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<br /> STRAP<br /> <br /> Copyright © 2010 Quintiles<br /> <br /> leverages more brainpower.<br /> <br /> <br /> <br /> <br /> <br /> <br /> <br /> <br /> <br /> <br /> <br /> <br /> <br /> <br /> <br /> No one develops a drug alone. Or restructures<br /> a business model. Or finds capital for a<br /> promising biologic. Today, biopharma needs<br /> new ideas and new teammates, thinkers and<br /> doers. In the fast-morphing world of<br /> the New Health, we’re a steady ally.<br /> More at www.quintiles.com/newhealth<br /> <br /> <br /> <br /> <br /> <br /> <br /> <br /> <br /> clinical | commercial | consulting | capital<br /> <br /> 77 www.pharma-mag.com <a title="Pharma Nov/Dec 2010 page 1" href="http://viewer.zmags.com/publication/e9f19faa?page=1">STRAPCopyright © 2010 Quintilesleverages more</a> STRAPCopyright © 2010 Quintilesleverages more<a title="Pharma Nov/Dec 2010 page 2" href="http://viewer.zmags.com/publication/e9f19faa?page=2">www.pharma-mag.comNovember/December 2010 ISSN 1</a> www.pharma-mag.comNovember/December 2010 ISSN 1<a title="Pharma Nov/Dec 2010 page 3" href="http://viewer.zmags.com/publication/e9f19faa?page=3">STRAPOur comfort zone is here:</a> STRAPOur comfort zone is here:<a title="Pharma Nov/Dec 2010 page 4" href="http://viewer.zmags.com/publication/e9f19faa?page=4">CONTENTSFor up-to-date news follow us on Twitte</a> CONTENTSFor up-to-date news follow us on Twitte<a title="Pharma Nov/Dec 2010 page 5" href="http://viewer.zmags.com/publication/e9f19faa?page=5">FROM THE EDITOReditorCorrine Lawrence+44 (0)</a> FROM THE EDITOReditorCorrine Lawrence+44 (0)<a title="Pharma Nov/Dec 2010 page 6" href="http://viewer.zmags.com/publication/e9f19faa?page=6">COMMENTWhaT PrICeBureauCRACY?2health’s Project</a> COMMENTWhaT PrICeBureauCRACY?2health’s Project<a title="Pharma Nov/Dec 2010 page 7" href="http://viewer.zmags.com/publication/e9f19faa?page=7">EOA REVIEWThe extraordinary l</a> EOA REVIEWThe extraordinary l<a title="Pharma Nov/Dec 2010 page 8" href="http://viewer.zmags.com/publication/e9f19faa?page=8">EOA REVIEWW And Theinners Are ...The quality</a> EOA REVIEWW And Theinners Are ...The quality<a title="Pharma Nov/Dec 2010 page 9" href="http://viewer.zmags.com/publication/e9f19faa?page=9">EOA REVIEWMost Improved Process/Plan</a> EOA REVIEWMost Improved Process/Plan<a title="Pharma Nov/Dec 2010 page 10" href="http://viewer.zmags.com/publication/e9f19faa?page=10">EOA REVIEWPatheon offers to eliminate uP-front t</a> EOA REVIEWPatheon offers to eliminate uP-front t<a title="Pharma Nov/Dec 2010 page 11" href="http://viewer.zmags.com/publication/e9f19faa?page=11">EOA REVIEWThe winningproject representeda tru</a> EOA REVIEWThe winningproject representeda tru<a title="Pharma Nov/Dec 2010 page 12" href="http://viewer.zmags.com/publication/e9f19faa?page=12">EOA REVIEWtrials and challenging the</a> EOA REVIEWtrials and challenging the<a title="Pharma Nov/Dec 2010 page 13" href="http://viewer.zmags.com/publication/e9f19faa?page=13">EOA REVIEWBest Contract Analytical P</a> EOA REVIEWBest Contract Analytical P<a title="Pharma Nov/Dec 2010 page 14" href="http://viewer.zmags.com/publication/e9f19faa?page=14">EOA REVIEW“Shift mywareh use intohi h gear.”</a> EOA REVIEW“Shift mywareh use intohi h gear.”<a title="Pharma Nov/Dec 2010 page 15" href="http://viewer.zmags.com/publication/e9f19faa?page=15">EOA REVIEWBest Contract Manufacturing Project </a> EOA REVIEWBest Contract Manufacturing Project <a title="Pharma Nov/Dec 2010 page 16" href="http://viewer.zmags.com/publication/e9f19faa?page=16">EOA REVIEWmore products.better treatments.r</a> EOA REVIEWmore products.better treatments.r<a title="Pharma Nov/Dec 2010 page 17" href="http://viewer.zmags.com/publication/e9f19faa?page=17">EOA REVIEWBest e-Business or IT Strate</a> EOA REVIEWBest e-Business or IT Strate<a title="Pharma Nov/Dec 2010 page 18" href="http://viewer.zmags.com/publication/e9f19faa?page=18">EOA REVIEWJourney with DSMDSM of</a> EOA REVIEWJourney with DSMDSM of<a title="Pharma Nov/Dec 2010 page 19" href="http://viewer.zmags.com/publication/e9f19faa?page=19">EOA REVIEWBest New Product — Indena SpA</a> EOA REVIEWBest New Product — Indena SpA<a title="Pharma Nov/Dec 2010 page 20" href="http://viewer.zmags.com/publication/e9f19faa?page=20">EOA REVIEWWE’LL ALWAYS BE… CLOSE TO YOU</a> EOA REVIEWWE’LL ALWAYS BE… CLOSE TO YOU<a title="Pharma Nov/Dec 2010 page 21" href="http://viewer.zmags.com/publication/e9f19faa?page=21">EOA REVIEWAdditionAl EoA SponSorSgr</a> EOA REVIEWAdditionAl EoA SponSorSgr<a title="Pharma Nov/Dec 2010 page 22" href="http://viewer.zmags.com/publication/e9f19faa?page=22">EOA REVIEW</a> EOA REVIEW<a title="Pharma Nov/Dec 2010 page 23" href="http://viewer.zmags.com/publication/e9f19faa?page=23">SOLID DOSAGEThe shaPeoF ThIngsTo CoMePaul Ti</a> SOLID DOSAGEThe shaPeoF ThIngsTo CoMePaul Ti<a title="Pharma Nov/Dec 2010 page 24" href="http://viewer.zmags.com/publication/e9f19faa?page=24">SOLID DOSAGEa change in dose or concentration,</a> SOLID DOSAGEa change in dose or concentration,<a title="Pharma Nov/Dec 2010 page 25" href="http://viewer.zmags.com/publication/e9f19faa?page=25">SOLID DOSAGEdrugs are being patented, generic </a> SOLID DOSAGEdrugs are being patented, generic <a title="Pharma Nov/Dec 2010 page 26" href="http://viewer.zmags.com/publication/e9f19faa?page=26">STRAP</a> STRAP<a title="Pharma Nov/Dec 2010 page 27" href="http://viewer.zmags.com/publication/e9f19faa?page=27">SOLID DOSAGEIn-LIne MonITorIng In soLIddose M</a> SOLID DOSAGEIn-LIne MonITorIng In soLIddose M<a title="Pharma Nov/Dec 2010 page 28" href="http://viewer.zmags.com/publication/e9f19faa?page=28">STRAPNEWWFI and buffered solutions in bagsha</a> STRAPNEWWFI and buffered solutions in bagsha<a title="Pharma Nov/Dec 2010 page 29" href="http://viewer.zmags.com/publication/e9f19faa?page=29">SOLID DOSAGEFigure 2: The TPI in-line sensor</a> SOLID DOSAGEFigure 2: The TPI in-line sensor<a title="Pharma