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<br /> ARCHIVE<br /> VOLUME 111 NUMBER 1 JANUARY 2016<br /> www.nature.com/ajg<br /> official publication of the american college of gastroenterology<br /> LEADING ARTICLES OF THE MONTH<br /> The Red Section: EndoTech Update<br /> 6 Just Clip It: Endoscopic Clipping in the 21st Century<br /> B. Joseph Elmunzer<br /> Practice Guidelines<br /> 30 ACG Clinical Guideline: Diagnosis and Management of Barrett’s<br /> Esophagus CME<br /> N.J. Shaheen, G.W. Falk, P.G. Iyer and L.B. Gerson<br /> Clinical and Systematic Reviews<br /> 53 Diagnosis and Management of Functional Heartburn CME<br /> C. Hachem and N.J. Shaheen<br /> Endoscopy<br /> 63 Effect of Dynamic Position Changes on Adenoma Detection during<br /> Colonoscope Withdrawal: A Randomized Controlled Multicenter Trial<br /> S.-W. Lee, J.H. Chang, J.-S. Ji et al.<br /> Liver<br /> 78 Diagnosis of Minima<a title="AJG_Vol.111.No.09 page 1" href="http://viewer.zmags.com/publication/d845c7eb?page=1"> ARCHIVE VOLUME 111 NUMBER 1 JANUARY 2016 www.nat</a> <a title="AJG_Vol.111.No.09 page 2" href="http://viewer.zmags.com/publication/d845c7eb?page=2"> VOLUME 111 NUMBER 9 SEPTEMBER 2016 www.nature.com</a> <a title="AJG_Vol.111.No.09 page 3" href="http://viewer.zmags.com/publication/d845c7eb?page=3"> CRANBERRY FLAVOR NOW AVAILABLE! </a> <a title="AJG_Vol.111.No.09 page 4" href="http://viewer.zmags.com/publication/d845c7eb?page=4"> The following is a brief summary only; see full P</a> <a title="AJG_Vol.111.No.09 page 5" href="http://viewer.zmags.com/publication/d845c7eb?page=5"> www.nature.com/ajg The American Journal o</a> <a title="AJG_Vol.111.No.09 page 6" href="http://viewer.zmags.com/publication/d845c7eb?page=6"> Patients of any HCV genotype can now be cured wit</a> <a title="AJG_Vol.111.No.09 page 7" href="http://viewer.zmags.com/publication/d845c7eb?page=7"> Albert Einstein used with permission of the HUJ/G</a> <a title="AJG_Vol.111.No.09 page 8" href="http://viewer.zmags.com/publication/d845c7eb?page=8"> NOW APPROVED THE FIRST AND ONLY PAN-GENOTYPIC ONC</a> <a title="AJG_Vol.111.No.09 page 9" href="http://viewer.zmags.com/publication/d845c7eb?page=9"> HARVONI® (ledipasvir 90 mg and sofosbuvir 400 mg)</a> <a title="AJG_Vol.111.No.09 page 10" href="http://viewer.zmags.com/publication/d845c7eb?page=10"> Brief Summary (cont.) 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Steps and ch</a> <a title="AJG_Vol.111.No.09 page 44" href="http://viewer.zmags.com/publication/d845c7eb?page=44"> THE RED SECTION 1223 see related edito</a> <a title="AJG_Vol.111.No.09 page 45" href="http://viewer.zmags.com/publication/d845c7eb?page=45"> 1224 THE RED SECTION you will know a pos</a> <a title="AJG_Vol.111.No.09 page 46" href="http://viewer.zmags.com/publication/d845c7eb?page=46"> DISCLAIMER </a> <a title="AJG_Vol.111.No.09 page 47" href="http://viewer.zmags.com/publication/d845c7eb?page=47"> 1226 THE RED SECTION Images of th</a> <a title="AJG_Vol.111.No.09 page 48" href="http://viewer.zmags.com/publication/d845c7eb?page=48"> THE RED SECTION 1227 Multicentric </a> <a title="AJG_Vol.111.No.09 page 49" href="http://viewer.zmags.com/publication/d845c7eb?page=49"> 