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<br /> EUROPEAN MEDICAL JOURNAL<br /> ISSN 2397-6764 Vol 2.2 • June 2017 • europeanmedical-journal.com<br /> CONTENTS<br /> EDITORIAL BOARD...................................................................................................................................... 4<br /> FEATURE<br /> • ‘VAGINAL REJUVENATION’ AND THE REGULATION OF NEW TECHNOLOGIES:<br /> CONTROLS ARE STILL LACKING........................................................................................................ 12<br /> Antonios Antoniou, Ahmed Yassin<br /> ARTICLES<br /> • EDITOR’S PICK: A REGENERATIVE BIOLOGY VIEW ON ARTIFICIAL TISSUE<br /> CONSTRUCTION AND THREE-DIMENSIONAL BIOPRINTING: WHAT MAY WE LEARN<br /> FROM NATURAL REGENERATIVE PHENOMENA?.......................................................................... 16<br /> Henrik Lauridsen<br /> • EFFICACY OF THE ARTIFICIAL URINARY SPHINCTER ZSI 375 FOR TREATME<a title="EMJ 2.2 2017 page 1" href="http://viewer.zmags.com/publication/39024323?page=1"> EUROPEAN MEDICAL JOURNAL ISSN 2397-6764 </a> <a title="EMJ 2.2 2017 page 2" href="http://viewer.zmags.com/publication/39024323?page=2"> CONTENTS EDITORIAL BOARD.......................</a> <a title="EMJ 2.2 2017 page 3" href="http://viewer.zmags.com/publication/39024323?page=3"> EUROPEAN MEDICAL JOURNAL • EPITHELIAL-MESENCHYM</a> <a title="EMJ 2.2 2017 page 4" href="http://viewer.zmags.com/publication/39024323?page=4"> EDITORIAL BOARD EDITOR-IN-CHIEF Prof Markus Pec</a> <a title="EMJ 2.2 2017 page 5" href="http://viewer.zmags.com/publication/39024323?page=5"> EUROPEAN MEDICAL JOURNAL AIMS AND SCOPE • T</a> <a title="EMJ 2.2 2017 page 6" href="http://viewer.zmags.com/publication/39024323?page=6"> EUROPEAN MEDICAL JOURNAL 2.2 JUNE 2017 Director </a> <a title="EMJ 2.2 2017 page 7" href="http://viewer.zmags.com/publication/39024323?page=7"> Welcome Hello and welcome to the second editio</a> <a title="EMJ 2.2 2017 page 8" href="http://viewer.zmags.com/publication/39024323?page=8"> Bosulif® (bosutinib): Helping you give the ri</a> <a title="EMJ 2.2 2017 page 9" href="http://viewer.zmags.com/publication/39024323?page=9"> Foreword </a> <a title="EMJ 2.2 2017 page 10" href="http://viewer.zmags.com/publication/39024323?page=10"> EMJ Innovations 1.1 2017 Includes a s</a> <a title="EMJ 2.2 2017 page 11" href="http://viewer.zmags.com/publication/39024323?page=11"> Review of the European Association of Urology Con</a> <a title="EMJ 2.2 2017 page 12" href="http://viewer.zmags.com/publication/39024323?page=12"> ‘VAGINAL REJUVENATION’ AND THE REGULATION OF NEW </a> <a title="EMJ 2.2 2017 page 13" href="http://viewer.zmags.com/publication/39024323?page=13"> base of evidence prior to using such products on </a> <a title="EMJ 2.2 2017 page 14" href="http://viewer.zmags.com/publication/39024323?page=14"> REFERENCES 1. Karcher C, Sadick N. Vag</a> <a title="EMJ 2.2 2017 page 15" href="http://viewer.zmags.com/publication/39024323?page=15"> Watch our exclusive interviews from a variety of </a> <a title="EMJ 2.2 2017 page 16" href="http://viewer.zmags.com/publication/39024323?page=16"> EDITOR’S PICK The choice of editor’s</a> <a title="EMJ 2.2 2017 page 17" href="http://viewer.zmags.com/publication/39024323?page=17"> a bit between different organisms. Humans and mam</a> <a title="EMJ 2.2 2017 page 18" href="http://viewer.zmags.com/publication/39024323?page=18"> in the lab. One way to circumvent this limitation</a> <a title="EMJ 2.2 2017 page 19" href="http://viewer.zmags.com/publication/39024323?page=19"> 3D printing technologies into seven categori</a> <a title="EMJ 2.2 2017 page 20" href="http://viewer.zmags.com/publication/39024323?page=20"> 3D bioprinting technology eventually matures to t</a> <a title="EMJ 2.2 2017 page 21" href="http://viewer.zmags.com/publication/39024323?page=21"> REFERENCES 1. Goss RJ, Principles of regene</a> <a title="EMJ 2.2 2017 page 