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<br /> ARCHIVE<br /> VOLUME 110 NUMBER 1 JANUARY 2015<br /> www.amjgastro.com<br /> OFFICIAL PUBLICATION OF THE AMERICAN COLLEGE OF GASTROENTEROLOGY<br /> LEADING ARTICLES OF THE MONTH<br /> Practice Guidelines<br /> 18 ACG Clinical Guidelines: Epidemiology, Risk Factors,<br /> Patterns of Presentation, Diagnosis, and Management<br /> of Colon Ischemia (CI) CME<br /> L.J. Brandt, P. Feuerstadt, G.F. Longstreth and S.J. Boley<br /> Quality Indicators for GI Endoscopic Procedures<br /> 60 Quality Indicators for EGD<br /> W.G. Park, N.J. Shaheen, J. Cohen, I.M. Pike, D.G. Adler, J.M. Inadomi,<br /> L.A. Laine, J.G. Lieb II, M.K. Rizk, M.S. Sawhney and S. Wani<br /> 72 Quality Indicators for Colonoscopy<br /> D.K. Rex, P.S. Schoenfeld, J. Cohen, I.M. Pike, D.G. Adler, M.B. Fennerty,<br /> J.G. Lieb II, W.G. Park, M.K. Rizk, M.S. Sawhney, N.J. 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Randomized cont</a> <a title="AJG_Vol.110.No.2 page 43" href="http://viewer.zmags.com/publication/e096dcaa?page=43"> 212 THE RED SECTION medical marijuana to t</a> <a title="AJG_Vol.110.No.2 page 44" href="http://viewer.zmags.com/publication/e096dcaa?page=44"> 11. Matsuda LA, Lolait SJ, Brownstein MJ et al. S</a> <a title="AJG_Vol.110.No.2 page 45" href="http://viewer.zmags.com/publication/e096dcaa?page=45"> 214 THE RED SECTION 65. Brisbois TD, de Koc</a> <a title="AJG_Vol.110.No.2 page 46" href="http://viewer.zmags.com/publication/e096dcaa?page=46"> nature publishing group </a> <a title="AJG_Vol.110.No.2 page 47" href="http://viewer.zmags.com/publication/e096dcaa?page=47"> 216 THE RED SECTION Methods Study populati</a> <a title="AJG_Vol.110.No.2 page 48" href="http://viewer.zmags.com/publication/e096dcaa?page=48"> Newspapers/magazines 5% Other Family member </a> <a title="AJG_Vol.110.No.2 page 49" href="http://viewer.zmags.com/publication/e096dcaa?page=49"> metrics to guide patients to higher-value provide</a> <a title="AJG_Vol.110.No.2 page 50" href="http://viewer.zmags.com/publication/e096dcaa?page=50"> CONFLICT OF INTEREST Guarantor of the article: Ha</a> <a title="AJG_Vol.110.No.2 page 51" href="http://viewer.zmags.com/publication/e096dcaa?page=51"> 220 THE RED SECTION </a> <a title="AJG_Vol.110.No.2 page 52" href="http://viewer.zmags.com/publication/e096dcaa?page=52"> nature publishing group </a> <a title="AJG_Vol.110.No.2 page 53" href="http://viewer.zmags.com/publication/e096dcaa?page=53"> 222 PRACTICE GUIDELINES </a> <a title="AJG_Vol.110.No.2 page 54" href="http://viewer.zmags.com/publication/e096dcaa?page=54"> nature publishing group </a> <a title="AJG_Vol.110.No.2 page 55" href="http://viewer.zmags.com/publication/e096dcaa?page=55"> 224 Syngal et al. Table 1. Summary stateme</a> <a title="AJG_Vol.110.No.2 page 56" href="http://viewer.zmags.com/publication/e096dcaa?page=56"> Hereditary GI Cancer Syndromes 225 Table 2.</a> <a title="AJG_Vol.110.No.2 page 57" href="http://viewer.zmags.com/publication/e096dcaa?page=57"> 226 Syngal et al. Table 2. Continued Se</a> <a title="AJG_Vol.110.No.2 page 58" href="http://viewer.zmags.com/publication/e096dcaa?page=58"> vention clearly outweigh the undesirable effects </a> <a title="AJG_Vol.110.No.2 page 59" href="http://viewer.zmags.com/publication/e096dcaa?page=59"> 228 Syngal et al. Summary of evidence LS,</a> <a title="AJG_Vol.110.No.2 page 60" href="http://viewer.zmags.com/publication/e096dcaa?page=60"> Hereditary GI Cancer Syndromes 229 Table 4.