1228 THE RED SECTION Metastatic Gastric</a> <a title="AJG_Vol.111.No.09 page 50" href="http://viewer.zmags.com/publication/d845c7eb?page=50"> THE RED SECTION 1229 Video of the Month EU</a> <a title="AJG_Vol.111.No.09 page 51" href="http://viewer.zmags.com/publication/d845c7eb?page=51"> 1230 CLINICAL AND SYSTEMATIC REVIEWS REVIEW C</a> <a title="AJG_Vol.111.No.09 page 52" href="http://viewer.zmags.com/publication/d845c7eb?page=52"> removal of precursor lesions is effective in redu</a> <a title="AJG_Vol.111.No.09 page 53" href="http://viewer.zmags.com/publication/d845c7eb?page=53"> 1232 Park et al. REVIEW Combined therapy w</a> <a title="AJG_Vol.111.No.09 page 54" href="http://viewer.zmags.com/publication/d845c7eb?page=54"> Prophylactic Therapy for Postpolypectomy Bleeding</a> <a title="AJG_Vol.111.No.09 page 55" href="http://viewer.zmags.com/publication/d845c7eb?page=55"> 1234 Park et al. Table 1. Characteristic</a> <a title="AJG_Vol.111.No.09 page 56" href="http://viewer.zmags.com/publication/d845c7eb?page=56"> Prophylactic Therapy for Postpolypectomy Bleeding</a> <a title="AJG_Vol.111.No.09 page 57" href="http://viewer.zmags.com/publication/d845c7eb?page=57"> 1236 Park et al. REVIEW mates were rated a</a> <a title="AJG_Vol.111.No.09 page 58" href="http://viewer.zmags.com/publication/d845c7eb?page=58"> disease (6,34–36,40–42). A larger polyp size is a</a> <a title="AJG_Vol.111.No.09 page 59" href="http://viewer.zmags.com/publication/d845c7eb?page=59"> 1238 Park et al. b </a> <a title="AJG_Vol.111.No.09 page 60" href="http://viewer.zmags.com/publication/d845c7eb?page=60"> Prophylactic Therapy for Postpolypectomy Bleeding</a> <a title="AJG_Vol.111.No.09 page 61" href="http://viewer.zmags.com/publication/d845c7eb?page=61"> 1240 Park et al. 100 80 60 40 P</a> <a title="AJG_Vol.111.No.09 page 62" href="http://viewer.zmags.com/publication/d845c7eb?page=62"> regarded as mechanical therapies, and hence RCTs </a> <a title="AJG_Vol.111.No.09 page 63" href="http://viewer.zmags.com/publication/d845c7eb?page=63"> 1242 Park et al. REVIEW 17. Park Y, Jeon T</a> <a title="AJG_Vol.111.No.09 page 64" href="http://viewer.zmags.com/publication/d845c7eb?page=64"> Prophylactic Therapy for Postpolypectomy Bleeding</a> <a title="AJG_Vol.111.No.09 page 65" href="http://viewer.zmags.com/publication/d845c7eb?page=65"> 1244 CLINICAL AND SYSTEMATIC REVIEWS C</a> <a title="AJG_Vol.111.No.09 page 66" href="http://viewer.zmags.com/publication/d845c7eb?page=66"> CLINICAL AND SYSTEMATIC REVIEWS 1245 C</a> <a title="AJG_Vol.111.No.09 page 67" href="http://viewer.zmags.com/publication/d845c7eb?page=67"> 1246 Ravi and Katzka ab REVIEW Distanc</a> <a title="AJG_Vol.111.No.09 page 68" href="http://viewer.zmags.com/publication/d845c7eb?page=68"> Esophageal Impedance Monitoring 1247 REVIEW </a> <a title="AJG_Vol.111.No.09 page 69" href="http://viewer.zmags.com/publication/d845c7eb?page=69"> 1248 Ravi and Katzka REVIEW with SI assess</a> <a title="AJG_Vol.111.No.09 page 70" href="http://viewer.zmags.com/publication/d845c7eb?page=70"> Esophageal Impedance Monitoring 1249 Tab</a> <a title="AJG_Vol.111.No.09 page 71" href="http://viewer.zmags.com/publication/d845c7eb?page=71"> 