22" href="http://viewer.zmags.com/publication/39024323?page=22"> EFFICACY OF THE ARTIFICIAL URINARY SPHINCTER </a> <a title="EMJ 2.2 2017 page 23" href="http://viewer.zmags.com/publication/39024323?page=23"> Introduction of the antibiotic coating InhibiZone</a> <a title="EMJ 2.2 2017 page 24" href="http://viewer.zmags.com/publication/39024323?page=24"> The aetiologies of incontinence were ra</a> <a title="EMJ 2.2 2017 page 25" href="http://viewer.zmags.com/publication/39024323?page=25"> Table 2: ZSI 375 complications. Complications </a> <a title="EMJ 2.2 2017 page 26" href="http://viewer.zmags.com/publication/39024323?page=26"> 13.James MH, McCammon KA. Artificial urinary sphin</a> <a title="EMJ 2.2 2017 page 27" href="http://viewer.zmags.com/publication/39024323?page=27"> EUROPEAN MEDICAL JOURNAL provides influential arti</a> <a title="EMJ 2.2 2017 page 28" href="http://viewer.zmags.com/publication/39024323?page=28"> DIGITAL TECHNOLOGY HEALTHCARE SOLUTIONS IN AN ER</a> <a title="EMJ 2.2 2017 page 29" href="http://viewer.zmags.com/publication/39024323?page=29"> tools that hold promise for increasing healthcare</a> <a title="EMJ 2.2 2017 page 30" href="http://viewer.zmags.com/publication/39024323?page=30"> reduce access to food labels, which are important</a> <a title="EMJ 2.2 2017 page 31" href="http://viewer.zmags.com/publication/39024323?page=31"> THE ROLE AND SUCCESS OF MOBILE DIGITAL INTERVENTI</a> <a title="EMJ 2.2 2017 page 32" href="http://viewer.zmags.com/publication/39024323?page=32"> most vulnerable across societies, this could bree</a> <a title="EMJ 2.2 2017 page 33" href="http://viewer.zmags.com/publication/39024323?page=33"> LIMITATIONS Few studies have considered the prev</a> <a title="EMJ 2.2 2017 page 34" href="http://viewer.zmags.com/publication/39024323?page=34"> in high-income countries: risk and protec</a> <a title="EMJ 2.2 2017 page 35" href="http://viewer.zmags.com/publication/39024323?page=35"> COMPREHENSIVE ASSESSMENT AND PHARMA</a> <a title="EMJ 2.2 2017 page 36" href="http://viewer.zmags.com/publication/39024323?page=36"> a lesion or disease affecting the somatosensory s</a> <a title="EMJ 2.2 2017 page 37" href="http://viewer.zmags.com/publication/39024323?page=37"> Some other validated, multi-dimensional p</a> <a title="EMJ 2.2 2017 page 38" href="http://viewer.zmags.com/publication/39024323?page=38"> - Dysaesthesia: burning/stabbing - Paraesthes</a> <a title="EMJ 2.2 2017 page 39" href="http://viewer.zmags.com/publication/39024323?page=39"> them to be more motivated and adherent to the tre</a> <a title="EMJ 2.2 2017 page 40" href="http://viewer.zmags.com/publication/39024323?page=40"> treatment with antiviral medications can reduce t</a> <a title="EMJ 2.2 2017 page 41" href="http://viewer.zmags.com/publication/39024323?page=41"> 12. American Pain Society. Pain: Current Understa</a> <a title="EMJ 2.2 2017 page 42" href="http://viewer.zmags.com/publication/39024323?page=42"> BENCHMARKING OUTCOMES THAT MATTER MOST TO</a> <a title="EMJ 2.2 2017 page 43" href="http://viewer.zmags.com/publication/39024323?page=43"> achieved per dollar expended.3,4 Outcomes ar</a> <a title="EMJ 2.2 2017 page 44" href="http://viewer.zmags.com/publication/39024323?page=44"> The GLOBE pilot programme will bring together hig</a> <a title="EMJ 2.2 2017 page 45" href="http://viewer.zmags.com/publication/39024323?page=45"> HKO, and CAT Standard Sets, and from the ICHOM gl</a> <a title="EMJ 2.2 2017 page 46" href="http://viewer.zmags.com/publication/39024323?page=46"> Connecticut Joint Replacement Institute (CJRI), C</a> <a title="EMJ 2.2 2017 page 47" href="http://viewer.zmags.com/publication/39024323?page=47"> Standard Sets. Sites were vetted to ensure t</a> <a title="EMJ 2.2 2017 page 48" href="http://viewer.zmags.com/publication/39024323?page=48"> Jul Aug Sep Oct Nov Dec</a> <a title="EMJ 2.2 2017 page 49" href="http://viewer.zmags.com/publication/39024323?page=49"> 2007;356:316-7. 