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<br /> HEPATOLOGY<br /> ISSN 2053-4221 Vol 6.1 • May 2018 • europeanmedical-journal.com<br /> INSIDE<br /> Review of<br /> ILC 2018<br /> Paris, France<br /> Contents<br /> EDITORIAL BOARD 4<br /> WELCOME 7<br /> FOREWORD 9<br /> 01 CONGRESS REVIEW<br /> Review of the ILC 2018, held in Paris, France, 11th–15th April 2018 12<br /> 02 INTERVIEWS WITH EMJ HEPATOLOGY EDITORIAL BOARD<br /> Dr Amedeo Lonardo 30<br /> Dr Diego Calvisi <a title="EMJ Hepatology 6.1 2018 page 1" href="http://viewer.zmags.com/publication/d158c33c?page=1"> HEPATOLOGY ISSN 2053-4221 </a> <a title="EMJ Hepatology 6.1 2018 page 2" href="http://viewer.zmags.com/publication/d158c33c?page=2"> Contents EDITORIAL BOARD </a> <a title="EMJ Hepatology 6.1 2018 page 3" href="http://viewer.zmags.com/publication/d158c33c?page=3"> “We hope that the variety held within its p</a> <a title="EMJ Hepatology 6.1 2018 page 4" href="http://viewer.zmags.com/publication/d158c33c?page=4"> Editorial Board Editor-in-Chief Prof Markus Peck-</a> <a title="EMJ Hepatology 6.1 2018 page 5" href="http://viewer.zmags.com/publication/d158c33c?page=5"> Aims and Scope The European Medical Journal (EMJ)</a> <a title="EMJ Hepatology 6.1 2018 page 6" href="http://viewer.zmags.com/publication/d158c33c?page=6"> Masthead Chief Executive Officer Spencer Gore Sen</a> <a title="EMJ Hepatology 6.1 2018 page 7" href="http://viewer.zmags.com/publication/d158c33c?page=7"> Welcome I take great pleasure and pride in welcom</a> <a title="EMJ Hepatology 6.1 2018 page 8" href="http://viewer.zmags.com/publication/d158c33c?page=8"> Want a daily dose of healthcare straight to </a> <a title="EMJ Hepatology 6.1 2018 page 9" href="http://viewer.zmags.com/publication/d158c33c?page=9"> Foreword Dear colleagues, I would like to welcome</a> <a title="EMJ Hepatology 6.1 2018 page 10" href="http://viewer.zmags.com/publication/d158c33c?page=10"> Available now.</a> <a title="EMJ Hepatology 6.1 2018 page 11" href="http://viewer.zmags.com/publication/d158c33c?page=11"> Featured inside: Congress Review + Review of M</a> <a title="EMJ Hepatology 6.1 2018 page 12" href="http://viewer.zmags.com/publication/d158c33c?page=12"> </a> <a title="EMJ Hepatology 6.1 2018 page 13" href="http://viewer.zmags.com/publication/d158c33c?page=13"> Congress Review Review of the Euro</a> <a title="EMJ Hepatology 6.1 2018 page 14" href="http://viewer.zmags.com/publication/d158c33c?page=14"> The meeting also included, for the first time, a c</a> <a title="EMJ Hepatology 6.1 2018 page 15" href="http://viewer.zmags.com/publication/d158c33c?page=15"> Presentation of New Liver Dialysis Technology NEW</a> <a title="EMJ Hepatology 6.1 2018 page 16" href="http://viewer.zmags.com/publication/d158c33c?page=16"> transplant patients, with no new lesions detected</a> <a title="EMJ Hepatology 6.1 2018 page 17" href="http://viewer.zmags.com/publication/d158c33c?page=17"> With structured lifestyle intervention progra</a> <a title="EMJ Hepatology 6.1 2018 page 18" href="http://viewer.zmags.com/publication/d158c33c?page=18"> Paris Expo Porte de Versailles Venue for the ILC </a> <a title="EMJ Hepatology 6.1 2018 page 19" href="http://viewer.zmags.com/publication/d158c33c?page=19"> Creative Commons Attribution-Non Commercial 4.0 </a> <a title="EMJ Hepatology 6.1 2018 page 20" href="http://viewer.zmags.com/publication/d158c33c?page=20"> "Relevant changes are on the way for the manag</a> <a title="EMJ Hepatology 6.1 2018 page 