<br />
ALLERGY & IMMUNOLOGY<br />
ISSN 2398-9130 Vol 1.1 • August 2016 • emjreviews.com<br />
INSIDE<br />
Review of<br />
EAACI 2016<br />
Vienna, Austria<br />
CONTENTS<br />
EDITORIAL BOARD......................................................................................................................................... 4<br />
CONGRESS REVIEW........................................................................................................................................ 12<br />
• Review of the 60th European Academy of Allergy and Clinical Immunology<br />
(EAACI) Annual Congress, held in Vienna, Austria, 11th–15th June 2016<br />
INTERVIEWS WITH EMJ ALLERGY & IMMUNOLOGY EDITORIAL BOARD........................................ 20<br />
SYMPOSIUM REVIEWS<br />
• ADJUVANTS IN ALLERGY: ELEVATING EFFICACY...........................................................<a title="EMJ Allergy & Immunology 1.1 2016 page 1" href="http://viewer.zmags.com/publication/c54acbb8?page=1"> ALLERGY & IMMUNOLOGY ISSN 2398-9130 </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 2" href="http://viewer.zmags.com/publication/c54acbb8?page=2"> CONTENTS EDITORIAL BOARD.......................</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 3" href="http://viewer.zmags.com/publication/c54acbb8?page=3"> ALLERGY & IMMUNOLOGY • ATOPIC DERMATITIS: THE</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 4" href="http://viewer.zmags.com/publication/c54acbb8?page=4"> Editorial Board Editor-in-Chief: Prof Dr Jacqu</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 5" href="http://viewer.zmags.com/publication/c54acbb8?page=5"> Allergy & Immunology Dr Rodrigo Rodrigues, Di</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 6" href="http://viewer.zmags.com/publication/c54acbb8?page=6"> SUBSCRIBE TOTHEEMJ NEWSLETTER NwEwwW.newSs.eLmjEr</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 7" href="http://viewer.zmags.com/publication/c54acbb8?page=7"> Welcome Welcome to EMJ Allergy & Immunology, t</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 8" href="http://viewer.zmags.com/publication/c54acbb8?page=8"> Introducing Nucala, the first targeted anti-IL-5 </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 9" href="http://viewer.zmags.com/publication/c54acbb8?page=9"> Foreword </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 10" href="http://viewer.zmags.com/publication/c54acbb8?page=10"> Have you read the European Medical Journal? </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 11" href="http://viewer.zmags.com/publication/c54acbb8?page=11"> able now on our website, featuring articles from </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 12" href="http://viewer.zmags.com/publication/c54acbb8?page=12"> 12 ALLERGY & IMMUNOLOGY • August 2016 </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 13" href="http://viewer.zmags.com/publication/c54acbb8?page=13"> ALLERGY & IMMUNOLOGY • August 2016 </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 14" href="http://viewer.zmags.com/publication/c54acbb8?page=14"> 14 ALLERGY & IMMUNOLOGY • August 2016 </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 15" href="http://viewer.zmags.com/publication/c54acbb8?page=15"> Congress Highlights President of EAA</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 16" href="http://viewer.zmags.com/publication/c54acbb8?page=16"> </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 17" href="http://viewer.zmags.com/publication/c54acbb8?page=17"> EAACI Publishes a User’s Guide to Molecular Aller</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 18" href="http://viewer.zmags.com/publication/c54acbb8?page=18"> Over 1,800 abstracts for discussion EAACI Calls </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 19" href="http://viewer.zmags.com/publication/c54acbb8?page=19"> Exclusive Interviews from the German Cancer </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 20" href="http://viewer.zmags.com/publication/c54acbb8?page=20"> Frans Timmermans Vice President of the Netherlan</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 21" href="http://viewer.zmags.com/publication/c54acbb8?page=21"> people with allergies cope in their daily </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 22" href="http://viewer.zmags.com/publication/c54acbb8?page=22"> she knows what they react to and if the </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 23" href="http://viewer.zmags.com/publication/c54acbb8?page=23"> Q: What are likely to be the biggest challenges f</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 24" href="http://viewer.zmags.com/publication/c54acbb8?page=24"> ‘impressions’ and therefore respiratory aller</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 25" href="http://viewer.zmags.com/publication/c54acbb8?page=25"> Q: What do you feel to be the greatest achievemen</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 26" href="http://viewer.zmags.com/publication/c54acbb8?page=26"> in some patients. Recent research indicated that </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 27" href="http://viewer.zmags.com/publication/c54acbb8?page=27"> of Vienna, Vienna, Austria), which brings togethe</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 28" href="http://viewer.zmags.com/publication/c54acbb8?page=28"> of allergic diseases in Malaysia, particularly fo</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 29" href="http://viewer.zmags.com/publication/c54acbb8?page=29"> Q: In light of your involvement with the Allergy-</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 30" href="http://viewer.zmags.com/publication/c54acbb8?page=30"> With their knowledge we can build the nati</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 31" href="http://viewer.zmags.com/publication/c54acbb8?page=31"> Q: What are some of the greatest challenges you