</a> <a title="AJG_Vol.110.No.2 page 61" href="http://viewer.zmags.com/publication/e096dcaa?page=61"> 230 Syngal et al. Table 5. Cumulative risk</a> <a title="AJG_Vol.110.No.2 page 62" href="http://viewer.zmags.com/publication/e096dcaa?page=62"> Hereditary GI Cancer Syndromes 231 Table 6.</a> <a title="AJG_Vol.110.No.2 page 63" href="http://viewer.zmags.com/publication/e096dcaa?page=63"> 232 Syngal et al. Table 6. Studies of colo</a> <a title="AJG_Vol.110.No.2 page 64" href="http://viewer.zmags.com/publication/e096dcaa?page=64"> Hereditary GI Cancer Syndromes 233 Table 7.</a> <a title="AJG_Vol.110.No.2 page 65" href="http://viewer.zmags.com/publication/e096dcaa?page=65"> 234 Syngal et al. Table 7. Continued Cance</a> <a title="AJG_Vol.110.No.2 page 66" href="http://viewer.zmags.com/publication/e096dcaa?page=66"> Hereditary GI Cancer Syndromes 235 Table 8.</a> <a title="AJG_Vol.110.No.2 page 67" href="http://viewer.zmags.com/publication/e096dcaa?page=67"> 236 Syngal et al. Table 8. Continued Organ</a> <a title="AJG_Vol.110.No.2 page 68" href="http://viewer.zmags.com/publication/e096dcaa?page=68"> Summary of evidence There are three known heredit</a> <a title="AJG_Vol.110.No.2 page 69" href="http://viewer.zmags.com/publication/e096dcaa?page=69"> 238 Syngal et al. Monoallelic MUTYH mut</a> <a title="AJG_Vol.110.No.2 page 70" href="http://viewer.zmags.com/publication/e096dcaa?page=70"> mal colonic polyp distribution. Onset of examinat</a> <a title="AJG_Vol.110.No.2 page 71" href="http://viewer.zmags.com/publication/e096dcaa?page=71"> 240 Syngal et al. Table 9. Duodenal adenom</a> <a title="AJG_Vol.110.No.2 page 72" href="http://viewer.zmags.com/publication/e096dcaa?page=72"> Upper GI screening has not been demonstrated to</a> <a title="AJG_Vol.110.No.2 page 73" href="http://viewer.zmags.com/publication/e096dcaa?page=73"> 242 Syngal et al. >20 adenomas) is treate</a> <a title="AJG_Vol.110.No.2 page 74" href="http://viewer.zmags.com/publication/e096dcaa?page=74"> Hereditary GI Cancer Syndromes 243 Table 10</a> <a title="AJG_Vol.110.No.2 page 75" href="http://viewer.zmags.com/publication/e096dcaa?page=75"> 244 Syngal et al. Table 10. Continued Site</a> <a title="AJG_Vol.110.No.2 page 76" href="http://viewer.zmags.com/publication/e096dcaa?page=76"> Treatment involves EGD and colonoscopic removal</a> <a title="AJG_Vol.110.No.2 page 77" href="http://viewer.zmags.com/publication/e096dcaa?page=77"> 246 Syngal et al. cancers (strong recom</a> <a title="AJG_Vol.110.No.2 page 78" href="http://viewer.zmags.com/publication/e096dcaa?page=78"> Hereditary GI Cancer Syndromes 247 Table 11</a> <a title="AJG_Vol.110.No.2 page 79" href="http://viewer.zmags.com/publication/e096dcaa?page=79"> 248 Syngal et al. uterine, kidney, and ski</a> <a title="AJG_Vol.110.No.2 page 80" href="http://viewer.zmags.com/publication/e096dcaa?page=80"> Although the mechanisms are not entirely clear</a> <a title="AJG_Vol.110.No.2 page 81" href="http://viewer.zmags.com/publication/e096dcaa?page=81"> 250 Syngal et al. frequency and age of in</a> <a title="AJG_Vol.110.No.2 page 82" href="http://viewer.zmags.com/publication/e096dcaa?page=82"> suggest that up to 10% of PC patients will have a</a> <a title="AJG_Vol.110.No.2 page 83" href="http://viewer.zmags.com/publication/e096dcaa?page=83"> 252 