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RESPIRATORY
ISSN 2054-3166 Vol 3.1 • May 2015 • emjreviews.com
CONTENTS
EDITORIAL BOARD................................................................................................................................. 4
EDITOR’S PICK: THE ELECTRONIC NOSE ARISES INTO THE 21ST CENTURY................................... 12
• Federico Fiorentino et al.
TREATMENT OF ISOLATED INTRACRANIAL PROGRESSION OF LUNG CANCER DURING
TREATMENT WITH SYSTEMIC EPIDERMAL GROWTH FACTOR RECEPTOR TYROSINE
KINASE INHIBITORS (EGFR-TKIs)………………………..................................................................................... 19
• Amanda Tufman et al.
FREQUENT EXACERBATORS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE: FROM
RESEARCH TO CLINICAL PRACTICE ....................................................................................................
RESPIRATORY ISSN 2054-3166
CONTENTS EDITORIAL BOARD.......................
RESPIRATORY NERVES, COUGH, AND IDIOPATHIC PULMO
Editorial Board Editor-in-Chief: Prof Nikolaos
Respiratory Disease, Helmholtz Zentrum Münch
European Medical Journal EMJ Respiratory Vol 3.
Welcome Hello and a warm welcome to the latest
18th ECCO - 40th ESMO E
Foreword
Available Now! The additional EMJ eJournals i
Editor’s Pick: State of the Art of Aortic Valve I
EDITOR’S PICK An e
important information. For example, ‘smellprints’
Breathprints from AECOPD patients wer
sleep apnoea syndrome (OSAS) has also been
The sensitivity and specificity were 100% an
studies including population-based screening for
SUBSCRIBE FREE TO OUR YOUTUBE CHANNEL www.youtube
TREATMENT OF ISOLATED INTRACRANIAL P
BACKGROUND Advanced-stage lung cancer carries a
tomography showed metastases in the liv
A PFS or OS advantage for concurrent erlotinib du
progressing under standard doses of EGFR-TKI
Table 1 continued. Publication n EGFR mut
did not include patients treated concurrentl
Figure 2: MRI image (T2W) showing hygroma develop
clinical trials. If clinical trials are not avail
for multiple brain metastases from non- small-cel
FREQUENT EXACERBATORS IN CHRONIC OBSTRUCTIVE
previous year and daily respiratory symptoms were
biomarker or combination of biomarkers, and
20% of patients with FEV >50% predicted and
exacerbations, compared with 40.8% of those takin
phenotype alone. The beneficial clinical effects o
REFERENCES 1. Halbert RJ et al. Global burden of
Int J Chron Obstruct Pulmon Dis. 2014;9
Would you like to write for the EMJ blog? Intera
NERVES, COUGH, AND IDIOPATHIC PULMONAR
The latter, which can be demonstrated using
by Leslie.20 It is known that these forces
COMORBIDITIES Gastro-Oesophageal Reflux Disease Th
It has been proposed that these neurotrophi
TREATMENT OF COUGH Treatment of IPF-associat
REFERENCES 1. Gribbin J et al. Incidence and mor
43. Jung HK et al. Gastroesophageal reflux disease
ESTABLISHED STATIN USE REDUCES MORTALITY FROM
Statins are already a widely used group of drugs,
Inclusion Criteria i) Studies in which ST was e
considered in the adjusted analysis (age, s
Table 1 Continued. Study Population studied D
Established ST and Development of CAP Eight studi
Figure 1C: Effect of established statin therapy o
pooled analysis shows that this is not significant
to recruit to RCTs, many have terminated early an
28. Majumdar SR et al. Statins and outcomes
EUROPEAN MEDICAL JOURNAL provides influential arti
DEEP NECK ABSCESSES COMPLICATING ACUTE
within normal ranges. The monosticon test for the
LS and Epstein–Barr virus (EBV) infecti
ADVANCES IN THE DIAGNOSIS OF HIV-ASSOCIATED TUBER
Addressing the scale of the TB epidemic an
Early development Late development Due to be eval
compared with sputum-smear microscopy, and re
Loop-Mediated Isothermal Amplification The loop-me
Some variation in specificity of urine-LAM assays
Comparative diagnostic yield (%) 100 90 80 70 60
burden settings have demonstrated that Xpert has
6. Elliott AM et al. The impact of human immunode
for extrapulmonary and pulmonary tuberculos
87. Lawn SD et al. HIV-associated tuber
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