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<br /> ARCHIVE<br /> VOLUME 111 NUMBER 1 JANUARY 2016<br /> www.nature.com/ajg<br /> official publication of the american college of gastroenterology<br /> LEADING ARTICLES OF THE MONTH<br /> The Red Section: EndoTech Update<br /> 6 Just Clip It: Endoscopic Clipping in the 21st Century<br /> B. Joseph Elmunzer<br /> Practice Guidelines<br /> 30 ACG Clinical Guideline: Diagnosis and Management of Barrett’s<br /> Esophagus CME<br /> N.J. Shaheen, G.W. Falk, P.G. Iyer and L.B. Gerson<br /> Clinical and Systematic Reviews<br /> 53 Diagnosis and Management of Functional Heartburn CME<br /> C. Hachem and N.J. Shaheen<br /> Endoscopy<br /> 63 Effect of Dynamic Position Changes on Adenoma Detection during<br /> Colonoscope Withdrawal: A Randomized Controlled Multicenter Trial<br /> S.-W. Lee, J.H. Chang, J.-S. Ji et al.<br /> Liver<br /> 78 Diagnosis of Minima<a title="AJG_Vol.111.No.05 page 1" href="http://viewer.zmags.com/publication/d54b80bd?page=1"> ARCHIVE VOLUME 111 NUMBER 1 JANUARY 2016 www.natu</a> <a title="AJG_Vol.111.No.05 page 2" href="http://viewer.zmags.com/publication/d54b80bd?page=2"> VOLUME 111 NUMBER 5 MAY 2016 www.nature.com/ajg</a> <a title="AJG_Vol.111.No.05 page 3" href="http://viewer.zmags.com/publication/d54b80bd?page=3"> PERFORMANCE meets PREFERENCE* *by patients in cl</a> <a title="AJG_Vol.111.No.05 page 4" href="http://viewer.zmags.com/publication/d54b80bd?page=4"> In the pivotal, Phase III, non-inferiority study </a> <a title="AJG_Vol.111.No.05 page 5" href="http://viewer.zmags.com/publication/d54b80bd?page=5"> The following is a brief summary only; see full P</a> <a title="AJG_Vol.111.No.05 page 6" href="http://viewer.zmags.com/publication/d54b80bd?page=6"> www.amjgastro.com The American Journa</a> <a title="AJG_Vol.111.No.05 page 7" href="http://viewer.zmags.com/publication/d54b80bd?page=7"> Albert Einstein used with permission of the HUJ/G</a> <a title="AJG_Vol.111.No.05 page 8" href="http://viewer.zmags.com/publication/d54b80bd?page=8"> HARVONI DELIVERED HIGH CURE (SVR) RATES IN SUBJEC</a> <a title="AJG_Vol.111.No.05 page 9" href="http://viewer.zmags.com/publication/d54b80bd?page=9"> HARVONI IS THE ONLY SINGLE-TABLET REGIMEN FOR HCV</a> <a title="AJG_Vol.111.No.05 page 10" href="http://viewer.zmags.com/publication/d54b80bd?page=10"> FOR TREATING CHRONIC HCV GT 1 BE THE ONE WHO CAN</a> <a title="AJG_Vol.111.No.05 page 11" href="http://viewer.zmags.com/publication/d54b80bd?page=11"> HARVONI® (ledipasvir 90 mg and sofosbuvir 400 mg)</a> <a title="AJG_Vol.111.No.05 page 12" href="http://viewer.zmags.com/publication/d54b80bd?page=12"> Brief Summary (cont.) Postmarketing Experience: B</a> <a title="AJG_Vol.111.No.05 page 13" href="http://viewer.zmags.com/publication/d54b80bd?page=13"> Come visit us at Clinical Evidence Supports DDW</a> <a title="AJG_Vol.111.No.05 page 14" href="http://viewer.zmags.com/publication/d54b80bd?page=14"> BRIEF SUMMARY UCERIS (budesonide) extended releas</a> <a title="AJG_Vol.111.No.05 page 15" href="http://viewer.zmags.com/publication/d54b80bd?page=15"> In active, mild to moderate ulcerative colitis (U</a> <a title="AJG_Vol.111.No.05 page 16" href="http://viewer.zmags.com/publication/d54b80bd?page=16"> OFFICIAL PUBLICATION OF THE AMERICAN CO</a> <a title="AJG_Vol.111.No.05 page 17" href="http://viewer.zmags.com/publication/d54b80bd?page=17"> In patients with Lysosomal Acid Lipase Deficiency </a> <a title="AJG_Vol.111.No.05 page 18" href="http://viewer.zmags.com/publication/d54b80bd?page=18"> Nearly 90% mortality within 12 months after birth</a> <a title="AJG_Vol.111.No.05 page 19" href="http://viewer.zmags.com/publication/d54b80bd?page=19"> LEARN AND EARN CME WHILE YOU STAY</a> <a title="AJG_Vol.111.No.05 page 20" href="http://viewer.zmags.com/publication/d54b80bd?page=20"> VIBERZI (eluxadoline) tablets, for oral use, CIV </a> <a title="AJG_Vol.111.No.05 page 21" href="http://viewer.zmags.com/publication/d54b80bd?page=21"> RECOMMEND THE MOST POWERFUL OTC PPI FROM THE STAR</a> <a title="AJG_Vol.111.No.05 page 22" href="http://viewer.zmags.com/publication/d54b80bd?page=22"> Left column top to bottom: Pre- infliximab endosco</a> <a title="AJG_Vol.111.No.05 page 23" href="http://viewer.zmags.com/publication/d54b80bd?page=23"> CONTENTS </a> <a title="AJG_Vol.111.No.05 page 24" href="http://viewer.zmags.com/publication/d54b80bd?page=24"> www.nature.com/ajg </a> <a title="AJG_Vol.111.No.05 page 25" href="http://viewer.zmags.com/publication/d54b80bd?page=25"> the potential to REVOLUTIONIZE We are Intercept. </a> <a title="AJG_Vol.111.No.05 page 26" href="http://viewer.zmags.com/publication/d54b80bd?page=26"> Treat IBS-Di erently A 2-week treatment for IBS-</a> <a title="AJG_Vol.111.No.05 page 27" href="http://viewer.zmags.com/publication/d54b80bd?page=27"> BRIEF SUMMARY OF PRESCRIBING INFORMATION This Bri</a> <a title="AJG_Vol.111.No.05 page 28" href="http://viewer.zmags.com/publication/d54b80bd?page=28"> NOW APPROVED For more information, v</a> <a title="AJG_Vol.111.No.05 page 29" href="http://viewer.zmags.com/publication/d54b80bd?page=29"> Find resources, clinical results, and dosing info</a> <a title="AJG_Vol.111.No.05 page 30" href="http://viewer.zmags.com/publication/d54b80bd?page=30"> For patients with active, mild to moderate ulcera</a> <a title="AJG_Vol.111.No.05 page 31" href="http://viewer.zmags.com/publication/d54b80bd?page=31"> BRIEF SUMMARY: Consult the Full Prescribing Infor</a> <a title="AJG_Vol.111.No.05 page 32" href="http://viewer.zmags.com/publication/d54b80bd?page=32"> not always possible to reliably estimate their fr</a> <a title="AJG_Vol.111.No.05 page 33" href="http://viewer.zmags.com/publication/d54b80bd?page=33"> Q&A: ADVERTORIAL Fecal Lactoferrin </a> <a title="AJG_Vol.111.No.05 page 34" href="http://viewer.zmags.com/publication/d54b80bd?page=34"> Don't your patients deserve to know what you alre</a> <a title="AJG_Vol.111.No.05 page 35" href="http://viewer.zmags.com/publication/d54b80bd?page=35"> CALL for ABSTRACTS ACG 2016 OCTOBER 14–19, 2</a> <a title="AJG_Vol.111.No.05 page 36" href="http://viewer.zmags.com/publication/d54b80bd?page=36"> ADVERSE REACTIONS: Clinical Trials in Adult Subje</a> <a title="AJG_Vol.111.No.05 page 37" href="http://viewer.zmags.com/publication/d54b80bd?page=37"> Michael R. Charlton, MD Intermountain Medical Cen</a> <a title="AJG_Vol.111.No.05 page 38" href="http://viewer.zmags.com/publication/d54b80bd?page=38"> DETECT EARLY. TREAT EARLY. PROACTIVE GI</a> <a title="AJG_Vol.111.No.05 page 39" href="http://viewer.zmags.com/publication/d54b80bd?page=39"> GI QUALITY IMPROVEMENT CONSORTIUM LTD 3 Se ing</a> <a title="AJG_Vol.111.No.05 page 40" href="http://viewer.zmags.com/publication/d54b80bd?page=40"> TURNING RESEARCH INTO RECOVERY FASTER. THAT'S </a> <a title="AJG_Vol.111.No.05 page 41" href="http://viewer.zmags.com/publication/d54b80bd?page=41"> With IBSchek™, now you can get a confident </a> <a title="AJG_Vol.111.No.05 page 42" href="http://viewer.zmags.com/publication/d54b80bd?page=42"> 65 Years of GI Endoscopy Innovation in One Powerf</a> <a title="AJG_Vol.111.No.05 page 43" href="http://viewer.zmags.com/publication/d54b80bd?page=43"> YOUR LAB EQUIPMENT RESOURCE nature.com/marketplac</a> <a title="AJG_Vol.111.No.05 page 44" href="http://viewer.zmags.com/publication/d54b80bd?page=44"> MAKE THE MOVE APRISO SAVINGS PROGRAM $0 $</a> <a title="AJG_Vol.111.No.05 page 45" href="http://viewer.zmags.com/publication/d54b80bd?page=45"> The following is a brief summary only. See comple</a> <a title="AJG_Vol.111.No.05 page 46" href="http://viewer.zmags.com/publication/d54b80bd?page=46"> Choose a probiotic worthy of your recommendation </a> <a title="AJG_Vol.111.No.05 page 47" href="http://viewer.zmags.com/publication/d54b80bd?page=47"> Download the NatureJournals app for iPad, iPhone </a> <a title="AJG_Vol.111.No.05 page 48" href="http://viewer.zmags.com/publication/d54b80bd?page=48"> BRIEF SUMMARY OF PRESCRIBING INFORMATION This Br</a> <a title="AJG_Vol.111.No.05 page 49" href="http://viewer.zmags.com/publication/d54b80bd?page=49"> nature publishing group </a> <a title="AJG_Vol.111.No.05 page 50" href="http://viewer.zmags.com/publication/d54b80bd?page=50"> 588 2019 Mer -based ncen ve paymen sys em </a> <a title="AJG_Vol.111.No.05 page 51" href="http://viewer.zmags.com/publication/d54b80bd?page=51"> nature publishing group </a> <a title="AJG_Vol.111.No.05 page 52" href="http://viewer.zmags.com/publication/d54b80bd?page=52"> 590 THE RED SECTION DIGITAL DIALOGUE Figure 1.</a> <a title="AJG_Vol.111.No.05 page 53" href="http://viewer.zmags.com/publication/d54b80bd?page=53"> THE RED SECTION 591 6,031 Patients scree</a> <a title="AJG_Vol.111.No.05 page 54" href="http://viewer.zmags.com/publication/d54b80bd?page=54"> 592 THE RED SECTION </a> <a title="AJG_Vol.111.No.05 page 55" href="http://viewer.zmags.com/publication/d54b80bd?page=55"> 7. Kurian AW, Hare EE, Mills MA et al. Clinical</a> <a title="AJG_Vol.111.No.05 page 56" href="http://viewer.zmags.com/publication/d54b80bd?page=56"> 594 THE RED SECTION </a> <a title="AJG_Vol.111.No.05 page 57" href="http://viewer.zmags.com/publication/d54b80bd?page=57"> I decided to branch out beyond colorectal ca</a> <a title="AJG_Vol.111.No.05 page 58" href="http://viewer.zmags.com/publication/d54b80bd?page=58"> 596 THE RED SECTION </a> <a title="AJG_Vol.111.No.05 page 59" href="http://viewer.zmags.com/publication/d54b80bd?page=59"> nature publishing group </a> <a title="AJG_Vol.111.No.05 page 60" href="http://viewer.zmags.com/publication/d54b80bd?page=60"> 598 THE RED SECTION </a> <a title="AJG_Vol.111.No.05 page 61" href="http://viewer.zmags.com/publication/d54b80bd?page=61"> nature publishing group </a> <a title="AJG_Vol.111.No.05 page 62" href="http://viewer.zmags.com/publication/d54b80bd?page=62"> 600 THE RED SECTION </a> <a title="AJG_Vol.111.No.05 page 63" href="http://viewer.zmags.com/publication/d54b80bd?page=63"> nature publishing group </a> <a title="AJG_Vol.111.No.05 page 64" href="http://viewer.zmags.com/publication/d54b80bd?page=64"> 602 PRACTICE GUIDELINES </a> <a title="AJG_Vol.111.No.05 page 65" href="http://viewer.zmags.com/publication/d54b80bd?page=65"> Clinical Guideline: Acute Diarrheal Infections </a> <a title="AJG_Vol.111.No.05 page 66" href="http://viewer.zmags.com/publication/d54b80bd?page=66"> 604 Riddle et al. Table 1. Summary and s</a> <a title="AJG_Vol.111.No.05 page 67" href="http://viewer.zmags.com/publication/d54b80bd?page=67"> destinations in 2014 (12), resulting in roughly 4</a> <a title="AJG_Vol.111.No.05 page 68" href="http://viewer.zmags.com/publication/d54b80bd?page=68"> 606 Riddle et al. Table 2. FDA-approved</a> <a title="AJG_Vol.111.No.05 page 69" href="http://viewer.zmags.com/publication/d54b80bd?page=69"> combination approach where culture specimens that</a> <a title="AJG_Vol.111.No.05 page 70" href="http://viewer.zmags.com/publication/d54b80bd?page=70"> 608 Riddle et al. Table 3. Randomized d</a> <a title="AJG_Vol.111.No.05 page 71" href="http://viewer.zmags.com/publication/d54b80bd?page=71"> 21/168 (12.5%) compared with 102/165 (62%) in the</a> <a title="AJG_Vol.111.No.05 page 72" href="http://viewer.zmags.com/publication/d54b80bd?page=72"> 610 Riddle et al. passed watery stools</a> <a title="AJG_Vol.111.No.05 page 73" href="http://viewer.zmags.com/publication/d54b80bd?page=73"> of therapy appears to be superior to single-dose </a> <a title="AJG_Vol.111.No.05 page 