c</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 32" href="http://viewer.zmags.com/publication/c54acbb8?page=32"> ADJUVANTS IN ALLERGY: ELEVATING EFFICACY This </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 33" href="http://viewer.zmags.com/publication/c54acbb8?page=33"> in 790 German patients in Germany undergoing AIT </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 34" href="http://viewer.zmags.com/publication/c54acbb8?page=34"> advances in AIT exceed the effects of symptomatic</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 35" href="http://viewer.zmags.com/publication/c54acbb8?page=35"> Other than increasing allergen dose, which may ha</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 36" href="http://viewer.zmags.com/publication/c54acbb8?page=36"> REFERENCES 1. Durham SR et al. SQ-standardi</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 37" href="http://viewer.zmags.com/publication/c54acbb8?page=37"> IMPROVING DIAGNOSIS: THE NEXT FRONTIER IN HE</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 38" href="http://viewer.zmags.com/publication/c54acbb8?page=38"> Diagnosing Hereditary Angioedema Patients To</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 39" href="http://viewer.zmags.com/publication/c54acbb8?page=39"> event. Some current diagnostic tests may ha</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 40" href="http://viewer.zmags.com/publication/c54acbb8?page=40"> vascular endothelial-like growth factor (VEGF</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 41" href="http://viewer.zmags.com/publication/c54acbb8?page=41"> Bradykinin Kininase Bradykinin fra</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 42" href="http://viewer.zmags.com/publication/c54acbb8?page=42"> between histaminergic reactions and the formation</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 43" href="http://viewer.zmags.com/publication/c54acbb8?page=43"> of the disease, genetic testing may be the most p</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 44" href="http://viewer.zmags.com/publication/c54acbb8?page=44"> Aw d W n a e o nA </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 45" href="http://viewer.zmags.com/publication/c54acbb8?page=45"> normal daily routine. The researchers sought to </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 46" href="http://viewer.zmags.com/publication/c54acbb8?page=46"> Poster Discussion Sessions In the </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 47" href="http://viewer.zmags.com/publication/c54acbb8?page=47"> The conclusions drawn from their longitudinal ana</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 48" href="http://viewer.zmags.com/publication/c54acbb8?page=48"> Abstract Reviews CLIMATE CHANGE IMPACT ON POLLE</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 49" href="http://viewer.zmags.com/publication/c54acbb8?page=49"> EAACI 2016 Therefore, transport with wind,</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 50" href="http://viewer.zmags.com/publication/c54acbb8?page=50"> Abstract Reviews apple species contain fewer all</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 51" href="http://viewer.zmags.com/publication/c54acbb8?page=51"> EAACI 2016 the effect of dupilumab on HRQoL outc</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 52" href="http://viewer.zmags.com/publication/c54acbb8?page=52"> EDITOR’S PICK This</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 53" href="http://viewer.zmags.com/publication/c54acbb8?page=53"> INTRODUCTION Drug allergy or drug hypersensi</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 54" href="http://viewer.zmags.com/publication/c54acbb8?page=54"> Table 2 continued. Reaction type Type of immune r</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 55" href="http://viewer.zmags.com/publication/c54acbb8?page=55"> Table 2: Differential diagnosis of drug allergy a</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 56" href="http://viewer.zmags.com/publication/c54acbb8?page=56"> MANAGEMENT OF COMMON DRUG ALLERGIES The most e</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 57" href="http://viewer.zmags.com/publication/c54acbb8?page=57"> Anaesthetics True allergic reactions to l</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 58" href="http://viewer.zmags.com/publication/c54acbb8?page=58"> ATOPIC DERMATITIS: THE NEED FOR A SUB-SA</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 59" href="http://viewer.zmags.com/publication/c54acbb8?page=59"> The data on African populations is thus sparse an</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 60" href="http://viewer.zmags.com/publication/c54acbb8?page=60"> Culex Anopheles A</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 61" href="http://viewer.zmags.com/publication/c54acbb8?page=61"> conditioning dendritic cell (DC) maturati</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 62" href="http://viewer.zmags.com/publication/c54acbb8?page=62"> brain microvessels and on infected erythrocytes f</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 63" href="http://viewer.zmags.com/publication/c54acbb8?page=63"> is a highly prevalent ‘environmental’ allerg</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 64" href="http://viewer.zmags.com/publication/c54acbb8?page=64"> Study. J Allergy Clin Immunol. 