1250 Ravi and Katzka REVIEW Figure 4. CCPV</a> <a title="AJG_Vol.111.No.09 page 72" href="http://viewer.zmags.com/publication/d845c7eb?page=72"> impedance integral. Although the ratio of the eso</a> <a title="AJG_Vol.111.No.09 page 73" href="http://viewer.zmags.com/publication/d845c7eb?page=73"> 1252 Ravi and Katzka REVIEW Figure 5. Exam</a> <a title="AJG_Vol.111.No.09 page 74" href="http://viewer.zmags.com/publication/d845c7eb?page=74"> MUCOSAL INTEGRITY ASSESSED BY IMPEDANCE One of th</a> <a title="AJG_Vol.111.No.09 page 75" href="http://viewer.zmags.com/publication/d845c7eb?page=75"> 1254 Ravi and Katzka REVIEW that this appr</a> <a title="AJG_Vol.111.No.09 page 76" href="http://viewer.zmags.com/publication/d845c7eb?page=76"> 10. Ravi K, DeVault KR, Murray JA et al. Inter-ob</a> <a title="AJG_Vol.111.No.09 page 77" href="http://viewer.zmags.com/publication/d845c7eb?page=77"> 1256 Ravi and Katzka REVIEW 59. Cho YK, Ch</a> <a title="AJG_Vol.111.No.09 page 78" href="http://viewer.zmags.com/publication/d845c7eb?page=78"> CLINICAL AND SYSTEMATIC REVIEWS 1257 C</a> <a title="AJG_Vol.111.No.09 page 79" href="http://viewer.zmags.com/publication/d845c7eb?page=79"> CLINICAL AND SYSTEMATIC REVIEWS 125</a> <a title="AJG_Vol.111.No.09 page 80" href="http://viewer.zmags.com/publication/d845c7eb?page=80"> through chaining, by examining the bibliographies</a> <a title="AJG_Vol.111.No.09 page 81" href="http://viewer.zmags.com/publication/d845c7eb?page=81"> 1260 Hart et al. Secretin test dose (0.</a> <a title="AJG_Vol.111.No.09 page 82" href="http://viewer.zmags.com/publication/d845c7eb?page=82"> if one is interested in evaluating the pancreatic</a> <a title="AJG_Vol.111.No.09 page 83" href="http://viewer.zmags.com/publication/d845c7eb?page=83"> 1262 Hart et al. REVIEW In summary, the</a> <a title="AJG_Vol.111.No.09 page 84" href="http://viewer.zmags.com/publication/d845c7eb?page=84"> investigators have also examined the proteome of </a> <a title="AJG_Vol.111.No.09 page 85" href="http://viewer.zmags.com/publication/d845c7eb?page=85"> 1264 Hart et al. REVIEW (13,46). In a seri</a> <a title="AJG_Vol.111.No.09 page 86" href="http://viewer.zmags.com/publication/d845c7eb?page=86"> critical manuscript revisions, and approval of th</a> <a title="AJG_Vol.111.No.09 page 87" href="http://viewer.zmags.com/publication/d845c7eb?page=87"> 1266 Hart et al. REVIEW 40. Sadakari Y, Ka</a> <a title="AJG_Vol.111.No.09 page 88" href="http://viewer.zmags.com/publication/d845c7eb?page=88"> ORIGINAL CONTRIBUTIONS 1267 see related</a> <a title="AJG_Vol.111.No.09 page 89" href="http://viewer.zmags.com/publication/d845c7eb?page=89"> 1268 Reid et al. ENDOSCOPY have reported t</a> <a title="AJG_Vol.111.No.09 page 90" href="http://viewer.zmags.com/publication/d845c7eb?page=90"> endoscopy clinic scheduling software—endoPRO </a> <a title="AJG_Vol.111.No.09 page 91" href="http://viewer.zmags.com/publication/d845c7eb?page=91"> 1270 Reid et al. ENDOSCOPY Table 2. Demogr</a> <a title="AJG_Vol.111.No.09 page 92" href="http://viewer.zmags.com/publication/d845c7eb?page=92"> 120% Average percentage of clinic service utiliz</a> <a title="AJG_Vol.111.No.09 page 