74" href="http://viewer.zmags.com/publication/d54b80bd?page=74"> 612 Riddle et al. 12. Endoscopic evaluat</a> <a title="AJG_Vol.111.No.05 page 75" href="http://viewer.zmags.com/publication/d54b80bd?page=75"> industries, stores, and restaurants but also pene</a> <a title="AJG_Vol.111.No.05 page 76" href="http://viewer.zmags.com/publication/d54b80bd?page=76"> 614 Riddle et al. resembling endemic s</a> <a title="AJG_Vol.111.No.05 page 77" href="http://viewer.zmags.com/publication/d54b80bd?page=77"> group, 20 in the placebo group), the use of sodiu</a> <a title="AJG_Vol.111.No.05 page 78" href="http://viewer.zmags.com/publication/d54b80bd?page=78"> 616 Riddle et al. of antibiotic use, r</a> <a title="AJG_Vol.111.No.05 page 79" href="http://viewer.zmags.com/publication/d54b80bd?page=79"> 30. Shah N, DuPont HL, Ramsey DJ. Global etiolo</a> <a title="AJG_Vol.111.No.05 page 80" href="http://viewer.zmags.com/publication/d54b80bd?page=80"> 618 Riddle et al. 82. Power SE, O'Too</a> <a title="AJG_Vol.111.No.05 page 81" href="http://viewer.zmags.com/publication/d54b80bd?page=81"> 132. Pepin J, Saheb N, Coulombe MA et al. Emergen</a> <a title="AJG_Vol.111.No.05 page 82" href="http://viewer.zmags.com/publication/d54b80bd?page=82"> 620 Riddle et al. 184. Olesen M, Erikss</a> <a title="AJG_Vol.111.No.05 page 83" href="http://viewer.zmags.com/publication/d54b80bd?page=83"> 238. Thabane M, Kottachchi DT, Marshall JK. Syste</a> <a title="AJG_Vol.111.No.05 page 84" href="http://viewer.zmags.com/publication/d54b80bd?page=84"> 622 Riddle et al. 5. Acute infectious </a> <a title="AJG_Vol.111.No.05 page 85" href="http://viewer.zmags.com/publication/d54b80bd?page=85"> nature publishing group </a> <a title="AJG_Vol.111.No.05 page 86" href="http://viewer.zmags.com/publication/d54b80bd?page=86"> 624 REVIEWS FROM THE ACG ANNUAL MEETING </a> <a title="AJG_Vol.111.No.05 page 87" href="http://viewer.zmags.com/publication/d54b80bd?page=87"> Figure 1. The modern examination room. to heal</a> <a title="AJG_Vol.111.No.05 page 88" href="http://viewer.zmags.com/publication/d54b80bd?page=88"> 626 Spiegel REVIEW Figure 3. Example of mH</a> <a title="AJG_Vol.111.No.05 page 89" href="http://viewer.zmags.com/publication/d54b80bd?page=89"> lives, and exchange notes about how they are mana</a> <a title="AJG_Vol.111.No.05 page 90" href="http://viewer.zmags.com/publication/d54b80bd?page=90"> 628 Spiegel Pain score 652500 2000 1</a> <a title="AJG_Vol.111.No.05 page 91" href="http://viewer.zmags.com/publication/d54b80bd?page=91"> How Digital Health Will Transform Gastroenterolog</a> <a title="AJG_Vol.111.No.05 page 92" href="http://viewer.zmags.com/publication/d54b80bd?page=92"> 630 Spiegel REVIEW 16. Weitzman ER, Adida </a> <a title="AJG_Vol.111.No.05 page 93" href="http://viewer.zmags.com/publication/d54b80bd?page=93"> nature publishing group </a> <a title="AJG_Vol.111.No.05 page 94" href="http://viewer.zmags.com/publication/d54b80bd?page=94"> 632 CLINICAL AND SYSTEMATIC REVIEWS </a> <a title="AJG_Vol.111.No.05 page 95" href="http://viewer.zmags.com/publication/d54b80bd?page=95"> Currently available data are insufficient to m</a> <a title="AJG_Vol.111.No.05 page 96" href="http://viewer.zmags.com/publication/d54b80bd?page=96"> 634 Gisbert et al. REVIEW was investigated</a> <a title="AJG_Vol.111.No.05 page 97" href="http://viewer.zmags.com/publication/d54b80bd?page=97"> Discontinuation of Anti-TNF in IBD 635 T</a> <a title="AJG_Vol.111.No.05 page 98" href="http://viewer.zmags.com/publication/d54b80bd?page=98"> 636 Gisbert et al. After anti-TNF wi</a> <a title="AJG_Vol.111.No.05 page 99" href="http://viewer.zmags.com/publication/d54b80bd?page=99"> Discontinuation of Anti-TNF in IBD 637 Ta</a> <a title="AJG_Vol.111.No.05 page 100" href="http://viewer.zmags.com/publication/d54b80bd?page=100"> 638 Gisbert et al. Table 3. Studies eva</a> <a