If you are visually impaired or blind, you can visit the PDF version by Pressing CONTROL + ALT + 4
<br /> GASTROENTEROLOGY<br /> ISSN 2054-6203 Vol 5.1 • December 2016 • emjreviews.com<br /> INSIDE<br /> Review of<br /> UEG WEEK 2016<br /> Vienna, Austria<br /> CONTENTS<br /> EDITORIAL BOARD...................................................................................................................................... 4<br /> CONGRESS REVIEW.................................................................................................................................... 10<br /> • Review of the 24th United European Gastroenterology (UEG) Week, held in Vienna,<br /> Austria, 15th–19th October 2016<br /> INTERVIEWS WITH EMJ GASTROENTEROLOGY EDITORIAL BOARD............................................ 18<br /> SYMPOSIUM REVIEWS<br /> • PREVENTING COLLATERAL DAMAGE IN THE INFLAMMATORY BOWEL DISEASE<br /> PATIENT: USING DISEASE ASSESSMENT AND PROGNOSTIC FACTORS TO OPTIMISE<br /> CLINI<a title="EMJ Gastroenterology 5.1 2016 page 1" href="http://viewer.zmags.com/publication/c9649179?page=1"> GASTROENTEROLOGY ISSN 2054-6203 </a> <a title="EMJ Gastroenterology 5.1 2016 page 2" href="http://viewer.zmags.com/publication/c9649179?page=2"> CONTENTS EDITORIAL BOARD.......................</a> <a title="EMJ Gastroenterology 5.1 2016 page 3" href="http://viewer.zmags.com/publication/c9649179?page=3"> GASTROENTEROLOGY • ASSESSING ALTERATIONS IN FOO</a> <a title="EMJ Gastroenterology 5.1 2016 page 4" href="http://viewer.zmags.com/publication/c9649179?page=4"> Editorial Board Editor-in-Chief: Dr Jan Borns</a> <a title="EMJ Gastroenterology 5.1 2016 page 5" href="http://viewer.zmags.com/publication/c9649179?page=5"> Gastroenterology Prof Abe Fingerhut, Professo</a> <a title="EMJ Gastroenterology 5.1 2016 page 6" href="http://viewer.zmags.com/publication/c9649179?page=6"> GASTROENTEROLOGY 5.1 DECEMBER 2016 Director Spe</a> <a title="EMJ Gastroenterology 5.1 2016 page 7" href="http://viewer.zmags.com/publication/c9649179?page=7"> Welcome Greetings, and welcome to the 2016 edi</a> <a title="EMJ Gastroenterology 5.1 2016 page 8" href="http://viewer.zmags.com/publication/c9649179?page=8"> See what you could be missing. </a> <a title="EMJ Gastroenterology 5.1 2016 page 9" href="http://viewer.zmags.com/publication/c9649179?page=9"> Foreword </a> <a title="EMJ Gastroenterology 5.1 2016 page 10" href="http://viewer.zmags.com/publication/c9649179?page=10"> 10 GASTROENTEROLOGY • December 2016 </a> <a title="EMJ Gastroenterology 5.1 2016 page 11" href="http://viewer.zmags.com/publication/c9649179?page=11"> GASTROENTEROLOGY • December 2016 </a> <a title="EMJ Gastroenterology 5.1 2016 page 12" href="http://viewer.zmags.com/publication/c9649179?page=12"> 12 GASTROENTEROLOGY • December 2016 </a> <a title="EMJ Gastroenterology 5.1 2016 page 13" href="http://viewer.zmags.com/publication/c9649179?page=13"> Congress Highlights Updates to Guide</a> <a title="EMJ Gastroenterology 5.1 2016 page 14" href="http://viewer.zmags.com/publication/c9649179?page=14"> access different pathways, ultimately leading to </a> <a title="EMJ Gastroenterology 5.1 2016 page 15" href="http://viewer.zmags.com/publication/c9649179?page=15"> Dr Bennet commented: “This raises the p</a> <a title="EMJ Gastroenterology 5.1 2016 page 16" href="http://viewer.zmags.com/publication/c9649179?page=16"> The Berliner TransitionsProgramm: Care for Young </a> <a title="EMJ Gastroenterology 5.1 2016 page 17" href="http://viewer.zmags.com/publication/c9649179?page=17"> Protein in Wheat Triggers Inflammation of Chronic </a> <a title="EMJ Gastroenterology 5.1 2016 page 18" href="http://viewer.zmags.com/publication/c9649179?page=18"> Sorin T. Barbu Professor of Surgery, “Iuliu Hati</a> <a title="EMJ Gastroenterology 5.1 2016 page 19" href="http://viewer.zmags.com/publication/c9649179?page=19"> Randomised controlled trials have demonstrated la</a> <a title="EMJ Gastroenterology 5.1 2016 page 20" href="http://viewer.zmags.com/publication/c9649179?page=20"> (the first surgeon to be in this organisati</a> <a title="EMJ Gastroenterology 5.1 2016 page 21" href="http://viewer.zmags.com/publication/c9649179?page=21"> guidelines for diagnosis and management, but</a> <a title="EMJ Gastroenterology 5.1 2016 page 22" href="http://viewer.zmags.com/publication/c9649179?page=22"> The paper ‘Analysis of research activit</a> <a title="EMJ Gastroenterology 5.1 2016 page 23" href="http://viewer.zmags.com/publication/c9649179?page=23"> of Patras, Patras, Greece, I undertook an electiv</a> <a title="EMJ Gastroenterology 5.1 2016 page 24" href="http://viewer.zmags.com/publication/c9649179?page=24"> One of the highlights of UEG Week is the </a> <a title="EMJ Gastroenterology 5.1 2016 page 25" href="http://viewer.zmags.com/publication/c9649179?page=25"> Q: Research in the field of the gut microbiome and</a> <a title="EMJ Gastroenterology 5.1 2016 page 26" href="http://viewer.zmags.com/publication/c9649179?page=26"> I have experienced how important it can be when t</a> <a title="EMJ Gastroenterology 5.1 2016 page 27" href="http://viewer.zmags.com/publication/c9649179?page=27"> A: It is an excellent platform for medical</a> <a title="EMJ Gastroenterology 5.1 2016 page 28" href="http://viewer.zmags.com/publication/c9649179?page=28"> PREVENTING COLLATERAL DAMAGE IN THE INF</a> <a title="EMJ Gastroenterology 5.1 2016 page 29" href="http://viewer.zmags.com/publication/c9649179?page=29"> inflammation in IBD can lead to poor outcomes, and</a> <a title="EMJ Gastroenterology 5.1 2016 page 30" href="http://viewer.zmags.com/publication/c9649179?page=30"> Simple demographic and clinical features can guid</a> <a title="EMJ Gastroenterology 5.1 2016 page 31" href="http://viewer.zmags.com/publication/c9649179?page=31"> disease state. An asymptomatic patient with CD ha</a> <a title="EMJ Gastroenterology 5.1 2016 page 32" href="http://viewer.zmags.com/publication/c9649179?page=32"> The impact of the disease on patients with CD has</a> <a title="EMJ Gastroenterology 5.1 2016 page 33" href="http://viewer.zmags.com/publication/c9649179?page=33"> (London, England). 2015;386(10006): 1825-34. </a> <a title="EMJ Gastroenterology 5.1 2016 page 34" href="http://viewer.zmags.com/publication/c9649179?page=34"> INTRODUCING BIOSIMILARS INTO CURRENT INFLAMMATOR</a> <a title="EMJ Gastroenterology 5.1 2016 page 35" href="http://viewer.zmags.com/publication/c9649179?page=35"> and 23 biological assays, a Phase I study demonst</a> <a title="EMJ Gastroenterology 5.1 2016 page 36" href="http://viewer.zmags.com/publication/c9649179?page=36"> pharmaceutical form and strength, indications</a> <a title="EMJ Gastroenterology 5.1 2016 page 37" href="http://viewer.zmags.com/publication/c9649179?page=37"> ADAs. Data from reference infliximab clinical tria</a> <a title="EMJ Gastroenterology 5.1 2016 page 38" href="http://viewer.zmags.com/publication/c9649179?page=38"> patients receiving SB2 continued to receive SB2 u</a> <a title="EMJ Gastroenterology 5.1 2016 page 39" href="http://viewer.zmags.com/publication/c9649179?page=39"> 100 80 SB2 ACR20 SB2 ACR50 SB2 ACR70 60 40</a> <a title="EMJ Gastroenterology 5.1 2016 page 40" href="http://viewer.zmags.com/publication/c9649179?page=40"> Transferring Clinical Data into Clinical Prac</a> <a title="EMJ Gastroenterology 5.1 2016 page 