary intake</a> <a title="EMJ Cardiology 3.1 2015 page 62" href="http://viewer.zmags.com/publication/a4eed8b8?page=62"> = 0.18, P<0.001) and paraoxonase activity (partia</a> <a title="EMJ Cardiology 3.1 2015 page 63" href="http://viewer.zmags.com/publication/a4eed8b8?page=63"> Table 2: Haematological parameters and oxidative </a> <a title="EMJ Cardiology 3.1 2015 page 64" href="http://viewer.zmags.com/publication/a4eed8b8?page=64"> genetic predisposition to bloodborne disorder</a> <a title="EMJ Cardiology 3.1 2015 page 65" href="http://viewer.zmags.com/publication/a4eed8b8?page=65"> However, HDL cholesterol and homocysteine were no</a> <a title="EMJ Cardiology 3.1 2015 page 66" href="http://viewer.zmags.com/publication/a4eed8b8?page=66"> REFERENCES 1. Reddy KS, Yusuf S. Emerging epidem</a> <a title="EMJ Cardiology 3.1 2015 page 67" href="http://viewer.zmags.com/publication/a4eed8b8?page=67"> THE PROGRAM ON THE SURGICAL CONTROL OF THE HYPERL</a> <a title="EMJ Cardiology 3.1 2015 page 68" href="http://viewer.zmags.com/publication/a4eed8b8?page=68"> that cholesterol is transported to the arterial w</a> <a title="EMJ Cardiology 3.1 2015 page 69" href="http://viewer.zmags.com/publication/a4eed8b8?page=69"> Table 1: Change in low-density lipoprotein (LDL) </a> <a title="EMJ Cardiology 3.1 2015 page 70" href="http://viewer.zmags.com/publication/a4eed8b8?page=70"> Table 3: Change in cholesterol retention fraction</a> <a title="EMJ Cardiology 3.1 2015 page 71" href="http://viewer.zmags.com/publication/a4eed8b8?page=71"> measured colourimetrically. Once HDL cholesterol </a> <a title="EMJ Cardiology 3.1 2015 page 72" href="http://viewer.zmags.com/publication/a4eed8b8?page=72"> two cholesterol transport fractions in predicting</a> <a title="EMJ Cardiology 3.1 2015 page 73" href="http://viewer.zmags.com/publication/a4eed8b8?page=73"> 0.7 0.6 0.5 0.4 Rate of Plaque Progression</a> <a title="EMJ Cardiology 3.1 2015 page 74" href="http://viewer.zmags.com/publication/a4eed8b8?page=74"> thus is superior to LDL cholesterol in predicting</a> <a title="EMJ Cardiology 3.1 2015 page 75" href="http://viewer.zmags.com/publication/a4eed8b8?page=75"> 0.25 mmol/l lower than one calculated by the ne</a> <a title="EMJ Cardiology 3.1 2015 page 76" href="http://viewer.zmags.com/publication/a4eed8b8?page=76"> on the progression of coronary athero</a> <a title="EMJ Cardiology 3.1 2015 page 77" href="http://viewer.zmags.com/publication/a4eed8b8?page=77"> EUROPEAN MEDICAL JOURNAL provides influential arti</a> <a title="EMJ Cardiology 3.1 2015 page 78" href="http://viewer.zmags.com/publication/a4eed8b8?page=78"> HOW I TREAT: CORONARY HEART DISEAS THE PLEIOTR</a> <a title="EMJ Cardiology 3.1 2015 page 79" href="http://viewer.zmags.com/publication/a4eed8b8?page=79"> Furthermore, numerous large observational studies</a> <a title="EMJ Cardiology 3.1 2015 page 80" href="http://viewer.zmags.com/publication/a4eed8b8?page=80"> SUBSCRIBE TO RECEIVE THE LATEST CATIONS PUBLI</a>