2012;129(3): 840-5</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 65" href="http://viewer.zmags.com/publication/c54acbb8?page=65"> Would you like to write for the EMJ blog? Interac</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 66" href="http://viewer.zmags.com/publication/c54acbb8?page=66"> IN SEARCH OF BIOMARKERS IN EOSINOPHILIC OESOP</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 67" href="http://viewer.zmags.com/publication/c54acbb8?page=67"> recurrence.1,5 Reliable, non-invasive bioma</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 68" href="http://viewer.zmags.com/publication/c54acbb8?page=68"> Genome-wide microarray expression analysis in</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 69" href="http://viewer.zmags.com/publication/c54acbb8?page=69"> significantly downregulated oesophageal IL-5</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 70" href="http://viewer.zmags.com/publication/c54acbb8?page=70"> with oesophageal eosinophil counts compared with </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 71" href="http://viewer.zmags.com/publication/c54acbb8?page=71"> general, and may not be specific to oesophageal mu</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 72" href="http://viewer.zmags.com/publication/c54acbb8?page=72"> on potential biomarkers for EoE. Eotaxi</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 73" href="http://viewer.zmags.com/publication/c54acbb8?page=73"> Clin Immunol. 2013;132:3-14. 38. Lu S et al. Micr</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 74" href="http://viewer.zmags.com/publication/c54acbb8?page=74"> TREATMENT OPTIONS IN EOSINOPHILIC OESOPHAGITIS </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 75" href="http://viewer.zmags.com/publication/c54acbb8?page=75"> antagonist, have emerged in recent years wi</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 76" href="http://viewer.zmags.com/publication/c54acbb8?page=76"> Table 1: Eosinophilic oesophagitis treatment summ</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 77" href="http://viewer.zmags.com/publication/c54acbb8?page=77"> in maintaining clinical or histological remission</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 78" href="http://viewer.zmags.com/publication/c54acbb8?page=78"> radioallergosorbent or skin-prick tests. </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 79" href="http://viewer.zmags.com/publication/c54acbb8?page=79"> Oesophageal biopsies with ≥15 EOS/HPF at 5 cm </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 80" href="http://viewer.zmags.com/publication/c54acbb8?page=80"> 1066-78. 4. Dellon ES, Liacouras CA. Advances in </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 81" href="http://viewer.zmags.com/publication/c54acbb8?page=81"> Am J Gastroenterol. 2003;98(4):777-82. 46. Liaco</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 82" href="http://viewer.zmags.com/publication/c54acbb8?page=82"> ASTHMA PHENOTYPES AND THE MICROBIOME </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 83" href="http://viewer.zmags.com/publication/c54acbb8?page=83"> that characterises only ~50% of patient</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 84" href="http://viewer.zmags.com/publication/c54acbb8?page=84"> This parallels a recent editorial by Stappenbeck </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 85" href="http://viewer.zmags.com/publication/c54acbb8?page=85"> the production of short-chain fatty acids (SCFA),</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 86" href="http://viewer.zmags.com/publication/c54acbb8?page=86"> Table 1 continued. Author Year Significa</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 87" href="http://viewer.zmags.com/publication/c54acbb8?page=87"> Feeding mice a diet high in fermentable fib</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 88" href="http://viewer.zmags.com/publication/c54acbb8?page=88"> Concurrent steroid treatment may influence these fi</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 89" href="http://viewer.zmags.com/publication/c54acbb8?page=89"> REFERENCES 1. Wenzel SE. Asthma phenotypes: the </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 90" href="http://viewer.zmags.com/publication/c54acbb8?page=90"> interactions between the gut microbiota and host</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 91" href="http://viewer.zmags.com/publication/c54acbb8?page=91"> If you are interested in submitting a paper to </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 92" href="http://viewer.zmags.com/publication/c54acbb8?page=92"> DRUG ALLERGY: DELAYED CUTANEOUS HYPERSENSITIVI</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 93" href="http://viewer.zmags.com/publication/c54acbb8?page=93"> a list of the most common drugs that have been fo</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 94" href="http://viewer.zmags.com/publication/c54acbb8?page=94"> hypersensitivity reaction; allopurinol drug react</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 95" href="http://viewer.zmags.com/publication/c54acbb8?page=95"> Table 2: The Gell and Coombs classification system</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 96" href="http://viewer.zmags.com/publication/c54acbb8?page=96"> associated with contact dermatitis (Type IV) will</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 97" href="http://viewer.zmags.com/publication/c54acbb8?page=97"> Table 3: Drug hypersensitivity reactions based on</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 98" href="http://viewer.zmags.com/publication/c54acbb8?page=98"> Table 4: Severe cutaneous adverse reactions. Stev</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 99" href="http://viewer.zmags.com/publication/c54acbb8?page=99"> severity of the symptoms, both cutaneous an</a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 100" href="http://viewer.zmags.com/publication/c54acbb8?page=100"> Skin care after full closure includes use of sun </a>
<a title="EMJ Allergy & Immunology 1.1 2016 page 101" href="http://viewer.zmags.com/publication/c54acbb8?page=101"> 34. Miyazaki M et al. Acute liver failure caused </a>
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<a title="EMJ Allergy & Immunology 1.1 2016 page 106" href="http://viewer.zmags.com/publication/c54acbb8?page=106"> UPCOMING EVENTS 17th Biennial Meeting of the Euro</a>
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