93" href="http://viewer.zmags.com/publication/d845c7eb?page=93"> 1272 Reid et al. ENDOSCOPY study, the no-s</a> <a title="AJG_Vol.111.No.09 page 94" href="http://viewer.zmags.com/publication/d845c7eb?page=94"> Financial support: This study was funded by a VA </a> <a title="AJG_Vol.111.No.09 page 95" href="http://viewer.zmags.com/publication/d845c7eb?page=95"> 1274 EDITORIAL see related article on </a> <a title="AJG_Vol.111.No.09 page 96" href="http://viewer.zmags.com/publication/d845c7eb?page=96"> detect day-to-day variations, morning-to-afternoo</a> <a title="AJG_Vol.111.No.09 page 97" href="http://viewer.zmags.com/publication/d845c7eb?page=97"> 1276 ORIGINAL CONTRIBUTIONS see relate</a> <a title="AJG_Vol.111.No.09 page 98" href="http://viewer.zmags.com/publication/d845c7eb?page=98"> INTRODUCTION Neuroendocrine tumors (NETs), which </a> <a title="AJG_Vol.111.No.09 page 99" href="http://viewer.zmags.com/publication/d845c7eb?page=99"> 1278 Moon et al. ENDOSCOPY Local recurrenc</a> <a title="AJG_Vol.111.No.09 page 100" href="http://viewer.zmags.com/publication/d845c7eb?page=100"> Long-Term Prognosis in Rectal Neuroendocrine Tumo</a> <a title="AJG_Vol.111.No.09 page 101" href="http://viewer.zmags.com/publication/d845c7eb?page=101"> 1280 Moon et al. ENDOSCOPY Table 1. Clinic</a> <a title="AJG_Vol.111.No.09 page 102" href="http://viewer.zmags.com/publication/d845c7eb?page=102"> Long-Term Prognosis in Rectal Neuroendocrine Tumo</a> <a title="AJG_Vol.111.No.09 page 103" href="http://viewer.zmags.com/publication/d845c7eb?page=103"> 1282 Moon et al. ENDOSCOPY Table 5. Clinic</a> <a title="AJG_Vol.111.No.09 page 104" href="http://viewer.zmags.com/publication/d845c7eb?page=104"> Long-Term Prognosis in Rectal Neuroendocrine Tumo</a> <a title="AJG_Vol.111.No.09 page 105" href="http://viewer.zmags.com/publication/d845c7eb?page=105"> 1284 Moon et al. ENDOSCOPY ACKNOWLEDGMENTS</a> <a title="AJG_Vol.111.No.09 page 106" href="http://viewer.zmags.com/publication/d845c7eb?page=106"> 31. Scherubl H, Jensen RT, Cadiot G et al. Manage</a> <a title="AJG_Vol.111.No.09 page 107" href="http://viewer.zmags.com/publication/d845c7eb?page=107"> 1286 ORIGINAL CONTRIBUTIONS LIVER INTRODUCTION</a> <a title="AJG_Vol.111.No.09 page 108" href="http://viewer.zmags.com/publication/d845c7eb?page=108"> serum qHBsAg levels can predict durability of chr</a> <a title="AJG_Vol.111.No.09 page 109" href="http://viewer.zmags.com/publication/d845c7eb?page=109"> 1288 Wang et al. LIVER Table 1. Demographi</a> <a title="AJG_Vol.111.No.09 page 110" href="http://viewer.zmags.com/publication/d845c7eb?page=110"> 50 Cumulative incidence of clinical relapse (%) </a> <a title="AJG_Vol.111.No.09 page 111" href="http://viewer.zmags.com/publication/d845c7eb?page=111"> 1290 Wang et al. LIVER Table 2. Comparison</a> <a title="AJG_Vol.111.No.09 page 112" href="http://viewer.zmags.com/publication/d845c7eb?page=112"> Overall 81 patients Clinical relapse Before 6 m</a> <a title="AJG_Vol.111.No.09 page 113" href="http://viewer.zmags.com/publication/d845c7eb?page=113"> 1292 Wang et al. a 100 Cumulative in</a> <a title="AJG_Vol.111.No.09 page 114" href="http://viewer.zmags.com/publication/d845c7eb?page=114"> Quantitative HBsAg and Durability