Nov/Dec 2010 page 30" href="http://viewer.zmags.com/publication/e9f19faa?page=30">SOLID DOSAGEFigure 3</a> SOLID DOSAGEFigure 3<a title="Pharma Nov/Dec 2010 page 31" href="http://viewer.zmags.com/publication/e9f19faa?page=31">SOLID DOSAGEFigure 5: Coating thicknessdistr</a> SOLID DOSAGEFigure 5: Coating thicknessdistr<a title="Pharma Nov/Dec 2010 page 32" href="http://viewer.zmags.com/publication/e9f19faa?page=32">STRAP</a> STRAP<a title="Pharma Nov/Dec 2010 page 33" href="http://viewer.zmags.com/publication/e9f19faa?page=33">GxPsgeTTIng TherIghT BaLanCeThe healthcare in</a> GxPsgeTTIng TherIghT BaLanCeThe healthcare in<a title="Pharma Nov/Dec 2010 page 34" href="http://viewer.zmags.com/publication/e9f19faa?page=34">GxPsPhilosophies What drives</a> GxPsPhilosophies What drives<a title="Pharma Nov/Dec 2010 page 35" href="http://viewer.zmags.com/publication/e9f19faa?page=35">DRUG DISCOVERYVIsuaL anaLYsesguIde CrITICaLd</a> DRUG DISCOVERYVIsuaL anaLYsesguIde CrITICaLd<a title="Pharma Nov/Dec 2010 page 36" href="http://viewer.zmags.com/publication/e9f19faa?page=36">DRUG DISCOVERYA RESEARChER’SABILITy TO MAKEgO</a> DRUG DISCOVERYA RESEARChER’SABILITy TO MAKEgO<a title="Pharma Nov/Dec 2010 page 37" href="http://viewer.zmags.com/publication/e9f19faa?page=37">STRAPCreativeand reliable ?DC formulation</a> STRAPCreativeand reliable ?DC formulation<a title="Pharma Nov/Dec 2010 page 38" href="http://viewer.zmags.com/publication/e9f19faa?page=38">STRAPYes – with RoquetteOur directly-compre</a> STRAPYes – with RoquetteOur directly-compre<a title="Pharma Nov/Dec 2010 page 39" href="http://viewer.zmags.com/publication/e9f19faa?page=39">MANUFACTURINGFIre deTeCTIon For ThePharMaCeuT</a> MANUFACTURINGFIre deTeCTIon For ThePharMaCeuT<a title="Pharma Nov/Dec 2010 page 40" href="http://viewer.zmags.com/publication/e9f19faa?page=40">MANUFACTURINGhave </a> MANUFACTURINGhave <a title="Pharma Nov/Dec 2010 page 41" href="http://viewer.zmags.com/publication/e9f19faa?page=41">MANUFACTURINGflames. In many clean rooms, howe</a> MANUFACTURINGflames. In many clean rooms, howe<a title="Pharma Nov/Dec 2010 page 42" href="http://viewer.zmags.com/publication/e9f19faa?page=42">STRAP World-Class Tablet Coatingin a Bench Top </a> STRAP World-Class Tablet Coatingin a Bench Top <a title="Pharma Nov/Dec 2010 page 43" href="http://viewer.zmags.com/publication/e9f19faa?page=43">MANUFACTURINGTable I: Mechanical calibrationp</a> MANUFACTURINGTable I: Mechanical calibrationp<a title="Pharma Nov/Dec 2010 page 44" href="http://viewer.zmags.com/publication/e9f19faa?page=44">MANUFACTURINGFigure 1: A modern-daydissoluti</a> MANUFACTURINGFigure 1: A modern-daydissoluti<a title="Pharma Nov/Dec 2010 page 45" href="http://viewer.zmags.com/publication/e9f19faa?page=45">MANUFACTURINGFigure 2: USP Apparatus 1 (theb</a> MANUFACTURINGFigure 2: USP Apparatus 1 (theb<a title="Pharma Nov/Dec 2010 page 46" href="http://viewer.zmags.com/publication/e9f19faa?page=46">STRAPKey Insights and Successful Strategies