41" href="http://viewer.zmags.com/publication/c9649179?page=41"> 7. European Medicines Agency, Committee for Medic</a> <a title="EMJ Gastroenterology 5.1 2016 page 42" href="http://viewer.zmags.com/publication/c9649179?page=42"> Tillotts Pharma AG (“Tillotts”), part of the Japa</a> <a title="EMJ Gastroenterology 5.1 2016 page 43" href="http://viewer.zmags.com/publication/c9649179?page=43"> RELEVANCE OF PATIENT-REPORTED OUTCOMES FOR TH</a> <a title="EMJ Gastroenterology 5.1 2016 page 44" href="http://viewer.zmags.com/publication/c9649179?page=44"> Learning Objectives The aim of this webinar was t</a> <a title="EMJ Gastroenterology 5.1 2016 page 45" href="http://viewer.zmags.com/publication/c9649179?page=45"> patient themselves and based on the patient</a> <a title="EMJ Gastroenterology 5.1 2016 page 46" href="http://viewer.zmags.com/publication/c9649179?page=46"> patients to take control of their own health, cre</a> <a title="EMJ Gastroenterology 5.1 2016 page 47" href="http://viewer.zmags.com/publication/c9649179?page=47"> Table 2: Safety of inflammatory bowel disease drug</a> <a title="EMJ Gastroenterology 5.1 2016 page 48" href="http://viewer.zmags.com/publication/c9649179?page=48"> Summary and Conclusions As the knowledge and </a> <a title="EMJ Gastroenterology 5.1 2016 page 49" href="http://viewer.zmags.com/publication/c9649179?page=49"> CROHN’S DISEASE: SUPPORTING PATIENTS IN THEIR </a> <a title="EMJ Gastroenterology 5.1 2016 page 50" href="http://viewer.zmags.com/publication/c9649179?page=50"> 70 Patients requiring major surgery (%) 60 50 </a> <a title="EMJ Gastroenterology 5.1 2016 page 51" href="http://viewer.zmags.com/publication/c9649179?page=51"> Yes Biologics </a> <a title="EMJ Gastroenterology 5.1 2016 page 52" href="http://viewer.zmags.com/publication/c9649179?page=52"> 15 years as a monotherapy, as part of combination</a> <a title="EMJ Gastroenterology 5.1 2016 page 53" href="http://viewer.zmags.com/publication/c9649179?page=53"> To achieve full control of CD, the focus must be </a> <a title="EMJ Gastroenterology 5.1 2016 page 54" href="http://viewer.zmags.com/publication/c9649179?page=54"> that, anti-TNFs are also effective. It is also im</a> <a title="EMJ Gastroenterology 5.1 2016 page 55" href="http://viewer.zmags.com/publication/c9649179?page=55"> profile, and rapidly clears systemic inflammation. </a> <a title="EMJ Gastroenterology 5.1 2016 page 56" href="http://viewer.zmags.com/publication/c9649179?page=56"> an open randomised trial. Lancet. 2008;37</a> <a title="EMJ Gastroenterology 5.1 2016 page 57" href="http://viewer.zmags.com/publication/c9649179?page=57"> Exclusive Interviews from the 24th United </a> <a title="EMJ Gastroenterology 5.1 2016 page 58" href="http://viewer.zmags.com/publication/c9649179?page=58"> Abstract Reviews EXPERIENCE OF THE </a> <a title="EMJ Gastroenterology 5.1 2016 page 59" href="http://viewer.zmags.com/publication/c9649179?page=59"> UEG 2016 A Kaplan–Meier survival curve was perfo</a> <a title="EMJ Gastroenterology 5.1 2016 page 60" href="http://viewer.zmags.com/publication/c9649179?page=60"> Abstract Reviews from both the upper and lower r</a> <a title="EMJ Gastroenterology 5.1 2016 page 61" href="http://viewer.zmags.com/publication/c9649179?page=61"> UEG 2016 best exam to obtain this classification </a> <a title="EMJ Gastroenterology 5.1 2016 page 62" href="http://viewer.zmags.com/publication/c9649179?page=62"> Abstract Reviews Our experience with endoscop</a> <a title="EMJ Gastroenterology 5.1 2016 page 63" href="http://viewer.zmags.com/publication/c9649179?page=63"> UEG 2016 surgery should it become necessary, eit</a> <a title="EMJ Gastroenterology 5.1 2016 page 