title="AJG_Vol.111.No.05 page 101" href="http://viewer.zmags.com/publication/d54b80bd?page=101"> Discontinuation of Anti-TNF in IBD 639 Ta</a> <a title="AJG_Vol.111.No.05 page 102" href="http://viewer.zmags.com/publication/d54b80bd?page=102"> 640 Gisbert et al. Nuti et al. (43) Ramos </a> <a title="AJG_Vol.111.No.05 page 103" href="http://viewer.zmags.com/publication/d54b80bd?page=103"> subanalysis for 28–60 months after the withdrawal</a> <a title="AJG_Vol.111.No.05 page 104" href="http://viewer.zmags.com/publication/d54b80bd?page=104"> 642 Gisbert et al. REVIEW Table 5. Summary</a> <a title="AJG_Vol.111.No.05 page 105" href="http://viewer.zmags.com/publication/d54b80bd?page=105"> Discontinuation of Anti-TNF in IBD 643 </a> <a title="AJG_Vol.111.No.05 page 106" href="http://viewer.zmags.com/publication/d54b80bd?page=106"> 644 Gisbert et al. Study </a> <a title="AJG_Vol.111.No.05 page 107" href="http://viewer.zmags.com/publication/d54b80bd?page=107"> short follow-up; thus, longer studies are needed </a> <a title="AJG_Vol.111.No.05 page 108" href="http://viewer.zmags.com/publication/d54b80bd?page=108"> 646 Gisbert et al. REVIEW 10. Calafiore AC</a> <a title="AJG_Vol.111.No.05 page 109" href="http://viewer.zmags.com/publication/d54b80bd?page=109"> 55. Molnar T, Farkas K, Miheller P et al. Is the </a> <a title="AJG_Vol.111.No.05 page 110" href="http://viewer.zmags.com/publication/d54b80bd?page=110"> 648 CLINICAL AND SYSTEMATIC REVIEWS </a> <a title="AJG_Vol.111.No.05 page 111" href="http://viewer.zmags.com/publication/d54b80bd?page=111"> nature publishing group </a> <a title="AJG_Vol.111.No.05 page 112" href="http://viewer.zmags.com/publication/d54b80bd?page=112"> 650 Okafor et al. ENDOSCOPY insurance, an</a> <a title="AJG_Vol.111.No.05 page 113" href="http://viewer.zmags.com/publication/d54b80bd?page=113"> major complication (MC). As LOS can have signific</a> <a title="AJG_Vol.111.No.05 page 114" href="http://viewer.zmags.com/publication/d54b80bd?page=114"> 652 Okafor et al. ENDOSCOPY Table 1. Patie</a> <a title="AJG_Vol.111.No.05 page 115" href="http://viewer.zmags.com/publication/d54b80bd?page=115"> Hospital Inpatient Diversity and Minority Outcome</a> <a title="AJG_Vol.111.No.05 page 116" href="http://viewer.zmags.com/publication/d54b80bd?page=116"> 654 Okafor et al. ENDOSCOPY Table 3. Demog</a> <a title="AJG_Vol.111.No.05 page 117" href="http://viewer.zmags.com/publication/d54b80bd?page=117"> CONFLICT OF INTEREST Guarantor of the article: Ph</a> <a title="AJG_Vol.111.No.05 page 118" href="http://viewer.zmags.com/publication/d54b80bd?page=118"> 656 Okafor et al. ENDOSCOPY 37. Berdahl TA</a> <a title="AJG_Vol.111.No.05 page 119" href="http://viewer.zmags.com/publication/d54b80bd?page=119"> 88. Squitieri L, Reichert H, Kim HM et al. Patter</a> <a title="AJG_Vol.111.No.05 page 120" href="http://viewer.zmags.com/publication/d54b80bd?page=120"> 658 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.111.No.05 page 121" href="http://viewer.zmags.com/publication/d54b80bd?page=121"> Gestational Diabetes and NAFLD 659 asso</a> <a title="AJG_Vol.111.No.05 page 122" href="http://viewer.zmags.com/publication/d54b80bd?page=122"> 660 Ajmera et al. LIVER of hepatic steatos</a> <a title="AJG_Vol.111.No.05 page 123" href="http://viewer.zmags.com/publication/d54b80bd?page=123"> Table 2. Year 25 Characteristics of Women with On</a> <a title="AJG_Vol.111.No.05 page 124" href="http://viewer.zmags.com/publication/d54b80bd?page=124"> 662 Ajmera et al. LIVER Table 4. Multivari</a> <a title="AJG_Vol.111.No.05 page 125" href="http://viewer.zmags.com/publication/d54b80bd?page=125"> ever a previous study with 10-year follow up of w</a> <a title="AJG_Vol.111.No.05 page 126" href="http://viewer.zmags.com/publication/d54b80bd?page=126"> 664 Ajmera et al. LIVER Study Highlights </a> <a title="AJG_Vol.111.No.05 