21" href="http://viewer.zmags.com/publication/d158c33c?page=21"> The researchers also reported that there were no </a> <a title="EMJ Hepatology 6.1 2018 page 22" href="http://viewer.zmags.com/publication/d158c33c?page=22"> Commenting on the encouraging results, Mr</a> <a title="EMJ Hepatology 6.1 2018 page 23" href="http://viewer.zmags.com/publication/d158c33c?page=23"> Further work needs to be carried out to establish</a> <a title="EMJ Hepatology 6.1 2018 page 24" href="http://viewer.zmags.com/publication/d158c33c?page=24"> Treatment of Rare Liver Diseases PROMISING PROGR</a> <a title="EMJ Hepatology 6.1 2018 page 25" href="http://viewer.zmags.com/publication/d158c33c?page=25"> treatment, was measured in both Italian and</a> <a title="EMJ Hepatology 6.1 2018 page 26" href="http://viewer.zmags.com/publication/d158c33c?page=26"> In the first study, PBC patients with a po</a> <a title="EMJ Hepatology 6.1 2018 page 27" href="http://viewer.zmags.com/publication/d158c33c?page=27"> The rarely fatal hepatitis A infection was shown </a> <a title="EMJ Hepatology 6.1 2018 page 28" href="http://viewer.zmags.com/publication/d158c33c?page=28"> Direct-Acting Antiviral Agent Therapy Slowing Hep</a> <a title="EMJ Hepatology 6.1 2018 page 29" href="http://viewer.zmags.com/publication/d158c33c?page=29"> Our ILC videos: </a> <a title="EMJ Hepatology 6.1 2018 page 30" href="http://viewer.zmags.com/publication/d158c33c?page=30"> Interviews A selection of insightful intervie</a> <a title="EMJ Hepatology 6.1 2018 page 31" href="http://viewer.zmags.com/publication/d158c33c?page=31"> "A call to action is necessary to prevent the </a> <a title="EMJ Hepatology 6.1 2018 page 32" href="http://viewer.zmags.com/publication/d158c33c?page=32"> Clostridium difficile. Of course, this is not to </a> <a title="EMJ Hepatology 6.1 2018 page 33" href="http://viewer.zmags.com/publication/d158c33c?page=33"> young hepatologists that, while an individual’s </a> <a title="EMJ Hepatology 6.1 2018 page 34" href="http://viewer.zmags.com/publication/d158c33c?page=34"> deleterious effects on treatments. Furthermore, i</a> <a title="EMJ Hepatology 6.1 2018 page 35" href="http://viewer.zmags.com/publication/d158c33c?page=35"> and showed no benefits on the treated </a> <a title="EMJ Hepatology 6.1 2018 page 36" href="http://viewer.zmags.com/publication/d158c33c?page=36"> nurse-led service, especially for viral hepatitis</a> <a title="EMJ Hepatology 6.1 2018 page 37" href="http://viewer.zmags.com/publication/d158c33c?page=37"> is self-induced, has meant that stigmatism h</a> <a title="EMJ Hepatology 6.1 2018 page 38" href="http://viewer.zmags.com/publication/d158c33c?page=38"> Dr Dhiraj Tripathi Queen Elizabeth Hospital Birmi</a> <a title="EMJ Hepatology 6.1 2018 page 39" href="http://viewer.zmags.com/publication/d158c33c?page=39"> Is variceal bleeding in cirrhosis patients a grow</a> <a title="EMJ Hepatology 6.1 2018 page 40" href="http://viewer.zmags.com/publication/d158c33c?page=40"> we were doing about 200. So, in the last 10 years</a> <a title="EMJ Hepatology 6.1 2018 page 41" href="http://viewer.zmags.com/publication/d158c33c?page=41"> interest and supported my research; he was </a> <a title="EMJ Hepatology 6.1 2018 page 42" href="http://viewer.zmags.com/publication/d158c33c?page=42"> Updated Symposium Review coming soon. 42 HEPATO</a> <a title="EMJ Hepatology 6.1 2018 page 43" href="http://viewer.zmags.com/publication/d158c33c?page=43"> Updated Symposium Review coming soon. Creative </a> <a title="EMJ Hepatology 6.1 2018 page 