4. Porter ME, Teisberg EO. Redefin</a> <a title="EMJ 2.2 2017 page 50" href="http://viewer.zmags.com/publication/39024323?page=50"> EPITHELIAL-MESENCHYMAL TRANSITION IN DOCETAXEL-RE</a> <a title="EMJ 2.2 2017 page 51" href="http://viewer.zmags.com/publication/39024323?page=51"> EPITHELIAL-MESENCHYMAL TRANSITION EMT is a proce</a> <a title="EMJ 2.2 2017 page 52" href="http://viewer.zmags.com/publication/39024323?page=52"> enhanced mice sensitivity to the chemotherap</a> <a title="EMJ 2.2 2017 page 53" href="http://viewer.zmags.com/publication/39024323?page=53"> castration-resistant LAPC9 xenografts and als</a> <a title="EMJ 2.2 2017 page 54" href="http://viewer.zmags.com/publication/39024323?page=54"> The expression of EMT genes also correlated</a> <a title="EMJ 2.2 2017 page 55" href="http://viewer.zmags.com/publication/39024323?page=55"> cancers, including CRPCa. However, the clini</a> <a title="EMJ 2.2 2017 page 56" href="http://viewer.zmags.com/publication/39024323?page=56"> androgen-deprivation therapy. Cancer Res. 201</a> <a title="EMJ 2.2 2017 page 57" href="http://viewer.zmags.com/publication/39024323?page=57"> CONCERNS ABOUT THE USE OF NON-HIGH-DENSITY LIPOPR</a> <a title="EMJ 2.2 2017 page 58" href="http://viewer.zmags.com/publication/39024323?page=58"> While the concept of non-HDL cholesterol is not n</a> <a title="EMJ 2.2 2017 page 59" href="http://viewer.zmags.com/publication/39024323?page=59"> mid-sternal chest pain (described as a pressure, </a> <a title="EMJ 2.2 2017 page 60" href="http://viewer.zmags.com/publication/39024323?page=60"> of ATD onset is determined by the associated CRF </a> <a title="EMJ 2.2 2017 page 61" href="http://viewer.zmags.com/publication/39024323?page=61"> Table 3: Cholesterol retention fraction versus no</a> <a title="EMJ 2.2 2017 page 62" href="http://viewer.zmags.com/publication/39024323?page=62"> below 0.59 (precipitation method but 0.49 using t</a> <a title="EMJ 2.2 2017 page 63" href="http://viewer.zmags.com/publication/39024323?page=63"> non-HDL cholesterol does not necessarily portend </a> <a title="EMJ 2.2 2017 page 64" href="http://viewer.zmags.com/publication/39024323?page=64"> 19. Blaha MJ et al. The importance of non-HDL ch</a> <a title="EMJ 2.2 2017 page 65" href="http://viewer.zmags.com/publication/39024323?page=65"> OCCUPATIONAL ALLERGY *Stacey E. Anderson,1 Carrie</a> <a title="EMJ 2.2 2017 page 66" href="http://viewer.zmags.com/publication/39024323?page=66"> Table 1: Common occupational allergens. Agent </a> <a title="EMJ 2.2 2017 page 67" href="http://viewer.zmags.com/publication/39024323?page=67"> cytokines to attract and activate macrophages at </a> <a title="EMJ 2.2 2017 page 68" href="http://viewer.zmags.com/publication/39024323?page=68"> exist in the diagnosis and identification of HMW a</a> <a title="EMJ 2.2 2017 page 69" href="http://viewer.zmags.com/publication/39024323?page=69"> nickel, palladium, and mercury are known to induc</a> <a title="EMJ 2.2 2017 page 70" href="http://viewer.zmags.com/publication/39024323?page=70"> However, numerous approaches that integrate risk </a> <a title="EMJ 2.2 2017 page 71" href="http://viewer.zmags.com/publication/39024323?page=71"> allergic contact dermatitis. Allergy. 2011; 66(9)</a> <a title="EMJ 2.2 2017 page 72" href="http://viewer.zmags.com/publication/39024323?page=72"> EXTENSION OF 2016 WORLD HEALTH </a> <a title="EMJ 2.2 2017 page 73" href="http://viewer.zmags.com/publication/39024323?page=73"> Dameshek2 One cause hypothesis of PV as a trilin</a> <a title="EMJ 2.2 2017 page 74" href="http://viewer.zmags.com/publication/39024323?page=74"> (haemoglobin [Hb] >18 g/dL, Ht >0.52 in males and</a> <a title="EMJ 2.2 2017 page 75" href="http://viewer.zmags.com/publication/39024323?page=75"> Vainchenker and Constantinescu9 proposed the </a> <a title="EMJ 2.2 2017 page 76" href="http://viewer.zmags.com/publication/39024323?page=76"> Table 1: International Clinical, Laboratory, </a> <a title="EMJ 2.2 2017 page 