i</a> STRAPKey Insights and Successful Strategies i<a title="Pharma Nov/Dec 2010 page 47" href="http://viewer.zmags.com/publication/e9f19faa?page=47">MANUFACTURINGFigure 3a: The vacuum formedEMC</a> MANUFACTURINGFigure 3a: The vacuum formedEMC<a title="Pharma Nov/Dec 2010 page 48" href="http://viewer.zmags.com/publication/e9f19faa?page=48">STRAPQualified Solutions for T</a> STRAPQualified Solutions for T<a title="Pharma Nov/Dec 2010 page 49" href="http://viewer.zmags.com/publication/e9f19faa?page=49">MANAGEMENTreLeVanCe and dePLoYMenToF Lean Man</a> MANAGEMENTreLeVanCe and dePLoYMenToF Lean Man<a title="Pharma Nov/Dec 2010 page 50" href="http://viewer.zmags.com/publication/e9f19faa?page=50">MANAGEMENTThe research sample included intervi</a> MANAGEMENTThe research sample included intervi<a title="Pharma Nov/Dec 2010 page 51" href="http://viewer.zmags.com/publication/e9f19faa?page=51">MANAGEMENTFigure 3: Strategy of OPEXimpleme</a> MANAGEMENTFigure 3: Strategy of OPEXimpleme<a title="Pharma Nov/Dec 2010 page 52" href="http://viewer.zmags.com/publication/e9f19faa?page=52">MANAGEMENT Today, laggards are struggling </a> MANAGEMENT Today, laggards are struggling <a title="Pharma Nov/Dec 2010 page 53" href="http://viewer.zmags.com/publication/e9f19faa?page=53">MANAGEMENTFigure 4: OPEX landscape andtrans</a> MANAGEMENTFigure 4: OPEX landscape andtrans<a title="Pharma Nov/Dec 2010 page 54" href="http://viewer.zmags.com/publication/e9f19faa?page=54">STRAP Look to A</a> STRAP Look to A<a title="Pharma Nov/Dec 2010 page 55" href="http://viewer.zmags.com/publication/e9f19faa?page=55">DOCUMENT EXCHANGELIFesCIenCesJoIns TheCLoud</a> DOCUMENT EXCHANGELIFesCIenCesJoIns TheCLoud<a title="Pharma Nov/Dec 2010 page 56" href="http://viewer.zmags.com/publication/e9f19faa?page=56">STRAPHave You Got What It Takes To Be Th</a> STRAPHave You Got What It Takes To Be Th<a title="Pharma Nov/Dec 2010 page 57" href="http://viewer.zmags.com/publication/e9f19faa?page=57">DOCUMENT EXCHANGEFigure 1: Critical security</a> DOCUMENT EXCHANGEFigure 1: Critical security<a title="Pharma Nov/Dec 2010 page 58" href="http://viewer.zmags.com/publication/e9f19faa?page=58">German Engineeringwith ExperienceYour Ben</a> German Engineeringwith ExperienceYour Ben<a title="Pharma Nov/Dec 2010 page 59" href="http://viewer.zmags.com/publication/e9f19faa?page=59">DOCUMENT EXCHANGEAlison </a> DOCUMENT EXCHANGEAlison <a title="Pharma Nov/Dec 2010 page 60" href="http://viewer.zmags.com/publication/e9f19faa?page=60">PLEASE MARK YOUR CALENDARS AND PLAN TO ATTEND!</a> PLEASE MARK YOUR CALENDARS AND PLAN TO ATTEND!