Syngal et al. sized the importance of</a> <a title="AJG_Vol.110.No.2 page 84" href="http://viewer.zmags.com/publication/e096dcaa?page=84"> mutations are large rearrangements) (305). Betwee</a> <a title="AJG_Vol.110.No.2 page 85" href="http://viewer.zmags.com/publication/e096dcaa?page=85"> 254 Syngal et al. Informed consent Geneti</a> <a title="AJG_Vol.110.No.2 page 86" href="http://viewer.zmags.com/publication/e096dcaa?page=86"> Cancer Network, Inc 2014. All rights res</a> <a title="AJG_Vol.110.No.2 page 87" href="http://viewer.zmags.com/publication/e096dcaa?page=87"> 256 Syngal et al. 50. Parry S, Win AK, Pa</a> <a title="AJG_Vol.110.No.2 page 88" href="http://viewer.zmags.com/publication/e096dcaa?page=88"> 100. Nagase H, Nakamura Y. Mutations of the APC (</a> <a title="AJG_Vol.110.No.2 page 89" href="http://viewer.zmags.com/publication/e096dcaa?page=89"> 258 Syngal et al. 150. Tulchinsky H, Keida</a> <a title="AJG_Vol.110.No.2 page 90" href="http://viewer.zmags.com/publication/e096dcaa?page=90"> 201. Amaro R, Diaz G, Schneider J et al. Peutz-Je</a> <a title="AJG_Vol.110.No.2 page 91" href="http://viewer.zmags.com/publication/e096dcaa?page=91"> 260 Syngal et al. 253. Boparai KS, Mathus-</a> <a title="AJG_Vol.110.No.2 page 92" href="http://viewer.zmags.com/publication/e096dcaa?page=92"> 305. Seevaratnam R, Coburn N, Cardoso R et al. A </a> <a title="AJG_Vol.110.No.2 page 93" href="http://viewer.zmags.com/publication/e096dcaa?page=93"> 262 Syngal et al. patients with P</a> <a title="AJG_Vol.110.No.2 page 94" href="http://viewer.zmags.com/publication/e096dcaa?page=94"> nature publishing group </a> <a title="AJG_Vol.110.No.2 page 95" href="http://viewer.zmags.com/publication/e096dcaa?page=95"> 264 CLINICAL AND SYSTEMATIC REVIEWS </a> <a title="AJG_Vol.110.No.2 page 96" href="http://viewer.zmags.com/publication/e096dcaa?page=96"> nature publishing group </a> <a title="AJG_Vol.110.No.2 page 97" href="http://viewer.zmags.com/publication/e096dcaa?page=97"> 266 Tong et al. REVIEW Furthermore, an incr</a> <a title="AJG_Vol.110.No.2 page 98" href="http://viewer.zmags.com/publication/e096dcaa?page=98"> 1,972 Potentially relevant articles ident</a> <a title="AJG_Vol.110.No.2 page 99" href="http://viewer.zmags.com/publication/e096dcaa?page=99"> 268 Tong et al. Table 1. Characteristics of </a> <a title="AJG_Vol.110.No.2 page 100" href="http://viewer.zmags.com/publication/e096dcaa?page=100"> Incidence of Microscopic Colitis 269 Table </a> <a title="AJG_Vol.110.No.2 page 101" href="http://viewer.zmags.com/publication/e096dcaa?page=101"> 270 Tong et al. Author (year) </a> <a title="AJG_Vol.110.No.2 page 102" href="http://viewer.zmags.com/publication/e096dcaa?page=102"> Incidence of Microscopic Colitis 271 REVIEW </a> <a title="AJG_Vol.110.No.2 page 103" href="http://viewer.zmags.com/publication/e096dcaa?page=103"> 272 Tong et al. Author (year) </a> <a title="AJG_Vol.110.No.2 page 104" href="http://viewer.zmags.com/publication/e096dcaa?page=104"> Incidence of Microscopic Colitis 273 Table </a> <a title="AJG_Vol.110.No.2 page 105" href="http://viewer.zmags.com/publication/e096dcaa?page=105"> 274 Tong et al. 20 per 100,000 populati</a> <a title="AJG_Vol.110.No.2 page 106" href="http://viewer.zmags.com/publication/e096dcaa?page=106"> incidence of CC and LC. In fact, the incidence se</a> <a title="AJG_Vol.110.No.2 page 107" href="http://viewer.zmags.com/publication/e096dcaa?page=107"> 