of Entecavir-Tr</a> <a title="AJG_Vol.111.No.09 page 115" href="http://viewer.zmags.com/publication/d845c7eb?page=115"> 1294 Wang et al. LIVER Medical Foundation,</a> <a title="AJG_Vol.111.No.09 page 116" href="http://viewer.zmags.com/publication/d845c7eb?page=116"> EDITORIAL 1295 see related article on </a> <a title="AJG_Vol.111.No.09 page 117" href="http://viewer.zmags.com/publication/d845c7eb?page=117"> 1296 Pruett LIVER aminotransferase (ALT) n</a> <a title="AJG_Vol.111.No.09 page 118" href="http://viewer.zmags.com/publication/d845c7eb?page=118"> ORIGINAL CONTRIBUTIONS 1297 see relate</a> <a title="AJG_Vol.111.No.09 page 119" href="http://viewer.zmags.com/publication/d845c7eb?page=119"> 1298 Ahn et al. LIVER INTRODUCTION Hepatit</a> <a title="AJG_Vol.111.No.09 page 120" href="http://viewer.zmags.com/publication/d845c7eb?page=120"> conducted using Student's t-test or the Wilcoxon'</a> <a title="AJG_Vol.111.No.09 page 121" href="http://viewer.zmags.com/publication/d845c7eb?page=121"> 1300 Ahn et al. Hepatocellular carcinoma (%</a> <a title="AJG_Vol.111.No.09 page 122" href="http://viewer.zmags.com/publication/d845c7eb?page=122"> HCC Incidence in HBV Patients Treated With Enteca</a> <a title="AJG_Vol.111.No.09 page 123" href="http://viewer.zmags.com/publication/d845c7eb?page=123"> 1302 Ahn et al. LIVER Table 4. REACH-B est</a> <a title="AJG_Vol.111.No.09 page 124" href="http://viewer.zmags.com/publication/d845c7eb?page=124"> HCC was lower than expected in patients with CHB,</a> <a title="AJG_Vol.111.No.09 page 125" href="http://viewer.zmags.com/publication/d845c7eb?page=125"> 1304 Ahn et al. LIVER 9. Yang HI, Sherman</a> <a title="AJG_Vol.111.No.09 page 126" href="http://viewer.zmags.com/publication/d845c7eb?page=126"> ORIGINAL CONTRIBUTIONS 1305 see related</a> <a title="AJG_Vol.111.No.09 page 127" href="http://viewer.zmags.com/publication/d845c7eb?page=127"> 1306 de Lima-Karagiannis et al. INFLAMMATOR</a> <a title="AJG_Vol.111.No.09 page 128" href="http://viewer.zmags.com/publication/d845c7eb?page=128"> Effects of Active IBD During Pregnancy 1307 </a> <a title="AJG_Vol.111.No.09 page 129" href="http://viewer.zmags.com/publication/d845c7eb?page=129"> 1308 de Lima-Karagiannis et al. INFLAMMATOR</a> <a title="AJG_Vol.111.No.09 page 130" href="http://viewer.zmags.com/publication/d845c7eb?page=130"> Table 3. Congenital abnormalities, IBD medication</a> <a title="AJG_Vol.111.No.09 page 131" href="http://viewer.zmags.com/publication/d845c7eb?page=131"> 1310 de Lima-Karagiannis et al. OWEL DISEAS</a> <a title="AJG_Vol.111.No.09 page 132" href="http://viewer.zmags.com/publication/d845c7eb?page=132"> In contrast to previous studies (2,4,5,20–28)</a> <a title="AJG_Vol.111.No.09 page 133" href="http://viewer.zmags.com/publication/d845c7eb?page=133"> 1312 de Lima-Karagiannis et al. INFLAMMATOR</a> <a title="AJG_Vol.111.No.09 page 134" href="http://viewer.zmags.com/publication/d845c7eb?page=134"> ORIGINAL CONTRIBUTIONS 1313 see relate</a> <a title="AJG_Vol.111.No.09 page 135" href="http://viewer.zmags.com/publication/d845c7eb?page=135"> 1314 Wang et al. 23 million people in Ta</a> <a title="AJG_Vol.111.No.09 page 