64" href="http://viewer.zmags.com/publication/c9649179?page=64"> Abstract Reviews treatment (starting at 30–32 we</a> <a title="EMJ Gastroenterology 5.1 2016 page 65" href="http://viewer.zmags.com/publication/c9649179?page=65"> UEG 2016 1990 to 2013: findings from the Global B</a> <a title="EMJ Gastroenterology 5.1 2016 page 66" href="http://viewer.zmags.com/publication/c9649179?page=66"> Abstract Reviews achieve complete polyp resectio</a> <a title="EMJ Gastroenterology 5.1 2016 page 67" href="http://viewer.zmags.com/publication/c9649179?page=67"> UEG 2016 PLR 7.27, 95% CI: 3.74–14.2); Rome</a> <a title="EMJ Gastroenterology 5.1 2016 page 68" href="http://viewer.zmags.com/publication/c9649179?page=68"> Abstract Reviews colonoscopist blinded to the in</a> <a title="EMJ Gastroenterology 5.1 2016 page 69" href="http://viewer.zmags.com/publication/c9649179?page=69"> UEG 2016 small tumour pieces distinguished betwe</a> <a title="EMJ Gastroenterology 5.1 2016 page 70" href="http://viewer.zmags.com/publication/c9649179?page=70"> Abstract Reviews Complete snare resection </a> <a title="EMJ Gastroenterology 5.1 2016 page 71" href="http://viewer.zmags.com/publication/c9649179?page=71"> UEG 2016 UNSUPERVISED TRANSCRIPTOMICS- BASED CL</a> <a title="EMJ Gastroenterology 5.1 2016 page 72" href="http://viewer.zmags.com/publication/c9649179?page=72"> Abstract Reviews Conversely, the subgroup exh</a> <a title="EMJ Gastroenterology 5.1 2016 page 73" href="http://viewer.zmags.com/publication/c9649179?page=73"> UEG 2016 medications and/or prokinetics were sto</a> <a title="EMJ Gastroenterology 5.1 2016 page 74" href="http://viewer.zmags.com/publication/c9649179?page=74"> EDITOR’S PICK In this pe</a> <a title="EMJ Gastroenterology 5.1 2016 page 75" href="http://viewer.zmags.com/publication/c9649179?page=75"> INTRODUCTION Proton pump inhibitors (PPI) were i</a> <a title="EMJ Gastroenterology 5.1 2016 page 76" href="http://viewer.zmags.com/publication/c9649179?page=76"> PROTON PUMP INHIBITORS AND NUTRITIONAL DEFICIENCY</a> <a title="EMJ Gastroenterology 5.1 2016 page 77" href="http://viewer.zmags.com/publication/c9649179?page=77"> reduce ascorbic acid and cobalamin levels, leadin</a> <a title="EMJ Gastroenterology 5.1 2016 page 78" href="http://viewer.zmags.com/publication/c9649179?page=78"> evaluating regular PPI use in patients with gastr</a> <a title="EMJ Gastroenterology 5.1 2016 page 79" href="http://viewer.zmags.com/publication/c9649179?page=79"> Data for the years 2004–2011 was obtained from Ge</a> <a title="EMJ Gastroenterology 5.1 2016 page 80" href="http://viewer.zmags.com/publication/c9649179?page=80"> 138(3):896-904. 13. Ngamruengphong S et al. </a> <a title="EMJ Gastroenterology 5.1 2016 page 81" href="http://viewer.zmags.com/publication/c9649179?page=81"> 57. Antoniou T et al. Proton pump inhibitors and </a> <a title="EMJ Gastroenterology 5.1 2016 page 82" href="http://viewer.zmags.com/publication/c9649179?page=82"> ASSESSING ALTERATIONS IN FOOD PREFERENCE AS A </a> <a title="EMJ Gastroenterology 5.1 2016 page 83" href="http://viewer.zmags.com/publication/c9649179?page=83"> absolute threshold of dietary fat tolerance, by 1</a> <a title="EMJ Gastroenterology 5.1 2016 page 84" href="http://viewer.zmags.com/publication/c9649179?page=84"> and 3 months postoperatively. The RYGB group demo</a> <a title="EMJ Gastroenterology 5.1 2016 page 85" href="http://viewer.zmags.com/publication/c9649179?page=85"> breakpoint between groups.22 However, we have see</a> <a title="EMJ Gastroenterology 5.1 2016 page 86" href="http://viewer.zmags.com/publication/c9649179?page=86"> the pleasure attributed to a specific food reward </a> <a title="EMJ Gastroenterology 5.1 2016 page 87" href="http://viewer.zmags.com/publication/c9649179?page=87"> (PET) with a D2 receptor agonist radioligand was </a> <a title="EMJ Gastroenterology 5.1 2016 page 88" href="http://viewer.zmags.com/publication/c9649179?page=88"> 10. El Labban S et al. The Effect of Roux</a> <a title="EMJ Gastroenterology 5.1 2016 page 89" href="http://viewer.zmags.com/publication/c9649179?page=89"> EOSINOPHILIC OESOPHAGITIS: </a> <a title="EMJ Gastroenterology 5.1 2016 page 90" href="http://viewer.zmags.com/publication/c9649179?page=90"> EOSINOPHILIC OESOPHAGITIS: A TRULY BRIEF HISTORY </a> <a title="EMJ Gastroenterology 5.1 2016 page 91" href="http://viewer.zmags.com/publication/c9649179?page=91"> OESOPHAGEAL MICROBIOME AND EOSINOPHILIC OESOPHAGI</a> <a title="EMJ Gastroenterology 5.1 2016 page 92" href="http://viewer.zmags.com/publication/c9649179?page=92"> LOCAL IMMUNOGLOBULIN E PRODUCTION Local IgE prod</a> <a title="EMJ Gastroenterology 5.1 2016 page 93" href="http://viewer.zmags.com/publication/c9649179?page=93"> change. In the report of Kagawalla et al.,</a> <a title="EMJ Gastroenterology 5.1 2016 page 94" href="http://viewer.zmags.com/publication/c9649179?page=94"> other allergic disease continued, and the number </a> <a title="EMJ Gastroenterology 5.1 2016 page 95" href="http://viewer.zmags.com/publication/c9649179?page=95"> 12(4):589-96.e1. 10. Alexander ES et al. Twin and</a> <a title="EMJ Gastroenterology 5.1 2016 page 96" href="http://viewer.zmags.com/publication/c9649179?page=96"> EOSINOPHILIC OESOPHAGITIS: CURRENT UNDERSTANDI</a> <a title="EMJ Gastroenterology 5.1 2016 page 97" href="http://viewer.zmags.com/publication/c9649179?page=97"> This review also highlights emerging controversie</a> <a title="EMJ Gastroenterology 5.1 2016 page 98" href="http://viewer.zmags.com/publication/c9649179?page=98"> Patients with EoE are commonly young adults</a> <a title="EMJ Gastroenterology 5.1 2016 page 99" href="http://viewer.zmags.com/publication/c9649179?page=99"> (e.g. urticaria, anaphylaxis). Patients’ response</a> <a title="EMJ Gastroenterology 5.1 2016 page 100" href="http://viewer.zmags.com/publication/c9649179?page=100"> A B C D E F Figure 2: Characteristic endoscop</a> <a title="EMJ Gastroenterology 5.1 2016 page 101" href="http://viewer.zmags.com/publication/c9649179?page=101"> Both dysmotility and fibrosis contribute </a> <a title="EMJ Gastroenterology 5.1 2016 page 102" href="http://viewer.zmags.com/publication/c9649179?page=102"> Oesophageal eosinophilia on biopsy 8-WEEK PP</a> <a title="EMJ Gastroenterology 5.1 2016 page 103" href="http://viewer.zmags.com/publication/c9649179?page=103"> this benefit is sustained.50 A 50-week randomised </a> <a title="EMJ Gastroenterology 5.1 2016 page 104" href="http://viewer.zmags.com/publication/c9649179?page=104"> predicts fibrotic complications34 suggesting t</a> <a title="EMJ Gastroenterology 5.1 2016 page 105" href="http://viewer.zmags.com/publication/c9649179?page=105"> epidemic of eosinophilic oesophagitis. Best Pr</a> <a title="EMJ Gastroenterology 5.1 2016 page 106" href="http://viewer.zmags.com/publication/c9649179?page=106"> budesonide maintenance treatment is part</a> <a title="EMJ Gastroenterology 5.1 2016 page 107" href="http://viewer.zmags.com/publication/c9649179?page=107"> INFLIXIMAB AND TUMOUR NECROSIS FACTOR ALPHA </a> <a title="EMJ Gastroenterology 5.1 2016 page 108" href="http://viewer.zmags.com/publication/c9649179?page=108"> INTRODUCTION Inflammatory bowel disease (IBD) </a> <a title="EMJ Gastroenterology 5.1 2016 page 109" href="http://viewer.zmags.com/publication/c9649179?page=109"> and other influencing factors which are yet to be </a> <a title="EMJ Gastroenterology 5.1 2016 page 110" href="http://viewer.zmags.com/publication/c9649179?page=110"> track-etched membrane in 24 multiwell plates</a> <a title="EMJ Gastroenterology 5.1 2016 page 111" href="http://viewer.zmags.com/publication/c9649179?page=111"> IFX levels </a> <a title="EMJ Gastroenterology 5.1 2016 page 112" href="http://viewer.zmags.com/publication/c9649179?page=112"> were pooled together. Similar findings were found </a> <a title="EMJ Gastroenterology 5.1 2016 page 113" href="http://viewer.zmags.com/publication/c9649179?page=113"> These demonstrated the interaction betwee</a> <a title="EMJ Gastroenterology 5.1 2016 page 114" href="http://viewer.zmags.com/publication/c9649179?page=114"> REFERENCES 1. Strober W et al. The fundamental b</a> <a title="EMJ Gastroenterology 5.1 2016 page 115" href="http://viewer.zmags.com/publication/c9649179?page=115"> macrophages and decreased IL-17 expressi</a> <a title="EMJ Gastroenterology 5.1 2016 page 116" href="http://viewer.zmags.com/publication/c9649179?page=116"> BARRETT’S OESOPHAGUS IN 2016 </a> <a title="EMJ Gastroenterology 5.1 2016 page 117" href="http://viewer.zmags.com/publication/c9649179?page=117"> patients who were undergoing colonoscopy and neve</a> <a title="EMJ Gastroenterology 5.1 2016 page 118" href="http://viewer.zmags.com/publication/c9649179?page=118"> and bile,29 thus duodenogastro-oesophageal reflux </a> <a title="EMJ Gastroenterology 5.1 2016 page 119" href="http://viewer.zmags.com/publication/c9649179?page=119"> Barrett's mucosa Figure 4: Endo</a> <a title="EMJ Gastroenterology 5.1 2016 page 120" href="http://viewer.zmags.com/publication/c9649179?page=120"> • Aged >50 years • Non-Hispanic white populat</a> <a title="EMJ Gastroenterology 5.1 2016 page 121" href="http://viewer.zmags.com/publication/c9649179?page=121"> SURVEILLANCE The main objective of surveillance </a> <a title="EMJ Gastroenterology 5.1 2016 page 122" href="http://viewer.zmags.com/publication/c9649179?page=122"> eradicating both intestinal metaplasia and dyspla</a> <a title="EMJ Gastroenterology 5.1 2016 page 123" href="http://viewer.zmags.com/publication/c9649179?page=123"> a surveillance programme. All patients with BO </a> <a title="EMJ Gastroenterology 5.1 2016 page 124" href="http://viewer.zmags.com/publication/c9649179?page=124"> adenocarcinoma of the esophagus or cardia. Ca</a> <a title="EMJ Gastroenterology 5.1 2016 page 125" href="http://viewer.zmags.com/publication/c9649179?page=125"> MONOCLONAL ANTIBODY-BASED THERAPY FOR EOS</a> <a title="EMJ Gastroenterology 5.1 2016 page 126" href="http://viewer.zmags.com/publication/c9649179?page=126"> The treatment of EoE is complex, requiring the us</a> <a title="EMJ Gastroenterology 5.1 2016 page 127" href="http://viewer.zmags.com/publication/c9649179?page=127"> INTERLEUKIN-5 The tissue localisation of IL-5 in</a> <a title="EMJ Gastroenterology 5.1 2016 page 128" href="http://viewer.zmags.com/publication/c9649179?page=128"> a fully humanised mAb against the IL-4R-α chain, </a> <a title="EMJ Gastroenterology 5.1 2016 page 129" href="http://viewer.zmags.com/publication/c9649179?page=129"> increased soluble IL-5 receptor alpha in the </a> <a title="EMJ Gastroenterology 5.1 2016 page 130" href="http://viewer.zmags.com/publication/c9649179?page=130"> Buyer’s Guide • 3D MATRIX • ABBVIE • ALFA W</a> <a title="EMJ Gastroenterology 5.1 2016 page 131" href="http://viewer.zmags.com/publication/c9649179?page=131"> Gastroenterology • INVENDO MEDICAL GMBH • JA</a> <a title="EMJ Gastroenterology 5.1 2016 page 132" href="http://viewer.zmags.com/publication/c9649179?page=132"> SUBSCRIBE TO RECEIVE THE LATEST PUBLICATIONS, NE</a>