276 Tong et al. REVIEW 4. Agnarsdottir M, </a> <a title="AJG_Vol.110.No.2 page 108" href="http://viewer.zmags.com/publication/e096dcaa?page=108"> nature publishing group </a> <a title="AJG_Vol.110.No.2 page 109" href="http://viewer.zmags.com/publication/e096dcaa?page=109"> CLINICAL AND SYSTEMATIC REVIEWS 278 </a> <a title="AJG_Vol.110.No.2 page 110" href="http://viewer.zmags.com/publication/e096dcaa?page=110"> THE IMPACT OF DIET ON THE INTESTINAL MICROBIOTA T</a> <a title="AJG_Vol.110.No.2 page 111" href="http://viewer.zmags.com/publication/e096dcaa?page=111"> 280 Rajilić-Stojanović et al REVIEW reporte</a> <a title="AJG_Vol.110.No.2 page 112" href="http://viewer.zmags.com/publication/e096dcaa?page=112"> Actinobacteria Bifidobacteriaceae Bifidobacterium</a> <a title="AJG_Vol.110.No.2 page 113" href="http://viewer.zmags.com/publication/e096dcaa?page=113"> 282 Rajilić-Stojanović et al REVIEW have su</a> <a title="AJG_Vol.110.No.2 page 114" href="http://viewer.zmags.com/publication/e096dcaa?page=114"> Diet  Carbohydrates (e.g., FODMAPs, starch</a> <a title="AJG_Vol.110.No.2 page 115" href="http://viewer.zmags.com/publication/e096dcaa?page=115"> 284 Rajilić-Stojanović et al REVIEW patient</a> <a title="AJG_Vol.110.No.2 page 116" href="http://viewer.zmags.com/publication/e096dcaa?page=116"> 8. Jeffery IB, O’Toole PW, Öhman L et al. An ir</a> <a title="AJG_Vol.110.No.2 page 117" href="http://viewer.zmags.com/publication/e096dcaa?page=117"> 286 Rajilić-Stojanović et al REVIEW 61. Ha</a> <a title="AJG_Vol.110.No.2 page 118" href="http://viewer.zmags.com/publication/e096dcaa?page=118"> 112. Pritchard SE, Marciani L, Garsed KC et al. F</a> <a title="AJG_Vol.110.No.2 page 119" href="http://viewer.zmags.com/publication/e096dcaa?page=119"> 288 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.110.No.2 page 120" href="http://viewer.zmags.com/publication/e096dcaa?page=120"> CRC, predominantly in the proximal colon (2–6). A</a> <a title="AJG_Vol.110.No.2 page 121" href="http://viewer.zmags.com/publication/e096dcaa?page=121"> 290 Rahmi et al. ENDOSCOPY Chromoendoscopy </a> <a title="AJG_Vol.110.No.2 page 122" href="http://viewer.zmags.com/publication/e096dcaa?page=122"> Chromocolonoscopy in Lynch Syndrome 291 8</a> <a title="AJG_Vol.110.No.2 page 123" href="http://viewer.zmags.com/publication/e096dcaa?page=123"> 292 Rahmi et al. ENDOSCOPY Table 2. Charact</a> <a title="AJG_Vol.110.No.2 page 124" href="http://viewer.zmags.com/publication/e096dcaa?page=124"> Chromocolonoscopy in Lynch Syndrome 293 7</a> <a title="AJG_Vol.110.No.2 page 125" href="http://viewer.zmags.com/publication/e096dcaa?page=125"> 294 Rahmi et al. ENDOSCOPY Table 3. Compari</a> <a title="AJG_Vol.110.No.2 page 126" href="http://viewer.zmags.com/publication/e096dcaa?page=126"> Chromocolonoscopy in Lynch Syndrome 295 Tab</a> <a title="AJG_Vol.110.No.2 page 127" href="http://viewer.zmags.com/publication/e096dcaa?page=127"> 296 Rahmi et al. ENDOSCOPY tion of patients</a> <a title="AJG_Vol.110.No.2 page 128" href="http://viewer.zmags.com/publication/e096dcaa?page=128"> CONFLICT OF INTEREST Guarantor of the article: Ch</a> <a title="AJG_Vol.110.No.2 page 129" href="http://viewer.zmags.com/publication/e096dcaa?page=129"> 298 Rahmi et al. ENDOSCOPY 34. Hüneburg R, </a> <a title="AJG_Vol.110.No.2 page 130" href="http://viewer.zmags.com/publication/e096dcaa?page=130"> nature