136" href="http://viewer.zmags.com/publication/d845c7eb?page=136"> till 2013) to study whether the cancer risks of C</a> <a title="AJG_Vol.111.No.09 page 137" href="http://viewer.zmags.com/publication/d845c7eb?page=137"> 1316 Wang et al. INFLAMMATORY BOWEL DISEASE</a> <a title="AJG_Vol.111.No.09 page 138" href="http://viewer.zmags.com/publication/d845c7eb?page=138"> Cancer Risk in Inflammatory Bowel Disease 131</a> <a title="AJG_Vol.111.No.09 page 139" href="http://viewer.zmags.com/publication/d845c7eb?page=139"> 1318 Wang et al. INFLAMMATORY BOWEL DISEASE</a> <a title="AJG_Vol.111.No.09 page 140" href="http://viewer.zmags.com/publication/d845c7eb?page=140"> 12. Bernstein CN, Blanchard JF, Kliewer E et al. </a> <a title="AJG_Vol.111.No.09 page 141" href="http://viewer.zmags.com/publication/d845c7eb?page=141"> 1320 ORIGINAL CONTRIBUTIONS FUNCTIONAL GI DISO</a> <a title="AJG_Vol.111.No.09 page 142" href="http://viewer.zmags.com/publication/d845c7eb?page=142"> We identified nine prospective studies, explo</a> <a title="AJG_Vol.111.No.09 page 143" href="http://viewer.zmags.com/publication/d845c7eb?page=143"> 1322 Löwe et al. FUNCTIONAL GI DISORDERS o</a> <a title="AJG_Vol.111.No.09 page 144" href="http://viewer.zmags.com/publication/d845c7eb?page=144"> In less than 5% of cases, data were missing, an</a> <a title="AJG_Vol.111.No.09 page 145" href="http://viewer.zmags.com/publication/d845c7eb?page=145"> 1324 Löwe et al. FUNCTIONAL GI DISORDERS T</a> <a title="AJG_Vol.111.No.09 page 146" href="http://viewer.zmags.com/publication/d845c7eb?page=146"> Table 2. Differences in baseline variables betwee</a> <a title="AJG_Vol.111.No.09 page 147" href="http://viewer.zmags.com/publication/d845c7eb?page=147"> 1326 Löwe et al. Odds ratios </a> <a title="AJG_Vol.111.No.09 page 148" href="http://viewer.zmags.com/publication/d845c7eb?page=148"> in both age and education, which may affect the g</a> <a title="AJG_Vol.111.No.09 page 149" href="http://viewer.zmags.com/publication/d845c7eb?page=149"> 1328 Löwe et al. FUNCTIONAL GI DISORDERS R</a> <a title="AJG_Vol.111.No.09 page 150" href="http://viewer.zmags.com/publication/d845c7eb?page=150"> 55. Layer P, Andresen V, Pehl C et al. S3-Leitlin</a> <a title="AJG_Vol.111.No.09 page 151" href="http://viewer.zmags.com/publication/d845c7eb?page=151"> 1330 ORIGINAL CONTRIBUTIONS COLON/SMALL BOWEL </a> <a title="AJG_Vol.111.No.09 page 152" href="http://viewer.zmags.com/publication/d845c7eb?page=152"> Surprisingly, there are little data regarding </a> <a title="AJG_Vol.111.No.09 page 153" href="http://viewer.zmags.com/publication/d845c7eb?page=153"> 1332 Horton et al. COLON/SMALL BOWEL Table</a> <a title="AJG_Vol.111.No.09 page 154" href="http://viewer.zmags.com/publication/d845c7eb?page=154"> 30 Single dose Split dose, first dose Split dose</a> <a title="AJG_Vol.111.No.09 page 155" href="http://viewer.zmags.com/publication/d845c7eb?page=155"> 1334 Horton et al. COLON/SMALL BOWEL Table</a> <a title="AJG_Vol.111.No.09 page 156" href="http://viewer.zmags.com/publication/d845c7eb?page=156"> Table 4. Patient travel experience and overall sa</a> <a title="AJG_Vol.111.No.09 page 157" href="http://viewer.zmags.com/publication/d845c7eb?page=157"> 1336 Horton