page 127" href="http://viewer.zmags.com/publication/d54b80bd?page=127"> nature publishing group </a> <a title="AJG_Vol.111.No.05 page 128" href="http://viewer.zmags.com/publication/d54b80bd?page=128"> 666 De Souza et al. LIVER abdominal viscer</a> <a title="AJG_Vol.111.No.05 page 129" href="http://viewer.zmags.com/publication/d54b80bd?page=129"> RESULTS There were 476 out of 485 women who compl</a> <a title="AJG_Vol.111.No.05 page 130" href="http://viewer.zmags.com/publication/d54b80bd?page=130"> 668 De Souza et al. LIVER Table 2. Develop</a> <a title="AJG_Vol.111.No.05 page 131" href="http://viewer.zmags.com/publication/d54b80bd?page=131"> features (5). Whether this is true in pregnancy i</a> <a title="AJG_Vol.111.No.05 page 132" href="http://viewer.zmags.com/publication/d54b80bd?page=132"> 670 De Souza et al. LIVER 11. Tiikkainen M</a> <a title="AJG_Vol.111.No.05 page 133" href="http://viewer.zmags.com/publication/d54b80bd?page=133"> nature publishing group </a> <a title="AJG_Vol.111.No.05 page 134" href="http://viewer.zmags.com/publication/d54b80bd?page=134"> 672 Corey et al. LIVER Risk Score accurate</a> <a title="AJG_Vol.111.No.05 page 135" href="http://viewer.zmags.com/publication/d54b80bd?page=135"> Table 1. Baseline characteristics Variable NA</a> <a title="AJG_Vol.111.No.05 page 136" href="http://viewer.zmags.com/publication/d54b80bd?page=136"> 674 Corey et al. </a> <a title="AJG_Vol.111.No.05 page 137" href="http://viewer.zmags.com/publication/d54b80bd?page=137"> and impaired fibrinolysis found in NASH may also </a> <a title="AJG_Vol.111.No.05 page 138" href="http://viewer.zmags.com/publication/d54b80bd?page=138"> 676 Corey et al. LIVER independent </a> <a title="AJG_Vol.111.No.05 page 139" href="http://viewer.zmags.com/publication/d54b80bd?page=139"> nature publishing group </a> <a title="AJG_Vol.111.No.05 page 140" href="http://viewer.zmags.com/publication/d54b80bd?page=140"> 678 Tapper et al. LIVER a number of reason</a> <a title="AJG_Vol.111.No.05 page 141" href="http://viewer.zmags.com/publication/d54b80bd?page=141"> allow for the determination of their NFS. In this</a> <a title="AJG_Vol.111.No.05 page 142" href="http://viewer.zmags.com/publication/d54b80bd?page=142"> 680 Tapper et al. LIVER Table 1. Demograph</a> <a title="AJG_Vol.111.No.05 page 143" href="http://viewer.zmags.com/publication/d54b80bd?page=143"> Whole cohort (n = 164) Need further</a> <a title="AJG_Vol.111.No.05 page 144" href="http://viewer.zmags.com/publication/d54b80bd?page=144"> 682 Tapper et al. LIVER Table 3. The assoc</a> <a title="AJG_Vol.111.No.05 page 145" href="http://viewer.zmags.com/publication/d54b80bd?page=145"> 33.2 kg/m2, compared with 24.4 kg/m2 in a recent </a> <a title="AJG_Vol.111.No.05 page 146" href="http://viewer.zmags.com/publication/d54b80bd?page=146"> 684 Tapper et al. LIVER 10. Petta S, Vanni</a> <a title="AJG_Vol.111.No.05 page 147" href="http://viewer.zmags.com/publication/d54b80bd?page=147"> nature publishing group </a> <a title="AJG_Vol.111.No.05 page 148" href="http://viewer.zmags.com/publication/d54b80bd?page=148"> 686 Zenlea et al. INFLAMMATORY BOWEL DISEAS</a> <a title="AJG_Vol.111.No.05 page 149" href="http://viewer.zmags.com/publication/d54b80bd?page=149"> Table 1. Characteristics of enrolled cohort at ba</a> <a title="AJG_Vol.111.No.05 page 150" href="http://viewer.zmags.com/publication/d54b80bd?page=150"> 688 Zenlea et al. INFLAMMATORY BOWEL DISEAS</a> <a title="AJG_Vol.111.No.05 page 151" href="http://viewer.zmags.com/publication/d54b80bd?page=151"> There are a number of reasons why the histolog</a> <a title="AJG_Vol.111.No.05 page 152" href="http://viewer.zmags.com/publication/d54b80bd?page=152"> 690 Zenlea et al. INFLAMMATORY BOWEL DISEAS</a> <a title="AJG_Vol.111.No.05 page 153" href="http://viewer.zmags.com/publication/d54b80bd?page=153"> nature