publishing group </a> <a title="AJG_Vol.110.No.2 page 131" href="http://viewer.zmags.com/publication/e096dcaa?page=131"> 300 Eaton et al. LIVER highly variable appe</a> <a title="AJG_Vol.110.No.2 page 132" href="http://viewer.zmags.com/publication/e096dcaa?page=132"> CEP 3 CEP 7 CEP 17 9p21 </a> <a title="AJG_Vol.110.No.2 page 133" href="http://viewer.zmags.com/publication/e096dcaa?page=133"> 302 Eaton et al. PSC patients with FISH t</a> <a title="AJG_Vol.110.No.2 page 134" href="http://viewer.zmags.com/publication/e096dcaa?page=134"> Biliary MFP and CCA in PSC Patients 303 Tab</a> <a title="AJG_Vol.110.No.2 page 135" href="http://viewer.zmags.com/publication/e096dcaa?page=135"> 304 Eaton et al. LIVER Table 2. Baseline fe</a> <a title="AJG_Vol.110.No.2 page 136" href="http://viewer.zmags.com/publication/e096dcaa?page=136"> CCA after adjustment for FISH (HR, 5.72; 95% CI, </a> <a title="AJG_Vol.110.No.2 page 137" href="http://viewer.zmags.com/publication/e096dcaa?page=137"> 306 Eaton et al. 1.0 0.8 0.6 LIVE</a> <a title="AJG_Vol.110.No.2 page 138" href="http://viewer.zmags.com/publication/e096dcaa?page=138"> Biliary MFP and CCA in PSC Patients 307 Tab</a> <a title="AJG_Vol.110.No.2 page 139" href="http://viewer.zmags.com/publication/e096dcaa?page=139"> 308 Eaton et al. Univariate FISH resu</a> <a title="AJG_Vol.110.No.2 page 140" href="http://viewer.zmags.com/publication/e096dcaa?page=140"> 17. Kamath PS, Kim WR. The model for end-stage li</a> <a title="AJG_Vol.110.No.2 page 141" href="http://viewer.zmags.com/publication/e096dcaa?page=141"> 310 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.110.No.2 page 142" href="http://viewer.zmags.com/publication/e096dcaa?page=142"> orders such as diabetes, hyperlipidemia, hyperten</a> <a title="AJG_Vol.110.No.2 page 143" href="http://viewer.zmags.com/publication/e096dcaa?page=143"> 312 Lee et al. 10 </a> <a title="AJG_Vol.110.No.2 page 144" href="http://viewer.zmags.com/publication/e096dcaa?page=144"> Visceral Adiposity and Irritable Bowel Syndrome </a> <a title="AJG_Vol.110.No.2 page 145" href="http://viewer.zmags.com/publication/e096dcaa?page=145"> 314 Lee et al. GI DISORDERS FUNCTIONAL Tabl</a> <a title="AJG_Vol.110.No.2 page 146" href="http://viewer.zmags.com/publication/e096dcaa?page=146"> Visceral Adiposity and Irritable Bowel Syndrome </a> <a title="AJG_Vol.110.No.2 page 147" href="http://viewer.zmags.com/publication/e096dcaa?page=147"> 316 Lee et al. GI DISORDERS FUNCTIONAL Tabl</a> <a title="AJG_Vol.110.No.2 page 148" href="http://viewer.zmags.com/publication/e096dcaa?page=148"> Visceral adiposity Mechanical effect Metabolic ef</a> <a title="AJG_Vol.110.No.2 page 149" href="http://viewer.zmags.com/publication/e096dcaa?page=149"> 318 Lee et al. FUNCTIONAL GI DISORDERS diag</a> <a title="AJG_Vol.110.No.2 page 150" href="http://viewer.zmags.com/publication/e096dcaa?page=150"> 27. Simren M, Castedal M, Svedlund J et al. Abnor</a> <a title="AJG_Vol.110.No.2 page 151" href="http://viewer.zmags.com/publication/e096dcaa?page=151"> 320 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.110.No.2 page 152" href="http://viewer.zmags.com/publication/e096dcaa?page=152"> Chronic Norovirus Infection in CVID Enteropathy </a> <a title="AJG_Vol.110.No.2 page 153" href="http://viewer.zmags.com/publication/e096dcaa?page=153"> 322 Woodward et al. COLON/SMALL BOWEL Table</a> <a title="AJG_Vol.110.No.2 page 