44" href="http://viewer.zmags.com/publication/d158c33c?page=44"> Updated Symposium Review coming soon. 44 HEPATO</a> <a title="EMJ Hepatology 6.1 2018 page 45" href="http://viewer.zmags.com/publication/d158c33c?page=45"> Updated Symposium Review coming soon. Creative </a> <a title="EMJ Hepatology 6.1 2018 page 46" href="http://viewer.zmags.com/publication/d158c33c?page=46"> Updated Symposium Review coming soon. 46 HEPATO</a> <a title="EMJ Hepatology 6.1 2018 page 47" href="http://viewer.zmags.com/publication/d158c33c?page=47"> Updated Symposium Review coming soon. Creative </a> <a title="EMJ Hepatology 6.1 2018 page 48" href="http://viewer.zmags.com/publication/d158c33c?page=48"> Updated Symposium Review coming soon. 48 HEPATO</a> <a title="EMJ Hepatology 6.1 2018 page 49" href="http://viewer.zmags.com/publication/d158c33c?page=49"> Updated Symposium Review coming soon. Creative </a> <a title="EMJ Hepatology 6.1 2018 page 50" href="http://viewer.zmags.com/publication/d158c33c?page=50"> Updated Symposium Review coming soon. 50 HEPATO</a> <a title="EMJ Hepatology 6.1 2018 page 51" href="http://viewer.zmags.com/publication/d158c33c?page=51"> Updated Symposium Review coming soon. Creative </a> <a title="EMJ Hepatology 6.1 2018 page 52" href="http://viewer.zmags.com/publication/d158c33c?page=52"> Updated Symposium Review coming soon. 52 HEPATO</a> <a title="EMJ Hepatology 6.1 2018 page 53" href="http://viewer.zmags.com/publication/d158c33c?page=53"> Updated Symposium Review coming soon. Creative </a> <a title="EMJ Hepatology 6.1 2018 page 54" href="http://viewer.zmags.com/publication/d158c33c?page=54"> Interact with us on social</a> <a title="EMJ Hepatology 6.1 2018 page 55" href="http://viewer.zmags.com/publication/d158c33c?page=55"> Abstract Reviews A series of abstra</a> <a title="EMJ Hepatology 6.1 2018 page 56" href="http://viewer.zmags.com/publication/d158c33c?page=56"> METHODS A retrospective chart review was performe</a> <a title="EMJ Hepatology 6.1 2018 page 57" href="http://viewer.zmags.com/publication/d158c33c?page=57"> A Comparison of Renal Function Before and </a> <a title="EMJ Hepatology 6.1 2018 page 58" href="http://viewer.zmags.com/publication/d158c33c?page=58"> Table 1: Proportion of hepatitis C patients treat</a> <a title="EMJ Hepatology 6.1 2018 page 59" href="http://viewer.zmags.com/publication/d158c33c?page=59"> were documented, including the use of sorafenib f</a> <a title="EMJ Hepatology 6.1 2018 page 60" href="http://viewer.zmags.com/publication/d158c33c?page=60"> Citation: EMJ Hepatol. 2018;6[1]:59-60. Abstract </a> <a title="EMJ Hepatology 6.1 2018 page 61" href="http://viewer.zmags.com/publication/d158c33c?page=61"> Monocyte-Derived Hepatocyte-Like Cells in Combi</a> <a title="EMJ Hepatology 6.1 2018 page 62" href="http://viewer.zmags.com/publication/d158c33c?page=62"> monocyte-derived hepatocyte-like (MH) cells and p</a> <a title="EMJ Hepatology 6.1 2018 page 63" href="http://viewer.zmags.com/publication/d158c33c?page=63"> Looking for a new job opportunity? </a> <a title="EMJ Hepatology 6.1 2018 page 64" href="http://viewer.zmags.com/publication/d158c33c?page=64"> Primary Hepatic Angiosarcoma: A Brief Review of t</a> <a title="EMJ Hepatology 6.1 2018 page 65" href="http://viewer.zmags.com/publication/d158c33c?page=65"> INTRODUCTION Primary hepatic angiosarcoma (HAS) i</a> <a title="EMJ Hepatology 6.1 2018 page 66" href="http://viewer.zmags.com/publication/d158c33c?page=66"> from diaphragmatic tumour invasion,20 as well as </a> <a title="EMJ Hepatology 6.1 2018 page 67" href="http://viewer.zmags.com/publication/d158c33c?page=67"> increased signal intensity and are generally</a> <a title="EMJ Hepatology 6.1 2018 page 68" href="http://viewer.zmags.com/publication/d158c33c?page=68"> Microscopically, HAS is composed of malignant aty</a> <a title="EMJ Hepatology 6.1 2018 page 69" href="http://viewer.zmags.com/publication/d158c33c?page=69"> have been subclassified based on phenotypical expr</a> <a title="EMJ Hepatology 6.1 2018 page 70" href="http://viewer.zmags.com/publication/d158c33c?page=70"> References 1. Falk H et al. Epidemiology of </a> <a title="EMJ Hepatology 6.1 2018 page 71" href="http://viewer.zmags.com/publication/d158c33c?page=71"> 46. Maluf D et al. Hepatic angiosarcoma </a> <a title="EMJ Hepatology 6.1 2018 page 72" href="http://viewer.zmags.com/publication/d158c33c?page=72"> Acute Fatty Liver of Pregnancy: Better Und</a> <a title="EMJ Hepatology 6.1 2018 page 73" href="http://viewer.zmags.com/publication/d158c33c?page=73"> mortality associated with these disorders can be </a> <a title="EMJ Hepatology 6.1 2018 page 74" href="http://viewer.zmags.com/publication/d158c33c?page=74"> Compensated defect in mitochondrial fatty </a> <a title="EMJ Hepatology 6.1 2018 page 75" href="http://viewer.zmags.com/publication/d158c33c?page=75"> levels were higher in the placenta of AFLP</a> <a title="EMJ Hepatology 6.1 2018 page 76" href="http://viewer.zmags.com/publication/d158c33c?page=76"> Liver dysfunction in second and third trimester o</a> <a title="EMJ Hepatology 6.1 2018 page 77" href="http://viewer.zmags.com/publication/d158c33c?page=77"> MANAGEMENT Prompt suspicion, early recog</a> <a title="EMJ Hepatology 6.1 2018 page 78" href="http://viewer.zmags.com/publication/d158c33c?page=78"> are required to mitigate this complication </a> <a title="EMJ Hepatology 6.1 2018 page 79" href="http://viewer.zmags.com/publication/d158c33c?page=79"> on mechanisms. Obstet Med. 2011;4(3):99-103. 23. </a> <a title="EMJ Hepatology 6.1 2018 page 80" href="http://viewer.zmags.com/publication/d158c33c?page=80"> Targeting the Relaxin Pathway for Liver Disease</a> <a title="EMJ Hepatology 6.1 2018 page 81" href="http://viewer.zmags.com/publication/d158c33c?page=81"> Chronic liver disease affected 29 milli</a> <a title="EMJ Hepatology 6.1 2018 page 82" href="http://viewer.zmags.com/publication/d158c33c?page=82"> Table 1: Summary of preclinical studies investiga</a> <a title="EMJ Hepatology 6.1 2018 page 83" href="http://viewer.zmags.com/publication/d158c33c?page=83"> promoted a matrix-degrading phenotype in</a> <a title="EMJ Hepatology 6.1 2018 page 84" href="http://viewer.zmags.com/publication/d158c33c?page=84"> experimentally induced fibrosis with PPARγ lig</a> <a title="EMJ Hepatology 6.1 2018 page 85" href="http://viewer.zmags.com/publication/d158c33c?page=85"> 40 patients with cirrhosis and hypertension,</a> <a title="EMJ Hepatology 6.1 2018 page 86" href="http://viewer.zmags.com/publication/d158c33c?page=86"> has been demonstrated. It was shown that RX</a> <a title="EMJ Hepatology 6.1 2018 page 87" href="http://viewer.zmags.com/publication/d158c33c?page=87"> 33. Kageyama S et al. Recombinant relaxi</a> <a title="EMJ Hepatology 6.1 2018 page 88" href="http://viewer.zmags.com/publication/d158c33c?page=88"> Thermal Ablation of Liver Tumours: How the Scen</a> <a title="EMJ Hepatology 6.1 2018 page 89" href="http://viewer.zmags.com/publication/d158c33c?page=89"> only available to a restricted number of patients</a> <a title="EMJ Hepatology 6.1 2018 page 90" href="http://viewer.zmags.com/publication/d158c33c?page=90"> quality of life in selected patients, with very l</a> <a title="EMJ Hepatology 6.1 2018 page 91" href="http://viewer.zmags.com/publication/d158c33c?page=91"> Moreover, most studies investigating the </a> <a title="EMJ Hepatology 6.1 2018 page 92" href="http://viewer.zmags.com/publication/d158c33c?page=92"> technical developments that have improved the per</a> <a title="EMJ Hepatology 6.1 2018 page 93" href="http://viewer.zmags.com/publication/d158c33c?page=93"> References 1. World Health Organization. </a> <a title="EMJ Hepatology 6.1 2018 page 94" href="http://viewer.zmags.com/publication/d158c33c?page=94"> 39. Livraghi T et al.; Collaborative Ita</a> <a title="EMJ Hepatology 6.1 2018 page 95" href="http://viewer.zmags.com/publication/d158c33c?page=95"> Percutaneous Laser Thermal Ablation in a Pa</a> <a title="EMJ Hepatology 6.1 2018 page 96" href="http://viewer.zmags.com/publication/d158c33c?page=96"> and modified by Di Costanzo et al.,6 uses 3</a> <a title="EMJ Hepatology 6.1 2018 page 97" href="http://viewer.zmags.com/publication/d158c33c?page=97"> Figure 3: CEUS scan of the right liver lobe after</a> <a title="EMJ Hepatology 6.1 2018 page 98" href="http://viewer.zmags.com/publication/d158c33c?page=98"> times. Among the thermal techniques that can</a> <a title="EMJ Hepatology 6.1 2018 page 99" href="http://viewer.zmags.com/publication/d158c33c?page=99"> Radiology; Standard of Practice Committee of the </a> <a title="EMJ Hepatology 6.1 2018 page 100" href="http://viewer.zmags.com/publication/d158c33c?page=100"> Macrophages in Nonalcoholic Steatohepatitis: Fri</a> <a title="EMJ Hepatology 6.1 2018 page 101" href="http://viewer.zmags.com/publication/d158c33c?page=101"> KUPFFER CELLS Abundancy The liver has an abundanc</a> <a title="EMJ Hepatology 6.1 2018 page 102" href="http://viewer.zmags.com/publication/d158c33c?page=102"> M1 NASH Clear microbes Use of inflammation</a> <a title="EMJ Hepatology 6.1 2018 page 103" href="http://viewer.zmags.com/publication/d158c33c?page=103"> IL- 10 IL -4 IL- 13 PPA R-γ PPA R-δ Th1 Antigen</a> <a title="EMJ Hepatology 6.1 2018 page 104" href="http://viewer.zmags.com/publication/d158c33c?page=104"> thus, unintentionally furthering inflammation by a</a> <a title="EMJ Hepatology 6.1 2018 page 105" href="http://viewer.zmags.com/publication/d158c33c?page=105"> Western-style diet DAMP, IL-33, high motil</a> <a title="EMJ Hepatology 6.1 2018 page 106" href="http://viewer.zmags.com/publication/d158c33c?page=106"> healing response through fibroinflammatory re</a> <a title="EMJ Hepatology 6.1 2018 page 107" href="http://viewer.zmags.com/publication/d158c33c?page=107"> by inhibiting TGF-β mediated myofibroblast act</a> <a title="EMJ Hepatology 6.1 2018 page 108" href="http://viewer.zmags.com/publication/d158c33c?page=108"> References 1. Williams CD et al. Prevalence </a> <a title="EMJ Hepatology 6.1 2018 page 109" href="http://viewer.zmags.com/publication/d158c33c?page=109"> 45. Ibusuki R et al. Transgenic expression </a> <a title="EMJ Hepatology 6.1 2018 page 110" href="http://viewer.zmags.com/publication/d158c33c?page=110"> Coming soon. EMJ prov</a> <a title="EMJ Hepatology 6.1 2018 page 111" href="http://viewer.zmags.com/publication/d158c33c?page=111"> Buyer's Guide > ABBVIE INC. > ADVANCED BIOLOGICAL</a> <a title="EMJ Hepatology 6.1 2018 page 112" href="http://viewer.zmags.com/publication/d158c33c?page=112"> Never miss an update again. J</a>