<a title="Pharma Nov/Dec 2010 page 61" href="http://viewer.zmags.com/publication/e9f19faa?page=61">DRUG DEVELOPMENTIn drug deVeLoPMenT,noT aLL P</a> DRUG DEVELOPMENTIn drug deVeLoPMenT,noT aLL P<a title="Pharma Nov/Dec 2010 page 62" href="http://viewer.zmags.com/publication/e9f19faa?page=62">DRUG DEVELOPMENThave a greater chance of attra</a> DRUG DEVELOPMENThave a greater chance of attra<a title="Pharma Nov/Dec 2010 page 63" href="http://viewer.zmags.com/publication/e9f19faa?page=63">DRUG DEVELOPMENTBest Practicein ActionImperia</a> DRUG DEVELOPMENTBest Practicein ActionImperia<a title="Pharma Nov/Dec 2010 page 64" href="http://viewer.zmags.com/publication/e9f19faa?page=64">SHARED VALUES – SHARED SUCCESSBrenntag Pharm</a> SHARED VALUES – SHARED SUCCESSBrenntag Pharm<a title="Pharma Nov/Dec 2010 page 65" href="http://viewer.zmags.com/publication/e9f19faa?page=65">SUPPLY CHAINdrIVIng Change In TheIndIan PharM</a> SUPPLY CHAINdrIVIng Change In TheIndIan PharM<a title="Pharma Nov/Dec 2010 page 66" href="http://viewer.zmags.com/publication/e9f19faa?page=66">STRAPinnovationthat doesn't cost</a> STRAPinnovationthat doesn't cost<a title="Pharma Nov/Dec 2010 page 67" href="http://viewer.zmags.com/publication/e9f19faa?page=67">R&DMarcel Jaspars collectingspecimens in th</a> R&DMarcel Jaspars collectingspecimens in th<a title="Pharma Nov/Dec 2010 page 68" href="http://viewer.zmags.com/publication/e9f19faa?page=68">November/December 2010 </a> November/December 2010 <a title="Pharma Nov/Dec 2010 page 69" href="http://viewer.zmags.com/publication/e9f19faa?page=69">PATENTSsTruCTuraLLY sIMILar,BuT eFFeCTIVeLY d</a> PATENTSsTruCTuraLLY sIMILar,BuT eFFeCTIVeLY d<a title="Pharma Nov/Dec 2010 page 70" href="http://viewer.zmags.com/publication/e9f19faa?page=70">PATENTSskilled person the “uninventive man</a> PATENTSskilled person the “uninventive man<a title="Pharma Nov/Dec 2010 page 71" href="http://viewer.zmags.com/publication/e9f19faa?page=71">PATENTS known process, machine or</a> PATENTS known process, machine or<a title="Pharma Nov/Dec 2010 page 72" href="http://viewer.zmags.com/publication/e9f19faa?page=72">10th Annual24th - 26th January | The</a> 10th Annual24th - 26th January | The<a title="Pharma Nov/Dec 2010 page 73" href="http://viewer.zmags.com/publication/e9f19faa?page=73">SHOWCASETo advertise here call +44 (0) 1372 364 </a> SHOWCASETo advertise here call +44 (0) 1372 364 <a title="Pharma Nov/Dec 2010 page 74" href="http://viewer.zmags.com/publication/e9f19faa?page=74">SHOWCASETo advertise here call +44 (0) 1372 364 </a> SHOWCASETo advertise here call +44 (0) 1372 364 <a title="Pharma Nov/Dec 2010 page 75" href="http://viewer.zmags.com/publication/e9f19faa?page=75">NOSTRAPHARMUSPersonaLIZed MedICInesThe TreaTM</a> NOSTRAPHARMUSPersonaLIZed MedICInesThe TreaTM<a title="Pharma Nov/Dec 2010 page 76" href="http://viewer.zmags.com/publication/e9f19faa?page=76">InnovativeFiltration.The ZetaPlusEncapsula.</a> InnovativeFiltration.The ZetaPlusEncapsula.<a title="Pharma Nov/Dec 2010 page 77" href="http://viewer.zmags.com/publication/e9f19faa?page=77">STRAPSINGLE-USE TECHNOLOGYNew BIOSTAT® Cu</a> STRAPSINGLE-USE TECHNOLOGYNew BIOSTAT® Cu<a title="Pharma Nov/Dec 2010 page 78" href="http://viewer.zmags.com/publication/e9f19faa?page=78">STRAPCopyright © 2010 Quintilesbelieves adher</a> STRAPCopyright © 2010 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