et al. 50P < 0.001 40 </a> <a title="AJG_Vol.111.No.09 page 158" href="http://viewer.zmags.com/publication/d845c7eb?page=158"> 17. Hassan C, Bretthauer M, Kaminski MF et al. Bo</a> <a title="AJG_Vol.111.No.09 page 159" href="http://viewer.zmags.com/publication/d845c7eb?page=159"> 1338 ORIGINAL CONTRIBUTIONS CME PANCR</a> <a title="AJG_Vol.111.No.09 page 160" href="http://viewer.zmags.com/publication/d845c7eb?page=160"> ORIGINAL CONTRIBUTIONS 1339 sCeMeErelat</a> <a title="AJG_Vol.111.No.09 page 161" href="http://viewer.zmags.com/publication/d845c7eb?page=161"> 1340 Wilcox et al. PANCREAS AND BILIARY TRA</a> <a title="AJG_Vol.111.No.09 page 162" href="http://viewer.zmags.com/publication/d845c7eb?page=162"> Causes and Outcome of Idiopathic Pancreatitis </a> <a title="AJG_Vol.111.No.09 page 163" href="http://viewer.zmags.com/publication/d845c7eb?page=163"> 1342 Wilcox et al. PANCREAS AND BILIARY TRA</a> <a title="AJG_Vol.111.No.09 page 164" href="http://viewer.zmags.com/publication/d845c7eb?page=164"> Table 2. Findings during workup and attributed ca</a> <a title="AJG_Vol.111.No.09 page 165" href="http://viewer.zmags.com/publication/d845c7eb?page=165"> 1344 Wilcox et al. BILIARY TRACT PANCREAS A</a> <a title="AJG_Vol.111.No.09 page 166" href="http://viewer.zmags.com/publication/d845c7eb?page=166"> Table 5. Multivariate regression analysis of pred</a> <a title="AJG_Vol.111.No.09 page 167" href="http://viewer.zmags.com/publication/d845c7eb?page=167"> 1346 Wilcox et al. PANCREAS AND BILIARY TRA</a> <a title="AJG_Vol.111.No.09 page 168" href="http://viewer.zmags.com/publication/d845c7eb?page=168"> Study Highlights WHAT IS CURRENT KNOWLEDGE ✓ Des</a> <a title="AJG_Vol.111.No.09 page 169" href="http://viewer.zmags.com/publication/d845c7eb?page=169"> 1348 Wilcox et al. PANCREAS AND BILIARY TRA</a> <a title="AJG_Vol.111.No.09 page 170" href="http://viewer.zmags.com/publication/d845c7eb?page=170"> ORIGINAL CONTRIBUTIONS 1349 CME Con</a> <a title="AJG_Vol.111.No.09 page 171" href="http://viewer.zmags.com/publication/d845c7eb?page=171"> 1350 ORIGINAL CONTRIBUTIONS see relate</a> <a title="AJG_Vol.111.No.09 page 172" href="http://viewer.zmags.com/publication/d845c7eb?page=172"> colon, liver, breast, and lung (3–9). Furthermore</a> <a title="AJG_Vol.111.No.09 page 173" href="http://viewer.zmags.com/publication/d845c7eb?page=173"> 1352 Amin et al. PANCREAS AND BILIARY TRACT</a> <a title="AJG_Vol.111.No.09 page 174" href="http://viewer.zmags.com/publication/d845c7eb?page=174"> Table 2. Tumor and treatment characteristics of d</a> <a title="AJG_Vol.111.No.09 page 175" href="http://viewer.zmags.com/publication/d845c7eb?page=175"> 1354 Amin et al. a 1.0 0.8 0.6 0.</a> <a title="AJG_Vol.111.No.09 page 176" href="http://viewer.zmags.com/publication/d845c7eb?page=176"> and those who were on metformin for >2 years befo</a> <a title="AJG_Vol.111.No.09 page 177" href="http://viewer.zmags.com/publication/d845c7eb?page=177"> 1356 Amin et al. PANCREAS AND BILIARY TRACT</a> <a title="AJG_Vol.111.No.09 page 178" href="http://viewer.zmags.com/publication/d845c7eb?page=178"> 19. Hebert PL, Geiss LS, Tierney EF et al. 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