77" href="http://viewer.zmags.com/publication/39024323?page=77"> Table 2: International Clinical Molecular and Pat</a> <a title="EMJ 2.2 2017 page 78" href="http://viewer.zmags.com/publication/39024323?page=78"> patients, the overall survival (OS) at 10 years w</a> <a title="EMJ 2.2 2017 page 79" href="http://viewer.zmags.com/publication/39024323?page=79"> mutated MPN remained <50%, which is completely in</a> <a title="EMJ 2.2 2017 page 80" href="http://viewer.zmags.com/publication/39024323?page=80"> Constantinescu, Kralovics, and Vainchenk</a> <a title="EMJ 2.2 2017 page 81" href="http://viewer.zmags.com/publication/39024323?page=81"> criteria for the diagnosis, classification and st</a> <a title="EMJ 2.2 2017 page 82" href="http://viewer.zmags.com/publication/39024323?page=82"> THE ‘NUCLEOLUS’ HYPOTHESIS OF AUTOIMMUNE </a> <a title="EMJ 2.2 2017 page 83" href="http://viewer.zmags.com/publication/39024323?page=83"> Table 1: Arguments supporting the nucleolus hypot</a> <a title="EMJ 2.2 2017 page 84" href="http://viewer.zmags.com/publication/39024323?page=84"> repair and methylation, scaffold attachment, and </a> <a title="EMJ 2.2 2017 page 85" href="http://viewer.zmags.com/publication/39024323?page=85"> methylation, which is important in epigenetic con</a> <a title="EMJ 2.2 2017 page 86" href="http://viewer.zmags.com/publication/39024323?page=86"> A B Spermine in Z-DNA NAP in </a> <a title="EMJ 2.2 2017 page 87" href="http://viewer.zmags.com/publication/39024323?page=87"> (PAD4), a calcium-activated enzyme that converts </a> <a title="EMJ 2.2 2017 page 88" href="http://viewer.zmags.com/publication/39024323?page=88"> When released, negative supercoiling stre</a> <a title="EMJ 2.2 2017 page 89" href="http://viewer.zmags.com/publication/39024323?page=89"> 20. Froberg JE et al. Guided by RNAs: X-inactivat</a> <a title="EMJ 2.2 2017 page 90" href="http://viewer.zmags.com/publication/39024323?page=90"> PAIN DURING ILLUSORY OWN ARM MOVEMENT: A STU</a> <a title="EMJ 2.2 2017 page 91" href="http://viewer.zmags.com/publication/39024323?page=91"> neuropathic pain in patients with incomplete spin</a> <a title="EMJ 2.2 2017 page 92" href="http://viewer.zmags.com/publication/39024323?page=92"> California, USA). Noise isolation was ensured by </a> <a title="EMJ 2.2 2017 page 93" href="http://viewer.zmags.com/publication/39024323?page=93"> questionnaires, participants were told that there</a> <a title="EMJ 2.2 2017 page 94" href="http://viewer.zmags.com/publication/39024323?page=94"> Mean and standard errors of the pain thresholds r</a> <a title="EMJ 2.2 2017 page 95" href="http://viewer.zmags.com/publication/39024323?page=95"> Resulting data from all conditions were normally </a> <a title="EMJ 2.2 2017 page 96" href="http://viewer.zmags.com/publication/39024323?page=96"> combination of the vision of the body and limb mo</a> <a title="EMJ 2.2 2017 page 97" href="http://viewer.zmags.com/publication/39024323?page=97"> 5. Chan BL et al. Mirror therapy for phant</a> <a title="EMJ 2.2 2017 page 98" href="http://viewer.zmags.com/publication/39024323?page=98"> PARADIGM SHIFT FOR THROMBOLYSIS IN </a> <a title="EMJ 2.2 2017 page 99" href="http://viewer.zmags.com/publication/39024323?page=99"> as medical cost, limited availability of mo</a> <a title="EMJ 2.2 2017 page 100" href="http://viewer.zmags.com/publication/39024323?page=100"> to understand how quickly IAT is initiated, OTR i</a> <a title="EMJ 2.2 2017 page 101" href="http://viewer.zmags.com/publication/39024323?page=101"> ischaemic lesion is related with a hi</a> <a title="EMJ 2.2 2017 page 102" href="http://viewer.zmags.com/publication/39024323?page=102"> REFERENCES 1. Tissue plasminogen activator for a</a> <a title="EMJ 2.2 2017 page 103" href="http://viewer.zmags.com/publication/39024323?page=103"> as assessed by pre- and post-thrombolytic angiogr</a> <a title="EMJ 2.2 2017 page 104" href="http://viewer.zmags.com/publication/39024323?page=104"> SUBSCRIBE TO RECEIVE THE LATEST PUBLICATIONS, NEW</a>