154" href="http://viewer.zmags.com/publication/e096dcaa?page=154"> Chronic Norovirus Infection in CVID Enteropathy </a> <a title="AJG_Vol.110.No.2 page 155" href="http://viewer.zmags.com/publication/e096dcaa?page=155"> 324 Woodward et al. gested that the same </a> <a title="AJG_Vol.110.No.2 page 156" href="http://viewer.zmags.com/publication/e096dcaa?page=156"> Chronic Norovirus Infection in CVID Enteropathy </a> <a title="AJG_Vol.110.No.2 page 157" href="http://viewer.zmags.com/publication/e096dcaa?page=157"> 326 Woodward et al. COLON/SMALL BOWEL in im</a> <a title="AJG_Vol.110.No.2 page 158" href="http://viewer.zmags.com/publication/e096dcaa?page=158"> 16. Castigli E, Geha RS. TACI, isotype switching,</a> <a title="AJG_Vol.110.No.2 page 159" href="http://viewer.zmags.com/publication/e096dcaa?page=159"> 328 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.110.No.2 page 160" href="http://viewer.zmags.com/publication/e096dcaa?page=160"> Chest Physicians recommends rapid reversal of ant</a> <a title="AJG_Vol.110.No.2 page 161" href="http://viewer.zmags.com/publication/e096dcaa?page=161"> 330 Sengupta et al. COLON/SMALL BOWEL varia</a> <a title="AJG_Vol.110.No.2 page 162" href="http://viewer.zmags.com/publication/e096dcaa?page=162"> Anticoagulation Management Following GI Bleeding </a> <a title="AJG_Vol.110.No.2 page 163" href="http://viewer.zmags.com/publication/e096dcaa?page=163"> 332 Sengupta et al. COLON/SMALL BOWEL Table</a> <a title="AJG_Vol.110.No.2 page 164" href="http://viewer.zmags.com/publication/e096dcaa?page=164"> Anticoagulation Management Following GI Bleeding </a> <a title="AJG_Vol.110.No.2 page 165" href="http://viewer.zmags.com/publication/e096dcaa?page=165"> 0 10 20 30 40 </a> <a title="AJG_Vol.110.No.2 page 166" href="http://viewer.zmags.com/publication/e096dcaa?page=166"> CONFLICT OF INTEREST Guarantor of the article: N.</a> <a title="AJG_Vol.110.No.2 page 167" href="http://viewer.zmags.com/publication/e096dcaa?page=167"> 336 ORIGINAL CONTRIBUTIONS </a> <a title="AJG_Vol.110.No.2 page 168" href="http://viewer.zmags.com/publication/e096dcaa?page=168"> susceptibility to fracture (2). Osteoporosis also</a> <a title="AJG_Vol.110.No.2 page 169" href="http://viewer.zmags.com/publication/e096dcaa?page=169"> 338 Duggan et al. PANCREAS AND BILIARY TRACT</a> <a title="AJG_Vol.110.No.2 page 170" href="http://viewer.zmags.com/publication/e096dcaa?page=170"> Table 1. Demographic details for patients and con</a> <a title="AJG_Vol.110.No.2 page 171" href="http://viewer.zmags.com/publication/e096dcaa?page=171"> 340 Duggan et al. PANCREAS AND BILIARY TRACT</a> <a title="AJG_Vol.110.No.2 page 172" href="http://viewer.zmags.com/publication/e096dcaa?page=172"> 160 140 120 PINP (µg/l) 100 80 60 40 P = </a> <a title="AJG_Vol.110.No.2 page 173" href="http://viewer.zmags.com/publication/e096dcaa?page=173"> 342 Duggan et al. PANCREAS AND BILIARY TRACT</a> <a title="AJG_Vol.110.No.2 page 174" href="http://viewer.zmags.com/publication/e096dcaa?page=174"> Table 4. Multiple (linear) regression showing fac</a> <a title="AJG_Vol.110.No.2 page 175" href="http://viewer.zmags.com/publication/e096dcaa?page=175"> 344 Duggan et al. PANCREAS AND BILIARY TRACT</a> <a title="AJG_Vol.110.No.2 page 176" href="http://viewer.zmags.com/publication/e096dcaa?page=176"> 13. Vasikaran S, Eastell R, Bruyere O et al. 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