publishing group </a> <a title="AJG_Vol.111.No.05 page 154" href="http://viewer.zmags.com/publication/d54b80bd?page=154"> 692 Negrón et al. INFLAMMATORY BOWEL DISEAS</a> <a title="AJG_Vol.111.No.05 page 155" href="http://viewer.zmags.com/publication/d54b80bd?page=155"> Alberta Health Care Insurance Plan 12</a> <a title="AJG_Vol.111.No.05 page 156" href="http://viewer.zmags.com/publication/d54b80bd?page=156"> 694 Negrón et al. INFLAMMATORY BOWEL DISEAS</a> <a title="AJG_Vol.111.No.05 page 157" href="http://viewer.zmags.com/publication/d54b80bd?page=157"> Table 3. Colectomy patients stratified by developi</a> <a title="AJG_Vol.111.No.05 page 158" href="http://viewer.zmags.com/publication/d54b80bd?page=158"> 696 Negrón et al. INFLAMMATORY BOWEL DISEAS</a> <a title="AJG_Vol.111.No.05 page 159" href="http://viewer.zmags.com/publication/d54b80bd?page=159"> REFERENCES 1. Molodecky NA, Soon IS, Rabi DM et </a> <a title="AJG_Vol.111.No.05 page 160" href="http://viewer.zmags.com/publication/d54b80bd?page=160"> 698 Negrón et al. APPENDIX 1 List of</a> <a title="AJG_Vol.111.No.05 page 161" href="http://viewer.zmags.com/publication/d54b80bd?page=161"> Ulcerative Colitis and Clostridium difficile </a> <a title="AJG_Vol.111.No.05 page 162" href="http://viewer.zmags.com/publication/d54b80bd?page=162"> 700 Negrón et al. INFLAMMATORY BOWEL DISEAS</a> <a title="AJG_Vol.111.No.05 page 163" href="http://viewer.zmags.com/publication/d54b80bd?page=163"> Ulcerative Colitis and Clostridium difficile </a> <a title="AJG_Vol.111.No.05 page 164" href="http://viewer.zmags.com/publication/d54b80bd?page=164"> 702 Negrón et al. INFLAMMATORY BOWEL DISEAS</a> <a title="AJG_Vol.111.No.05 page 165" href="http://viewer.zmags.com/publication/d54b80bd?page=165"> Ulcerative Colitis and Clostridium difficile </a> <a title="AJG_Vol.111.No.05 page 166" href="http://viewer.zmags.com/publication/d54b80bd?page=166"> 704 Negrón et al. INFLAMMATORY BOWEL DISEAS</a> <a title="AJG_Vol.111.No.05 page 167" href="http://viewer.zmags.com/publication/d54b80bd?page=167"> nature publishing group </a> <a title="AJG_Vol.111.No.05 page 168" href="http://viewer.zmags.com/publication/d54b80bd?page=168"> 706 Gulamhusein et al. INFLAMMATORY BOWEL D</a> <a title="AJG_Vol.111.No.05 page 169" href="http://viewer.zmags.com/publication/d54b80bd?page=169"> alized additive model assuming a Poisson error di</a> <a title="AJG_Vol.111.No.05 page 170" href="http://viewer.zmags.com/publication/d54b80bd?page=170"> 708 Gulamhusein et al. INFLAMMATORY BOWEL D</a> <a title="AJG_Vol.111.No.05 page 171" href="http://viewer.zmags.com/publication/d54b80bd?page=171"> with an intact colon (HR 0.67, 95% CI 0.32–1.41, </a> <a title="AJG_Vol.111.No.05 page 172" href="http://viewer.zmags.com/publication/d54b80bd?page=172"> 710 Gulamhusein et al. INFLAMMATORY BOWEL D</a> <a title="AJG_Vol.111.No.05 page 173" href="http://viewer.zmags.com/publication/d54b80bd?page=173"> REFERENCES 1. Hirschfield GM, Karlsen TH, Lindor</a> <a title="AJG_Vol.111.No.05 page 174" href="http://viewer.zmags.com/publication/d54b80bd?page=174"> 712 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.111.No.05 page 175" href="http://viewer.zmags.com/publication/d54b80bd?page=175"> Several epidemiological studies have consiste</a> <a title="AJG_Vol.111.No.05 page 176" href="http://viewer.zmags.com/publication/d54b80bd?page=176"> 714 Kabbani et al. INFLAMMATORY BOWEL DISEA</a> <a title="AJG_Vol.111.No.05 page 177" href="http://viewer.zmags.com/publication/d54b80bd?page=177"> Table 2. Relationship between baseline vitamin D </a> <a title="AJG_Vol.111.No.05 page 178" href="http://viewer.zmags.com/publication/d54b80bd?page=178"> 716 Kabbani et al. INFLAMMATORY BOWEL DISEA</a> <a title="AJG_Vol.111.No.05 page 179" href="http://viewer.zmags.com/publication/d54b80bd?page=179"> Vitamin