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RESPIRATORY
ELAIR supplement • emjreviews.com
INSIDE
Summary of Selected Presentations
ELAIR Summit
Buenos Aires, Argentina, 2015
CONTENTS
Narrative Summary of Selected Presentations Given at the
Second Encuentro Latinoamericano de Infecciones Respiratorias
Recurrentes (ELAIR), an Educational Summit held in
Buenos Aires, Argentina, 4th–5th July 2015
THE PLACE OF IMMUNOMODULATION IN RECURRENT RESPIRATORY TRACT INFECTIONS,
AN OVERLOOKED PANDEMIC..................................................................................................................... 3
• Enrique Mansilla, Alberto Ciceran, Shirley Pignatari, Ana M. Koatz,
Ricardo L. Marengo
RESPIRATORY TRACT INFECTIONS IN PAEDIATRIC PATIENTS: PREVENTION OF
RECURRENCE AND BEYOND...........................................................................................
RESPIRATORY ELAIR supplement • emjreviews.com
CONTENTS Narrative Summary of Selected Pr
THE PLACE OF IMMUNOMODULATION IN RECURRENT
of factors, including damage to the respira
preventative therapy, targeting infection in gene
relies on activity in Peyer’s patches, the induct
30 Proportion of patients experiencing URTIs/AOM
3 2 Mean number of infections at Month 6 1
the healthcare system. The immunomodulator
RESPIRATORY TRACT INFECTIONS IN PAEDIATRIC P
RSV increases in parallel with the RTI symptom se
placenta, reaches a peak in the neonatal period b
8 6 4 Cumulative number of wheezing attack
wheezing was also noted, as were decreases in air
40 Frequency (n) 20 0 IIV (n=35) 31 IIV
to the healthcare system were €48.52/patient over
immunological properties of the bacterial extract
THE KEY ROLE OF PREVENTATIVE STRATEGIES IN C
underdiagnosed, likely to constitute a great
The related ‘Goldilocks hypothesis’ postulates th
Initiating factors e.g.
INFECTION-SPECIFIC PROPHYLACTIC STRATEGIES FOR CO
A Episodes of acute infection (n) 5 4 3 2
reduced proportion of patients with ≥2 acut
2002;347(7):465-71. 17. Soler-Cataluna JJ et al.
2005;10(5):209-17. 62. Orcel B et al. Oral immuni
RESPIRATORY IMMUNITY AND THE RATIONALE FOR IMMUN
mechanism. The second line of innate defenc
cell types with differing effects depending
OM-85 and Innate Immunity OM-85 has a number
5 4 3 Percentage of CD3+ CD8+ nucleoprot
8 6 (ng/mL) 4 IFNγ 2 0 IFNγ 600 IL-4
important in forms of asthma associated wit