D Levels and Clinical Status in IBD 7</a> <a title="AJG_Vol.111.No.05 page 180" href="http://viewer.zmags.com/publication/d54b80bd?page=180"> 718 Kabbani et al. R 2 = 0.9 16 14 </a> <a title="AJG_Vol.111.No.05 page 181" href="http://viewer.zmags.com/publication/d54b80bd?page=181"> acquisition of data. Miguel Regueiro: acquisition</a> <a title="AJG_Vol.111.No.05 page 182" href="http://viewer.zmags.com/publication/d54b80bd?page=182"> 720 EDITORIAL </a> <a title="AJG_Vol.111.No.05 page 183" href="http://viewer.zmags.com/publication/d54b80bd?page=183"> laboratory evidence demonstrating plausibility to</a> <a title="AJG_Vol.111.No.05 page 184" href="http://viewer.zmags.com/publication/d54b80bd?page=184"> 722 Ananthakrishnan INFLAMMATORY BOWEL DISE</a> <a title="AJG_Vol.111.No.05 page 185" href="http://viewer.zmags.com/publication/d54b80bd?page=185"> nature publishing group </a> <a title="AJG_Vol.111.No.05 page 186" href="http://viewer.zmags.com/publication/d54b80bd?page=186"> 724 Aniwan et al. COLON/SMALL BOWEL has re</a> <a title="AJG_Vol.111.No.05 page 187" href="http://viewer.zmags.com/publication/d54b80bd?page=187"> APP was calculated as the number of adenomas</a> <a title="AJG_Vol.111.No.05 page 188" href="http://viewer.zmags.com/publication/d54b80bd?page=188"> 726 Aniwan et al. COLON/SMALL BOWEL Table </a> <a title="AJG_Vol.111.No.05 page 189" href="http://viewer.zmags.com/publication/d54b80bd?page=189"> Quality Indicator for Predicting Adenoma Miss Rat</a> <a title="AJG_Vol.111.No.05 page 190" href="http://viewer.zmags.com/publication/d54b80bd?page=190"> 728 Aniwan et al. COLON/SMALL BOWEL Ne</a> <a title="AJG_Vol.111.No.05 page 191" href="http://viewer.zmags.com/publication/d54b80bd?page=191"> 13. Sankar A, Johnson SR, Beattie WS et al. Relia</a> <a title="AJG_Vol.111.No.05 page 192" href="http://viewer.zmags.com/publication/d54b80bd?page=192"> 730 EDITORIAL </a> <a title="AJG_Vol.111.No.05 page 193" href="http://viewer.zmags.com/publication/d54b80bd?page=193"> recent study, however, Shaukat and colleagues (12</a> <a title="AJG_Vol.111.No.05 page 194" href="http://viewer.zmags.com/publication/d54b80bd?page=194"> 732 Dominitz and Spiegel COLON/SMALL BOWEL </a> <a title="AJG_Vol.111.No.05 page 195" href="http://viewer.zmags.com/publication/d54b80bd?page=195"> nature publishing group </a> <a title="AJG_Vol.111.No.05 page 196" href="http://viewer.zmags.com/publication/d54b80bd?page=196"> 734 Culver et al. PANCREAS AND BILIARY TRAC</a> <a title="AJG_Vol.111.No.05 page 197" href="http://viewer.zmags.com/publication/d54b80bd?page=197"> “not IgG4-RD” if they did not meet the diagnostic</a> <a title="AJG_Vol.111.No.05 page 198" href="http://viewer.zmags.com/publication/d54b80bd?page=198"> 736 Culver et al. 2067 serum IgG4 level</a> <a title="AJG_Vol.111.No.05 page 199" href="http://viewer.zmags.com/publication/d54b80bd?page=199"> a serum IgG4 >2.8 g l-1, only 5 patients (0.5%) h</a> <a title="AJG_Vol.111.No.05 page 200" href="http://viewer.zmags.com/publication/d54b80bd?page=200"> 738 Culver et al. PANCREAS AND BILIARY TRAC</a> <a title="AJG_Vol.111.No.05 page 201" href="http://viewer.zmags.com/publication/d54b80bd?page=201"> Serum IgG4 and organ involvement in IgG4-RD The r</a> <a title="AJG_Vol.111.No.05 page 202" href="http://viewer.zmags.com/publication/d54b80bd?page=202"> 740 Culver et al. 100 10 1 Ser</a> <a title="AJG_Vol.111.No.05 page 203" href="http://viewer.zmags.com/publication/d54b80bd?page=203"> Serum IgG4 in a Prospective UK IgG4-RD Cohort </a> <a title="AJG_Vol.111.No.05 page 204" href="http://viewer.zmags.com/publication/d54b80bd?page=204"> 742 Culver et al. PANCREAS AND BILIARY TRAC</a> <a title="AJG_Vol.111.No.05 page 205" href="http://viewer.zmags.com/publication/d54b80bd?page=205"> by a NIHR Grant. E. 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